EP3823714A4 - Systems and methods for treatment of cancer using alternating electric field generation - Google Patents

Systems and methods for treatment of cancer using alternating electric field generation Download PDF

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Publication number
EP3823714A4
EP3823714A4 EP19837750.9A EP19837750A EP3823714A4 EP 3823714 A4 EP3823714 A4 EP 3823714A4 EP 19837750 A EP19837750 A EP 19837750A EP 3823714 A4 EP3823714 A4 EP 3823714A4
Authority
EP
European Patent Office
Prior art keywords
cancer
systems
treatment
methods
electric field
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19837750.9A
Other languages
German (de)
French (fr)
Other versions
EP3823714A1 (en
Inventor
Benjamin Hendricks
Kris SMITH
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dignity Health
Original Assignee
Dignity Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dignity Health filed Critical Dignity Health
Publication of EP3823714A1 publication Critical patent/EP3823714A1/en
Publication of EP3823714A4 publication Critical patent/EP3823714A4/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36135Control systems using physiological parameters
    • A61N1/36139Control systems using physiological parameters with automatic adjustment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0529Electrodes for brain stimulation
    • A61N1/0531Brain cortex electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0529Electrodes for brain stimulation
    • A61N1/0534Electrodes for deep brain stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36002Cancer treatment, e.g. tumour
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36146Control systems specified by the stimulation parameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372Arrangements in connection with the implantation of stimulators
    • A61N1/37211Means for communicating with stimulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372Arrangements in connection with the implantation of stimulators
    • A61N1/37211Means for communicating with stimulators
    • A61N1/37235Aspects of the external programmer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372Arrangements in connection with the implantation of stimulators
    • A61N1/375Constructional arrangements, e.g. casings
    • A61N1/37514Brain implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Electrotherapy Devices (AREA)
EP19837750.9A 2018-07-17 2019-07-17 Systems and methods for treatment of cancer using alternating electric field generation Pending EP3823714A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862699146P 2018-07-17 2018-07-17
PCT/US2019/042197 WO2020018662A1 (en) 2018-07-17 2019-07-17 Systems and methods for treatment of cancer using alternating electric field generation

Publications (2)

Publication Number Publication Date
EP3823714A1 EP3823714A1 (en) 2021-05-26
EP3823714A4 true EP3823714A4 (en) 2022-04-20

Family

ID=69164762

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19837750.9A Pending EP3823714A4 (en) 2018-07-17 2019-07-17 Systems and methods for treatment of cancer using alternating electric field generation

Country Status (7)

Country Link
US (2) US11565111B2 (en)
EP (1) EP3823714A4 (en)
JP (2) JP7384895B2 (en)
CN (1) CN112423836A (en)
AU (1) AU2019306571B2 (en)
CA (1) CA3104885A1 (en)
WO (1) WO2020018662A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021508533A (en) 2017-12-26 2021-03-11 ギャラリー,インコーポレイテッド Optimizing energy delivery for a variety of applications
GB2604397A (en) 2021-03-05 2022-09-07 Qv Bioelectronics Ltd Cranial Prosthetic
GB2604400A (en) 2021-03-05 2022-09-07 Qv Bioelectronics Ltd Biphasic injectable electrode
WO2023168034A1 (en) * 2022-03-03 2023-09-07 Medtronic, Inc. Electrode configurations for electric field therapy

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120203307A1 (en) * 1999-04-09 2012-08-09 Schroeppel Edward A Method and device for treating abnormal tissue growth with electrical therapy
WO2016179712A1 (en) * 2015-05-14 2016-11-17 London Health Sciences Centre Research Inc. Intratumoral modulation therapy
US20170120041A1 (en) * 2015-10-28 2017-05-04 Novocure Limited TTField Treatment with Optimization of Electrode Positions on the Head Based on MRI-Based Conductivity Measurements
WO2018057953A2 (en) * 2016-09-23 2018-03-29 Beth Isreal Deaconess Medical Center, Inc. System and methods for cancer treatment using alternating electric fields

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6340353B1 (en) * 1996-09-30 2002-01-22 Jeanne K. Pomatto Manufacture of cranial remodeling orthosis
US20050021118A1 (en) * 2000-07-13 2005-01-27 Chris Genau Apparatuses and systems for applying electrical stimulation to a patient
US7826902B2 (en) * 2006-02-24 2010-11-02 Medtronic, Inc. User interface with 2D views for configuring stimulation therapy
US20080046023A1 (en) * 2006-08-16 2008-02-21 Fischell David R Electrode switch for a brain neuropacemaker
US8364284B2 (en) * 2008-09-15 2013-01-29 Boston Scientific Neuromodulation Corporation Implantable electric stimulation system and methods of making and using
GB0821325D0 (en) * 2008-11-21 2008-12-31 Ucl Business Plc Method and apparatus for performing deep brain stimulation with an electric field
JP2012521863A (en) * 2009-03-31 2012-09-20 アンジオダイナミツクス・インコーポレイテツド System and method for treatment area estimation and interactive patient treatment planning of treatment devices
WO2010120823A2 (en) * 2009-04-13 2010-10-21 Research Foundation Of The City University Of New York Neurocranial electrostimulation models, systems, devices and methods
US9119543B2 (en) * 2009-07-30 2015-09-01 Medtronic Bakken Research Center B.V. System and method for deep brain stimulation
US8996115B2 (en) * 2011-04-07 2015-03-31 Greatbatch, Ltd. Charge balancing for arbitrary waveform generator and neural stimulation application
WO2015010682A1 (en) * 2013-07-23 2015-01-29 König Florian M Simulation and extension of natural sferics signal sequences as alternating electromagnetic field
CN107614055B (en) * 2015-05-31 2022-02-25 闭环医疗私人有限公司 Brain nerve stimulator electrode assembly
US10525267B2 (en) * 2015-06-02 2020-01-07 Battelle Memorial Institute Closed loop deep brain stimulation systems and methods
CN106823140B (en) * 2017-01-14 2023-03-03 北京品驰医疗设备有限公司 Sacral nerve stimulator capable of adjusting electric field direction

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120203307A1 (en) * 1999-04-09 2012-08-09 Schroeppel Edward A Method and device for treating abnormal tissue growth with electrical therapy
WO2016179712A1 (en) * 2015-05-14 2016-11-17 London Health Sciences Centre Research Inc. Intratumoral modulation therapy
US20170120041A1 (en) * 2015-10-28 2017-05-04 Novocure Limited TTField Treatment with Optimization of Electrode Positions on the Head Based on MRI-Based Conductivity Measurements
WO2018057953A2 (en) * 2016-09-23 2018-03-29 Beth Isreal Deaconess Medical Center, Inc. System and methods for cancer treatment using alternating electric fields

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020018662A1 *

Also Published As

Publication number Publication date
US20210308455A1 (en) 2021-10-07
AU2019306571B2 (en) 2024-06-20
EP3823714A1 (en) 2021-05-26
JP2021531090A (en) 2021-11-18
CN112423836A (en) 2021-02-26
US11565111B2 (en) 2023-01-31
CA3104885A1 (en) 2020-01-23
US20230149713A1 (en) 2023-05-18
AU2019306571A1 (en) 2021-01-21
JP7384895B2 (en) 2023-11-21
WO2020018662A1 (en) 2020-01-23
JP2023184733A (en) 2023-12-28

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