EP4103579A4 - Novel triterpene derivatives as hiv inhibitors - Google Patents

Novel triterpene derivatives as hiv inhibitors Download PDF

Info

Publication number
EP4103579A4
EP4103579A4 EP21753151.6A EP21753151A EP4103579A4 EP 4103579 A4 EP4103579 A4 EP 4103579A4 EP 21753151 A EP21753151 A EP 21753151A EP 4103579 A4 EP4103579 A4 EP 4103579A4
Authority
EP
European Patent Office
Prior art keywords
hiv inhibitors
triterpene derivatives
novel triterpene
novel
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21753151.6A
Other languages
German (de)
French (fr)
Other versions
EP4103579A1 (en
Inventor
Parthasaradhi Reddy BANDI
Rathnakar Reddy KURA
Panduranga Reddy ADULLA
Bhaskar Reddy KASIREDDY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hetero Labs Ltd
Original Assignee
Hetero Labs Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hetero Labs Ltd filed Critical Hetero Labs Ltd
Publication of EP4103579A1 publication Critical patent/EP4103579A1/en
Publication of EP4103579A4 publication Critical patent/EP4103579A4/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP21753151.6A 2020-02-11 2021-02-11 Novel triterpene derivatives as hiv inhibitors Pending EP4103579A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN202041005909 2020-02-11
PCT/IB2021/051116 WO2021161206A1 (en) 2020-02-11 2021-02-11 Novel triterpene derivatives as hiv inhibitors

Publications (2)

Publication Number Publication Date
EP4103579A1 EP4103579A1 (en) 2022-12-21
EP4103579A4 true EP4103579A4 (en) 2024-05-01

Family

ID=77292985

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21753151.6A Pending EP4103579A4 (en) 2020-02-11 2021-02-11 Novel triterpene derivatives as hiv inhibitors

Country Status (6)

Country Link
US (1) US20230174570A1 (en)
EP (1) EP4103579A4 (en)
JP (1) JP2023513331A (en)
CN (1) CN115380040A (en)
WO (1) WO2021161206A1 (en)
ZA (1) ZA202209130B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020165741A1 (en) * 2019-02-11 2020-08-20 Hetero Labs Limited Novel triterpene derivatives as hiv inhibitors

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130072465A1 (en) * 2011-09-21 2013-03-21 Bristol-Myers Squibb Company Novel betulinic acid derivatives with antiviral activity
WO2017149518A1 (en) * 2016-03-04 2017-09-08 Hetero Labs Limited C-3 novel triterpene with c-17 amine derivatives as hiv inhibitors
WO2020165741A1 (en) * 2019-02-11 2020-08-20 Hetero Labs Limited Novel triterpene derivatives as hiv inhibitors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130072465A1 (en) * 2011-09-21 2013-03-21 Bristol-Myers Squibb Company Novel betulinic acid derivatives with antiviral activity
WO2017149518A1 (en) * 2016-03-04 2017-09-08 Hetero Labs Limited C-3 novel triterpene with c-17 amine derivatives as hiv inhibitors
WO2020165741A1 (en) * 2019-02-11 2020-08-20 Hetero Labs Limited Novel triterpene derivatives as hiv inhibitors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2021161206A1 *

Also Published As

Publication number Publication date
EP4103579A1 (en) 2022-12-21
WO2021161206A1 (en) 2021-08-19
ZA202209130B (en) 2023-05-31
JP2023513331A (en) 2023-03-30
CN115380040A (en) 2022-11-22
US20230174570A1 (en) 2023-06-08

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A4 Supplementary search report drawn up and despatched

Effective date: 20240328

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 31/18 20060101ALI20240322BHEP

Ipc: C07J 63/00 20060101AFI20240322BHEP