EP4743093A1 - Metabolites for TRNA Modification - Google Patents

Metabolites for TRNA Modification

Info

Publication number
EP4743093A1
EP4743093A1 EP24840579.7A EP24840579A EP4743093A1 EP 4743093 A1 EP4743093 A1 EP 4743093A1 EP 24840579 A EP24840579 A EP 24840579A EP 4743093 A1 EP4743093 A1 EP 4743093A1
Authority
EP
European Patent Office
Prior art keywords
metabolites
trna modification
trna
modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24840579.7A
Other languages
German (de)
French (fr)
Inventor
Tao Pan
Wen Zhang
Hélène Guillorit
Alexandre David
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut National de la Sante et de la Recherche Medicale INSERM
Universite de Montpellier
Institut Regional du Cancer de Montpellier
University of Chicago
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut National de la Sante et de la Recherche Medicale INSERM
Universite de Montpellier
Institut Regional du Cancer de Montpellier
University of Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Institut National de la Sante et de la Recherche Medicale INSERM, Universite de Montpellier, Institut Regional du Cancer de Montpellier, University of Chicago filed Critical Centre National de la Recherche Scientifique CNRS
Publication of EP4743093A1 publication Critical patent/EP4743093A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP24840579.7A 2023-07-11 2024-07-11 Metabolites for TRNA Modification Pending EP4743093A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23306191 2023-07-11
PCT/US2024/037646 WO2025015197A1 (en) 2023-07-11 2024-07-11 Metabolites for trna modification

Publications (1)

Publication Number Publication Date
EP4743093A1 true EP4743093A1 (en) 2026-05-20

Family

ID=87933712

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24840579.7A Pending EP4743093A1 (en) 2023-07-11 2024-07-11 Metabolites for TRNA Modification

Country Status (2)

Country Link
EP (1) EP4743093A1 (en)
WO (1) WO2025015197A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240247250A1 (en) * 2021-05-24 2024-07-25 The Regents Of The University Of California Compositions and methods for modifying dna

Also Published As

Publication number Publication date
WO2025015197A1 (en) 2025-01-16

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