EP4743082A1 - Carbazole compounds and their use in therapy for the treatment of respiratory infections - Google Patents

Carbazole compounds and their use in therapy for the treatment of respiratory infections

Info

Publication number
EP4743082A1
EP4743082A1 EP24745493.7A EP24745493A EP4743082A1 EP 4743082 A1 EP4743082 A1 EP 4743082A1 EP 24745493 A EP24745493 A EP 24745493A EP 4743082 A1 EP4743082 A1 EP 4743082A1
Authority
EP
European Patent Office
Prior art keywords
therapy
treatment
respiratory infections
carbazole compounds
carbazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24745493.7A
Other languages
German (de)
French (fr)
Inventor
Helen Hailes
Liam Martin
Sanjib Bhakta
Christine Daniel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCL Business Ltd
Birkbeck University of London
Original Assignee
UCL Business Ltd
Birkbeck University of London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCL Business Ltd, Birkbeck University of London filed Critical UCL Business Ltd
Publication of EP4743082A1 publication Critical patent/EP4743082A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP24745493.7A 2023-07-10 2024-07-09 Carbazole compounds and their use in therapy for the treatment of respiratory infections Pending EP4743082A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB202310572 2023-07-10
PCT/GB2024/051790 WO2025012634A1 (en) 2023-07-10 2024-07-09 Carbazole compounds and their use in therapy, in the treatment of a respiratory infection

Publications (1)

Publication Number Publication Date
EP4743082A1 true EP4743082A1 (en) 2026-05-20

Family

ID=91959355

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24745493.7A Pending EP4743082A1 (en) 2023-07-10 2024-07-09 Carbazole compounds and their use in therapy for the treatment of respiratory infections

Country Status (2)

Country Link
EP (1) EP4743082A1 (en)
WO (1) WO2025012634A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2986338T3 (en) * 2017-04-11 2024-11-11 Gsno Therapeutics Inc Carbazole compounds and methods of using them

Also Published As

Publication number Publication date
WO2025012634A1 (en) 2025-01-16

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