EP4084948A1 - Peel seal tube closure - Google Patents

Peel seal tube closure

Info

Publication number
EP4084948A1
EP4084948A1 EP19958639.7A EP19958639A EP4084948A1 EP 4084948 A1 EP4084948 A1 EP 4084948A1 EP 19958639 A EP19958639 A EP 19958639A EP 4084948 A1 EP4084948 A1 EP 4084948A1
Authority
EP
European Patent Office
Prior art keywords
tube
seal
medical
opposing sides
opening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19958639.7A
Other languages
German (de)
French (fr)
Other versions
EP4084948A4 (en
Inventor
Peng Yuan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Medical Care Deutschland GmbH
Original Assignee
Fresenius Medical Care Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Medical Care Deutschland GmbH filed Critical Fresenius Medical Care Deutschland GmbH
Publication of EP4084948A1 publication Critical patent/EP4084948A1/en
Publication of EP4084948A4 publication Critical patent/EP4084948A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2024—Separating means having peelable seals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/221—Frangible or pierceable closures within tubing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/76—Making non-permanent or releasable joints
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/01—General aspects dealing with the joint area or with the area to be joined
    • B29C66/05—Particular design of joint configurations
    • B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/11—Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
    • B29C66/112—Single lapped joints
    • B29C66/1122—Single lap to lap joints, i.e. overlap joints
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/40—General aspects of joining substantially flat articles, e.g. plates, sheets or web-like materials; Making flat seams in tubular or hollow articles; Joining single elements to substantially flat surfaces
    • B29C66/41—Joining substantially flat articles ; Making flat seams in tubular or hollow articles
    • B29C66/43—Joining a relatively small portion of the surface of said articles
    • B29C66/431—Joining the articles to themselves
    • B29C66/4312—Joining the articles to themselves for making flat seams in tubular or hollow articles, e.g. transversal seams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/04—Dielectric heating, e.g. high-frequency welding, i.e. radio frequency welding of plastic materials having dielectric properties, e.g. PVC
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/08—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using ultrasonic vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/80—General aspects of machine operations or constructions and parts thereof
    • B29C66/84—Specific machine types or machines suitable for specific applications
    • B29C66/857—Medical tube welding machines
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2023/00—Tubular articles
    • B29L2023/005—Hoses, i.e. flexible
    • B29L2023/007—Medical tubes other than catheters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7148—Blood bags, medical bags

Definitions

  • the present invention relates to a peel seal tube closure for a medical container, a medical container comprising a tube with a peel seal tube closure and a hand tool to open said peel seal.
  • Plastic film containers such as bags for the administration of medical fluids are known. These containers are made from flexible film which is folded and sealed together along peripheral side edges. Further, the containers typically have an inlet and an outlet. The containers further typically have a device for piercing the outlet and establishing a fluid communication between the patient and the solution inside the container.
  • the solution may then be exhausted from the device to an administration set and/or patient.
  • medical fluids are liquid medicaments, substitution fluids, blood, or solutions for peritoneal dialysis or hemofiltration treatment.
  • the medical fluid bags comprise a short tubing, which is attached to the fluid bag by gluing or welding.
  • the tubing also comprises one or more means to close the container. Said means known in the art include caps, rods or frangible pins. The latter are opened by kinking the tube and at the same time breaking the pin inside the tube. Examples of frangible pins are depicted in figure 1 (top and middle figure) .
  • Peritoneal dialysis (PD) solutions are one type of dialysis solutions which are typically supplied in film containers.
  • frangible pins are used to control fluid pass in PD bag systems.
  • Frangible pins in their closed state isolate the PD solution from outer environment.
  • the frangible pin is broken and PD solution flows into patient or into an APD machine.
  • the present invention relates to a peel seal tube to releasably close a medical fluid container.
  • Peel seams are known in multi-chambered plastic film containers. These seams releasably separate the individual chambers of such multi-chamber containers. Prior to use, the seam is opened by exerting pressure on at least one of the liquid-filled chambers and the content of the two or more chambers is thoroughly mixed.
  • the present invention relates to a peelable tube seal which is designed to control fluid pass and has the same function as a frangible pin.
  • the peelable tube seal of the present invention has several advantages over conventional closing means. It does not require any manual assembly of a frangible pin and a tube. It can be adapted to an automated process and thereby increasing production output. Furthermore, it is cost-efficient because it does not require the plastic frangible.
  • the tube seal of the present invention is made by a process comprising the following steps:
  • the melting of the tube material in the compressed zone in step (II) can be achieved by thermal heat, radio frequency energy or ultrasonic energy.
  • the shape of the tube can be circular, angular, oval, hexagonal or octagonal. In a preferred embodiment of the present invention the tube has a circular shape.
  • FIG. 2 shows a medical container with a peelable tube seal according to the present invention the present.
  • a solution bag (1) is equipped with at least one tube (2) , which acts as a fluid outlet.
  • the tube (2) is closed by a welding portion (3) in tube (2) , which releasably closes the bag (1) and tube (2) assembly and prevents the medical fluid inside the bag (1) from flowing out.
  • the releasable welding portion (3) is as shown in Figure 3.
  • To open the peelable seal pressure is exerted perpendicular to the longitudinal axis of the tube (2) and at the same time parallel with or along the welded portion (3) .
  • the opening of tube seal is typically done by a pinch grip of the thumb and an opposing finger of the same hand, e.g., the index finger or the middle finger.
  • FIG. 4 The process of opening the container and releasing the medical fluid is shown in Figure 4.
  • the solution bag (1) is closed by the releasable tube seal or welding portion (3) .
  • Fig. 4 left When, e.g., a PD treatment cycle begins, the patient or a nurse squeezes the releasable welding (3) to open the container and PD solution can flow out of solution bag (1) through tube (2) into the patient or a PD cycler.
  • the tube seal has a predominantly linear shape. In further embodiments of the present invention the seal may have a non-linear shape.
  • Figure 5 shows alternative embodiments of the peelable tube seal of the present invention with different welding line shapes. By using different welding line shapes and dimensions, the tube can be reopened fully or partially with different reopening force. In yet another embodiment of the present invention more than one peelable welding can be combined for use in the tube.
  • the peelable tube of the present invention is preferably opened manually by exerting pressure along the seal on opposing sides of the tube. This can be done by a pinch grip of thumb and the index finger of the same hand.
  • the force a subject can exert in a pinch grip depends on sex, age and overall physical condition of the subject. Typically, younger, fitter persons can produce higher pinch forces than elderly persons. Higher pinch forces can be found with men compared to female test persons.
  • the required pinch force must not exceed a maximum value. In a preferred embodiment of the present invention the maximum pinch force required to open the seal is below 100 N, preferably below 90 N.
  • the maximum pinch force required to open the seal is below 60 N, preferably below 50 N.
  • a minimum opening pinch force is necessary to avoid premature opening of the seal and a leakage during handling and transport.
  • the minimum opening pinch force can be adjusted to the bag volume, the tube diameter, the tube material and the expected transport conditions.
  • the seal can be opened by a hand tool, which leverages the force of the fingers and thereby reduces the effort.
  • a hand tool is particularly useful to help elderly patients to open the peel seal of the present invention without the help of others.
  • Yet another application of said hand tool is to further increase the required pinch force necessary to open the peel seal of the present invention as mentioned above to values higher than 100 N and still enabling a great variety of persons to open the peel seal.
  • FIG. 6 shows an embodiment of tool. It comprises the following parts: top handle (4) , rotating shaft (5) , bottom handle (6) .
  • the top handle (4) can rotate around shaft (5) .
  • the means to hold the tube in place for opening comprises at least one latch.
  • Figure 7 shows the process to open a tube seal with a hand tool as described above.
  • a first step the tube with the peelable tube seal onto the slots of bottom handle 6.
  • the top handle 4 is rotated and pressed onto the bottom handle 6 to squeeze the tube until the seal is opened.

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Fluid Mechanics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

A tube (2) for a medical fluid container comprising a tube seal whereby the tube (2) is releasably closed in at least one section, wherein the closed section is obtained by pressing opposing sides of the tube (2) together so that the inner walls of the lumen are in direct contact with each other and the walls are welded together, characterized in that the pinch force to open the seal is below 100 N. Also disclosed are a method of manufacturing a tube seal, a medical fluid container and a hand tool for opening a tube seal.

Description

    Peel seal tube closure Technical field
  • The present invention relates to a peel seal tube closure for a medical container, a medical container comprising a tube with a peel seal tube closure and a hand tool to open said peel seal.
  • Background art
  • Plastic film containers such as bags for the administration of medical fluids are known. These containers are made from flexible film which is folded and sealed together along peripheral side edges. Further, the containers typically have an inlet and an outlet. The containers further typically have a device for piercing the outlet and establishing a fluid communication between the patient and the solution inside the container.
  • The solution may then be exhausted from the device to an administration set and/or patient. Examples for medical fluids are liquid medicaments, substitution fluids, blood, or solutions for peritoneal dialysis or hemofiltration treatment. To facilitate a fluid connection with the patient the medical fluid bags comprise a short tubing, which is attached to the fluid bag by gluing or welding. To releasably seal the medical fluid container the tubing also comprises one or more means to close the container. Said means known in the art include caps, rods or frangible pins. The latter are opened by kinking the tube and at the same time breaking the pin inside the tube. Examples of frangible pins are depicted in figure 1 (top and middle figure) .
  • Peritoneal dialysis (PD) solutions are one type of dialysis solutions which are typically supplied in film containers. Usually, frangible pins are used to control fluid pass in PD bag systems. Frangible pins in their closed state isolate the PD solution from outer environment. When the patient starts the PD treatment procedure, the frangible pin is broken and PD solution flows into patient or into an APD machine.
  • The three closing devices of the prior art (caps, rods or frangible pins) , have the disadvantage in common that a separate component must be inserted into the outlet tube of medical container. This requires an extra production step, which is often performed manually. There is a need to provide a cost-efficient alternative to conventional closing means for medical fluid containers.
  • The present invention relates to a peel seal tube to releasably close a medical fluid container. Peel seams are known in multi-chambered plastic film containers. These seams releasably separate the individual chambers of such multi-chamber containers. Prior to use, the seam is opened by exerting pressure on at least one of the liquid-filled chambers and the content of the two or more chambers is thoroughly mixed.
  • Description of the invention
  • The present invention relates to a peelable tube seal which is designed to control fluid pass and has the same function as a frangible pin.
  • The peelable tube seal of the present invention has several advantages over conventional closing means. It does not require any manual assembly of a frangible pin and a tube. It can be adapted to an automated process and thereby increasing production output. Furthermore, it is cost-efficient because it does not require the plastic frangible.
  • The tube seal of the present invention is made by a process comprising the following steps:
  • (I) squeezing a tube perpendicular to the longitudinal axis so that the opposing sides of the inner lumen of the tube are in direct contact and
  • (II) heating the compressed zone so that the tube material melts and the opposing sides stick together.
  • The melting of the tube material in the compressed zone in step (II) can be achieved by thermal heat, radio frequency energy or ultrasonic energy.
  • The shape of the tube can be circular, angular, oval, hexagonal or octagonal. In a preferred embodiment of the present invention the tube has a circular shape.
  • Figure 2 shows a medical container with a peelable tube seal according to the present invention the present. A solution bag (1) is equipped with at least one tube (2) , which acts as a fluid outlet. The tube (2) is closed by a welding portion (3) in tube (2) , which releasably closes the bag (1) and tube (2) assembly and prevents the medical fluid inside the bag (1) from flowing out.
  • The releasable welding portion (3) is as shown in Figure 3. To open the peelable seal pressure is exerted perpendicular to the longitudinal axis of the tube (2) and at the same time parallel with or along the welded portion (3) . In case the opening of tube seal is performed manually, it is typically done by a pinch grip of the thumb and an opposing finger of the same hand, e.g., the index finger or the middle finger.
  • The process of opening the container and releasing the medical fluid is shown in Figure 4. Before use, the solution bag (1) is closed by the releasable tube seal or welding portion (3) . (Fig. 4 left) When, e.g., a PD treatment cycle begins, the patient or a nurse squeezes the releasable welding (3) to open the container and PD solution can flow out of solution bag (1) through tube (2) into the patient or a PD cycler.
  • In one embodiment of the present invention the tube seal has a predominantly linear shape. In further embodiments of the present invention the seal may have a non-linear shape. Figure 5 shows alternative embodiments of the peelable tube seal of the present invention with different welding line shapes. By using different welding line shapes and dimensions, the tube can be reopened fully or partially with different reopening force. In yet another embodiment of the present invention more than one peelable welding can be combined for use in the tube.
  • The peelable tube of the present invention is preferably opened manually by exerting pressure along the seal on opposing sides of the tube. This can be done by a pinch grip of thumb and the index finger of the same hand. The force a subject can exert in a pinch grip depends on sex, age and overall physical condition of the subject. Typically, younger, fitter persons can produce higher pinch forces than elderly persons. Higher pinch forces can be found with men compared to female test persons. To enable a great variety of persons to open the peelable seal, the required pinch force must not exceed a maximum value. In a preferred embodiment of the present invention the maximum pinch force required to open the seal is below 100 N, preferably below 90 N. In a most preferred embodiment of the present invention the maximum pinch force required to open the seal is below 60 N, preferably below 50 N.  On the other hand, a minimum opening pinch force is necessary to avoid premature opening of the seal and a leakage during handling and transport. The minimum opening pinch force can be adjusted to the bag volume, the tube diameter, the tube material and the expected transport conditions.
  • Alternatively, the seal can be opened by a hand tool, which leverages the force of the fingers and thereby reduces the effort. Such a hand tool is particularly useful to help elderly patients to open the peel seal of the present invention without the help of others.
  • Yet another application of said hand tool is to further increase the required pinch force necessary to open the peel seal of the present invention as mentioned above to values higher than 100 N and still enabling a great variety of persons to open the peel seal.
  • An example of such a hand tool is depicted in figure 6. Figure 6 shows an embodiment of tool. It comprises the following parts: top handle (4) , rotating shaft (5) , bottom handle (6) . The top handle (4) can rotate around shaft (5) . There are slots, grips or latches on the top handle (4) and/or the bottom handle (6) to accommodate the tube and to hold and fix the tube in the correct orientation for opening. I.e., to hold the tube in such an orientation that upon closing of the top handle (4) and the bottom handle (6) pressure is exerted on the tube in parallel to the seal and substantially on the sealed portion of the tube. In one embodiment of the present invention the means to hold the tube in place for opening comprises at least one latch.
  • Figure 7 shows the process to open a tube seal with a hand tool as described above. In a first step the tube with the peelable tube seal onto the slots of bottom handle 6. Then, the top handle 4 is rotated and pressed onto the bottom handle 6 to squeeze the tube until the seal is opened.

Claims (8)

  1. Tube for a medical fluid container comprising a tube seal whereby the tube is releasably closed in at least one section, wherein the closed section is obtained by pressing opposing sides of the tube together so that the inner walls of the lumen are in direct contact with each other and the walls are welded together, characterized in that the pinch force to open the seal is below 100 N.
  2. Tube for a medical container according to claim 1 wherein the pinch force to open the seal is below 60 N.
  3. Tube for a medical container according to claim 1 or 2 wherein the welding of the seal has a linear shape.
  4. Tube for a medical container according to claim 1 -3 wherein the tube has a circular shape.
  5. Method of manufacturing a tube seal according to any of claim1 -4 comprising the steps of:
    a. Squeezing the tube by exerting pressure on opposing sides perpendicular to the longitudinal axis of the tube insofar that the opposing sides of the tube are in contact with each other,
    b. Welding the compressed zone by heat energy, radio frequency energy or ultrasonic energy.
  6. Medical fluid container comprising at least one tube wherein the tube is releasably closed with a seal according to claims 1 to 4.
  7. Hand tool for opening a tube seal according to claim 1 to 4 comprising a top handle (4) , a bottom handle (6) and an axis (5) wherein the top handle (4) can rotate around axis (5) and wherein either the top handle or the bottom handle includes a means to accommodate and hold the tube in place for opening.
  8. Hand tool according to claim 7 wherein the means to accommodate and hold the tube in place for opening comprises at least one latch.
EP19958639.7A 2019-12-31 2019-12-31 TUBE CLOSURE WITH PEEL LID Pending EP4084948A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2019/130522 WO2021134486A1 (en) 2019-12-31 2019-12-31 Peel seal tube closure

Publications (2)

Publication Number Publication Date
EP4084948A1 true EP4084948A1 (en) 2022-11-09
EP4084948A4 EP4084948A4 (en) 2024-01-03

Family

ID=76687518

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19958639.7A Pending EP4084948A4 (en) 2019-12-31 2019-12-31 TUBE CLOSURE WITH PEEL LID

Country Status (3)

Country Link
EP (1) EP4084948A4 (en)
CN (1) CN114929460A (en)
WO (1) WO2021134486A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250249158A1 (en) * 2024-02-06 2025-08-07 Baxter International Inc. Injection stretch blow molded peritoneal dialysis solution container system
WO2025170882A1 (en) * 2024-02-06 2025-08-14 Baxter International Inc. Peelable tube

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2619935C3 (en) * 1976-05-06 1978-11-16 Daimler-Benz Ag, 7000 Stuttgart Device for transverse welding of hose pieces made of thermoplastic material, in particular vacuum-tight hoses
DE102005019855A1 (en) * 2005-04-28 2006-11-09 Fresenius Hemocare Gmbh Lead, in particular lead of a blood tubing or blood bag system
CH698008B1 (en) * 2005-11-25 2009-04-30 Belcap Switzerland Ag A sealed fluid bag with welded drinking or dispensing nozzle.
FR2912727B1 (en) * 2007-02-19 2013-07-19 Cryo Bio System PACKAGING TUBE OF A PREDETERMINED VOLUME OF BIOLOGICAL SUBSTANCE TO BE PRESERVED AT LOW TEMPERATURE AND SYSTEM COMPRISING SAME
CN202295651U (en) * 2011-11-02 2012-07-04 深圳市通产丽星股份有限公司 Squeeze-opened packing container
CN207594345U (en) * 2017-10-18 2018-07-10 深圳市爱康生物科技有限公司 A kind of hose limiting device suitable for automatic blood component separator

Also Published As

Publication number Publication date
CN114929460A (en) 2022-08-19
WO2021134486A1 (en) 2021-07-08
EP4084948A4 (en) 2024-01-03

Similar Documents

Publication Publication Date Title
EP0079326B1 (en) Fluid transfer assembly
US3648704A (en) Disposable catheter apparatus
US4381776A (en) Anticoagulant dispensing apparatus and method of use
US3945380A (en) Plasmapheresis assembly
TW534825B (en) Clamp device, method and system for exchanging a solution
EP0596497B1 (en) Bag for containing at least two separate substances that are to be mixed
EP1883386B1 (en) Access port with safety tab and fluid container employing same
US3276447A (en) Flexible tubing clamp
US2847007A (en) Fluid handling unit and apparatus
KR101510084B1 (en) Compartment container
US4717388A (en) Bag and valve assembly for medical use
BR122020014232B1 (en) COMBINATION DEVICE TO COMBINE A FLUID FROM A CONTAINER UNIT
EP0605889B1 (en) Solution bag with plastic connecting tube
US4368729A (en) Aseptic system for total parenteral nutrition and the like
US20110238022A1 (en) Corporeal drainage system
JPH0311234B2 (en)
JP2009543008A (en) Heat welded tube connector
WO2021134486A1 (en) Peel seal tube closure
US4722727A (en) Flexible container
KR102736491B1 (en) Sterile flexible package with pressure compensator for the dosed reconstitution of fluid medicinal or nutritional substances to be administered to patients by infusion or injection
CN106860003A (en) A kind of dispenser
US3368560A (en) Outlet fitting for plastic parenteral solution container
JP2002518098A (en) Membrane port for container
JPS6320550B2 (en)
JP7367179B2 (en) Bag-shaped container and its manufacturing method

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20220801

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A61J 1/20 20060101ALI20230817BHEP

Ipc: A61J 1/00 20060101ALI20230817BHEP

Ipc: B65D 33/16 20060101ALI20230817BHEP

Ipc: B29C 65/02 20060101ALI20230817BHEP

Ipc: B29C 65/76 20060101AFI20230817BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20231124

RIC1 Information provided on ipc code assigned before grant

Ipc: A61J 1/20 20060101ALI20231123BHEP

Ipc: A61J 1/00 20060101ALI20231123BHEP

Ipc: B65D 33/16 20060101ALI20231123BHEP

Ipc: B29C 65/02 20060101ALI20231123BHEP

Ipc: B29C 65/76 20060101AFI20231123BHEP

RA4 Supplementary search report drawn up and despatched (corrected)

Effective date: 20231205

RIC1 Information provided on ipc code assigned before grant

Ipc: A61J 1/20 20060101ALI20231128BHEP

Ipc: A61J 1/00 20060101ALI20231128BHEP

Ipc: B65D 33/16 20060101ALI20231128BHEP

Ipc: B29C 65/02 20060101ALI20231128BHEP

Ipc: B29C 65/76 20060101AFI20231128BHEP

RAP3 Party data changed (applicant data changed or rights of an application transferred)

Owner name: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH