EP4028075A1

EP4028075A1 - System and method for connecting a concentrate container with a blood treatment device

Info

Publication number: EP4028075A1
Application number: EP20768048.9A
Authority: EP
Inventors: Winfried Brehm; Philippe Laffay; Gerhard Wiesen
Original assignee: Fresenius Medical Care Deutschland GmbH
Current assignee: Fresenius Medical Care Deutschland GmbH
Priority date: 2019-09-12
Filing date: 2020-09-10
Publication date: 2022-07-20
Also published as: WO2021048301A1; CN114364413A; TW202116287A; TWI858127B

Abstract

The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.

Description

System and method for connecting a concentrate container with a blood treatment device

Description

The present invention refers to a system and a method for connecting a concentrate container with a blood treatment device, preferably a dialysis machine for renal re placement therapy. Further aspects of the present invention refer to a container and a blood treatment device configured to be used in a method according to the present invention.

For chronic blood treatment, especially for chronic dialysis, nowadays almost exclu sively bicarbonate-based dialysis solutions are used, that are generated by the blood treatment device itself / online during treatment by diluting an acidic and a basic con centrate, preferably a powder concentrate, with water. Thus, it is established practice that the basic concentrate is generated online during the treatment, i.e. that liquid basic concentrate is continuously generated during the treatment by diluting a dry concentrate/powder concentrate with water.

For this purpose, dry powder concentrate is generally provided in a container that is fluidically coupled to the blood treatment device so that water can be dispensed into the container by the blood treatment device for dissolving the dry concentrate. Simul taneously the basic liquid concentrate / the bicarbonate solution generated in this way is withdrawn by the blood treatment device from the concentrate container. Such a conventional concentrate container is known from e.g. EP1344550.

In conventional blood treatment devices known from the prior art, the concentrate container cannot be connected to the hydraulic system/fluidics system of the blood treatment device during disinfection/rinsing of the blood treatment device.

For this reason medical personnel has to connect the concentrate container to the blood treatment device after disinfection/rinsing of the blood treatment device and prior to preparing/priming the extracorporeal circuit of the blood treatment device for treatment. This necessitates medical personnel being present at the blood treatment device at exactly this point in time.

It is thus an object of the present invention to provide a container for concentrate that can be mounted to the blood treatment machine at an arbitrary and convenient point in time and also makes the process of fluidically coupling the container to the blood treatment device more hygienic. The present invention achieves this object, because according to the present invention the container can be attached to the blood treat ment machine prior to the point in time a fluid connection between the machine and the container is established, so that after disinfection or cleaning of the blood treat ment machine is finished, the container can easily be connected to the blood treat ment machine with a minimum of handling steps by medical personnel.

In other words, according to the present invention by the attachment of the container to the blood treatment device, everything is pre set-up / arranged for actually fluidical ly connecting the container to the blood treatment device, so that the number of han dling steps by medical personnel and thus the risk of contaminations can be reduced.

Furthermore, according to the prior art, a certain amount of force is necessary to connect the container to the blood treatment device. In order to make the blood treatment device and the concentrate container as user-friendly as possible, conven- tionally the blood treatment machine and the corresponding concentrate container are configured in such a way that a connection element of the container is inserted into a connection element of the machine in a downward movement, so that gravity assists the movement of the connection element of the container into / over the con nection element of the machine.

However, this configuration has the disadvantage that because of the opening of the connection element of the container being opened in a downward direction (so that it can be coupled with a corresponding connection element of the blood treatment de vice by moving the connection element of the container from above in a downwards movement of the connection element of the blood treatment device) after a treatment has ended and the concentrate container is removed from the blood treatment de vice, liquid concentrate can drip from the connection element of the container. This liquid concentrate can then collect in the connection element of the blood treatment device causing undesired crystallization and thus potential clogging of the connection element of the blood treatment device.

In addition to that, in blood treatment devices according to the prior art, liquid concen trate can spill, leak or drop from a withdrawal line of the blood treatment device con figured to withdraw concentrate from the container upon disconnection of the con tainer from the blood treatment device. Since the liquid concentrate contains solutes, crystallization may occur as an additional disadvantage to these spillages generally not being hygienic.

This liquid concentrate can then collect in the connection element of the blood treat ment device causing undesired crystallization and thus potential clogging of the con nection element of the blood treatment device.

Thus, it is a further object of the present invention to provide a container and/or a system comprising a container and a blood treatment device, which avoids such un desired dripping of liquid concentrate during the removal of the container from the blood treatment device and thus improves hygiene. This object is solved by the present invention. The present invention uses the con tainer to collect any drops dripping from the connection elements of the blood treat ment device. For this purpose, the opening element(s) of a container according to the present invention are preferably opened in an upward direction so that the connec tion element(s) of the blood treatment device can be inserted into the openings / connection element(s) of the container from above in a downward motion or the con nection elements of the container can be moved in an upward motion so that the connection element(s) of the blood treatment device can be inserted into the open ings / connection element(s) of the container.

Furthermore, the present invention provides a container that is easier and cheaper to manufacture as fluid flows along connection elements in the form of linear channels through a connection portion of the container from the blood treatment device into the container and vice versa. In other words, the structure of the connection portion of the container can be simplified in comparison to the prior art in which the fact that the connection portion generally is connected to the blood treatment device via a down ward movement dictates a design in which the openings of the container are opened at a lower surface of the connection portion. Thus, according to the prior art fluid flow through the connection portion of the container is not strictly linear / unidirectional but the fluid is diverted in multiple directions which requires a more complex design and more material.

In addition to that, the structure of a container according to the present invention and especially the structure of the connection portion thereof allows filters to be mounted more easily into the openings of a fluid inlet and / or outlet of the container.

A container for concentrate according to an aspect of the invention comprises a main body for containing concentrate, at least one attachment element configured to re versibly attach the container to at least one corresponding attachment element pre sent on a blood treatment device, and at least one connection element, configured to interact with at least one corresponding connection element present on a blood treatment device to fluidically couple the container with the blood treatment device, wherein the at least one attachment element projects in a first direction and the at least one connection element projects in a second direction that is oriented essential ly at right angles to the first direction.

Alternatively or additionally, the at least one attachment element and the at least one connection element can project in parallel directions. For example, the parallel direc tions can project essentially at right angles to a longitudinal axis of a main body of the container holding the concentrate. The parallel directions can also project essentially at right angles to a side surface axis of a main body of the blood treatment device if the container is attached at and / or connected to the blood treatment device. In other words, according to this embodiment, the container is configured to be attached at / connected to a blood treatment device in the fashion of a plug and socket. Such an arrangement can be particularly stable and easy to use.

According to a preferred embodiment, the first direction in that the at least one at tachment element projects is oriented essentially at right angles to the longitudinal axis of the main body of the container. The attachment element of the blood device is inserted into the attachment element of the container preferably along the first direc tion. If the attachment element of the container is hook-shaped, an attachment ele ment of the blood treatment device that is inserted into the hook-shaped attachment element of the container preferably projects along the first direction.

Furthermore, it has proved advantageous if the second direction in that the at least one connection element projects is oriented essentially in parallel to the longitudinal axis of the main body of the container and the at least one connection element has the form of a hollow cylinder opened at an end surface of the container opposite to the main body of the container and configured to receive a corresponding connection element, e.g. a spout, of the blood treatment device. The at least one connection element of the container preferably has an opening at the (top) end surface of the container facing away from the main body of the container.

According to one preferred embodiment of the invention, the container comprises two attachment elements each formed as a hook configured to be hooked over a corre sponding attachment element present on a blood treatment device that is preferably formed as stud, preferably comprising a circumferential groove, for receiving the hook of the container, thereby to reversibly attach the container to the blood treat ment device.

According to an alternative embodiment of the invention the container comprises two attachment elements each formed as a hollow cylinder configured to receive a corre sponding attachment element present on a blood treatment device formed as a stud to be inserted into the hollow cylinder of the container, thereby to reversibly attach the container to the blood treatment device.

According to another aspect of the invention the container comprises two connection elements in the form of hollow cylinders opened at an end surface of the container opposite to / facing away from the main body of the container and configured to re ceive a corresponding connection element, e.g. spout, of the blood treatment device, wherein the spout of the blood treatment device is inserted into each hollow cylinder in a direction projecting from the end surface of the container opposite to the main body of the container towards the main body of the container.

In order to ensure storage stability of concentrate contained within the container, the at least connection element is advantageously sealed by a lid, preferably in the form of a flexible film, that is removably attached to an end surface of the container oppo site to / facing away from the main body of the container.

For example, the lid can be glued or welded to the end surface of the container op posite to the main body of the container. When the container is attached and con nected to a blood treatment device, the end surface comprising the opening of the at least one connection element of the container preferably is facing the at least one connection element of the blood treatment device and forms a top end surface of the container.

To make the container more user friendly, the flexible film forming the lid preferably comprises a surface configured to be easily peeled from the end surface of the con tainer. In other words, the surface of the flexible film is surface-treated to allow a user to easily peel the flexible film from the end surface of the container thereby to expose the at least one connection element of the container and for example a central open ing of the container through that the container can be filled with dry concentrate.

In order to ensure correct mounting of the container to a blood treatment device, the container can be configured to attach to the blood treatment device according to a lock-and-key-configuration. For this purpose, the container can comprise two attach ment elements that are formed in different sizes and / or geometrical configurations to allow attachment of the container to a blood treatment device in only one defined mounting position. The blood treatment device in this embodiment preferably com prises two corresponding attachment elements in different sizes and / or geometrical configurations.

Alternatively or additionally, the container or the blood treatment device can comprise two connection elements that are formed in different sizes and / or geometrical con figurations to allow fluidic coupling of the container to a blood treatment device in on ly one defined mounting position. The blood treatment device or the container in this embodiment preferably comprises two corresponding connection elements.

The number of attachment elements and / or connection elements present on the container and / or the blood treatment device is arbitrary and can be varied according to specific applications.

Another aspect of the invention refers to a blood treatment device configured to be used with a container according to the present invention.

Such a blood treatment device comprises a main body, at least one attachment ele ment to that a corresponding attachment element of a container for concentrate can be attached, wherein the at least one attachment element is movable relative to the main body in a direction projecting essentially at right angles from a side surface of the main body, and at least one connection element configured to fluidically couple the blood treatment device to a container for concentrate. The main body of the blood treatment device comprises a top surface, a bottom surface and four side surfaces. Depending on the direction of view from a user, a side surface of the blood treatment device can also be referred to as a front surface.

In a preferred embodiment of the invention, the at least one attachment element of the blood treatment device has the form of a pin or stud projecting outward from a side surface of the main body and the at least one connection element has the form of a spout projecting in a direction essentially parallel to the side surface of the main body.

It has proved advantageous if the blood treatment device further comprises a mova ble and / or motorized guiding element in that preferably a cavity is formed and the at least one attachment element is mounted onto the movable and preferably motorized guiding element. The guiding element can be moved / is movable into a first position, in that the at least one connection element of the blood treatment device, preferably a spout for fluidically connecting the blood treatment device to a container, is re ceived in the cavity present on the guiding element thereby allowing the blood treat ment device to be rinsed.

In the first position, the cavity in the guiding element short-circuits and / or closes the internal fluidic circuits of the blood treatment device to form a closed circuit so that rinsing liquid can be circulated in the blood treatment device.

The guiding element can also be moved / is movable into a second position in that the spout is fluidically connected to a container attached to the at least one attach ment element of the blood treatment device. The guiding element is preferably mov able in the horizontal and / or vertical direction.

In the second position, the guiding element preferably positions the container at tached to the at least one attachment element mounted on the guiding element, es pecially the at least one connection element of the container, relative to the at least one connection element of the blood treatment device so that the container is fluidi cally coupled to the blood treatment device. The guiding element can be moved by a motor of the blood treatment device. In this case, movement of the guiding element is preferably automatic. Alternatively, the guiding element may be manually moved. In this case the blood treatment device preferably has a lever or similar structure that allows a user to manually move the guiding element. In other words, the steps of the methods disclosed herein can be performed automatically or manually.

Preferentially, the at least one connection element of the blood treatment device, for example, the spout, is movable in a vertical direction essentially parallel to a side sur face of the main body of the blood treatment device.

In a preferred embodiment, the at least one connection element of the blood treat ment device is movable in a downward direction towards a bottom surface of the main body of the blood treatment device. Additionally or alternatively, the at least one connection element of the blood treatment device is movable in an upward direction towards a top surface of the main body of the blood treatment device.

For example, the at least one connection element of the blood treatment device can be first moved upwards to allow a container attached to the attachment elements to be moved by the guiding element into a position in that the at least one connection element of the blood treatment device and the at least one connection element of the container align in a vertical direction.

Subsequently, the at least one connection element of the blood treatment device can be moved by the guiding element downwards to fluidically couple the container to the blood treatment device, for example, by inserting the at least one connection element of the blood treatment device into the at least one connection element of the contain er.

At a later stage, for example, after the concentrate contained in the container has been used up, the at least one connection element of the blood treatment device can be retracted upwards again to withdraw the at least one connection element of the blood treatment device from the at least one connection element of the container to thereby fluidically separate / decouple the container and the blood treatment device from each other.

The blood treatment device preferably further comprises a projection portion present on a side surface of the main body. The guiding element is preferably movable rela tive to the projection portion in the fashion of a drawer. In other words, the guiding element can be slidably moved relative to the projection portion in a direction essen tially at right angles to the side surface of the blood treatment device, i.e. in a hori zontal direction.

Preferably, the at least one connection element of the blood treatment device is mounted to the projection portion and can be moved in a direction essentially parallel to the side surface of the blood treatment device to project (preferably in a vertical direction downwards towards the bottom surface of the blood treatment device) out from the projection portion. Further preferably, the at least one connection element of the blood treatment device can be retracted / moved into the projection portion in a vertical direction essentially parallel to the side surface of the blood treatment device.

The movement of the guiding element and / or the at least one connection element of the blood treatment device can be performed automatically or non-automatically, mo torized and / or manually.

According to a preferred aspect of the invention, the blood treatment device compris es two attachment elements each formed as a pin / stud, preferably comprising a cir cumferential groove, for receiving a corresponding attachment element of the con tainer, preferably formed as a hook, thereby to reversibly attach the container to the blood treatment device. The hook can be inserted into the circumferential groove to prevent slipping.

To ensure correct mounting of a container to the blood treatment device in only one possible mounting position, the blood treatment device preferably comprises two at tachment elements that are formed in different sizes and / or geometrical configura- tions to allow attachment of a container to the blood treatment device in only one de fined mounting position.

Alternatively or additionally, the blood treatment device can comprise two connection elements that are formed in different sizes and / or geometrical configurations to al low fluidic coupling of a container to the blood treatment device in only one defined mounting position.

Another aspect of the present invention refers to a system comprising at least one container according to the present invention and at least one blood treatment device according to the present invention.

Preferably, the container is reversibly attached to the blood treatment device by means of the at least one attachment element present on the container interacting with the at least one attachment element present on the blood treatment device.

Additionally or alternatively, the at least one connection element of the blood treat ment device is fluidically coupled to the at least one connection element of the con tainer.

A further aspect of the present invention refers to a method for connecting a contain er for concentrate, preferably a container according to the present invention, to a blood treatment device, preferably a blood treatment device according to the present invention, comprising the steps:

- reversibly attaching the container to the blood treatment device by means of the at least one attachment element present on the container and the at least one attachment element present on the blood treatment device;

- moving the container in a horizontal direction / direction projecting essentially at right angles to a side surface of the main body of the blood treatment device towards the main body of the blood treatment device;

- moving the container and / or the at least one connection element of the blood treatment device in a vertical direction / direction projecting essentially in par allel to a side surface of the main body of the blood treatment, thereby insert- ing the at least one connection element of the blood treatment device into the at least one connection element of the container to fluidically couple the con tainer to the blood treatment device.

To prevent uncontrolled dripping of liquid from the at least one connection element of the blood treatment device that can cause contaminations and / or crystallization forming on parts of the blood treatment device, the method may comprise an addi tional step in that the container is used to capture any liquid drops or spills originating from the at least one connection element of the blood treatment device.

Such additional steps can be, for example:

- moving the container and / or the at least one connection element of the blood treatment device in a vertical direction / direction projecting essentially in par allel to a side surface of the main body of the blood treatment, thereby remov ing the at least one connection element of the blood treatment device inserted into the at least one connection element of the container from the at least one connection element of the container and thereby to fluidically decouple the container from the blood treatment device; and

- pausing the movement of the container in a position in that the at least one connection element of the container and the at least one connection element of the blood treatment device are at least partially aligned in a vertical direction / direction projecting essentially in parallel to the side surface of the main body of the blood treatment, so that any liquid dripping from the at least one con nection element of the blood treatment device is received by the at least one connection element of the container.

In other words, after disconnecting the container from the blood treatment device, the container is not immediately removed but remains for a while vertically below the connection element of the blood treatment device, e.g. a spout, to capture any drops dripping downwards from the connection element. Furthermore, the method can comprise a rinsing step in that the blood treatment de vice is rinsed prior to connecting a container to the blood treatment device or after disconnecting the container from the blood treatment device.

In this embodiment, the blood treatment device preferably comprises a movable and / or motorized guiding element comprising the at least one attachment element of the blood treatment device and further comprising a cavity configured to receive the at least one connection element of the blood treatment device. The method further comprises the step:

- moving the guiding element into a rinsing position in that the at least one con nection element of the blood treatment device is received in the cavity, thereby to fluidically seal the blood treatment device from the outside and allow rinsing of the blood treatment device.

In other words, instead of inserting the connection element of the blood treatment device into the connection element of the container to, for example, dispense water into the container to dissolve concentrate powder to form a liquid concentrate, in the rinsing position, the connection element of the blood treatment device is inserted into the cavity of the guiding element.

Thus, the internal fluidic circuit of the blood treatment device is closed and rinsing fluid can be circulated in the blood treatment device.

According to an embodiment of the invention, all method steps apart from the step of reversibly attaching the container to the blood treatment device by means of the at least one attachment element present on the container and the at least one attach ment element present on the blood treatment device are automatically performed by the blood treatment device.

This has the advantage that no personnel has to be present to manually connect the container to the blood treatment device. Instead, the container can be attached to the blood treatment device at an arbitrary and convenient time (e.g. during regular work ing hours) and the blood treatment device automatically establishes a fluid connec tion between the container and the blood treatment device as needed (on demand) at a specific time point (e.g. during night time) determined for example by a treatment regime.

According to a different embodiment of the invention, the method steps are carried out manually, e.g. medical personnel performs the movement of the container, guid ing element or other components by actuating a lever or similar structure.

In other words, the invention can be described as follows:

An aspect of the invention refers to a container for concentrate, comprising a main body for containing concentrate, a connection portion having a flat end surface and configured to connect the container to a blood treatment device, two attachment ele ments arranged at two opposing sides of the connection portion and configured to reversibly attach the container to two corresponding attachment elements present on a blood treatment device, and two connection elements each comprising an opening at the flat end surface of the connection portion and configured to interact with two corresponding connection elements present on a blood treatment device to fluidically couple the container with the blood treatment device by insertion of the connection elements present on the blood treatment device into the connection elements of the container, wherein the two attachment elements project in a first direction and the two connection elements project in a second direction that is oriented essentially at right angles to the first direction.

According to an embodiment of the invention, the second direction in that the two connection elements project is oriented essentially in parallel to the longitudinal axis of the main body of the container and the two connection elements each have the form of a hollow cylinder opened at the flat end surface of the connection portion.

Preferably, the attachment elements are each formed as a hook or as a hollow cylin der.

According to an embodiment of the invention, the two connection elements are sealed by a lid in the form of a flexible film removably attached to the flat end surface of the connection portion and wherein the flexible film can be peeled off the flat end surface of the connection portion.

According to another embodiment of the invention, the container comprises two at tachment elements that are formed in different sizes and / or geometrical configura tions to allow attachment of the container to a blood treatment device in only one defined mounting position, and / or wherein the container comprises two connection elements that are formed in different sizes and / or geometrical configurations to al low fluidical coupling of the container to a blood treatment device in only one defined mounting position.

Another aspect of the invention refers to a blood treatment device, comprising a main body, two attachment elements to that corresponding attachment elements of a con tainer for concentrate can be attached, wherein the two attachment elements are movable relative to the main body in a direction projecting essentially at right angles from a side surface of the main body, and two connection elements configured to flu- idically couple the blood treatment device to a container for concentrate.

According to an embodiment of the invention, the two attachment elements each have the form of a stud projecting out-ward from a side surface of the main body and the two connection elements each have the form of a spout projecting in a direction essentially parallel to the side sur-face of the main body.

According to another embodiment of the invention, the two attachment elements are mounted onto a movable and / or motorized guiding element, preferably movable in a vertical and a horizontal direction and comprising a cavity, that can be moved be tween a first position, in that the two connection elements for fluidically connecting the blood treatment device to a container are received in the cavity, thereby allowing the blood treatment device to be rinsed, and a second position, in that the two con nection elements are fluidically connectable or connected to a container attached to the two attachment elements of the blood treatment device. Preferably, the two connection elements are movable in a direction essentially paral lel to a side surface of the main body of the blood treatment device and are movable in a direction towards a bottom surface of the main body of the blood treatment de vice.

The two attachment elements can be formed in different sizes and / or geometrical configurations to allow attachment of a container to the blood treatment device in on ly one defined mounting position and / or the two connection elements can be formed in different sizes and / or geometrical configurations to allow fluidical coupling of a container to the blood treatment device in only one defined mounting position.

Another aspect of the invention refers to a system comprising at least one container according to the present invention and at least one blood treatment device according to the present invention, wherein preferably the container is reversibly attached to the blood treatment device by means of the two attachment elements present on the container interacting with the two attachment elements present on the blood treat ment device and / or the two connection elements of the blood treatment device are fluidically coupled to the two connection elements of the container.

Another aspect of the invention refers to a method for connecting a container for concentrate, preferably a container according to the present invention, to a blood treatment device, preferably a blood treatment device according to the present inven tion, comprising the steps:

- reversibly attaching the container to the blood treatment device by means of the two attachment elements present on the container and the two attachment elements present on the blood treatment device;

- moving the container in a direction projecting essentially at right angles to a side surface of the main body of the blood treatment device towards the main body of the blood treatment device;

- moving the container and / or the two connection elements of the blood treat ment device in a direction projecting essentially in parallel to a side surface of the main body of the blood treatment device, thereby inserting the two connec tion elements of the blood treatment device into the two connection elements of the container to fluidically couple the container to the blood treatment de vice.

According to an embodiment of the invention the method further comprises the step:

- moving the container and / or the two connection elements of the blood treat ment device in a direction projecting essentially in parallel to a side surface of the main body of the blood treatment device, thereby removing the two con nection elements of the blood treatment device inserted into the two connec tion elements of the container from the two connection elements of the con tainer; and

- pausing the movement of the container in a position in that the two connection elements of the container and the two connection elements of the blood treat ment device are at least partially aligned in a direction projecting essentially in parallel to the side surface of the main body of the blood treatment, so that any liquid dripping from the two connection elements of the blood treatment device is received by the two connection elements of the container.

Preferably, the blood treatment device comprises a movable and / or motorized guid ing element comprising the two attachment elements of the blood treatment device and further comprising a cavity configured to receive the two connection elements of the blood treatment device, further comprising the step

- moving the guiding element into a rinsing position in that the two connection elements of the blood treatment device are received in the cavity, thereby to fluidically seal the blood treatment device from the outside and allow rinsing of the blood treatment device.

According to an embodiment of the invention, all method steps apart from the step of reversibly attaching the container to the blood treatment device by means of the two attachment elements present on the container and the two attachment elements present on the blood treatment device are automatically performed by the blood treatment device. Alternatively, all method steps are carried out annually by a user operating an lever or similar structure to move the guiding element, container etc.

Further features, advantages and technical effects of the present invention become apparent from the drawings showing preferred embodiments of the invention. The drawings merely serve purposes of illustrating the invention but do not purport to limit the invention. In the drawing, same or similar components are denoted by the same reference signs.

In the drawings:

Fig. 1 shows an embodiment of a container according to the present invention;

Fig. 2 shows another embodiment of a container according to the present invention that comprises a peelable, flexible film to seal the connection elements of the con tainer;

Fig. 3 shows how a user can peel the flexible film from the end surface of the con tainer;

Fig. 4 shows a state in which the user has almost completely removed the flexible film from the top end surface of the container;

Fig. 5 shows a connection portion of a concentrate container according to the prior art;

Fig. 6 shows a connection portion of a container according to an embodiment of the present invention;

Fig. 7 shows a side view of the connection portion of figure 5;

Fig. 8 shows a side view of the connection portion of figure 6; Fig. 9 shows a sectional view of the connection portion of figure 7;

Fig. 10 shows a sectional view of the connection portion of figure 8;

Fig. 11 shows a top view of the connection portion of figure 5;

Fig. 12 shows another side view of the connection portion shown in figure 5;

Fig. 13 shows a top view of the connection portion of figure 6;

Fig. 14 shows a different side view of the connection portion of figure 6;

Fig. 15 shows a perspective top view of the connection portion of figure 6;

Fig. 16 shows a detailed view of the connection portion of figure 6 that is sealed by a flexible film;

Fig. 17 shows a blood treatment device according to the present invention compris ing two attachment elements;

Fig. 18 shows how a container is attached to the attachment elements of the blood treatment device of figure 17;

Fig. 19 shows the blood treatment device of figure 17 with a container attached thereto;

Fig. 20 shows the detailed view of the blood treatment device of figure 17 in which the guiding element is positioned relative to the projection portion in a closed, rinsing position;

Fig. 21 shows a side view of the blood treatment machine of figure 17, in which the guiding element is positioned relative to the projection portion in the closed, rinsing position; Fig. 22 shows the blood treatment device of figure 21, wherein a container is at tached to the attachment elements of the blood treatment device;

Fig. 23 shows a sectional view illustrating the rinsing position of the guiding element relative to the projection portion;

Fig. 24 shows a perspective view of the container that is attached to the attachment elements of the blood treatment device in the closed rinsing position;

Fig. 25 shows the container connected to the blood treatment device in a position, in which the container is fluidically coupled to the blood treatment device;

Fig. 26 shows a sectional view of the arrangement of figure 25;

Fig. 27 shows a blood treatment device, to which a container is fluidically coupled;

Fig 28 shows the blood treatment device of Fig. 27 in the rinsing position.

Fig. 29 shows the guiding element and the projection portion of the blood treatment device in the closed rinsing position;

Fig. 30 shows the arrangement of figure 29, to which a container has been attached;

Fig. 31 shows the position, in that the container is fluidically coupled to the blood treatment device;

Fig. 32 shows how the container is attached to the attachment elements of the blood treatment device;

Fig. 33 illustrates how the guide element moves inwards toward the side surface of the main body of the blood treatment device to position the container in a position that it can be fluidically coupled with the connection elements of the blood treatment device;

Fig. 34 shows a position in that the connection elements of the blood treatment de vice and the connection elements of the container are aligned in a vertical direction;

Fig. 35 demonstrates how the container is moved upwards to insert the connection elements of the blood treatment device into the connection elements of the container;

Fig. 36 illustrates the position of the container fluidically connected with the blood treatment device during blood treatment;

Fig. 37 demonstrates how the container is moved downwards after the treatment has ended, to fluidically decouple the connection elements of the container from the con nection elements of the blood treatment device;

Fig. 38 shows how the container is held in a position, in that the connection elements of the blood treatment device and the container are fluidically coupled but aligned in a vertical direction;

Fig. 39 illustrates how droplets dripping from the connection elements of the blood treatment device are captured by the concentrate bag;

Fig. 40 demonstrates how after completion of the treatment the container is removed from the blood treatment device by moving the container away from a side surface of the blood treatment device;

Fig. 41 how after completion of the treatment the container is detached from the blood treatment device;

Fig. 42 demonstrates how the guiding element is then moved into the rinsing position by aligning the cavity present on the guiding element in a vertical direction with the connection elements of the blood treatment device; and Fig. 43 illustrates the guiding element in the rinsing position in that the connection elements are inserted into the rinsing cavity present in the guiding element.

Fig. 44 shows an embodiment in which the guiding element can be manually moved using a lever 21.

As shown in Figure 1 , a container 1 comprises a main body 2 configured to contain a dry and/or liquid concentrate. Furthermore, the container 1 comprises two attachment elements 3 having the form of hooks that are arranged at opposite sides of an at tachment portion 4 of the container 1.

Furthermore, the container 1 comprises connection elements 5 that are opened to wards a top end surface 6 of the connection portion 4 of the container 1 that is oppo site to / facing away from the main body 2. In this embodiment, the container also comprises a handle 22 allowing a user to grip the container 1. The top end surface 6 is sealed by a flexible film 7 that covers the connection elements 5 as well as the central opening 8 of the connection portion 4.

Figure 2 shows another container 1 according to the present invention. In this em bodiment the flexible film seals the connection element 5 but does not completely cover the central opening 8. Furthermore, in this embodiment, the attachment ele ments 3 take the form of hollow cylinders configured to receive corresponding studs / pins of a blood treatment device.

Figure 3 shows a user peeling off the flexible film 7 from the top end surface 6 of the container 1. As in all drawings, components denoted by the same reference numer als are the same or similar components.

In the state shown in Figure 4, the user has almost completely removed the flexible film 7 from the top end surface 6 of the container 1. Figure 5 shows a connection portion 4 of a concentrate container known from the prior art. Such conventional connection portions of containers known from the prior art generally comprise connection elements 5 that are opened downwards so that liquid can drip from these connection portions into connection elements present on the blood treatment device that are configured to be inserted into the connection el ements 5. The connection portion further comprises a handle 22 allowing a user to grip the connection portion.

Figure 6 shows a connection portion 4 of the container according to the present in vention. This connection portion comprises attachment elements 3 formed as hollow cylinders and configured to receive corresponding connection elements, especially in the form of studs, pins or cylinders, present on the blood treatment device.

The connection portion 4 further comprises connection elements 5 that are opened upwards towards a top end surface 6 of the connection portion.

According to this embodiment, the connection portion 4 furthermore comprises grip ping portions 8 at opposing sides of the connection portion 4 that replace the handle 22 present in the conventional connection portion shown in figure 5.

Figure 7 shows the connection portion 4 according to the prior art in a side view, showing the connection elements 5 as well as the handle 22. In comparison to that, the connection portion 4 of the container according to the present invention shown in Fig. 8 comprises attachment elements 3 arranged at opposing sides of the connec tion portion 4 and formed as hollow cylinders. The openings of the connection por tions cannot be seen in this view.

Figure 9 shows a sectional view of the connection portion 4 of figure 7 in that the handle 22 is clearly visible. In the sectional view of the connection portion 4 accord ing to the present invention in Figure 10, the gripping portions 9 are clearly visible as well as the attachment elements 3 and the connection elements 5 that are opened towards a top end surface 6 of the connection portion 4. As can be seen from Figure 11 , the connection elements 5 of the connection portion

4 according to the prior art also function as attachment elements, because the con nection elements 5 in the form of hollow cylinders are arranged over corresponding spouts of the blood treatment device.

This is further illustrated in the view of Figure 12, from that it can be seen that at tachment elements of the blood treatment device, i.e. connection elements of a blood treatment device according to the prior art are inserted into the connection elements

5 of the connection portion 4 in an essentially vertical position/direction in Figure 12, thereby allowing liquid from the connection elements 5 to drip out of the connection elements 5 of the connection portion 4 of a container 1.

As shown in Figure 13, according to the present invention, the attachment elements 3 and the connection elements 5 are separate from each other. From Figure 13 it can also be easily seen, that the attachment elements 3 and the connection elements 5 are arranged relative to each other in that they project along directions that are es sentially arranged at right angles to each other, preferably horizontally and vertically respectively.

In the example of Figure 13, the attachment elements project in a direction from the top of figure 13 to the bottom of figure 13 whereas the connection elements 5 are openings projecting or extending in the direction into and out of the paper plane.

Figure 14 provides another clear view of the gripping portion 9, that can substitute the handle 22 present in connection portions 4 known from the prior art.

Figure 15 further illustrates how the direction of extension of the attachment elements 3 is arranged essentially at right angles to the direction of extension of the connection elements/openings 5.

As can be seen in Figure 16, the connection elements 5 are preferentially sealed off by the flexible strip 7 that is preferentially welded to the top end surface 6 of the con nection portion 4 to close the connection elements 5. Preferentially, the flexible film 7 comprises a gripping section 10 that allows the user to grip the flexible film 7 to remove the flexible film 7 from the top end surface 6 of the connection portion 4 of container 1.

As can be seen in Figure 17, a blood treatment device 11 according to the present invention includes a main body 12 that has a bottom surface 13 and a attachment assembly 14 configured for attaching to and connecting to the container 1.

The attachment assembly 14 comprises a guiding element 15 to which two attach ment elements 16 are mounted that in this embodiment have the form of protruding cylinders / studs / pins each having a circumferential groove into which the hooks or hook-shaped attachment elements 3 of a container 1 can be inserted.

The attachment assembly 14 furthermore comprises a projection portion 17. In the configuration shown in Figure 17, a front surface 18 of the projection portion 17 and front surface 19 of the guiding element 15 are aligned with each other to form a con tinuous front surface of the attachment assembly 14. This corresponds to the rinsing position.

As can be seen in Figure 18, a bag 1 can be attached by means of hook shaped at tachment elements 3 onto the stud-shaped attachment elements 16 mounted onto the guiding element 15.

Figure 19 shows the blood treatment device 11 with a container 1 attached to the attachment elements 16 of the guiding element 15. The container 1 is in a position in which it is fluidically coupled to the blood treatment device.

Figure 20 shows the attachment assembly 14 of a blood treatment device 11 in that the guiding element 15 is arranged relative to the projection portion 17 in a closed position used for rinsing the blood treatment device.

In this position, a front surface 18 of the projection portion 17 and a front surface 19 of the guiding element 15 form a continuous front surface. The rinsing position of the guiding element 15 relative to the projection portion 17 is further illustrated in a side view of the blood treatment device 11 shown in Figure 21. From this figure it be comes especially clear, that in the closed position/rinsing position of the guiding ele ment relative to the projection portion 17, the front end surface 18 of the projection portion 17 and the front end surface 19 of the guiding element 19 form a continuous front end surface.

Figure 22 shows the blood treatment device of Figure 21, with a container 1 being attached via its attachment elements 3 to the attachment elements 16 of the blood treatment device. This position is adopted when the blood treatment device is rinsed/disinfected by internal circulation but already prepared for the next blood treatment by the provision of the container 1. Prior to commencing the next blood treatment, the container 1 will be fluidically connected to the blood treatment device 11.

Figure 23 illustrates in more detail the structural configuration of the attachment as sembly 14 of the blood treatment device by providing a sectional view of the attach ment assembly 14 in the closed/rinsing position illustrated in Figures 21 and 22. As can be seen in Figure 23, the front end surfaces 18 and 19 of the projection portion 17 and the guiding element 15 provide a continuous front surface.

In this relative positioning, the connection element 20 of the blood treatment device that in the embodiment of figure 23 has the form of a spout used for dispensing water into the container 1 is inserted in a cavity 18 present in the guiding element 15. Thus, the internal fluidic system of the blood treatment device is closed off from the outside and rinsing fluid can be circulated within the blood treatment device without fluid leak ing from the spout 17 to the outside of the blood treatment device 11.

Figure 24 shows a close-up view of the connection assembly 14 of the blood treat ment device 11 to that a container 1 has been attached via the attachment elements 3 and 16. The connection assembly 14 is in the closed position/rinsing position. In order to fluidically couple the container 1 to the connection assembly 14 and thus to the blood treatment device 11, the guiding element 15 is subsequently moved in wards towards the side surface of the blood treatment device 11 , as shown in Figure 25. The container 1 attached to the attachment element 16 of the blood treatment device 11 is thus moved towards the side surface of the blood treatment device 11 until it is arranged under the projection portion 17 and the connection elements 5 of the bag 1 are horizontally aligned with the connection elements 20 of the blood treatment device.

As illustrated in Figure 26, the guiding element 15 and thus the container 1 attached to the attachment elements 16 mounted onto the guiding element 15 are moved up wards to connect the connection elements 5 of the container 1 with the connection element 20 of the blood treatment device. Alternatively the container 1 can be held stationary by the guiding element 15 and the connection elements 20 of the blood treatment device are moved downwards to be inserted into the connection elements 5 of the container 1 to thereby fluidically couple the container 1 to the blood treatment device 11.

Figure 27 shows a side view of the blood treatment device with a container 1 fluidi cally coupled to the blood treatment device 11 in that position/relative positioning shown in figure 26.

Fig. 28 shows a side view of the blood treatment device 11 with the attachment as sembly 24 being in the position shown in Fig. 24.

Figure 29 shows another view of the connection assembly 14 of the blood treatment device in the closed rinsing position.

Figure 30 shows the attachment assembly 14 of figure 29, wherein a container 1 has been attached via its attachment elements 3 (hook-shaped) and the attachment ele ments 16 (stud-shaped) of the blood treatment device. In this depiction, the attach ment assembly 14 is still in the closed rinsing position. Figure 31 shows the attachment assembly 14, wherein the container 1 has been moved inwards under the projection portion 17 and has been fluidically coupled to the blood treatment machine by inserting the connection elements of the blood treatment device into the connection elements of the container 1 , by either moving the container 1 upwards towards the projection portion 17 or by moving the connec tion elements 20 of the blood treatment device downwards into the connection ele ments 5 of the container 1.

Next, a method of connecting a container for concentrate to a blood treatment device according to the present invention will be described.

As shown in Figure 32, the attachment elements 16 of the blood treatment device are inserted into the attachment elements 3 of the container 1. As can be seen in Figure 32, the attachment elements 16 of the blood treatment device and the attachment element 3 of the container are configured asymmetrically to allow mounting of the container to the blood treatment device only in one correct mounting position.

Figure 33 shows the container 1 connected to the attachment elements 16 of the blood treatment device via the attachment elements 3 of the container. The guiding element 15 then moves inwards in a horizontal direction toward a side surface of the blood treatment device 11 to draw the container 1 under the projection portion 17, as illustrated in Figure 34.

Also from Figure 34 it can be seen that the connection elements 20 of the blood treatment device and the connection elements 5 are in this position aligned in a verti cal direction so that the connection elements 20 can be inserted into the connection elements 5 of the container 1 by movement along the vertical axis.

As shown in Figure 35, the connection elements 20 of the blood treatment device can be / are inserted into the connection elements 5 of the container 1 by moving the guiding element 15 and thus the container 1 upwards towards the projection portion 17. Alternatively, the connection elements 20 of the blood treatment device can be moved downwards to be inserted into the connection elements 5 of the container 1. When the container 1 is fluidically coupled to the blood treatment device via the con nection elements 20 and the connection elements 5 as shown in Fig. 36, treatment can be carried out by the blood treatment machine that generates the liquid concen trate from the powder concentrate contained within the main body 2 of the container 1.

After treatment has finished, the guiding element 15 and thus the container 1 at tached thereto is moved downwards, as illustrated in Figure 37. The downward movement of the container 1 is continued until the connection elements 20 of the blood treatment device are removed from the connection elements 5 of the container 1 , as illustrated in Figure 38.

The guiding element 15 and thus the container 1 attached thereto is then subse quently moved outwards in a horizontal direction similar to a drawer from the side surface of the blood treatment device 11.

As illustrated in Figure 39, the movement of the container 1 can be paused in a posi tion in which the container 1 is vertically aligned with the connection elements 20 of the blood treatment device, so that any droplets dripping from the connection ele ments 20 of the blood treatment device are caught by the container 1 , preferably the connection elements 5 of the container 1.

As shown in Figure 40, the container 1 is then moved by means of moving the guid ing element 15 relative to the projection portion 17 until the container 1 is positioned further out / away from the side surface of the blood treatment device 11 than the front edge of the projection portion 17. This allows a user to easily grab the container 1.

As shown in Figure 41 , the container 1 can easily be disconnected from the attach ment elements 16 of the blood treatment device by pulling the container 1 away from the blood treatment device 11. After the container 1 has been removed, the blood treatment machine can then move the guiding element 15 upwards and/ or inwards towards the side surface of the blood treatment device 11 until the connection elements 20 of the blood treatment device are aligned in a vertical direction with the cavity 18 of the guiding element 15, as shown in Fig. 42.

In this position, the blood treatment device can enter the closed/rinsing position. As shown in Figure 43, the guiding element 15 is moved further upwards or the connec tion elements 20 of the blood treatment device 11 are further moved downwards, to insert the connection elements 20 into the cavity 18 of the guiding element 15 to en ter the closed rinsing position.

The blood treatment machine can now be rinsed and a new concentrate bag can be attached during rinsing to the guiding element 15 by use of attachment elements 16 to commence a new treatment.

All movements of the guiding element 15 relative to the projection portion 17 can also be performed manually. For this purpose an attachment assembly 14 of a blood treatment device can comprise a lever 21 as shown in Fig. 44 or a similar structure allowing a user to manually move the guiding element relative to the projection por tion 17.

Claims

1. Container for concentrate, comprising: a main body for containing concentrate, a connection portion having a flat end surface and configured to connect the contain er to a blood treatment device, two attachment elements arranged at two opposing sides of the connection portion and configured to reversibly attach the container to two corresponding attachment elements present on a blood treatment device, and two connection elements each comprising an opening at the flat end surface of the connection portion and configured to interact with two corresponding connection el ements present on a blood treatment device to fluidically couple the container with the blood treatment device by insertion of the connection elements present on the blood treatment device into the connection elements of the container, wherein the two attachment elements project in a first direction and the two connection ele ments project in a second direction that is oriented essentially at right angles to the first direction.

2. Container according to claim 1 , wherein the second direction in that the two con nection elements project is oriented essentially in parallel to the longitudinal axis of the main body of the container and the two connection elements each have the form of a hollow cylinder opened at the flat end surface of the connection portion.

3. Container according to claim 1 or 2, wherein the attachment elements are each formed as a hook or as a hollow cylinder.

4. Container according of one of the preceding claims, wherein the two connection elements are sealed by a lid in the form of a flexible film removably attached to the flat end surface of the connection portion and wherein the flexible film can be peeled off the flat end surface of the connection portion.

5. Container according of one of the preceding claims, wherein the container com prises two attachment elements that are formed in different sizes and / or geometrical configurations to allow attachment of the container to a blood treatment device in only one defined mounting position, and / or wherein the container comprises two connection elements that are formed in different sizes and / or geometrical configura tions to allow fluidical coupling of the container to a blood treatment device in only one defined mounting position.

6. Blood treatment device, comprising a main body, two attachment elements to that corresponding attachment elements of a container for concentrate can be attached, wherein the two attachment elements are movable relative to the main body in a direction projecting essentially at right angles from a side surface of the main body, and two connection elements configured to fluidically couple the blood treatment device to a container for concentrate.

7. Blood treatment device according to claim 6, wherein the two attachment elements each have the form of a stud projecting out ward from a side surface of the main body and the two connection elements each have the form of a spout projecting in a direction essentially parallel to the side sur face of the main body.

8. Blood treatment device according to one of claims 6 or 7, wherein the two attachment elements are mounted onto a movable and / or motor ized guiding element, preferably movable in a vertical and a horizontal direction and comprising a cavity, that can be moved between a first position, in that the two con nection elements for fluidically connecting the blood treatment device to a container are received in the cavity, thereby allowing the blood treatment device to be rinsed, and a second position, in that the two connection elements are fluidically connectable or connected to a container attached to the two attachment elements of the blood treatment device.

9. Blood treatment device according to one of claims 6 to 8, wherein the two connec tion elements are movable in a direction essentially parallel to a side surface of the main body of the blood treatment device and are movable in a direction towards a bottom surface of the main body of the blood treatment device.

10. Blood treatment device according of one of claims 6 to 9, wherein the two at tachment elements are formed in different sizes and / or geometrical configurations to allow attachment of a container to the blood treatment device in only one defined mounting position and / or the two connection elements are formed in different sizes and / or geometrical configurations to allow fluidical coupling of a container to the blood treatment device in only one defined mounting position.

11. System comprising at least one container according to one of claims 1 to 5 and at least one blood treatment device according to one of claims 6 to 10, wherein prefera bly the container is reversibly attached to the blood treatment device by means of the two attachment elements present on the container interacting with the two attach ment elements present on the blood treatment device and / or the two connection elements of the blood treatment device are fluidically coupled to the two connection elements of the container.

12. Method for connecting a container for concentrate, preferably a container accord ing of one of claims 1 to 5, to a blood treatment device, preferably a blood treatment device according to one of claims 6 to 10, comprising the steps:

13. Method of claim 12, further comprising the step:

14. Method according to claim 12 or 13, wherein the blood treatment device compris es a movable and / or motorized guiding element comprising the two attachment el ements of the blood treatment device and further comprising a cavity configured to receive the two connection elements of the blood treatment device, further compris ing the step

15. Method according to one of claims 12 to 14, wherein all method steps apart from the step of reversibly attaching the container to the blood treatment device by means of the two attachment elements present on the container and the two attachment el ements present on the blood treatment device are automatically performed by the blood treatment device.