EP4110439A1 - Syringe with brake means - Google Patents
Syringe with brake meansInfo
- Publication number
- EP4110439A1 EP4110439A1 EP21707626.4A EP21707626A EP4110439A1 EP 4110439 A1 EP4110439 A1 EP 4110439A1 EP 21707626 A EP21707626 A EP 21707626A EP 4110439 A1 EP4110439 A1 EP 4110439A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- syringe
- piston
- barrel
- brake means
- stroke
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M2005/3151—Means for blocking or restricting the movement of the rod or piston by friction
Definitions
- the present invention relates generally to syringe and particularly, although not exclusively, to a syringe of the type comprising a tube/barrel/body and a plunger/piston.
- a syringe is a simple reciprocating pump consisting of a plunger/piston that fits tightly within a cylindrical tube (often called a barrel).
- the plunger can be linearly pulled and pushed along the inside of the tube, allowing the syringe to take in and expel liquid or gas through a discharge orifice at a front end of the tube.
- Figure I and 2 illustrate analysis of a syringe 10 conducted by the present inventors. It appears that, with constant pressure, the speed of the piston 20 within the barrel 30 accelerates at the end of the stroke (indicated by box B) compared to the initial part of the stroke (illustrated by box A) due to a different tightening between the piston and body in these areas. This can result in a “spray effect” at the end of the stroke.
- the present invention seeks to provide improvements in or relating to syringes.
- An aspect of the present invention provides a syringe comprising a barrel having an outlet and a piston movable along the inside of the barrel to take in or expel fluid from the outlet, the syringe comprising brake means for influencing movement of the piston.
- the goal of some embodiments is to reduce/eliminate the spray effect at the end of use.
- the brake means may be effective to slow insertion of the piston over at least part of the stroke.
- the brake means may be effective to slow insertion of the piston over only part of the stroke.
- the brake means may slow the piston as it approaches the end of the insertion stroke.
- the brake mean may be effective to decelerate insertion of the piston towards the end of the stroke; for example during the final approximately 1%, 5%, 10%, 15%, 20%, 25% or 30% of the stroke.
- Brake means may be provided on or by the piston. Alternatively or additionally brake means may be provided on or by the barrel.
- Brake means may be provided at or towards an end of the piston distal to the barrel outlet.
- the brake means may comprise friction means.
- the brake means may comprise one or more friction elements, for example ribs, strips, bumps, pads, stickers, roughened zones, interference zones, higher friction zones or the like.
- the friction element/s may, for example, comprise one or more longitudinal elongate (for example generally oval) increased friction zones/areas.
- the outlet end of the barrel is generally flat. In other embodiments the barrel may comprises a nozzle.
- the open end of the syringe may, for example, be fitted with a hypodermic needle, a nozzle or tubing to direct the flow into and out of the barrel.
- the barrel and/or the piston may be generally cylindrical with a generally circular section.
- the outlet may be located generally centrally. Alternatively the outlet may be located eccentrically.
- a further aspect provides a syringe comprising a body and a sliding plunger, the plunger can be linearly moved inside of the body in a pull stroke and a push stroke to draw in or expel liquid from a discharge orifice the body, in which the syringe comprises a friction zone for increasing interference between the plunger and the body to slow down acceleration of the piston towards the end of the push stroke whereby to avoid a spray effect.
- the body may be a cylindrical tube or barrel.
- the syringe may comprise a cylindrical friction area that is active in the few last millimetres of the insertion stroke.
- the friction area may be made up of cylindrical area on the body and bump/s or cylindrical ring/s on the plunger, the interference between these two surfaces brakes the advance of the piston to compensate the acceleration in end of use.
- the friction area may be an integral part of the piston/body, or it may be formed separately. A bi-injection process, for example, would allow different materials to be used, with a higher friction material used for brake element/s.
- the friction zone may be raised from the surface of the piston and/or barrel, or it may be flush. Alternatively of additionally increased friction may be provided by texture (e.g. roughened) and/or surface formations.
- the friction element/s may be formed from the same or a different material to the barrel/piston.
- a further aspect provides a syringe piston with a brake.
- the syringe may be a reciprocating pump in which a sliding piston fits tightly within a barrel (cylindrical tube).
- the barrel may have a terminal flange at one (open) end and a central outlet at the other (flat) end.
- the piston may also have a corresponding terminal flange.
- the measured capacity of the barrel may be 5ml.
- the brake may, for example, be active during the final (approximately) I ml of the stroke.
- a “bumper” / ’’brake” / ’’deceleration” zone may be added to the piston and may be effective at the end of the insertion/dispensing stroke. With small interference with the barrel, it may brake the piston without stopping the stroke, and then avoid the “spray effect”.
- the brake may be provided by a plurality of mutually spaced, elongate oval friction elements that are circumferentially distributed and extend longitudinally along the exterior surface of the piston.
- Functionality of the syringe may include or be based on: with the piston withdrawn or partially withdrawn this is before the brake is active; the piston is inserted further and just in advance of the brake zone entering the interior of the barrel; the brake zone enters the interior of the barrel to start increasing interference between the piston and the barrel (this may be immediately or maybe (somewhat/slightly) distal to the flange end of the barrel); the piston is fully inserted; the brake zone is frictionally engaged within the interior of the barrel.
- the syringe piston may provide a brake function.
- the syringe may provide a cylindrical friction area that may be active in the few last millimetre of the stroke. It may be made up of a cylindrical area (which may be generally smooth) on the barrel and bumps (or a cylindrical ring, for example) on the piston. The interference between these two surfaces may brake the advance of the piston to compensate the acceleration in end of use.
- FIG. 3 shows a syringe I 10 formed in accordance with the present invention.
- the syringe is a reciprocating pump in which a sliding piston 120 fits tightly within a barrel 130 (cylindrical tube).
- the barrel 130 has a terminal flange 132 at one (open) end and a central outlet 134 at the other (flat) end.
- the piston 120 also has a corresponding terminal flange 122.
- the measured capacity of the barrel is 5ml.
- the brake is active during the final (approximately) I ml of the stroke.
- a “bumper” / ’’brake” / ’’deceleration” zone 140 is added to the piston and is effective at the end of the insertion/dispensing stroke. With small interference with the barrel, it will brake the piston without stopping the stroke, and then avoid the “spray effect”.
- the brake is provided by a plurality of mutually spaced, elongate oval friction elements 150 that are circumferentially distributed and extend longitudinally along the exterior surface of the piston.
- Figures 4 to 6 illustrate the functionality of the syringe I 10.
- Figure 4 shows the piston 120 partially withdrawn and before the brake is active.
- Figure 5 shows the piston inserted further and just in advance of the brake zone 140 entering the interior of the barrel 130 to start increasing interference between the piston and the barrel.
- Figure 6 shows the piston fully inserted; the brake zone is shown to be frictionally engaged with the interior of the barrel. Movement from Figure 4 to Figure 5 is unaffected; movement from Figure 5 to Figure 6 is under the influence of increased interference to decelerate the piston.
- Figures 7 to 9 show a syringe 210 formed in accordance with a further embodiment.
- the syringe piston provides a brake function. In the absence of a brake there would be an acceleration of the piston in the few last millimetre stroke, which can cause a risk of suffocation. This acceleration is due to a difference in interference between the barrel and the piston head 224 over the length of the barrel and the position at the very end of injection. To reduce this phenomenon, the syringe 210 provides a cylindrical friction area 240 that must be active in the few last millimetre of the stroke. It is made up of a cylindrical area (which may be generally smooth) on the barrel and bumps 250 (or a cylindrical ring, for example) on the piston 220. The interference between these two surfaces brakes the advance of the piston to compensate the acceleration in end of use.
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP25212878.0A EP4684820A3 (en) | 2020-02-27 | 2021-02-10 | Syringe |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2002791.8A GB202002791D0 (en) | 2020-02-27 | 2020-02-27 | Syringe |
| PCT/EP2021/053123 WO2021170401A1 (en) | 2020-02-27 | 2021-02-10 | Syringe with brake means |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP25212878.0A Division EP4684820A3 (en) | 2020-02-27 | 2021-02-10 | Syringe |
| EP25212878.0A Division-Into EP4684820A3 (en) | 2020-02-27 | 2021-02-10 | Syringe |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP4110439A1 true EP4110439A1 (en) | 2023-01-04 |
| EP4110439C0 EP4110439C0 (en) | 2025-12-24 |
| EP4110439B1 EP4110439B1 (en) | 2025-12-24 |
Family
ID=70278681
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP25212878.0A Pending EP4684820A3 (en) | 2020-02-27 | 2021-02-10 | Syringe |
| EP21707626.4A Active EP4110439B1 (en) | 2020-02-27 | 2021-02-10 | Syringe with brake means |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP25212878.0A Pending EP4684820A3 (en) | 2020-02-27 | 2021-02-10 | Syringe |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230158245A1 (en) |
| EP (2) | EP4684820A3 (en) |
| CN (1) | CN115175717A (en) |
| GB (1) | GB202002791D0 (en) |
| WO (1) | WO2021170401A1 (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2037768A (en) * | 1931-11-13 | 1936-04-21 | Fairleigh S Dickinson | Syringe |
| US2703575A (en) * | 1952-07-18 | 1955-03-08 | Chibret Rene | Hypodermic syringe made of plastic material |
| EP3602528B1 (en) * | 2017-03-29 | 2023-09-27 | Noble International, Inc. | Prefilled syringe plunger simulation training device |
-
2020
- 2020-02-27 GB GBGB2002791.8A patent/GB202002791D0/en not_active Ceased
-
2021
- 2021-02-10 CN CN202180017072.5A patent/CN115175717A/en active Pending
- 2021-02-10 EP EP25212878.0A patent/EP4684820A3/en active Pending
- 2021-02-10 US US17/801,662 patent/US20230158245A1/en active Pending
- 2021-02-10 EP EP21707626.4A patent/EP4110439B1/en active Active
- 2021-02-10 WO PCT/EP2021/053123 patent/WO2021170401A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP4684820A2 (en) | 2026-01-28 |
| WO2021170401A1 (en) | 2021-09-02 |
| GB202002791D0 (en) | 2020-04-15 |
| EP4684820A3 (en) | 2026-03-25 |
| CN115175717A (en) | 2022-10-11 |
| US20230158245A1 (en) | 2023-05-25 |
| EP4110439C0 (en) | 2025-12-24 |
| EP4110439B1 (en) | 2025-12-24 |
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