EP3990926A4 - SYSTEM AND METHOD FOR RECOVERY OF TARGET MATERIAL FROM MICROWELLS - Google Patents

SYSTEM AND METHOD FOR RECOVERY OF TARGET MATERIAL FROM MICROWELLS Download PDF

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Publication number
EP3990926A4
EP3990926A4 EP20833529.9A EP20833529A EP3990926A4 EP 3990926 A4 EP3990926 A4 EP 3990926A4 EP 20833529 A EP20833529 A EP 20833529A EP 3990926 A4 EP3990926 A4 EP 3990926A4
Authority
EP
European Patent Office
Prior art keywords
microwells
target material
material retrieval
retrieval
target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20833529.9A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3990926A1 (en
Inventor
Kalyan Handique
Swati Ranade
Vishal Sharma
Austin Payne
Sam Tuck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/867,235 external-priority patent/US10900032B2/en
Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc
Publication of EP3990926A1 publication Critical patent/EP3990926A1/en
Publication of EP3990926A4 publication Critical patent/EP3990926A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1048—General features of the devices using the transfer device for another function
    • G01N2035/1053—General features of the devices using the transfer device for another function for separating part of the liquid, e.g. filters, extraction phase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Fluid Mechanics (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP20833529.9A 2019-06-26 2020-06-19 SYSTEM AND METHOD FOR RECOVERY OF TARGET MATERIAL FROM MICROWELLS Withdrawn EP3990926A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962866726P 2019-06-26 2019-06-26
US16/867,235 US10900032B2 (en) 2019-05-07 2020-05-05 System and method for automated single cell processing
PCT/US2020/038647 WO2020263700A1 (en) 2019-06-26 2020-06-19 System and method for target material retrieval from microwells

Publications (2)

Publication Number Publication Date
EP3990926A1 EP3990926A1 (en) 2022-05-04
EP3990926A4 true EP3990926A4 (en) 2023-09-13

Family

ID=74062083

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20833529.9A Withdrawn EP3990926A4 (en) 2019-06-26 2020-06-19 SYSTEM AND METHOD FOR RECOVERY OF TARGET MATERIAL FROM MICROWELLS

Country Status (8)

Country Link
EP (1) EP3990926A4 (zh)
JP (1) JP2022539739A (zh)
KR (1) KR20220024734A (zh)
CN (1) CN113924494A (zh)
AU (1) AU2020304355B2 (zh)
CA (1) CA3138949A1 (zh)
SG (1) SG11202112150RA (zh)
WO (1) WO2020263700A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023188896A1 (ja) * 2022-03-29 2023-10-05 ソニーグループ株式会社 生体粒子解析システム、情報処理装置、及び生体粒子解析方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042832A1 (en) * 1998-02-23 1999-08-26 Bio-Nobile Oy Magnetic particle transfer device and method
WO2009076560A2 (en) * 2007-12-12 2009-06-18 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for magnetic separation of cells
US20150225714A1 (en) * 2012-06-07 2015-08-13 Hitachi High-Technologies Corporation Kit for nucleic acid extraction and a nucleic acid extractor
US20160008814A1 (en) * 2013-03-13 2016-01-14 Denovo Sciences, Inc. System and method for capturing and analyzing cells
WO2016115025A1 (en) * 2015-01-13 2016-07-21 Gilson, Inc. Adapter for sliding magnetic particle separation
US20180036731A1 (en) * 2013-03-13 2018-02-08 Denovo Sciences, Inc. System and method for capturing and analyzing cells
US20190060902A1 (en) * 2017-08-29 2019-02-28 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050106667A1 (en) * 2003-08-01 2005-05-19 Genentech, Inc Binding polypeptides with restricted diversity sequences
US8030080B2 (en) * 2006-01-18 2011-10-04 Argos Therapeutics, Inc. Systems and methods for processing samples in a closed container, and related devices
CA2757300C (en) * 2009-04-01 2018-01-09 Dxterity Diagnostics Incorporated Chemical ligation dependent probe amplification (clpa)
JP5292267B2 (ja) * 2009-12-16 2013-09-18 株式会社日立ハイテクノロジーズ 試料処理装置、試料処理方法及びこれらに使用する反応容器
JP2011234671A (ja) * 2010-05-11 2011-11-24 Hitachi High-Technologies Corp 核酸抽出装置
EP2587245A4 (en) * 2010-06-22 2017-08-30 Universal Bio Research Co., Ltd. Device for trapping biologically-relevant substances and system for collecting biologically-relevant substances
US9339812B2 (en) * 2012-02-13 2016-05-17 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
JP6745881B2 (ja) * 2015-12-01 2020-08-26 イラミーナ インコーポレーテッド 単一細胞の単離および分析物の特徴付けのためのデジタルマイクロ流体システム

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042832A1 (en) * 1998-02-23 1999-08-26 Bio-Nobile Oy Magnetic particle transfer device and method
WO2009076560A2 (en) * 2007-12-12 2009-06-18 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for magnetic separation of cells
US20150225714A1 (en) * 2012-06-07 2015-08-13 Hitachi High-Technologies Corporation Kit for nucleic acid extraction and a nucleic acid extractor
US20160008814A1 (en) * 2013-03-13 2016-01-14 Denovo Sciences, Inc. System and method for capturing and analyzing cells
US20180036731A1 (en) * 2013-03-13 2018-02-08 Denovo Sciences, Inc. System and method for capturing and analyzing cells
WO2016115025A1 (en) * 2015-01-13 2016-07-21 Gilson, Inc. Adapter for sliding magnetic particle separation
US20190060902A1 (en) * 2017-08-29 2019-02-28 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells

Also Published As

Publication number Publication date
EP3990926A1 (en) 2022-05-04
KR20220024734A (ko) 2022-03-03
JP2022539739A (ja) 2022-09-13
WO2020263700A1 (en) 2020-12-30
CN113924494A (zh) 2022-01-11
CA3138949A1 (en) 2020-12-30
SG11202112150RA (en) 2021-12-30
AU2020304355A1 (en) 2021-11-25
AU2020304355B2 (en) 2023-04-06

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