EP4031922A4 - Virtual fiducials - Google Patents

Virtual fiducials Download PDF

Info

Publication number
EP4031922A4
EP4031922A4 EP20876361.5A EP20876361A EP4031922A4 EP 4031922 A4 EP4031922 A4 EP 4031922A4 EP 20876361 A EP20876361 A EP 20876361A EP 4031922 A4 EP4031922 A4 EP 4031922A4
Authority
EP
European Patent Office
Prior art keywords
virtual fiducials
fiducials
virtual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20876361.5A
Other languages
German (de)
French (fr)
Other versions
EP4031922A1 (en
Inventor
Diping Che
James CHE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sequlite Genomics Us Inc
Original Assignee
Sequlite Genomics Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/658,052 external-priority patent/US10895727B1/en
Application filed by Sequlite Genomics Us Inc filed Critical Sequlite Genomics Us Inc
Publication of EP4031922A1 publication Critical patent/EP4031922A1/en
Publication of EP4031922A4 publication Critical patent/EP4031922A4/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/245—Devices for focusing using auxiliary sources, detectors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/006—Optical details of the image generation focusing arrangements; selection of the plane to be imaged
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/32—Fiducial marks and measuring scales within the optical system
    • G02B27/34—Fiducial marks and measuring scales within the optical system illuminated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
EP20876361.5A 2019-10-19 2020-10-19 Virtual fiducials Pending EP4031922A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/658,052 US10895727B1 (en) 2019-10-19 2019-10-19 Microscope for locating structures on the inner surface of a fluidic channel
US202016824632A 2020-03-19 2020-03-19
PCT/US2020/056302 WO2021077075A1 (en) 2019-10-19 2020-10-19 Virtual fiducials

Publications (2)

Publication Number Publication Date
EP4031922A1 EP4031922A1 (en) 2022-07-27
EP4031922A4 true EP4031922A4 (en) 2022-12-07

Family

ID=75538690

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20876361.5A Pending EP4031922A4 (en) 2019-10-19 2020-10-19 Virtual fiducials

Country Status (7)

Country Link
EP (1) EP4031922A4 (en)
JP (1) JP2022552743A (en)
KR (1) KR20220084147A (en)
CN (1) CN114585958B (en)
AU (1) AU2020366521B2 (en)
CA (1) CA3158318A1 (en)
WO (1) WO2021077075A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114280806B (en) * 2022-02-10 2024-08-13 中国人民解放军陆军装甲兵学院 Light collimation method based on kinoform

Citations (3)

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JPH09133856A (en) * 1995-11-07 1997-05-20 Nikon Corp Automatic focus detecting device for microscope
WO2010103389A1 (en) * 2009-03-11 2010-09-16 Sensovation Ag Autofocus method and autofocus device
WO2016061484A2 (en) * 2014-10-16 2016-04-21 Illumina, Inc. Optical scanning systems for in situ genetic analysis

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JP3265668B2 (en) * 1993-01-13 2002-03-11 株式会社ニコン How to calculate the best focus position
JP3619571B2 (en) * 1995-06-06 2005-02-09 オリンパス株式会社 Focus detection apparatus and design method for optical microscope
US6025905A (en) * 1996-12-31 2000-02-15 Cognex Corporation System for obtaining a uniform illumination reflectance image during periodic structured illumination
US6181474B1 (en) * 1999-03-22 2001-01-30 Kovex Corporation Scanning confocal microscope with objective lens position tracking
US6974938B1 (en) * 2000-03-08 2005-12-13 Tibotec Bvba Microscope having a stable autofocusing apparatus
JP2002277736A (en) * 2001-03-21 2002-09-25 Olympus Optical Co Ltd Image pickup device
JP3867143B2 (en) * 2003-06-25 2007-01-10 独立行政法人産業技術総合研究所 Three-dimensional microscope system and image display method
JP2005134834A (en) * 2003-10-31 2005-05-26 Olympus Corp Imaging unit and electronic imaging equipment
US7057826B2 (en) * 2004-03-22 2006-06-06 Angstrom Inc. Small and fast zoom system
US7295303B1 (en) * 2004-03-25 2007-11-13 Kla-Tencor Technologies Corporation Methods and apparatus for inspecting a sample
JP2006047922A (en) * 2004-08-09 2006-02-16 Nikon Corp Image forming apparatus
JP2006084794A (en) * 2004-09-16 2006-03-30 Olympus Corp Observation device with focal position control mechanism
EP2453223B1 (en) * 2005-04-12 2019-07-03 Caliper Life Sciences Inc. Optical detection system for a microfluidic device and method for aligning and focusing an optical detection system
JP5058483B2 (en) * 2005-09-14 2012-10-24 オリンパス株式会社 Long-term or continuous detection method for biological samples
JP2009116271A (en) * 2007-11-09 2009-05-28 Nikon Corp Focusing arrangement and microscope apparatus
US7723657B2 (en) * 2007-11-16 2010-05-25 Mitutoyo Corporation Focus detection apparatus having extended detection range
US9213176B2 (en) * 2008-12-02 2015-12-15 The Regents Of The University Of California Imaging arrangement and microscope
TWI456254B (en) * 2010-05-19 2014-10-11 Ind Tech Res Inst Fluorescence micro imaging system
WO2013027459A1 (en) * 2011-08-24 2013-02-28 オリンパスメディカルシステムズ株式会社 Image capture device and iamge capture device system
DE102011082756A1 (en) * 2011-09-15 2013-03-21 Leica Microsystems (Schweiz) Ag Autofocusing method and device for a microscope
DE102012009836A1 (en) * 2012-05-16 2013-11-21 Carl Zeiss Microscopy Gmbh Light microscope and method for image acquisition with a light microscope
AU2013295679A1 (en) * 2012-07-25 2015-01-29 Theranos, Inc. Image analysis and measurement of biological samples
EP2971011B1 (en) * 2013-03-15 2021-11-10 The Regents of the University of California High-throughput cargo delivery into live cells using photothermal platforms
JP6286183B2 (en) * 2013-11-07 2018-02-28 株式会社日立ハイテクノロジーズ Analysis equipment
JP6197880B2 (en) * 2013-12-12 2017-09-20 株式会社ニコン Structured illumination microscope, structured illumination method, and program
CA2991920C (en) * 2015-04-23 2024-05-14 The University Of British Columbia Multifocal method and apparatus for stabilization of optical systems
DE102015209402A1 (en) * 2015-05-22 2016-11-24 Sirona Dental Systems Gmbh Device for optical 3D measurement of an object
US10558029B2 (en) * 2016-10-27 2020-02-11 Scopio Labs Ltd. System for image reconstruction using a known pattern
EP3574307A4 (en) * 2017-01-26 2020-10-21 Azure Biosystems, Inc. Devices and methods for imaging biomolecules
JP2019078866A (en) * 2017-10-24 2019-05-23 オリンパス株式会社 Microscope system, observation method, and observation program
US10895727B1 (en) * 2019-10-19 2021-01-19 SequLITE Genomics US, Inc. Microscope for locating structures on the inner surface of a fluidic channel

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09133856A (en) * 1995-11-07 1997-05-20 Nikon Corp Automatic focus detecting device for microscope
WO2010103389A1 (en) * 2009-03-11 2010-09-16 Sensovation Ag Autofocus method and autofocus device
WO2016061484A2 (en) * 2014-10-16 2016-04-21 Illumina, Inc. Optical scanning systems for in situ genetic analysis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2021077075A1 *

Also Published As

Publication number Publication date
JP2022552743A (en) 2022-12-19
CA3158318A1 (en) 2021-04-20
AU2020366521B2 (en) 2024-03-07
KR20220084147A (en) 2022-06-21
AU2020366521A1 (en) 2022-05-19
EP4031922A1 (en) 2022-07-27
CN114585958B (en) 2024-05-28
CN114585958A (en) 2022-06-03
WO2021077075A1 (en) 2021-04-22

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