EP4682670A1 - Circuit arrangement for use in an implantable medical device - Google Patents

Circuit arrangement for use in an implantable medical device

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Publication number
EP4682670A1
EP4682670A1 EP24188848.6A EP24188848A EP4682670A1 EP 4682670 A1 EP4682670 A1 EP 4682670A1 EP 24188848 A EP24188848 A EP 24188848A EP 4682670 A1 EP4682670 A1 EP 4682670A1
Authority
EP
European Patent Office
Prior art keywords
mosfet
temperature
circuit arrangement
transistor
mosfet transistors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24188848.6A
Other languages
German (de)
French (fr)
Inventor
Markus Wiesheier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotronik SE and Co KG
Original Assignee
Biotronik SE and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotronik SE and Co KG filed Critical Biotronik SE and Co KG
Priority to EP24188848.6A priority Critical patent/EP4682670A1/en
Publication of EP4682670A1 publication Critical patent/EP4682670A1/en
Pending legal-status Critical Current

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Classifications

    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05FSYSTEMS FOR REGULATING ELECTRIC OR MAGNETIC VARIABLES
    • G05F3/00Non-retroactive systems for regulating electric variables by using an uncontrolled element, or an uncontrolled combination of elements, such element or such combination having self-regulating properties
    • G05F3/02Regulating voltage or current
    • G05F3/08Regulating voltage or current wherein the variable is DC
    • G05F3/10Regulating voltage or current wherein the variable is DC using uncontrolled devices with non-linear characteristics
    • G05F3/16Regulating voltage or current wherein the variable is DC using uncontrolled devices with non-linear characteristics being semiconductor devices
    • G05F3/20Regulating voltage or current wherein the variable is DC using uncontrolled devices with non-linear characteristics being semiconductor devices using diode- transistor combinations
    • G05F3/30Regulators using the difference between the base-emitter voltages of two bipolar transistors operating at different current densities
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05FSYSTEMS FOR REGULATING ELECTRIC OR MAGNETIC VARIABLES
    • G05F3/00Non-retroactive systems for regulating electric variables by using an uncontrolled element, or an uncontrolled combination of elements, such element or such combination having self-regulating properties
    • G05F3/02Regulating voltage or current
    • G05F3/08Regulating voltage or current wherein the variable is DC
    • G05F3/10Regulating voltage or current wherein the variable is DC using uncontrolled devices with non-linear characteristics
    • G05F3/16Regulating voltage or current wherein the variable is DC using uncontrolled devices with non-linear characteristics being semiconductor devices
    • G05F3/20Regulating voltage or current wherein the variable is DC using uncontrolled devices with non-linear characteristics being semiconductor devices using diode- transistor combinations
    • G05F3/24Regulating voltage or current wherein the variable is DC using uncontrolled devices with non-linear characteristics being semiconductor devices using diode- transistor combinations wherein the transistors are of the field-effect type only
    • G05F3/242Regulating voltage or current wherein the variable is DC using uncontrolled devices with non-linear characteristics being semiconductor devices using diode- transistor combinations wherein the transistors are of the field-effect type only with compensation for device parameters, e.g. channel width modulation, threshold voltage, processing, or external variations, e.g. temperature, loading, supply voltage

Definitions

  • the instant invention relates to a circuit arrangement for use in an implantable medical device and to an implantable medical device comprising such a circuit arrangement.
  • a circuit arrangement of this kind is configured for providing a temperature-compensated output resistance.
  • a circuit arrangement of this kind shall be employed in a processing circuitry of an implantable medical device.
  • An implantable medical device of this kind may for example be a cardiac stimulation device, such as a cardiac pacemaker device or a cardiac defibrillator device.
  • the implantable medical device is a cardiac resynchronization therapy device (CRT), for example comprising a defibrillation function (CRT-D).
  • CRT cardiac resynchronization therapy device
  • the implantable medical device is an implantable cardioverter defibrillator (ICD).
  • the implantable medical device is an implantable neuro-stimulation device, an implantable sensor device such as a pressure sensing device, or an implantable monitoring device such as a bio-monitor for monitoring and recording signals within a patient.
  • implantable medical devices such as implantable stimulation devices
  • a processing circuitry of an implantable medical device hence shall operate in a power-efficient manner to allow for a continuous operation in an implanted state, despite strict space constraints imposed on a device battery.
  • CMOS analog circuit design employing (p-channel or n-channel) MOSFET transistors.
  • CMOS analog circuit design allows for a design of analog integrated circuits by modelling analog circuit components such as resistances or inductances by an arrangement of MOSFET transistors in a power-efficient and at the same time space-efficient and or area-efficient manner.
  • a resistance in combination with a capacitance is generally required to provide for a filtering circuit in order to tune the communication circuitry to a desired frequency band.
  • a temperature stability of the resistance is desirable.
  • a circuit arrangement for use in an implantable medical device is configured for providing a temperature-compensated output resistance and comprises a first MOSFET transistor, a first circuit portion configured to supply a temperature-dependent reference current to the first MOSFET transistor, and a second circuit portion configured to generate a temperature-dependent output voltage across a drain and a source of the first MOSFET transistor, such that an ON resistance of the first MOSFET transistor resulting from the output voltage and the reference current provides the temperature-compensated output resistance.
  • the circuit arrangement comprises a first MOSFET transistor, a first circuit portion and a second circuit portion.
  • the first circuit portion during operation of the circuit arrangement, supplies a temperature-dependent reference current to the first MOSFET transistor, in particular to the drain of the first MOSFET transistor.
  • the second circuit portion in turn, generates a temperature-dependent output voltage across the first MOSFET transistor, namely a drain-source voltage across the drain and the source of the first MOSFET transistor. If the temperature dependency of the reference current and the temperature dependency of the output voltage are substantially equal, the temperature dependency of the reference current and the temperature dependency of the output voltage cancel each other out at the first MOSFET transistor, such that an ON resistance of the first MOSFET transistor results which is substantially temperature independent and hence yields a temperature-compensated output resistance.
  • the ON resistance of the first MOSFET transistor is computed by dividing the voltage across the drain and the source of the first MOSFET transistor, namely the temperature-dependent output voltage provided by the second circuit portion, by the current flowing from drain to source, imposed by the temperature-dependent reference current. If the temperature dependency of the reference current and the temperature dependency of the output voltage are substantially equal, the temperature dependencies will substantially cancel out, such that a temperature-independent ON resistance results, yielding the temperature-compensated output resistance.
  • the first MOSFET transistor is configured to operate in a linear region of MOSFET operation.
  • the drain-source voltage is smaller than a saturation voltage.
  • the drain current (at least on a small scale) linearly depends on the drain-source voltage (in comparison to the saturated region, in which the drain current substantially is independent of the drain-source voltage).
  • the first MOSFET transistor shall be dimensioned such that its saturation voltage is larger than the output voltage supplied by the second circuit portion in order to ensure an operation in the linear region.
  • the temperature-dependent reference current comprises a first temperature dependency and the temperature-dependent output voltage comprises a second temperature dependency, wherein the first temperature dependency and the second temperature dependency are at least approximately equal.
  • the reference current as provided by the first circuit portion of the circuit arrangement and the output voltage as generated by the second circuit portion of the circuit arrangement comprise a substantially equal temperature dependency
  • the temperature dependencies of the reference current and the output voltage cancel out at the first MOSFET transistor, such that the first MOSFET transistor exhibits a substantially temperature-independent ON resistance, providing the temperature-compensated output resistance.
  • the gate voltage of the first MOSFET transistor will automatically regulate itself such that the ON resistance determined by the drain-source resistance is set according to the reference current supplied to the first MOSFET transistor and the output voltage applied across the drain and the source.
  • the second circuit portion comprises a pair of second MOSFET transistors, wherein gates of the second MOSFET transistors are connected to each other.
  • the second MOSFET transistors are connected to one another such that the output voltage is generated and is applied across the drain and the source of the first MOSFET transistor.
  • the value of the output voltage corresponding to a difference voltage (delta voltage) of the source potentials of the second MOSFET transistors, depends on the dimensions of the second MOSFET transistors, namely a channel width and a channel length of each of the second MOSFET transistors.
  • Factor 1.Y is produced via a multiplier.
  • the second MOSFET transistors are configured to operate in a weak inversion region of MOSFET operation.
  • the gate-source voltage of the second MOSFET transistors is smaller than a threshold voltage associated with the respective MOSFET transistor. Operation in the weak inversion region generally can be ensured by properly dimensioning the second MOSFET transistors, in particular the channel width and channel length of the second MOSFET transistors.
  • the second MOSFET transistors are dimensioned to be large such that a small gate-source voltage results.
  • the first circuit portion is connected to drains of the second MOSFET transistors to supply the reference current to the drains of the second MOSFET transistors.
  • the first circuit portion which in operation supplies the temperature-dependent reference current, hence is connected to the drains of the second MOSFET transistors in order to feed the temperature-dependent reference current alike into the second MOSFET transistors.
  • the temperature-dependent reference current hence is imposed on the second MOSFET transistors, which hence each comprise a drain-source current as set by to the reference current.
  • the drain of one of the second MOSFET transistors is connected to a gate of the first MOSFET transistor.
  • the drain of the respective second MOSFET transistor generally is in a high-ohmic state.
  • the drain of the second MOSFET transistor is connected to the gate of the first MOSFET transistor, such that the drain of the respective second MOSFET transistor and the gate of the first MOSFET transistor are at equal potential.
  • the source of said one of the second MOSFET transistors is connected to the drain of the first MOSFET transistor.
  • the source of the first MOSFET transistor is connected for example to ground, or may be connected to a voltage source or another MOSFET transistor in order to provide for a voltage shift at the source of the first MOSFET transistor.
  • the first MOSFET transistor hence is arranged in between the source of the respective one of the second MOSFET transistors and ground (or a voltage source or another MOSFET transistor in the path towards ground).
  • the drain and the gate of the other of the second MOSFET transistors are connected to each other.
  • the drain and the gate of the other of the second MOSFET transistors hence are short-circuited and are at the same potential.
  • the second MOSFET transistors together provide for the voltage corresponding to a difference voltage (delta voltage) in between the sources of the two second MOSFET transistors.
  • Said voltage can be the output voltage, or generating the output voltage with other voltage sources or another MOSFET transistor in the path toward ground.
  • the first circuit portion comprises a pair of third MOSFET transistors.
  • the gates of the third MOSFET transistors are connected to each other, such that the gates of the third MOSFET transistors are at equal potential.
  • the third MOSFET transistors are configured to operate in a weak inversion region of MOSFET operation.
  • the first circuit portion is operated such that the gate-source voltage of both of the third MOSFET transistors is smaller than a threshold voltage associated with the respective MOSFET transistor.
  • the third MOSFET transistors may for example be dimensioned large, i.e. to comprise a comparatively large channel width and length.
  • the first circuit portion comprises a pair of fourth MOSFET transistors connected at their gates and serving as a current mirror.
  • the pair of fourth MOSFET transistors is connected to the pair of third MOSFET transistors such that a drain of each of the fourth MOSFET transistors is connected to a drain of one of the third MOSFET transistors.
  • the pair of fourth MOSFET transistors functions as a current mirror, an equal current is passed through the pair of third MOSFET transistors.
  • the pair of fourth MOSFET transistors are p-type MOSFET transistors, or PMOS transistors, wherein the pair of first, second and third MOSFET transistors are NMOS transistors.
  • the pair of fourth MOSFET transistors have the source on the Vcc side. The voltages from source to drain and from source to gate are of positive polarity.
  • the drain of one of the MOSFET transistors from the pair of fourth MOSFET transistors and the connected drain of one of the third MOSFET transistors are connected to a third circuit portion.
  • the third circuit portion comprises a pair of fifth MOSFET transistors connected at their gates and serving as a current mirror.
  • an equal current for instance a reference current I REF , is passed through the pair of fifth MOSFET transistors.
  • the pair of fifth MOSFET transistors are PMOS transistors, having the source on the Vcc side.
  • the voltages from source to drain and from source to gate are of positive polarity.
  • the MOSFET transistors of the pair of fifth MOSFET transistors are dimensioned with equal channel width W divided by channel length L, as the W/L of one MOSFET transistor of the pair of fourth MOSFET transistors.
  • one of the third MOSFET transistors at its source is connected to a non-temperature-dependent resistance.
  • the first circuit portion is configured to output the reference current according to a reference voltage produced across the non-temperature-dependent resistance.
  • the reference voltage is produced as a difference voltage (delta voltage) between the pair of third MOSFET transistors and comprises a temperature dependency in accordance with the temperature dependency of the third MOSFET transistors.
  • the reference voltage is applied across the non-temperature-dependent reference resistance, the reference current results which exhibits a temperature dependency according to the temperature dependency of operation of the third MOSFET transistors.
  • the temperature dependency of the first circuit portion for providing the temperature-dependent reference current is largely governed by the pair of third MOSFET transistors
  • the temperature dependency of the second circuit portion for providing the temperature-dependent output voltage is largely governed by the pair of second MOSFET transistors.
  • the gate of the first MOSFET transistor is connected to a gate of a target (MOSFET) transistor to produce a temperature-independent ON resistance at the target transistor.
  • the first MOSFET transistor in particular may function as a reference to control any target MOSFET transistor to obtain a substantially constant (temperature-independent) ON resistance.
  • an implantable medical device for performing a therapeutic and/or diagnostic function in a patient comprises a circuit arrangement of the kind described above.
  • the implantable medical device in particular may be a stimulation device, such as a cardiac stimulation device or a neuro-stimulation device.
  • the implantable medical device may be a cardiac pacemaker device or a cardiac defibrillator device, such as a CRT device or an ICD device.
  • the implantable medical device may for example be an implantable sensor device or an implantable monitoring device.
  • a system comprises an implantable medical device 1 implanted into a patient for serving a therapeutic cardiac stimulation function.
  • the implantable medical device comprises a generator device 10 and an arrangement of electrode leads 11, 12, 13 extending from the generator device 10.
  • the generator device 10 may for example be implanted subcutaneously into a patient P, the electrode leads 11, 12, 13 reaching into the patient's heart for monitoring cardiac activity of the patient's heart.
  • the generator device 10 comprises a processing circuitry 14 encapsulated in a housing of the generator device 10 together with an electrochemical battery for supplying electrical energy for operation of the implantable medical device 1.
  • the system furthermore comprises an external device 2 external to the patient P and being in communication connection with the implantable medical device 1.
  • the external device 2 may be in connection, via a public communication network 4, with a remote server device 3, for example a home monitoring service center (HMSC) accessible by a physician, in the context of a home monitoring system.
  • HMSC home monitoring service center
  • another type of external device (not depicted) is used to communicate with the implantable medical device 1 using a first communication coil in the external device and a second communication coil in the implantable medical device.
  • the external device is brought in proximity (about 10 cm) to the implantable medical device 1 to achieve inductive coupling between the two coils, enabling data exchange.
  • the receiver circuit in the implantable medical device 1 for said coil communication is limited in space and area, and exposed to temperature variations.
  • resistances can be generated which are constant in regard to with temperature changes and processing variations.
  • the described circuit arrangement(s) can be used for telemetry integrated circuits of implantable medical device 1.
  • the processing circuitry 14 is configured for providing a therapeutic and/or diagnostic function using the implantable medical device 1.
  • the processing circuitry 14 may be embodied to establish a communication connection to an external device 2 and for this may comprise circuitry in order to establish a communication for example using RF signals.
  • the implantable medical device 1 for example a cardiac stimulation device such as a pacemaker device or a defibrillator device, for example a CRT device or an ICD device, generally shall be designed such that it may rest within a patient P over a prolonged duration of time, making it necessary for the implantable medical device 1 to function in an energy-efficient manner by using energy resources of a battery encapsulated within a housing of the implantable medical device 1.
  • a cardiac stimulation device such as a pacemaker device or a defibrillator device, for example a CRT device or an ICD device
  • a CRT device or an ICD device generally shall be designed such that it may rest within a patient P over a prolonged duration of time, making it necessary for the implantable medical device 1 to function in an energy-efficient manner by using energy resources of a battery encapsulated within a housing of the implantable medical device 1.
  • As severe space restrictions exist for components of the implantable medical device 1, including the processing circuitry 14 and the battery it is important to design the implantable medical device
  • the processing circuitry 14 generally, in order to provide for a power-efficient operation and space-efficient structure, is designed using CMOS analog circuit design.
  • components of the processing circuitry 14, such as resistances or inductances, may be modeled using arrangements of MOSFET transistors.
  • a circuit arrangement 140 of the processing circuitry 14 is configured for setting an output resistance at the target transistor M4.
  • the output resistance is set at the target transistor M4 by controlling the gate voltage at the gate G of the target transistor M4 and shall be such that it is substantially temperature independent in order to provide for a temperature-stable resistance.
  • Resistances in the processing circuitry 14 may serve different purposes.
  • a resistance may be combined in a communication circuitry with a capacitance in order to provide for a filtering circuit to tune the communication circuitry to a desired frequency band of communication.
  • a temperature-stable operation is desired to allow for a stable communication in a specific, for example narrow frequency band, taking into account that within a patient P temperature conditions are substantially different than outside of the patient P and in addition may vary over time.
  • a temperature-compensated output resistance is set at a MOSFET transistor M3 and also at the target transistor M4 by controlling the gate voltage at the gate G of the target transistor M4 using the MOSFET transistor M3.
  • the circuit arrangement 140 comprises a first circuit portion configured for delivering a reference current I REF , denoted in Fig. 2 by current sources and shown in an embodiment in Fig. 3 .
  • the circuit arrangement 140 according to Fig. 2 comprises a second circuit portion made up of MOSFET transistors M1, M2, which are fed at their drains D with the reference current I REF and are connected to one another at their gates G.
  • MOSFET transistors M1, M2 - in the example of Fig. 2 the MOSFET transistor M2 - at its source S is connected to the drain D of the MOSFET transistor M3.
  • the drain D of the MOSFET transistor M2 is connected to the gate G of the MOSFET transistor M3, such that the gate voltage V gate of the MOSFET transistor M3 is drawn to the high-ohmic drain D of the MOSFET transistor M2.
  • the drain D of the MOSFET transistor M1 is connected (short-circuited) to its gate G.
  • any MOSFET transistor as concerned herein comprises a drain D, a source S and a gate G as well-known in the art and as typical for a MOSFET transistor.
  • an output voltage V R is applied across the drain D and the source S of the MOSFET transistor M3, as it is indicated in Fig. 2 .
  • the output voltage V R herein is provided as a difference voltage (delta voltage) in between the sources S of the MOSFET transistors M1, M2.
  • the MOSFET transistors M1, M2 operate in a weak inversion region of MOSFET operation.
  • the gate-source voltage is below a threshold voltage (generally denoted as V T in the literature)
  • the gate-source voltage is above the threshold voltage.
  • the MOSFET transistor M3 in turn, operates in the linear region, in which the drain-source voltage is below a saturation voltage, as it is indicated in Fig. 6 and as it is commonly known in MOSFET technology.
  • V R V Temp ⁇ ln Y
  • k B Boltzmann constant
  • T absolute temperature in Kelvin
  • e elementary charge
  • the output voltage V R comprises a temperature dependency according to the temperature voltage V Temp .
  • the reference current I REF is provided to comprise a temperature dependency which at least is similar to the temperature dependency of the output voltage V R , such that according to equation (4) the temperature dependencies cancel each other out, and a substantially constant output resistance R ON , M3 R DS,M3 results.
  • the reference current I REF is provided by a circuit portion 141 as illustrated in the circuit schematic of Fig. 3 .
  • the circuit portion 141 comprises a pair of MOSFET transistors M5, M6, which are connected to each other at their gates G.
  • a pair of further MOSFET transistors M7, M8, which are PMOS transistors, have the source on the Vcc side.
  • the voltages from source to drain and from source to gate are of positive polarity.
  • M7, M8 function as a current mirror and is formed equal, the MOSFET transistors M7, M8 being connected at their sources S to a supply voltage VCC and at their drains D to the drains D of the MOSFET transistors M5, M6, as this is shown in Fig. 3 .
  • the gate G of the MOSFET transistor M8 herein is connected (short-circuited) to its drain D.
  • the drain D of the MOSFET transistor M5 is connected (short-circuited) to its gate G.
  • the drain of M8 and the drain of connected M6 are connected to another circuit portion 144.
  • the circuit portion 144 comprises a pair of MOSFET transistors M11, M12 which are connected at their gates and serving as a current mirror.
  • an equal current for instance a reference current I REF , is passed through the pair of MOSFET transistors M11, M12.
  • the pair of MOSFET transistors M11, M12 are PMOS transistors, having the source on the Vcc side.
  • the voltages from source to drain and from source to gate are of positive polarity.
  • the MOSFET transistors of M11, M12 are dimensioned with equal channel width W divided by channel length L, as the W/L of one MOSFET transistors M8 or M9, for example M8.
  • MOSFET transistors M7, M8 function as a current mirror with factor 1:1 or other factors, they impose an identical reference current I REF through the MOSFET transistors M5, M6, such that the drain currents of both MOSFET transistors M5, M6 are equal and correspond to the reference current I REF .
  • the MOSFET transistor M6 at its source S is connected to a reference resistance R REF which comprises a substantially temperature-independent, constant resistance.
  • MOSFET transistors M5, M6 both operate in the weak inversion region.
  • V REF V Temp ⁇ ln I D , M 5 I D , M 6 X
  • V Temp again is the temperature voltage
  • the gate voltage of the MOSFET transistor M3 will regulate itself according to the output voltage V R and the imposed reference current I REF such that an output resistance, corresponding to the drain-source resistance, results which fulfills the equation (4) above.
  • the output resistance in addition is independent in this respect.
  • the gate voltage of the MOSFET transistor M3 serves as a reference voltage for the target transistor M4 and potential further MOSFET transistors, which shall exhibit a defined, temperature-compensated ON resistance.
  • the controlled gate voltage of the MOSFET transistor M3 thus provides for a compensation of temperature variations in the target transistors M4.
  • An adaption of a resistance value may be provided by adjusting the transistor geometry of the respective target transistor M4, wherein the output resistance (ON resistance) is indirectly proportional to the ratio of channel width and channel length.
  • M1, M2 M5 and M6 are in weak inversion region and in saturation.
  • M7, M8 and IREF are saturated, wherein M7 and M8 may be in weak inversion, strong inversion or moderate inversion region.
  • M3 should be dimensioned so that M2 operates in saturated mode over the entire target temperature range and the I REF current source is not affected (i.e. the I REF transistor always remains saturated).
  • M5/M6 and M7/M8 Saturated operation should be ensured for all of them.
  • a small error may result in case a current flow through the transistors M3 and M4 differs and due to the exponential characteristic of the ON resistance (see Fig. 6 ).
  • the bias current/voltage is approximately 0 and the ON resistance in effect acts only dynamically.
  • An improved operation may be possible by separating the transistors M3 and M4 into multiple serially connected MOSFET transistors of equal size, such that the output voltage V R is equally distributed across the serially connected MOSFET transistors.
  • the MOSFET transistor M3 is not connected directly to ground, but in addition a voltage source V1 is arranged in the path between the source S of the MOSFET transistor M3 towards ground. In this way a voltage shift by the voltage V1 may be obtained.
  • circuit arrangement 142 of Fig. 4 is functionally identical to the circuit arrangement 140 of Fig. 2 .
  • a MOSFET transistor M9 may be connected in between the source S of the MOSFET transistor M3 and ground, as illustrated in Fig. 5 .
  • a MOSFET transistor M10 may be connected in between the source S of the MOSFET transistor M4 and ground.
  • the voltage V2 across the MOSFET transistor M9 may be set equal to the voltage V1 between the source S of the MOSFET transistor M4 and ground by suitably designing the drain current of the MOSFET transistor M10 and the channel width and channel length of the MOSFET transistor M9.
  • circuit arrangement 143 of Fig. 5 is functionally identical to the circuit arrangement 140 of Fig. 2 .
  • MOSFET transistors M1, M2 in the circuit arrangement 140 of Fig. 2 and likewise in the circuit arrangement 142 of Fig. 4 and the circuit arrangement 143 of Fig. 5 may also be implemented by bipolar transistors.
  • the reference current I REF may generally lie in a range between 10 nA and 100 nA, for example at around 20 nA.
  • the output voltage V R may generally lie in a range between 35 mV to 60 mV.
  • the ON resistance of the MOSFET transistor M3 may for example have a resistance value in between 500 kOhm to 6 MOhm, wherein the ON resistance of the MOSFET transistor M4 may have a scaling factor from 1 to 100 compared to the resistance of M3, which is resistance value in between 500 kOhm to 600 MOhm.
  • the implantable medical device may be for example an ICD or a CRT-D device or another pacemaker device.
  • the implantable medical device may comprise electrode leads carrying electrode poles, which may be implanted to reach into the patient's heart, or may rest fully outside of the patient's heart when they are implanted in the patient.
  • the implantable medical device is a leadless device not comprising electrode leads.

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  • Microelectronics & Electronic Packaging (AREA)
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Abstract

A circuit arrangement (140-144) for use in an implantable medical device (1) is configured for providing a temperature-compensated output resistance and comprises a first MOSFET transistor (M3), a first circuit portion configured to supply a temperature-dependent reference current (IREF) to the first MOSFET transistor (M3), and a second circuit portion configured to generate a temperature-dependent output voltage (VR) across a drain (D) and a source (S) of the first MOSFET transistor (M3), such that an ON resistance (RON,M3) of the first MOSFET transistor (M3) resulting from the output voltage (VR) and the reference current (IREF) provides the temperature-compensated output resistance.

Description

  • The instant invention relates to a circuit arrangement for use in an implantable medical device and to an implantable medical device comprising such a circuit arrangement.
  • A circuit arrangement of this kind is configured for providing a temperature-compensated output resistance.
  • A circuit arrangement of this kind shall be employed in a processing circuitry of an implantable medical device. An implantable medical device of this kind may for example be a cardiac stimulation device, such as a cardiac pacemaker device or a cardiac defibrillator device. For example, the implantable medical device is a cardiac resynchronization therapy device (CRT), for example comprising a defibrillation function (CRT-D). In another embodiment, the implantable medical device is an implantable cardioverter defibrillator (ICD). In yet another embodiment, the implantable medical device is an implantable neuro-stimulation device, an implantable sensor device such as a pressure sensing device, or an implantable monitoring device such as a bio-monitor for monitoring and recording signals within a patient.
  • Generally, implantable medical devices, such as implantable stimulation devices, shall be small in size and shall be configured for operating within a patient for a prolonged period of time. A processing circuitry of an implantable medical device hence shall operate in a power-efficient manner to allow for a continuous operation in an implanted state, despite strict space constraints imposed on a device battery.
  • Analog integrated circuits within a processing circuitry of an implantable medical device typically are implemented using a CMOS analog circuit design employing (p-channel or n-channel) MOSFET transistors. CMOS analog circuit design allows for a design of analog integrated circuits by modelling analog circuit components such as resistances or inductances by an arrangement of MOSFET transistors in a power-efficient and at the same time space-efficient and or area-efficient manner.
  • In particular within the design of circuits for use in an implantable medical device, space efficiency is of importance. In addition, when for example designing a resistance in CMOS technology, it is desirous to be able to provide large resistance values which are substantially temperature independent, taking into account that within a patient temperature conditions typically are substantially different than outside of the patient and may vary within the patient.
  • For example, when designing a circuit to be used in a communication circuitry for establishing a communication between the implantable medical device and an external device, a resistance in combination with a capacitance is generally required to provide for a filtering circuit in order to tune the communication circuitry to a desired frequency band. For this, in order to allow for a frequency-stable operation, a temperature stability of the resistance is desirable.
  • Current approaches for designing a resistance using CMOS technology, for example by using so-called poly-resistances, may suffer from comparatively large space or area requirements or do not allow for a satisfactory temperature compensation.
  • It is an object of the instant invention to provide a circuit arrangement and an implantable medical device using such circuit arrangement which allow for a temperature-compensated operation.
  • This object is achieved by means of a circuit arrangement comprising the features of claim 1.
  • Accordingly, a circuit arrangement for use in an implantable medical device is configured for providing a temperature-compensated output resistance and comprises a first MOSFET transistor, a first circuit portion configured to supply a temperature-dependent reference current to the first MOSFET transistor, and a second circuit portion configured to generate a temperature-dependent output voltage across a drain and a source of the first MOSFET transistor, such that an ON resistance of the first MOSFET transistor resulting from the output voltage and the reference current provides the temperature-compensated output resistance.
  • The circuit arrangement comprises a first MOSFET transistor, a first circuit portion and a second circuit portion. The first circuit portion, during operation of the circuit arrangement, supplies a temperature-dependent reference current to the first MOSFET transistor, in particular to the drain of the first MOSFET transistor. The second circuit portion, in turn, generates a temperature-dependent output voltage across the first MOSFET transistor, namely a drain-source voltage across the drain and the source of the first MOSFET transistor. If the temperature dependency of the reference current and the temperature dependency of the output voltage are substantially equal, the temperature dependency of the reference current and the temperature dependency of the output voltage cancel each other out at the first MOSFET transistor, such that an ON resistance of the first MOSFET transistor results which is substantially temperature independent and hence yields a temperature-compensated output resistance.
  • The ON resistance of the first MOSFET transistor is computed by dividing the voltage across the drain and the source of the first MOSFET transistor, namely the temperature-dependent output voltage provided by the second circuit portion, by the current flowing from drain to source, imposed by the temperature-dependent reference current. If the temperature dependency of the reference current and the temperature dependency of the output voltage are substantially equal, the temperature dependencies will substantially cancel out, such that a temperature-independent ON resistance results, yielding the temperature-compensated output resistance.
  • In one embodiment, the first MOSFET transistor is configured to operate in a linear region of MOSFET operation. Generally, to operate in the linear region, the drain-source voltage is smaller than a saturation voltage. In the linear region the drain current (at least on a small scale) linearly depends on the drain-source voltage (in comparison to the saturated region, in which the drain current substantially is independent of the drain-source voltage).
  • To operate in the linear region, the first MOSFET transistor shall be dimensioned such that its saturation voltage is larger than the output voltage supplied by the second circuit portion in order to ensure an operation in the linear region.
  • Operation in the linear region is well-known in CMOS technology and is described in detail for example in the textbook by Phillip E. Allen and Douglas R. Holberg, "CMOS analog circuit design", 1987, ISBN 0-19-510720-9.
  • In one embodiment, the temperature-dependent reference current comprises a first temperature dependency and the temperature-dependent output voltage comprises a second temperature dependency, wherein the first temperature dependency and the second temperature dependency are at least approximately equal. In that the reference current as provided by the first circuit portion of the circuit arrangement and the output voltage as generated by the second circuit portion of the circuit arrangement comprise a substantially equal temperature dependency, the temperature dependencies of the reference current and the output voltage cancel out at the first MOSFET transistor, such that the first MOSFET transistor exhibits a substantially temperature-independent ON resistance, providing the temperature-compensated output resistance. In particular, the gate voltage of the first MOSFET transistor will automatically regulate itself such that the ON resistance determined by the drain-source resistance is set according to the reference current supplied to the first MOSFET transistor and the output voltage applied across the drain and the source.
  • In one embodiment, the second circuit portion comprises a pair of second MOSFET transistors, wherein gates of the second MOSFET transistors are connected to each other. The second MOSFET transistors are connected to one another such that the output voltage is generated and is applied across the drain and the source of the first MOSFET transistor.
  • The value of the output voltage, corresponding to a difference voltage (delta voltage) of the source potentials of the second MOSFET transistors, depends on the dimensions of the second MOSFET transistors, namely a channel width and a channel length of each of the second MOSFET transistors.
  • In one embodiment, the second MOSFET transistors are dimensioned with equal channel width W divided by channel length L, W/L=Y. Factor 1.Y is produced via a multiplier.
  • In one embodiment, the second MOSFET transistors are configured to operate in a weak inversion region of MOSFET operation. Generally, in the weak inversion region the gate-source voltage of the second MOSFET transistors is smaller than a threshold voltage associated with the respective MOSFET transistor. Operation in the weak inversion region generally can be ensured by properly dimensioning the second MOSFET transistors, in particular the channel width and channel length of the second MOSFET transistors. Generally, the second MOSFET transistors are dimensioned to be large such that a small gate-source voltage results.
  • Operation in the weak inversion region is well-known in CMOS technology and is described in detail for example in the textbook by Phillip E. Allen and Douglas R. Holberg, "CMOS analog circuit design", 1987, ISBN 0-19-510720-9.
  • In one embodiment, the first circuit portion is connected to drains of the second MOSFET transistors to supply the reference current to the drains of the second MOSFET transistors. The first circuit portion, which in operation supplies the temperature-dependent reference current, hence is connected to the drains of the second MOSFET transistors in order to feed the temperature-dependent reference current alike into the second MOSFET transistors. The temperature-dependent reference current hence is imposed on the second MOSFET transistors, which hence each comprise a drain-source current as set by to the reference current.
  • In one embodiment, the drain of one of the second MOSFET transistors is connected to a gate of the first MOSFET transistor. The drain of the respective second MOSFET transistor generally is in a high-ohmic state. The drain of the second MOSFET transistor is connected to the gate of the first MOSFET transistor, such that the drain of the respective second MOSFET transistor and the gate of the first MOSFET transistor are at equal potential.
  • In one embodiment, the source of said one of the second MOSFET transistors is connected to the drain of the first MOSFET transistor. The source of the first MOSFET transistor is connected for example to ground, or may be connected to a voltage source or another MOSFET transistor in order to provide for a voltage shift at the source of the first MOSFET transistor. The first MOSFET transistor hence is arranged in between the source of the respective one of the second MOSFET transistors and ground (or a voltage source or another MOSFET transistor in the path towards ground).
  • In one embodiment, the drain and the gate of the other of the second MOSFET transistors are connected to each other. The drain and the gate of the other of the second MOSFET transistors hence are short-circuited and are at the same potential. The second MOSFET transistors together provide for the voltage corresponding to a difference voltage (delta voltage) in between the sources of the two second MOSFET transistors. Said voltage can be the output voltage, or generating the output voltage with other voltage sources or another MOSFET transistor in the path toward ground.
  • In one embodiment, the first circuit portion comprises a pair of third MOSFET transistors. The gates of the third MOSFET transistors are connected to each other, such that the gates of the third MOSFET transistors are at equal potential.
  • In one embodiment, the third MOSFET transistors are configured to operate in a weak inversion region of MOSFET operation. For this, the first circuit portion is operated such that the gate-source voltage of both of the third MOSFET transistors is smaller than a threshold voltage associated with the respective MOSFET transistor. In order to ensure an operation in the weak inversion region, the third MOSFET transistors may for example be dimensioned large, i.e. to comprise a comparatively large channel width and length.
  • In one embodiment, the first circuit portion comprises a pair of fourth MOSFET transistors connected at their gates and serving as a current mirror. The pair of fourth MOSFET transistors is connected to the pair of third MOSFET transistors such that a drain of each of the fourth MOSFET transistors is connected to a drain of one of the third MOSFET transistors. In that the pair of fourth MOSFET transistors functions as a current mirror, an equal current is passed through the pair of third MOSFET transistors.
  • According to an embodiment, the pair of fourth MOSFET transistors are p-type MOSFET transistors, or PMOS transistors, wherein the pair of first, second and third MOSFET transistors are NMOS transistors. The pair of fourth MOSFET transistors have the source on the Vcc side. The voltages from source to drain and from source to gate are of positive polarity.
  • According to an embodiment, the drain of one of the MOSFET transistors from the pair of fourth MOSFET transistors and the connected drain of one of the third MOSFET transistors are connected to a third circuit portion. The third circuit portion comprises a pair of fifth MOSFET transistors connected at their gates and serving as a current mirror. In that the pair of fifth MOSFET transistors functions as a current mirror, an equal current, for instance a reference current IREF, is passed through the pair of fifth MOSFET transistors.
  • According to an embodiment, the pair of fifth MOSFET transistors are PMOS transistors, having the source on the Vcc side. The voltages from source to drain and from source to gate are of positive polarity.
  • In one embodiment, the MOSFET transistors of the pair of fifth MOSFET transistors are dimensioned with equal channel width W divided by channel length L, as the W/L of one MOSFET transistor of the pair of fourth MOSFET transistors.
  • In one embodiment, one of the third MOSFET transistors at its source is connected to a non-temperature-dependent resistance. The first circuit portion is configured to output the reference current according to a reference voltage produced across the non-temperature-dependent resistance. The reference voltage is produced as a difference voltage (delta voltage) between the pair of third MOSFET transistors and comprises a temperature dependency in accordance with the temperature dependency of the third MOSFET transistors. In that the reference voltage is applied across the non-temperature-dependent reference resistance, the reference current results which exhibits a temperature dependency according to the temperature dependency of operation of the third MOSFET transistors.
  • Whereas the temperature dependency of the first circuit portion for providing the temperature-dependent reference current is largely governed by the pair of third MOSFET transistors, the temperature dependency of the second circuit portion for providing the temperature-dependent output voltage is largely governed by the pair of second MOSFET transistors. By suitably choosing the third MOSFET transistors and the second MOSFET transistors, thus, a substantially equal temperature dependency of both the first circuit portion and the second portion may be achieved, such that a temperature compensation may be obtained by a cancellation of the temperature dependency of the reference current and the temperature dependency of the output voltage.
  • In one embodiment, the gate of the first MOSFET transistor is connected to a gate of a target (MOSFET) transistor to produce a temperature-independent ON resistance at the target transistor. The first MOSFET transistor in particular may function as a reference to control any target MOSFET transistor to obtain a substantially constant (temperature-independent) ON resistance. By connecting one or multiple target transistors to the first MOSFET transistor, a controlling of the gate of multiple target transistors may be established for controlling the ON resistance of the target transistors to be substantially temperature-independent.
  • In one embodiment, an implantable medical device for performing a therapeutic and/or diagnostic function in a patient comprises a circuit arrangement of the kind described above. The implantable medical device in particular may be a stimulation device, such as a cardiac stimulation device or a neuro-stimulation device. For example, the implantable medical device may be a cardiac pacemaker device or a cardiac defibrillator device, such as a CRT device or an ICD device. In other embodiments, the implantable medical device may for example be an implantable sensor device or an implantable monitoring device.
  • The various features and advantages of the present invention may be more readily understood with reference to the following detailed description and the embodiments shown in the drawings. Herein,
  • Fig. 1
    shows a schematic drawing of a system comprising an implantable medical device implanted in a patient;
    Fig. 2
    shows a circuit schematic of a circuit arrangement for providing a temperature-compensated output resistance at a target transistor;
    Fig. 3
    shows a circuit schematic of a first circuit portion of the circuit arrangement for providing a temperature-dependent reference current;
    Fig. 4
    shows a circuit schematic of another embodiment of a circuit arrangement for providing a temperature-compensated output resistance;
    Fig. 5
    shows a circuit schematic of yet another embodiment of a circuit arrangement for providing a temperature-compensated output resistance;
    Fig. 6
    shows an output characteristic of a MOSFET device; and
    Fig. 7
    shows a characteristic indicating the three regions of operation of a MOSFET transistor.
  • Subsequently, embodiments of the invention shall be described in detail with reference to the drawings. In the drawings, like reference numerals designate like structural elements.
  • It is to be noted that the embodiments are not limiting for the invention, but merely represent illustrative examples.
  • Referring to Fig. 1, in one embodiment a system comprises an implantable medical device 1 implanted into a patient for serving a therapeutic cardiac stimulation function. The implantable medical device 1, in the shown embodiment, comprises a generator device 10 and an arrangement of electrode leads 11, 12, 13 extending from the generator device 10. The generator device 10 may for example be implanted subcutaneously into a patient P, the electrode leads 11, 12, 13 reaching into the patient's heart for monitoring cardiac activity of the patient's heart.
  • The generator device 10 comprises a processing circuitry 14 encapsulated in a housing of the generator device 10 together with an electrochemical battery for supplying electrical energy for operation of the implantable medical device 1.
  • The system furthermore comprises an external device 2 external to the patient P and being in communication connection with the implantable medical device 1. The external device 2 may be in connection, via a public communication network 4, with a remote server device 3, for example a home monitoring service center (HMSC) accessible by a physician, in the context of a home monitoring system. According to an embodiment, another type of external device (not depicted) is used to communicate with the implantable medical device 1 using a first communication coil in the external device and a second communication coil in the implantable medical device. The external device is brought in proximity (about 10 cm) to the implantable medical device 1 to achieve inductive coupling between the two coils, enabling data exchange. The receiver circuit in the implantable medical device 1 for said coil communication is limited in space and area, and exposed to temperature variations. Using the circuit arrangement(s) of the present invention, resistances can be generated which are constant in regard to with temperature changes and processing variations. The described circuit arrangement(s) can be used for telemetry integrated circuits of implantable medical device 1.
  • Generally, the processing circuitry 14 is configured for providing a therapeutic and/or diagnostic function using the implantable medical device 1. In addition, the processing circuitry 14 may be embodied to establish a communication connection to an external device 2 and for this may comprise circuitry in order to establish a communication for example using RF signals.
  • The implantable medical device 1, for example a cardiac stimulation device such as a pacemaker device or a defibrillator device, for example a CRT device or an ICD device, generally shall be designed such that it may rest within a patient P over a prolonged duration of time, making it necessary for the implantable medical device 1 to function in an energy-efficient manner by using energy resources of a battery encapsulated within a housing of the implantable medical device 1. As severe space restrictions exist for components of the implantable medical device 1, including the processing circuitry 14 and the battery, it is important to design the implantable medical device 1 with components allowing for a space-efficient implementation of the implantable medical device 1 and at the same time for a power-efficient operation of the implantable medical device 1 over its lifetime.
  • The processing circuitry 14 generally, in order to provide for a power-efficient operation and space-efficient structure, is designed using CMOS analog circuit design. In particular, components of the processing circuitry 14, such as resistances or inductances, may be modeled using arrangements of MOSFET transistors.
  • Referring now to Fig. 2, in one embodiment a circuit arrangement 140 of the processing circuitry 14 is configured for setting an output resistance at the target transistor M4. The output resistance is set at the target transistor M4 by controlling the gate voltage at the gate G of the target transistor M4 and shall be such that it is substantially temperature independent in order to provide for a temperature-stable resistance.
  • Resistances in the processing circuitry 14 may serve different purposes. For example, a resistance may be combined in a communication circuitry with a capacitance in order to provide for a filtering circuit to tune the communication circuitry to a desired frequency band of communication. For this, a temperature-stable operation is desired to allow for a stable communication in a specific, for example narrow frequency band, taking into account that within a patient P temperature conditions are substantially different than outside of the patient P and in addition may vary over time.
  • Using the circuit arrangement 140 according to Fig. 2, a temperature-compensated output resistance is set at a MOSFET transistor M3 and also at the target transistor M4 by controlling the gate voltage at the gate G of the target transistor M4 using the MOSFET transistor M3.
  • Namely, the circuit arrangement 140 according to Fig. 2 comprises a first circuit portion configured for delivering a reference current IREF , denoted in Fig. 2 by current sources and shown in an embodiment in Fig. 3.
  • In addition, the circuit arrangement 140 according to Fig. 2 comprises a second circuit portion made up of MOSFET transistors M1, M2, which are fed at their drains D with the reference current IREF and are connected to one another at their gates G. One of the MOSFET transistors M1, M2 - in the example of Fig. 2 the MOSFET transistor M2 - at its source S is connected to the drain D of the MOSFET transistor M3. In addition, the drain D of the MOSFET transistor M2 is connected to the gate G of the MOSFET transistor M3, such that the gate voltage Vgate of the MOSFET transistor M3 is drawn to the high-ohmic drain D of the MOSFET transistor M2. Further, the drain D of the MOSFET transistor M1 is connected (short-circuited) to its gate G.
  • Generally, any MOSFET transistor as concerned herein comprises a drain D, a source S and a gate G as well-known in the art and as typical for a MOSFET transistor.
  • Using the second circuit portion comprising the MOSFET transistors M1, M2, an output voltage VR is applied across the drain D and the source S of the MOSFET transistor M3, as it is indicated in Fig. 2. The output voltage VR herein is provided as a difference voltage (delta voltage) in between the sources S of the MOSFET transistors M1, M2.
  • The MOSFET transistors M1, M2 operate in a weak inversion region of MOSFET operation. As it is well-known in MOSFET technology, in the weak inversion region WI as illustrated in the characteristic of Fig. 7 the gate-source voltage is below a threshold voltage (generally denoted as VT in the literature), whereas in contrast in a strong inversion region SI, separated from the weak inversion region WI by a moderate inversion region MI, the gate-source voltage is above the threshold voltage. This is described in detail e.g. in the textbook by Phillip E. Allen and Douglas R. Holberg, "CMOS analog circuit design", 1987, ISBN 0-19-510720-9.
  • The MOSFET transistor M3, in turn, operates in the linear region, in which the drain-source voltage is below a saturation voltage, as it is indicated in Fig. 6 and as it is commonly known in MOSFET technology.
  • The output voltage VR for the MOSFET transistors M1, M2 operating in the weak inversion region can be computed as follows: V R = V Temp ln Y where VTemp is a temperature voltage equal to V Temp = k B T e 26.7 mV at 37 ° C (kB : Boltzmann constant; T: absolute temperature in Kelvin; e: elementary charge) and Y is a factor computed according to the ratio of channel width W and channel length L of the two MOSFET transistors M1, M2 as follows: Y = W L M 2 W L M 1
  • The output resistance at the MOSFET transistor M3 corresponds to the ON resistance RON,M3 = RDS,M3 of the MOSFET transistor M3, which is computed as follows: R DS , M 3 = R ON , M 3 = V R I REF
  • As visible from equation (1) above, the output voltage VR comprises a temperature dependency according to the temperature voltage VTemp. In addition, in the circuit arrangement 140 according to Fig. 2 the reference current IREF is provided to comprise a temperature dependency which at least is similar to the temperature dependency of the output voltage VR, such that according to equation (4) the temperature dependencies cancel each other out, and a substantially constant output resistance R ON, M3 RDS,M3 results.
  • In one embodiment, the reference current IREF is provided by a circuit portion 141 as illustrated in the circuit schematic of Fig. 3.
  • The circuit portion 141 according to Fig. 3 comprises a pair of MOSFET transistors M5, M6, which are connected to each other at their gates G. A pair of further MOSFET transistors M7, M8, which are PMOS transistors, have the source on the Vcc side. The voltages from source to drain and from source to gate are of positive polarity. M7, M8 function as a current mirror and is formed equal, the MOSFET transistors M7, M8 being connected at their sources S to a supply voltage VCC and at their drains D to the drains D of the MOSFET transistors M5, M6, as this is shown in Fig. 3. The gate G of the MOSFET transistor M8 herein is connected (short-circuited) to its drain D. The drain D of the MOSFET transistor M5 is connected (short-circuited) to its gate G.
  • According to an embodiment, the drain of M8 and the drain of connected M6 are connected to another circuit portion 144. The circuit portion 144 comprises a pair of MOSFET transistors M11, M12 which are connected at their gates and serving as a current mirror. In that the pair of MOSFET transistors M11, M12 functions as a current mirror, an equal current, for instance a reference current IREF, is passed through the pair of MOSFET transistors M11, M12.
  • According to an embodiment, the pair of MOSFET transistors M11, M12 are PMOS transistors, having the source on the Vcc side. The voltages from source to drain and from source to gate are of positive polarity.
  • In one embodiment, the MOSFET transistors of M11, M12 are dimensioned with equal channel width W divided by channel length L, as the W/L of one MOSFET transistors M8 or M9, for example M8.
  • In that the MOSFET transistors M7, M8 function as a current mirror with factor 1:1 or other factors, they impose an identical reference current IREF through the MOSFET transistors M5, M6, such that the drain currents of both MOSFET transistors M5, M6 are equal and correspond to the reference current IREF .
  • The MOSFET transistor M6 at its source S is connected to a reference resistance RREF which comprises a substantially temperature-independent, constant resistance.
  • The MOSFET transistors M5, M6 both operate in the weak inversion region.
  • The reference voltage VREF across the reference resistance RREF is computed as follows: V REF = V Temp ln I D , M 5 I D , M 6 X where VTemp again is the temperature voltage, and X is a factor according to X = W L M 6 W L M 5 W, L represent the channel width and the channel length of the respective transistor M5, M6, such that the factor X expresses the ratio of channel width and channel length of the two transistors M5, M6.
  • As the current through the MOSFET transistors M5, M6 is equal (ID,M5 = ID,M6 ) and corresponds to the reference current IREF imposed by the current mirror of the pair of MOSFET transistors M7, M8, the reference voltage becomes V REF = V Temp ln X and the reference current is I REF = V REF R REF = V Temp R REF ln X
  • When applying equation (8) to equation (4), the output resistance corresponding to the ON resistance of the MOSFET transistor M3 in the circuit arrangement 140 of Fig. 2 becomes, when assuming a linear characteristic curve, R DS , M 3 = R ON , M 3 = V REF I REF = R REF ln Y ln X
  • More exact, the output resistance corresponding to the ON resistance of the MOSFET transistor M3 becomes R DS , M 3 = R ON , M 3 = V REF I REF = R REF Y 1 ln X
  • In both equations (9) and (10) the output resistance is temperature-compensated, in that the temperature dependencies of the output voltage VR and the reference current IREF cancel out.
  • In particular, the gate voltage of the MOSFET transistor M3 will regulate itself according to the output voltage VR and the imposed reference current IREF such that an output resistance, corresponding to the drain-source resistance, results which fulfills the equation (4) above.
  • If the output voltage VR and the reference current IREF have the same temperature characteristic, the temperature dependencies cancel each other out, such that a substantially temperature-independent output resistance at the MOSFET transistor M3 results.
  • If in addition the output voltage VR and the reference current IREF have an equal or no process dependency, the output resistance in addition is independent in this respect.
  • The gate voltage of the MOSFET transistor M3 serves as a reference voltage for the target transistor M4 and potential further MOSFET transistors, which shall exhibit a defined, temperature-compensated ON resistance. The controlled gate voltage of the MOSFET transistor M3 thus provides for a compensation of temperature variations in the target transistors M4.
  • An adaption of a resistance value may be provided by adjusting the transistor geometry of the respective target transistor M4, wherein the output resistance (ON resistance) is indirectly proportional to the ratio of channel width and channel length.
  • According to an embodiment, M1, M2 M5 and M6 are in weak inversion region and in saturation. According to an embodiment, M7, M8 and IREF are saturated, wherein M7 and M8 may be in weak inversion, strong inversion or moderate inversion region.
  • According to an embodiment, M3 should be dimensioned so that M2 operates in saturated mode over the entire target temperature range and the IREF current source is not affected (i.e. the IREF transistor always remains saturated). In detail, this means that the gate voltage is always above Vgate,min (M2) and below Vgate,max (IREF transistor). At M1, saturation is inherently ensured by the Gate-Drain connection. The same applies to M5/M6 and M7/M8. Saturated operation should be ensured for all of them.
  • A small error may result in case a current flow through the transistors M3 and M4 differs and due to the exponential characteristic of the ON resistance (see Fig. 6).
  • At the target transistor M4 the bias current/voltage is approximately 0 and the ON resistance in effect acts only dynamically. An improved operation may be possible by separating the transistors M3 and M4 into multiple serially connected MOSFET transistors of equal size, such that the output voltage VR is equally distributed across the serially connected MOSFET transistors.
  • Referring now to Fig. 4, in another embodiment of a circuit arrangement 142 the MOSFET transistor M3 is not connected directly to ground, but in addition a voltage source V1 is arranged in the path between the source S of the MOSFET transistor M3 towards ground. In this way a voltage shift by the voltage V1 may be obtained.
  • Other than that, the circuit arrangement 142 of Fig. 4 is functionally identical to the circuit arrangement 140 of Fig. 2.
  • Referring now to Fig. 5, in an embodiment of a circuit arrangement 143 to implement a voltage shift as illustrated in Fig. 4, for example a MOSFET transistor M9 may be connected in between the source S of the MOSFET transistor M3 and ground, as illustrated in Fig. 5. In addition, a MOSFET transistor M10 may be connected in between the source S of the MOSFET transistor M4 and ground. The voltage V2 across the MOSFET transistor M9 may be set equal to the voltage V1 between the source S of the MOSFET transistor M4 and ground by suitably designing the drain current of the MOSFET transistor M10 and the channel width and channel length of the MOSFET transistor M9.
  • Other than the arrangement of transistors M9, M10, the circuit arrangement 143 of Fig. 5 is functionally identical to the circuit arrangement 140 of Fig. 2.
  • The MOSFET transistors M1, M2 in the circuit arrangement 140 of Fig. 2 and likewise in the circuit arrangement 142 of Fig. 4 and the circuit arrangement 143 of Fig. 5 may also be implemented by bipolar transistors.
  • The reference current IREF may generally lie in a range between 10 nA and 100 nA, for example at around 20 nA.
  • The output voltage VR may generally lie in a range between 35 mV to 60 mV.
  • The ON resistance of the MOSFET transistor M3 may for example have a resistance value in between 500 kOhm to 6 MOhm, wherein the ON resistance of the MOSFET transistor M4 may have a scaling factor from 1 to 100 compared to the resistance of M3, which is resistance value in between 500 kOhm to 600 MOhm.
  • The idea underlying the invention is not limited to the embodiments described above, but may be implemented in an entirely different fashion.
  • The implantable medical device may be for example an ICD or a CRT-D device or another pacemaker device.
  • The implantable medical device may comprise electrode leads carrying electrode poles, which may be implanted to reach into the patient's heart, or may rest fully outside of the patient's heart when they are implanted in the patient. In other embodiments, the implantable medical device is a leadless device not comprising electrode leads.
  • List of reference numerals
  • 1
    Implantable medical device
    10
    Generator
    11
    Electrode lead
    12
    Electrode lead
    13
    Electrode lead
    14
    Processing circuitry
    140-144
    Circuit arrangement /circuit portion
    2
    External device
    3
    Remote server device
    4
    Public communication network
    D
    Drain of MOSFET transistor
    G
    Gate of MOSFET transistor
    ID, M10
    Drain current through transistor M10
    IREF
    Reference current
    LR
    Linear region
    M1-M12
    MOSFET transistor
    MI
    Moderate inversion region
    P
    Patient
    RREF
    Non-temperature-dependent resistance
    S
    Source of MOSFET transistor
    SI
    Strong inversion region
    V1, V2
    Voltage
    VCC
    Supply voltage
    VGate
    Gate voltage
    VR
    Output voltage
    VREF
    Reference voltage
    WI
    Weak inversion region
    X, Y
    Factor

Claims (15)

  1. Circuit arrangement (140-144) for use in an implantable medical device (1), configured for providing a temperature-compensated output resistance, comprising:
    a first MOSFET transistor (M3),
    a first circuit portion configured to supply a temperature-dependent reference current (IREF) to the first MOSFET transistor (M3), and
    a second circuit portion configured to generate a temperature-dependent output voltage (VR) across a drain (D) and a source (S) of the first MOSFET transistor (M3), such that an ON resistance (RON,M3) of the first MOSFET transistor (M3) resulting from the output voltage (VR) and the reference current (IREF) provides the temperature-compensated output resistance.
  2. Circuit arrangement (140-144) according to claim 1, wherein the first MOSFET transistor (M3) is configured to operate in a linear region of MOSFET operation.
  3. Circuit arrangement (140-144) according to claim 1 or 2, wherein the temperature-dependent reference current (IREF) comprises a first temperature dependency and the temperature-dependent output voltage (VR) comprises a second temperature dependency, wherein the first temperature dependency and the second temperature dependency are at least approximately equal.
  4. Circuit arrangement (140-144) according to one of the preceding claims, wherein the second circuit portion comprises a pair of second MOSFET transistors (M1, M2), wherein gates (G) of the second MOSFET transistors (M1, M2) are connected to each other.
  5. Circuit arrangement (140-144) according to claim 4, wherein the second MOSFET transistors (M1, M2) are configured to operate in a weak inversion region of MOSFET operation.
  6. Circuit arrangement (140-144) according to claim 4 or 5, wherein the first circuit portion is connected to drains (D) of the second MOSFET transistors (M1, M2) to supply the reference current (IREF) to the drains (D) of the second MOSFET transistors (M1, M2).
  7. Circuit arrangement (140-144) according to one of claims 4 to 6, wherein the drain (D) of one of the second MOSFET transistors (M1, M2) is connected to a gate (G) of the first MOSFET transistor (M3).
  8. Circuit arrangement (140-144) according to claim 7, wherein the source (S) of said one of the second MOSFET transistors (M1, M2) is connected to the drain (D) of the first MOSFET transistor (M3).
  9. Circuit arrangement (140-144) according to one of claims 4 to 8, wherein the drain (D) and the gate (G) of the other of the second MOSFET transistors (M1, M2) are connected to each other.
  10. Circuit arrangement (140-144) according to one of the preceding claims, wherein the first circuit portion comprises a pair of third MOSFET transistors (M5, M6), wherein gates (G) of the third MOSFET transistors (M5, M6) are connected to each other.
  11. Circuit arrangement (140-144) according to claim 10, wherein the third MOSFET transistors (M5, M6) are configured to operate in a weak inversion region of MOSFET operation.
  12. Circuit arrangement (140-144) according to claim 10 or 11, wherein the first circuit portion comprises a pair of fourth MOSFET transistors (M7, M8) connected at their gates (G) and serving as a current mirror, wherein a drain (D) of each of the fourth p-type MOSFET transistors (M7, M8) is connected to a drain (D) of one of the third MOSFET transistors (M5, M6).
  13. Circuit arrangement (140-144) according to one of claims 10 to 12, wherein one of the third MOSFET transistors (M5, M6) at its source (S) is connected to a non-temperature-dependent resistance (RREF), wherein the first circuit portion is configured to output said reference current (IREF) according to a reference voltage (VREF) produced across said non-temperature-dependent resistance (RREF).
  14. Circuit arrangement (140-144) according to one of the preceding claims, wherein the gate (G) of the first MOSFET transistor (M3) is connected to a gate (G) of a target transistor (M4) to produce a temperature-independent ON resistance at the target transistor (M4).
  15. Implantable medical device (1) for performing a therapeutic and/or diagnostic function in a patient (P), comprising a circuit arrangement (140-144) according to one of the preceding claims.
EP24188848.6A 2024-07-16 2024-07-16 Circuit arrangement for use in an implantable medical device Pending EP4682670A1 (en)

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EP24188848.6A EP4682670A1 (en) 2024-07-16 2024-07-16 Circuit arrangement for use in an implantable medical device

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Application Number Priority Date Filing Date Title
EP24188848.6A EP4682670A1 (en) 2024-07-16 2024-07-16 Circuit arrangement for use in an implantable medical device

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EP4682670A1 true EP4682670A1 (en) 2026-01-21

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120274306A1 (en) * 2009-03-31 2012-11-01 Analog Devices, Inc. Method and circuit for low power voltage reference and bias current generator
EP3210215B1 (en) * 2014-10-22 2024-03-06 Murata Manufacturing Co., Ltd. Pseudo resistance circuit and charge detection circuit

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120274306A1 (en) * 2009-03-31 2012-11-01 Analog Devices, Inc. Method and circuit for low power voltage reference and bias current generator
EP3210215B1 (en) * 2014-10-22 2024-03-06 Murata Manufacturing Co., Ltd. Pseudo resistance circuit and charge detection circuit

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PHILLIP E. ALLENDOUGLAS R. HOLBERG: "CMOS analog circuit design", 1987
ZHANG TAN-TAN ET AL: "A BJT-Based Temperature Sensor in 40-nm CMOS With 0.8°C(3[sigma]) Untrimmed Inaccuracy", 2019 32ND IEEE INTERNATIONAL SYSTEM-ON-CHIP CONFERENCE (SOCC), IEEE, 3 September 2019 (2019-09-03), pages 1 - 4, XP033768815, DOI: 10.1109/SOCC46988.2019.1570555725 *

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