EP3694354A1 - Aerosolisable product - Google Patents

Aerosolisable product

Info

Publication number
EP3694354A1
EP3694354A1 EP18788833.4A EP18788833A EP3694354A1 EP 3694354 A1 EP3694354 A1 EP 3694354A1 EP 18788833 A EP18788833 A EP 18788833A EP 3694354 A1 EP3694354 A1 EP 3694354A1
Authority
EP
European Patent Office
Prior art keywords
aerosolisable
product
present
aerosolisable product
calcium carbonate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP18788833.4A
Other languages
German (de)
French (fr)
Other versions
EP3694354B1 (en
Inventor
Richard Hepworth
Colin Dickens
Walid Abi Aoun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nicoventures Trading Ltd
Original Assignee
British American Tobacco Investments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British American Tobacco Investments Ltd filed Critical British American Tobacco Investments Ltd
Publication of EP3694354A1 publication Critical patent/EP3694354A1/en
Application granted granted Critical
Publication of EP3694354B1 publication Critical patent/EP3694354B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24C—MACHINES FOR MAKING CIGARS OR CIGARETTES
    • A24C5/00—Making cigarettes; Making tipping materials for, or attaching filters or mouthpieces to, cigars or cigarettes
    • A24C5/01—Making cigarettes for simulated smoking devices
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/20—Devices using solid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F47/00—Smokers' requisites not otherwise provided for

Definitions

  • the present disclosure relates to an aerosolisable product, containers in which are contained the aerosolisable product and to electronic aerosol provision systems such as electronic aerosol delivery systems (e.g. e-cigarettes) incorporating said product.
  • electronic aerosol delivery systems e.g. e-cigarettes
  • Electronic vapour provision systems such as e-cigarettes generally contain a reservoir of liquid which is to be vaporised, typically containing nicotine.
  • a heater is activated to vaporise a small amount of liquid, which is therefore inhaled by the user.
  • an aerosolisable product comprising
  • the present invention further provides an aerosolisable product comprising
  • aerosolisable product is a solid form.
  • the present invention further provides an aerosolisable product comprising
  • the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
  • the present invention further provides a dosage form of an aerosolisable product, wherein the dosage form comprises
  • the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m 2 per gram of aerosol forming material present in the aerosolisable product.
  • the present invention further provides a dosage form of an aerosolisable product, wherein the dosage form comprises
  • aerosolisable product is a solid form.
  • present invention further provides a dosage form of an aerosolisable product, wherein the dosage form comprises
  • the present invention further provides a process for forming an aerosol, the process comprising the steps of:
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the total surface area of the calcium carbonate present in the aerosoiisable product is at least 25m 2 per gram of aerosol forming material present in the aerosoiisable product;
  • the present invention further provides a process for forming an aerosol, the process comprising the steps of:
  • aerosoiisable product is a solid form
  • the present invention further provides a process for forming an aerosol, the process comprising the steps of:
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosoiisable product;
  • the present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of:
  • the present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of: (i) contacting an aerosol forming material and a solid substrate material, wherein the solid substrate material is at least calcium carbonate, to form an initial mixture; and
  • aerosoiisable product is a solid form.
  • the present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of:
  • the present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of:
  • the present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of:
  • the present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of:
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
  • the present invention further provides a contained aerosolisable product comprising
  • the present invention further provides a contained aerosolisable product comprising
  • aerosolisable product is a solid form.
  • the present invention further provides a contained aerosolisable product comprising
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
  • the present invention further provides an electronic aerosol provision system comprising:
  • a power supply comprising a cell or battery for supplying power to the aerosoliser; and (iii) an aerosolisable product comprising
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m 2 per gram of aerosol forming material present in the aerosolisable product.
  • the present invention further provides an electronic aerosol provision system comprising: (i) an aerosoliser for aerosolising an aerosolisable product for inhalation by a user of the electronic aerosol provision system;
  • aerosolisable product is a solid form.
  • the present invention further provides an electronic aerosol provision system comprising: (i) an aerosoliser for aerosolising an aerosolisable product for inhalation by a user of the electronic aerosol provision system;
  • a power supply comprising a cell or battery for supplying power to the aerosoliser
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
  • the present invention provides an aerosolisable product comprising (a) an aerosol forming material; and (b) a solid substrate material, wherein the solid substrate material is at least calcium carbonate, wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m 2 per gram of aerosol forming material present in the aerosolisable product.
  • the term "aerosolisable product” refers to a combination of one or more materials, at least one of which is capable of forming a condensation aerosol following heating to an appropriate temperature. Thus, it is not necessary for all components of the aerosolisable product of the present invention to be “aerosolised”.
  • the solid products of the present invention and the substrate materials of the present invention can substantially sustain their physical shape when unsupported by external means, e.g. packaging etc. Thus, they are considered to be solid, solid-like, in solid form or in solid-like form.
  • a calcium carbonate substrate such that the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m 2 per gram of aerosol forming material present in the aerosolisable product, it is possible to form a substrate having a substantially solid form which is able to hold aerosol forming materials such as glycerol.
  • the substrate may also be used to hold an active agent, such as nicotine, and flavour which are released using heating along with the visible vapour from the aerosol forming material (e.g. glycerol or other humectants).
  • an active agent such as nicotine
  • flavour which are released using heating along with the visible vapour from the aerosol forming material
  • the aerosol forming material e.g. glycerol or other humectants.
  • binders such as CMC
  • a consumable may be formed into a small solid ⁇ 1g. Due to the size of the solid, this may be loaded into a device which may have a much smaller heater (oven) than currently known in the art.
  • a small oven is advantageous since it reduces the power consumption compared to a larger oven and also reduces the size requirement of the device.
  • the aerosolisable product being heated is a discrete unit, rather than being part of a generally continuous bulk, it liquid, less power may be required to generate a vapour.
  • the substrate used to hold the aerosol generating material will comprise chalk waste which will be easy to dispose of with little worry of environmental impact.
  • the present invention provides an aerosolisable product comprising (a) an aerosol forming material; and (b) a substrate material, wherein the substrate material is at least calcium carbonate, wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m 2 per gram of aerosol forming material present in the aerosolisable product.
  • the calcium carbonate may be present in the product in any suitable amount, provided of course that the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m 2 per gram of aerosol forming material present in the aerosolisable product.
  • calcium carbonate can have a range of specific surface areas.
  • typical calcium carbonate can have a specific surface area (according to the BET method) of around 7 to 9 m 2 /g.
  • functionalised calcium carbonates may have a specific surface area (according to the BET method) of around 70m 2 /g. Therefore, in one aspect, the calcium carbonate used in the aerosolisable product has a specific surface area of at least 5 m 2 /g based on the weight of the calcium carbonate.
  • the present invention provides an aerosolisable product comprising (a) an aerosol forming material; and (b) a solid substrate material, wherein the solid substrate material is at least calcium carbonate, wherein the aerosolisable product is a solid form.
  • the calcium carbonate may be present in the product in any suitable amount, provided of course that a solid substrate material is formed.
  • the substrate is present in an amount of at least 10 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 20 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 30 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 40 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 50 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 60 wt.% based on the aerosolisable product.
  • the substrate is present in an amount of at least 70 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 80 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 85 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 95 wt.% based on the aerosolisable product.
  • the substrate is present in an amount of no greater than 99 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of no greater than 95 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of no greater than 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of no greater than 85 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of no greater than 80 wt.% based on the aerosolisable product.
  • the substrate is present in an amount of from 10 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 20 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 30 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 40 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 50 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 60 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 70 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 80 to 90 wt.% based on the aerosolisable product.
  • the substrate may be formed wholly or in part from calcium carbonate.
  • calcium carbonate is present in an amount of at least 50 wt.% based on the substrate.
  • calcium carbonate is present in an amount of at least 60 wt.% based on the substrate.
  • calcium carbonate is present in an amount of at least 70 wt.% based on the substrate.
  • calcium carbonate is present in an amount of at least 80 wt.% based on the substrate.
  • calcium carbonate is present in an amount of at least 85 wt.% based on the substrate.
  • calcium carbonate is present in an amount of at least 90 wt.% based on the substrate.
  • calcium carbonate is present in an amount of at least 95 wt.% based on the substrate. In one aspect calcium carbonate is present in an amount of at least 99 wt.% based on the substrate.
  • the substrate material consists essentially of calcium carbonate. In one aspect the substrate material consists of calcium carbonate.
  • the calcium carbonate is present in an amount of at least 10 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 20 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 30 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 40 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 50 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 60 wt.% based on the aerosolisable product.
  • the calcium carbonate is present in an amount of at least 70 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 85 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 95 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 99 wt.% based on the aerosolisable product.
  • the calcium carbonate is present in an amount of no greater than 95 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 85 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 80 wt.% based on the aerosolisable product.
  • the calcium carbonate is present in an amount of from 10 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 20 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 30 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 40 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 50 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 90 wt.% based on the aerosolisable product.
  • the calcium carbonate is present in an amount of at least 95 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 99 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 95 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 85 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 80 wt.% based on the aerosolisable product.
  • the calcium carbonate is present in an amount of from 10 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 20 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 30 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 40 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 50 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 60 to 90 wt.% based on the aerosolisable product.
  • the calcium carbonate is present in an amount of from 70 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 80 to 90 wt.% based on the aerosolisable product.
  • the present invention further provides an aerosolisable product comprising (a) an aerosol forming material; and (b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
  • an aerosolisable product comprising (a) an aerosol forming material; and (b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
  • the one or more aerosol forming materials may be present in any suitable amount in the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 1 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 5 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 10 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 15 wt.% based on the aerosolisable product.
  • the one or more aerosol forming materials is present in a total amount of at least 20 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 25 wt.% based on the aerosolisable product.
  • the one or more aerosol forming materials is present in a total amount of from 1 to 30 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of from 5 to 30 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of from 10 to 30 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of from 15 to 30 wt.% based on the aerosolisable product.
  • the one or more aerosol forming materials is present in a total amount of from 20 to 30 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of from 25 to 30 wt.% based on the aerosolisable product.
  • the aerosolisable product comprises an aerosol forming material.
  • the aerosolisable product comprises an aerosol forming material means that the aerosolisable product contains at least one aerosol forming material.
  • References herein to an aerosol forming material may be read to relate to at least one aerosol forming material.
  • the aerosol forming material may be selected from water, polyhydric alcohols, such as glycerol, propylene glycol and triethylene glycol, for example, or esters such as triethyl citrate or triacetin, or high boiling point hydrocarbons, or non-polyols, such as glycols, sorbitol or lactic acid, for example.
  • the aerosol forming material may be selected from polyhydric alcohols, such as glycerol, propylene glycol and triethylene glycol, for example, or esters such as triethyl citrate or triacetin, or high boiling point hydrocarbons, or non-polyols, such as glycols, sorbitol or lactic acid, for example.
  • polyhydric alcohols such as glycerol, propylene glycol and triethylene glycol, for example, or esters such as triethyl citrate or triacetin, or high boiling point hydrocarbons, or non-polyols, such as glycols, sorbitol or lactic acid, for example.
  • the aerosol forming material is selected from polyhydric alcohols (such as glycerol, propylene glycol and triethylene glycol), esters (such as triethyl citrate and triacetin), high boiling point hydrocarbons, non-polyols (such as glycols, sorbitol and lactic acid), and mixtures thereof [preferably wherein the aerosol forming material is selected from glycerol, propylene glycol, and mixtures thereof].
  • polyhydric alcohols such as glycerol, propylene glycol and triethylene glycol
  • esters such as triethyl citrate and triacetin
  • high boiling point hydrocarbons such as glycols, sorbitol and lactic acid
  • non-polyols such as glycols, sorbitol and lactic acid
  • the aerosol forming material may be selected from water, triethylene glycol, triethyl citrate, triacetin, glycols, sorbitol, lactic acid, glycerol, propylene glycol, and mixtures thereof.
  • the aerosol forming material may be selected from triethylene glycol, triethyl citrate, triacetin, glycols, sorbitol, lactic acid, glycerol, propylene glycol, and mixtures thereof.
  • the aerosol forming material is selected from water, glycerol, propylene glycol, and mixtures thereof.
  • the aerosol forming material is selected from glycerol, propylene glycol, and mixtures thereof.
  • the aerosol forming material is at least water. In this aspect, a further aerosol forming material may be present or may not be present. In a further aspect, the aerosol forming material comprises water and at least one aerosol forming material other than water. In one aspect, the one or more aerosol forming materials is mixture of (a) water and (b) glycerol, propylene glycol or a mixture thereof.
  • the aerosol forming material(s) may be present in any suitable amount in the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 5 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 10 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 15 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 20 wt.% based on the aerosolisable product.
  • the aerosol forming material is present in a total amount of at least 25 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 30 wt.% based on the aerosolisable product.
  • the aerosol forming material is present in a total amount of from 5 to 30 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 10 to 30 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 15 to 30 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 20 to 30 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 25 to 30 wt.% based on the aerosolisable product.
  • the aerosol forming material is present in a total amount of from 5 to 25 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 5 to 20 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 5 to 15 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 5 to 10 wt.% based on the aerosolisable product.
  • the aerosol forming material is at least glycerol.
  • the glycerol may be present in any suitable amount in the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 5 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 10 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 15 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 20 wt.% based on the aerosolisable product.
  • the glycerol is present in a total amount of at least 25 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 5 to 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 10 to 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 15 to 30 wt.% based on the aerosolisable product.
  • the glycerol is present in a total amount of from 20 to 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 25 to 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 5 to 25 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 5 to 20 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 5 to 15 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 5 to 10 wt.% based on the aerosolisable product.
  • the aerosol forming material is at least propylene glycol.
  • the propylene glycol may be present in any suitable amount in the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 5 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 10 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 15 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 20 wt.% based on the aerosolisable product.
  • the propylene glycol is present in a total amount of at least 25 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 30 wt.% based on the aerosolisable product.
  • the propylene glycol is present in a total amount of from 5 to 30 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 10 to 30 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 15 to 30 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 20 to 30 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 25 to 30 wt.% based on the aerosolisable product.
  • the propylene glycol is present in a total amount of from 5 to 25 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 5 to 20 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 5 to 15 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 5 to 10 wt.% based on the aerosolisable product.
  • the aerosol forming material is at least water. The water may be present in any suitable amount in the aerosolisable product.
  • the water is present in a total amount of at least 5 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of at least 10 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of at least 15 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of at least 20 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of at least 25 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of at least 30 wt.% based on the aerosolisable product.
  • the water is present in a total amount of from 5 to 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 10 to 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 15 to 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 20 to 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 25 to 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 5 to 25 wt.% based on the aerosolisable product.
  • the water is present in a total amount of from 5 to 20 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 5 to 15 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 5 to 10 wt.% based on the aerosolisable product.
  • the calcium carbonate has a specific surface area (according to the BET [ Brunauer-Emmett-Teller] method) of at least 5 m 2 /g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 7 m 2 /g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of 7 to 9 m 2 /g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 70 m 2 /g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 72 m 2 /g.
  • BET Brunauer-Emmett-Teller
  • the calcium carbonate has a specific surface area (according to the BET method) of at least 80 m 2 /g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 85 m 2 /g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 90 m 2 /g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 95 m 2 /g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 100 m 2 /g. The specific surface area of the calcium carbonate may be measured in accordance with ISO 9277:2010(en) "Determination of the specific surface area of solids by gas adsorption— BET method"
  • the aerosolisable product of the present invention may contain one or more further components. These components may be selected depending on the nature of the formulation.
  • the aerosolisable product further comprises an active agent.
  • active agent it is meant an agent which has a biological effect on a subject when the vapour is inhaled.
  • the one or more active agents may be selected from nicotine, botanicals, and mixtures thereof.
  • the one or more active agents may be of synthetic or natural origin.
  • the active could be an extract from a botanical, such as from a plant in the tobacco family.
  • An example active is nicotine.
  • the active agent is at least nicotine. Nicotine may be provided at any suitable amount depending on the desired dosage to be inhaled by the user.
  • nicotine is present in an amount of no greater than 6 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to 6 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 6 wt.% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 6 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 .8 to 6 wt% based on the total weight of the aerosolisable product.
  • nicotine is present in an amount of from 0.4 to 5 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 5 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 5 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1.8 to 5 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of no greater than 4 wt% based on the total weight of the aerosolisable product.
  • nicotine is present in an amount of from 0.4 to 4 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 4 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 4 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1.8 to 4 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of no greater than 3 wt% based on the total weight of the aerosolisable product.
  • nicotine is present in an amount of from 0.4 to 3 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 3 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 3 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1.8 to 3 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of no greater than 1.9 wt% based on the total weight of the aerosolisable product.
  • nicotine is present in an amount of no greater than 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.5 to 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.5 to 1 .8 wt% based on the total weight of the aerosolisable product.
  • nicotine is present in an amount of from 0.8 to 1 .9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 1 .8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of less than 1.9 wt% based on the total weight of the aerosolisable product.
  • nicotine is present in an amount of less than 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to less than 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to less than 1 .8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.5 to less than 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.5 to less than 1.8 wt% based on the total weight of the aerosolisable product.
  • nicotine is present in an amount of from 0.8 to less than 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to less than 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to less than 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to less than 1.8 wt% based on the total weight of the aerosolisable product.
  • the product includes tobacco and/or a tobacco extract.
  • the product When the product is in a solid form, it may be formed into any suitable shape.
  • solid forms may be provided to allow for different surface areas and more airflow paths through/around the material.
  • Such shapes may be hollow centres (single or multiple holes), surface textures/channels/ridges (for less contact to hot surfaces of ovens and increased airflow around the consumable) and loose spheres/agglomerated particles which could fill different heating apparatus e.g. different shaped ovens.
  • the product When the product is in a solid form, the product is typically prepared by combining calcium carbonate with one or more liquids such as the aerosol forming material to form a material capable of being compressed into multiple solid forms.
  • a solid form of calcium carbonate may be prepared into which the liquids are introduced.
  • the present invention allows for the material to be compressed into a suitable form such as a pellet or pill form.
  • a paste like or putty like material for example containing a liquid loading between 20-30%) may be prepared.
  • This semi solid material may be delivered in any suitable manner. For example, it may be added to an aerosol generation system as a paste or putty from a tube.
  • the semi solid systems of the present invention allow for higher aerosol formation and the ability to fill different shapes.
  • the solid systems of the present invention have the advantage that they allow for clear airflow paths for drawing the vapour generated and reduce the amount of system cleaning required.
  • a putty is malleable.
  • a putty may deform but not be free flowing under gravity.
  • a putty may change shape under its own mass but under its own mass should not change shape dimensionally in any orientation by more than 10 percent over a 24 hour period.
  • the aerosolisable product may be delivered in a form which is then further contained to provide a discreet product.
  • solid product such as loose powder, particles, agglomerates, spheronised material, pills or pellets may be contained within a perforated or porous wrap.
  • This wrap is typically constructed of materials suitable for exposure to temperature ranges up to 300°C. Suitable materials are perforated metal foil, metal mesh, porous or perforated papers and fibre constructed fleece materials.
  • the use of a porous outer wrap is advantageous since it minimises direct contact with the aerosolisable product. Additionally the use of a porous outer wrap minimises the risk of dust being released and potentially being inhaled.
  • the aerosolisable product further comprises a binder.
  • the binder agents may be selected from Microcrystalline cellulose (MCC), Carboxymethyl cellulose (CMC) and mixtures thereof.
  • the binder may be provided at any suitable amount depending on the product.
  • the binder is present in a total amount of from 0.01 to 5 wt.% based on the aerosolisable product.
  • the binder is present in a total amount of from 0.1 to 5 wt.% based on the aerosolisable product.
  • the binder is present in a total amount of from 0.1 to 3 wt.% based on the aerosolisable product.
  • the binder is present in a total amount of from 0.5 to 3 wt.% based on the aerosolisable product. In one aspect the binder is present in a total amount of from 0.5 to 2 wt.% based on the aerosolisable product. In one aspect the binder is present in a total amount of from 1 to 2 wt.% based on the aerosolisable product. Dosage Form
  • the present invention further provides a dosage form of an aerosolisable nicotine product, wherein the dosage form comprises (a) active agent, such as nicotine, in an amount of 0.001 to 1 grams ; (b) an aerosol forming material; and (c) a solid substrate material, wherein the solid substrate material is at least calcium carbonate wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m 2 per gram of aerosol forming material present in the aerosolisable product.
  • the present invention further provides a dosage form of an aerosolisable product, wherein the dosage form comprises
  • the present invention further provides a dosage form of an aerosolisable nicotine product, wherein the dosage form comprises (a) active agent, such as nicotine, in an amount of 0.001 to 1 grams ; (b) an aerosol forming material; and (c) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 30 wt.% based on the aerosolisable nicotine product.
  • the active agent, such as nicotine is present in an amount of 0.001 to 0.8 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.8 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.6 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.4 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.2 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.1 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.02 to 0.1 grams.
  • the active agent, such as nicotine is present in an amount of 0.03 to 0.1 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.04 to 0.1 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.05 to 0.1 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.01 to 0.09 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.01 to 0.08 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.01 to 0.07 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.01 to 0.06 grams.
  • the dosage form may be prepared from an aerosolisable product as defined herein. Process The present invention further provides a process for forming an aerosol, the process comprising the steps of:
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m 2 per gram of aerosol forming material present in the aerosolisable product;
  • the present invention further provides a process for forming an aerosol, the process comprising the steps of:
  • aerosolisable product is a solid form
  • the present invention further provides a process for forming an aerosol, the process comprising the steps of:
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product;
  • the present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
  • the present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
  • the present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
  • the present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
  • a substrate material wherein the substrate material is at least calcium carbonate wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m 2 per gram of aerosol forming material present in the aerosolisable product.
  • the present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
  • the present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
  • the process of the present invention may comprises additional steps either before the steps listed, after the steps listed or between one or more of the steps listed.
  • configurations are envisaged in which the aerosolisable product of the present invention can be heated in line with flavour matrices such as flavour capsules or tobacco.
  • the aerosol may be passed from the aerosolisable product through the flavour or tobacco matrix which may also be heated in an independent zone.
  • the aerosolisable product may be contained or delivered by any means.
  • the present invention further provides a contained aerosolisable product comprising
  • a substrate material wherein the substrate material is at least calcium carbonate wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m 2 per gram of aerosol forming material present in the aerosolisable product.
  • the present invention provides a contained aerosolisable product comprising
  • an aerosol forming material (i) an aerosol forming material; and (ii) a solid substrate material, wherein the solid substrate material is at least calcium carbonate
  • the aerosolisable product is a solid form.
  • the present invention provides a contained aerosolisable product comprising
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
  • the container may be any suitable container, for example to allow for the storage or delivery of the aerosolisable product.
  • the container may be a single dose pack or may be a multi dose pack.
  • the container may be a blister pack or may be a dispenser.
  • the container is configured for engagement with an electronic vapour provision system.
  • the container may be configured to become fluidly in communication with an electronic vapour provision system so that aerosolisable product may be delivered to the electronic vapour provision system.
  • the present disclosure relates to a container which may be used in an electronic vapour provision system, such as an e- cigarette. Throughout the following description the term "e-cigarette” is used; however, this term may be used interchangeably with electronic vapour provision system.
  • the container of the present invention is typically provided for the delivery of an aerosolisable product to or within an e-cigarette.
  • the aerosolisable product may be held within an e-cigarette or may be sold as a separate container for subsequent use with or in an e-cigarette.
  • e-cigarettes may contain a unit known as a detachable cartomiser which typically comprises a reservoir of aerosolisable product, a wick material and a device for vaporising the aerosolisable product.
  • the cartomiser is part of a single-piece device and is not detachable.
  • the container is a cartomiser or is part of a cartomiser.
  • the container is not a cartomiser or part of a cartomiser and is a container, such as a tank, which may be used to deliver aerosolisable product to or within an e-cigarette.
  • the container is part of an e-cigarette.
  • the present invention further provides an electronic aerosol provision system comprising: (i) an aerosoliser for aerosolising an aerosolisable product for inhalation by a user of the electronic aerosol provision system;
  • a power supply comprising a cell or battery for supplying power to the aerosoliser
  • the present invention provides an electronic aerosol provision system comprising:
  • a power supply comprising a cell or battery for supplying power to the aerosoliser; and (iii) an aerosolisable product comprising
  • aerosolisable product is a solid form.
  • an electronic aerosol provision system comprising:
  • a power supply comprising a cell or battery for supplying power to the aerosoliser
  • a substrate material wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
  • Microcrystalline cellulose Avicel® PH Microcrystalline Cellulose
  • the specific surface area of the calcium carbonate may be measured in accordance with ISO 9277:2010(en) "Determination of the specific surface area of solids by gas adsorption— BET method"
  • Pellets were prepared according to Samples S19 and S20 and were placed in an oven based vaporiser (Vicod 5G, http://www.atmosrx.comA icod-5G. html) to assess the ability of each product to generate an aerosol. Three repetitions were carried out for each sample. Two tests were run whereby for the first test, pellets were inserted into the device with the oven already at 200°C (results of Table 3), and for the second test, pellets were inserted into the device and then the oven was heated to 200°C. Airflow was drawn through the device whilst it was turned on and any resulting aerosol captured on a Cambridge Filter Pad (CFP). The CFP (and holder) was weighed before and after the test to check the mass change which is indicative of aerosol formation from the aerosolisable product.
  • Vicod 5G http://www.atmosrx.comA icod-5G. html

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un produit destiné à un aérosol comprenant (a) un matériau formant un aérosol ; et (b) un matériau de substrat, le matériau de substrat étant au moins du carbonate de calcium ; l'aire de surface totale du carbonate de calcium présent dans le produit destiné à un aérosol étant d'au moins 25 m2 par gramme de matériau formant un aérosol présent dans le produit destiné à un aérosol. L'invention concerne également un produit destiné à un aérosol comprenant (a) un matériau formant un aérosol ; et (b) un matériau de substrat solide, le matériau de substrat solide étant au moins du carbonate de calcium tel que le produit destiné à un aérosol étant une forme solide. L'invention concerne également un produit destiné à un aérosol comprenant (a) un matériau formant un aérosol ; et (b) un matériau de substrat, le matériau de substrat étant au moins du carbonate de calcium ; le carbonate de calcium étant présent dans une quantité d'au moins 80 % en poids sur la base du produit destiné à un aérosol.The invention relates to a product for an aerosol comprising (a) an aerosol forming material; and (b) a substrate material, the substrate material being at least calcium carbonate; the total surface area of the calcium carbonate present in the aerosol product being at least 25 m 2 per gram of aerosol-forming material present in the aerosol product. The invention also relates to a product for an aerosol comprising (a) an aerosol forming material; and (b) a solid substrate material, the solid substrate material being at least calcium carbonate such that the aerosol product is a solid form. The invention also relates to a product for an aerosol comprising (a) an aerosol forming material; and (b) a substrate material, the substrate material being at least calcium carbonate; the calcium carbonate being present in an amount of at least 80% by weight based on the product intended for an aerosol.

Description

AEROSOLISABLE PRODUCT
FIELD OF THE INVENTION The present disclosure relates to an aerosolisable product, containers in which are contained the aerosolisable product and to electronic aerosol provision systems such as electronic aerosol delivery systems (e.g. e-cigarettes) incorporating said product.
BACKGROUND TO THE INVENTION
Electronic vapour provision systems such as e-cigarettes generally contain a reservoir of liquid which is to be vaporised, typically containing nicotine. When a user inhales on the device, a heater is activated to vaporise a small amount of liquid, which is therefore inhaled by the user.
The use of e-cigarettes in the UK has grown rapidly, and it has been estimated that there are now almost three million people using them in the UK.
Current vaping products use liquids which are wicked to a heater that generates an aerosol, and this aerosol delivers nicotine and flavour. Current e-cigarette formulations typically utilise glycerol and/or propylene glycol as the liquid. In these systems, liquid can leak both in the device and in the bottles during storage and handling. Additionally, users of combustible cigarettes are accustomed to "punctuated" patterns of use, whereby successive sessions are punctuated by the exhaustion of the combustible cigarette. Consumers wishing to transition to using liquid based systems may experience a more continuous profile of use since such liquid based systems typically provide a longer lasting substrate source which spans the period associated with many conventional punctuated sessions. As a result, users may struggle to transition to the non-punctuated session of use which long lasting liquid systems deliver.
SUMMARY OF THE INVENTION
In one aspect there is provided an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate;
wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product. The present invention further provides an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a solid substrate material, wherein the solid substrate material is at least calcium carbonate,
wherein the aerosolisable product is a solid form.
The present invention further provides an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate;
wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
The present invention further provides a dosage form of an aerosolisable product, wherein the dosage form comprises
(a) active agent in an amount of 0.001 to 1 grams;
(b) an aerosol forming material; and
(c) a substrate material, wherein the substrate material is at least calcium carbonate;
wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product.
The present invention further provides a dosage form of an aerosolisable product, wherein the dosage form comprises
(a) active agent in an amount of 0.001 to 1 grams;
(b) an aerosol forming material; and
(c) a solid substrate material, wherein the solid substrate material is at least calcium carbonate;
wherein the aerosolisable product is a solid form. The present invention further provides a dosage form of an aerosolisable product, wherein the dosage form comprises
(a) active agent in an amount of 0.001 to 1 grams;
(b) an aerosol forming material; and
(c) a substrate material, wherein the substrate material is at least calcium carbonate;
wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable nicotine product. The present invention further provides a process for forming an aerosol, the process comprising the steps of:
(i) providing an aerosoiisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the total surface area of the calcium carbonate present in the aerosoiisable product is at least 25m2 per gram of aerosol forming material present in the aerosoiisable product;
(ii) heating the aerosoiisable product. The present invention further provides a process for forming an aerosol, the process comprising the steps of:
(i) providing an aerosoiisable product comprising
(a) an aerosol forming material; and
(b) a solid substrate material, wherein the solid substrate material is at least calcium carbonate;
wherein the aerosoiisable product is a solid form;
(ii) heating the aerosoiisable product.
The present invention further provides a process for forming an aerosol, the process comprising the steps of:
(i) providing an aerosoiisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosoiisable product;
(ii) heating the aerosoiisable product.
The present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a substrate material, wherein the substrate material is at least calcium carbonate, to form an initial mixture, wherein the total surface area of the calcium carbonate present in the aerosoiisable product is at least 25m2 per gram of aerosol forming material present in the aerosoiisable product; and
(ii) processing the initial mixture to form the aerosoiisable product.
The present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of: (i) contacting an aerosol forming material and a solid substrate material, wherein the solid substrate material is at least calcium carbonate, to form an initial mixture; and
(ii) processing the initial mixture to form the aerosoiisable product
wherein the aerosoiisable product is a solid form.
The present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a substrate material, wherein the substrate material is at least calcium carbonate, to form an initial mixture, wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosoiisable product; and
(ii) processing the initial mixture to form the aerosoiisable product.
The present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a solid substrate material, wherein the solid substrate material is at least calcium carbonate, to form an initial mixture; and
(ii) compressing the initial mixture to form an aerosoiisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate wherein the total surface area of the calcium carbonate present in the aerosoiisable product is at least 25m2 per gram of aerosol forming material present in the aerosoiisable product. The present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a solid substrate material, wherein the solid substrate material is at least calcium carbonate, to form an initial mixture; and
(ii) compressing the initial mixture to form an aerosoiisable product comprising
(a) an aerosol forming material; and
(b) a solid substrate material, wherein the solid substrate material is at least calcium wherein the aerosoiisable product is a solid form.
The present invention further provides a process for preparing an aerosoiisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a solid substrate material, wherein the solid substrate material is at least calcium carbonate, to form an initial mixture; and (ii) compressing the initial mixture to form an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
The present invention further provides a contained aerosolisable product comprising
(a) a container; and
(b) an aerosolisable product comprising
(i) an aerosol forming material; and
(ii) a substrate material, wherein the substrate material is at least calcium carbonate wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product. The present invention further provides a contained aerosolisable product comprising
(a) a container; and
(b) an aerosolisable product comprising
(i) an aerosol forming material; and
(ii) a solid substrate material, wherein the solid substrate material is at least calcium carbonate
wherein the aerosolisable product is a solid form.
The present invention further provides a contained aerosolisable product comprising
(a) a container; and
(b) an aerosolisable product comprising
(i) an aerosol forming material; and
(ii) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
The present invention further provides an electronic aerosol provision system comprising:
(i) an aerosoliser for aerosolising an aerosolisable product for inhalation by a user of the electronic aerosol provision system;
(ii) a power supply comprising a cell or battery for supplying power to the aerosoliser; and (iii) an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product.
The present invention further provides an electronic aerosol provision system comprising: (i) an aerosoliser for aerosolising an aerosolisable product for inhalation by a user of the electronic aerosol provision system;
(ii) a power supply comprising a cell or battery for supplying power to the aerosoliser; and (Hi) an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a solid substrate material, wherein the solid substrate material is at least calcium carbonate
wherein the aerosolisable product is a solid form.
The present invention further provides an electronic aerosol provision system comprising: (i) an aerosoliser for aerosolising an aerosolisable product for inhalation by a user of the electronic aerosol provision system;
(ii) a power supply comprising a cell or battery for supplying power to the aerosoliser; and
(iii) an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
DETAILED DESCRIPTION
As discussed herein the present invention provides an aerosolisable product comprising (a) an aerosol forming material; and (b) a solid substrate material, wherein the solid substrate material is at least calcium carbonate, wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product.
In this regard, the term "aerosolisable product" refers to a combination of one or more materials, at least one of which is capable of forming a condensation aerosol following heating to an appropriate temperature. Thus, it is not necessary for all components of the aerosolisable product of the present invention to be "aerosolised".
The solid products of the present invention and the substrate materials of the present invention can substantially sustain their physical shape when unsupported by external means, e.g. packaging etc. Thus, they are considered to be solid, solid-like, in solid form or in solid-like form. We have found that by use of a calcium carbonate substrate such that the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product, it is possible to form a substrate having a substantially solid form which is able to hold aerosol forming materials such as glycerol. As a result, problems associated with leakage and user acceptance of the prior art may be overcome. The substrate may also be used to hold an active agent, such as nicotine, and flavour which are released using heating along with the visible vapour from the aerosol forming material (e.g. glycerol or other humectants). By controlling the surface area of the calcium carbonate relative to the amount of aerosol forming material present in the aerosolisable product it is possible to avoid the issues of leakage and also create a single session for vaping which ends when the aerosolisable product runs out of aerosol forming material (since this then necessitates a change of the entire aerosolisable product).
Due to the material properties, it is possible through compression and if required the addition of binders (such as CMC) to form a consumable which may be handled as a solid in a pill/pellet/small particle (balls/agglomerated) form.
Due to the size required for a single session of vaping (8-10 puffs), a consumable may be formed into a small solid <1g. Due to the size of the solid, this may be loaded into a device which may have a much smaller heater (oven) than currently known in the art. A small oven is advantageous since it reduces the power consumption compared to a larger oven and also reduces the size requirement of the device. Further, since the aerosolisable product being heated is a discrete unit, rather than being part of a generally continuous bulk, it liquid, less power may be required to generate a vapour. Also, after use, the substrate used to hold the aerosol generating material will comprise chalk waste which will be easy to dispose of with little worry of environmental impact.
For ease of reference, these and further aspects of the present invention are now discussed under appropriate section headings. However, the teachings under each section are not necessarily limited to each particular section. Calcium Carbonate
As discussed herein the present invention provides an aerosolisable product comprising (a) an aerosol forming material; and (b) a substrate material, wherein the substrate material is at least calcium carbonate, wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product. In this aspect of the present invention, the calcium carbonate may be present in the product in any suitable amount, provided of course that the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product.
In this regard, it is noted that calcium carbonate can have a range of specific surface areas. For example, typical calcium carbonate can have a specific surface area (according to the BET method) of around 7 to 9 m2/g. However, it is possible to "functionalise" the calcium carbonate such that its surface area is increased. Indeed, functionalised calcium carbonates may have a specific surface area (according to the BET method) of around 70m2/g. Therefore, in one aspect, the calcium carbonate used in the aerosolisable product has a specific surface area of at least 5 m2/g based on the weight of the calcium carbonate. As discussed herein the present invention provides an aerosolisable product comprising (a) an aerosol forming material; and (b) a solid substrate material, wherein the solid substrate material is at least calcium carbonate, wherein the aerosolisable product is a solid form. In this aspect of the present invention, the calcium carbonate may be present in the product in any suitable amount, provided of course that a solid substrate material is formed.
In one aspect the substrate is present in an amount of at least 10 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 20 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 30 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 40 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 50 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 60 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 70 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 80 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 85 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of at least 95 wt.% based on the aerosolisable product.
In one aspect the substrate is present in an amount of no greater than 99 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of no greater than 95 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of no greater than 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of no greater than 85 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of no greater than 80 wt.% based on the aerosolisable product.
In one aspect the substrate is present in an amount of from 10 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 20 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 30 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 40 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 50 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 60 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 70 to 90 wt.% based on the aerosolisable product. In one aspect the substrate is present in an amount of from 80 to 90 wt.% based on the aerosolisable product.
The substrate may be formed wholly or in part from calcium carbonate. In one aspect calcium carbonate is present in an amount of at least 50 wt.% based on the substrate. In one aspect calcium carbonate is present in an amount of at least 60 wt.% based on the substrate. In one aspect calcium carbonate is present in an amount of at least 70 wt.% based on the substrate. In one aspect calcium carbonate is present in an amount of at least 80 wt.% based on the substrate. In one aspect calcium carbonate is present in an amount of at least 85 wt.% based on the substrate. In one aspect calcium carbonate is present in an amount of at least 90 wt.% based on the substrate. In one aspect calcium carbonate is present in an amount of at least 95 wt.% based on the substrate. In one aspect calcium carbonate is present in an amount of at least 99 wt.% based on the substrate. In one aspect the substrate material consists essentially of calcium carbonate. In one aspect the substrate material consists of calcium carbonate.
In one aspect the calcium carbonate is present in an amount of at least 10 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 20 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 30 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 40 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 50 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 60 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 70 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 85 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 95 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 99 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 95 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 85 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 80 wt.% based on the aerosolisable product.
In one aspect the calcium carbonate is present in an amount of from 10 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 20 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 30 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 40 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 50 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of at least 95 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 99 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 95 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 85 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of no greater than 80 wt.% based on the aerosolisable product.
In one aspect the calcium carbonate is present in an amount of from 10 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 20 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 30 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 40 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 50 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 60 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 70 to 90 wt.% based on the aerosolisable product. In one aspect the calcium carbonate is present in an amount of from 80 to 90 wt.% based on the aerosolisable product.
As discussed herein the present invention further provides an aerosolisable product comprising (a) an aerosol forming material; and (b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product. Each of the above embodiments which require the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product, equally apply to this aspect of the invention.
Aerosol Forming Material
The one or more aerosol forming materials may be present in any suitable amount in the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 1 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 5 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 10 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 15 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 20 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of at least 25 wt.% based on the aerosolisable product.
In one aspect the one or more aerosol forming materials is present in a total amount of from 1 to 30 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of from 5 to 30 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of from 10 to 30 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of from 15 to 30 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of from 20 to 30 wt.% based on the aerosolisable product. In one aspect the one or more aerosol forming materials is present in a total amount of from 25 to 30 wt.% based on the aerosolisable product.
As discussed herein, the aerosolisable product comprises an aerosol forming material. As will be appreciated by one skilled in the art, that the aerosolisable product comprises an aerosol forming material means that the aerosolisable product contains at least one aerosol forming material. References herein to an aerosol forming material may be read to relate to at least one aerosol forming material. The aerosol forming material may be selected from water, polyhydric alcohols, such as glycerol, propylene glycol and triethylene glycol, for example, or esters such as triethyl citrate or triacetin, or high boiling point hydrocarbons, or non-polyols, such as glycols, sorbitol or lactic acid, for example. The aerosol forming material may be selected from polyhydric alcohols, such as glycerol, propylene glycol and triethylene glycol, for example, or esters such as triethyl citrate or triacetin, or high boiling point hydrocarbons, or non-polyols, such as glycols, sorbitol or lactic acid, for example. In one aspect, the aerosol forming material is selected from polyhydric alcohols (such as glycerol, propylene glycol and triethylene glycol), esters (such as triethyl citrate and triacetin), high boiling point hydrocarbons, non-polyols (such as glycols, sorbitol and lactic acid), and mixtures thereof [preferably wherein the aerosol forming material is selected from glycerol, propylene glycol, and mixtures thereof].
The aerosol forming material may be selected from water, triethylene glycol, triethyl citrate, triacetin, glycols, sorbitol, lactic acid, glycerol, propylene glycol, and mixtures thereof. The aerosol forming material may be selected from triethylene glycol, triethyl citrate, triacetin, glycols, sorbitol, lactic acid, glycerol, propylene glycol, and mixtures thereof. In one aspect, the aerosol forming material is selected from water, glycerol, propylene glycol, and mixtures thereof. In one aspect, the aerosol forming material is selected from glycerol, propylene glycol, and mixtures thereof. In one aspect the aerosol forming material is at least water. In this aspect, a further aerosol forming material may be present or may not be present. In a further aspect, the aerosol forming material comprises water and at least one aerosol forming material other than water. In one aspect, the one or more aerosol forming materials is mixture of (a) water and (b) glycerol, propylene glycol or a mixture thereof.
The aerosol forming material(s) may be present in any suitable amount in the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 5 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 10 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 15 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 20 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 25 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of at least 30 wt.% based on the aerosolisable product.
In one aspect the aerosol forming material is present in a total amount of from 5 to 30 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 10 to 30 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 15 to 30 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 20 to 30 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 25 to 30 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 5 to 25 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 5 to 20 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 5 to 15 wt.% based on the aerosolisable product. In one aspect the aerosol forming material is present in a total amount of from 5 to 10 wt.% based on the aerosolisable product.
As discussed herein, in one aspect the aerosol forming material is at least glycerol. The glycerol may be present in any suitable amount in the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 5 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 10 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 15 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 20 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 25 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of at least 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 5 to 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 10 to 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 15 to 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 20 to 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 25 to 30 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 5 to 25 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 5 to 20 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 5 to 15 wt.% based on the aerosolisable product. In one aspect the glycerol is present in a total amount of from 5 to 10 wt.% based on the aerosolisable product.
As discussed herein, in one aspect the aerosol forming material is at least propylene glycol. The propylene glycol may be present in any suitable amount in the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 5 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 10 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 15 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 20 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 25 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of at least 30 wt.% based on the aerosolisable product.
In one aspect the propylene glycol is present in a total amount of from 5 to 30 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 10 to 30 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 15 to 30 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 20 to 30 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 25 to 30 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 5 to 25 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 5 to 20 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 5 to 15 wt.% based on the aerosolisable product. In one aspect the propylene glycol is present in a total amount of from 5 to 10 wt.% based on the aerosolisable product. As discussed herein, in one aspect the aerosol forming material is at least water. The water may be present in any suitable amount in the aerosolisable product. In one aspect the water is present in a total amount of at least 5 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of at least 10 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of at least 15 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of at least 20 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of at least 25 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of at least 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 5 to 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 10 to 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 15 to 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 20 to 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 25 to 30 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 5 to 25 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 5 to 20 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 5 to 15 wt.% based on the aerosolisable product. In one aspect the water is present in a total amount of from 5 to 10 wt.% based on the aerosolisable product.
Surface area of solid substrate per gram of aerosol forming material As has been explained above, it has been found that by controlling the surface area of the calcium carbonate relative to the amount of aerosol forming material present in the aerosolisable product it is possible to avoid the issues of leakage (since a substantially solid aerosolisable product is formed) and also create a single session for vaping which ends when the aerosolisable product runs out of aerosol forming material.
In one aspect, the calcium carbonate has a specific surface area (according to the BET [ Brunauer-Emmett-Teller] method) of at least 5 m2/g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 7 m2/g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of 7 to 9 m2/g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 70 m2/g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 72 m2/g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 80 m2/g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 85 m2/g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 90 m2/g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 95 m2/g. In one aspect the calcium carbonate has a specific surface area (according to the BET method) of at least 100 m2/g. The specific surface area of the calcium carbonate may be measured in accordance with ISO 9277:2010(en) "Determination of the specific surface area of solids by gas adsorption— BET method"
Aerosolisable Product
The aerosolisable product of the present invention may contain one or more further components. These components may be selected depending on the nature of the formulation. In one aspect, the aerosolisable product further comprises an active agent. By "active agent" it is meant an agent which has a biological effect on a subject when the vapour is inhaled. The one or more active agents may be selected from nicotine, botanicals, and mixtures thereof. The one or more active agents may be of synthetic or natural origin. The active could be an extract from a botanical, such as from a plant in the tobacco family. An example active is nicotine. In one aspect, the active agent is at least nicotine. Nicotine may be provided at any suitable amount depending on the desired dosage to be inhaled by the user. In one aspect nicotine is present in an amount of no greater than 6 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to 6 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 6 wt.% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 6 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 .8 to 6 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to 5 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 5 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 5 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1.8 to 5 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of no greater than 4 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to 4 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 4 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 4 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1.8 to 4 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of no greater than 3 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to 3 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 3 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 3 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1.8 to 3 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of no greater than 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of no greater than 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.5 to 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.5 to 1 .8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 1 .9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to 1 .8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of less than 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of less than 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to less than 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.4 to less than 1 .8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.5 to less than 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.5 to less than 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to less than 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 0.8 to less than 1.8 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to less than 1.9 wt% based on the total weight of the aerosolisable product. In one aspect nicotine is present in an amount of from 1 to less than 1.8 wt% based on the total weight of the aerosolisable product.
In one aspect, the product includes tobacco and/or a tobacco extract. When the product is in a solid form, it may be formed into any suitable shape. For example, solid forms may be provided to allow for different surface areas and more airflow paths through/around the material. Such shapes may be hollow centres (single or multiple holes), surface textures/channels/ridges (for less contact to hot surfaces of ovens and increased airflow around the consumable) and loose spheres/agglomerated particles which could fill different heating apparatus e.g. different shaped ovens.
When the product is in a solid form, the product is typically prepared by combining calcium carbonate with one or more liquids such as the aerosol forming material to form a material capable of being compressed into multiple solid forms. Alternatively, a solid form of calcium carbonate may be prepared into which the liquids are introduced. In either aspect, the present invention allows for the material to be compressed into a suitable form such as a pellet or pill form.
Alternatively, when higher levels of liquids are required, a paste like or putty like material (for example containing a liquid loading between 20-30%) may be prepared. This semi solid material may be delivered in any suitable manner. For example, it may be added to an aerosol generation system as a paste or putty from a tube. The semi solid systems of the present invention allow for higher aerosol formation and the ability to fill different shapes. The solid systems of the present invention have the advantage that they allow for clear airflow paths for drawing the vapour generated and reduce the amount of system cleaning required.
As will be understood by one skilled in the art, a putty is malleable. A putty may deform but not be free flowing under gravity. A putty may change shape under its own mass but under its own mass should not change shape dimensionally in any orientation by more than 10 percent over a 24 hour period.
In a further embodiment of the present invention, the aerosolisable product may be delivered in a form which is then further contained to provide a discreet product. For example, solid product such as loose powder, particles, agglomerates, spheronised material, pills or pellets may be contained within a perforated or porous wrap. This wrap is typically constructed of materials suitable for exposure to temperature ranges up to 300°C. Suitable materials are perforated metal foil, metal mesh, porous or perforated papers and fibre constructed fleece materials. The use of a porous outer wrap is advantageous since it minimises direct contact with the aerosolisable product. Additionally the use of a porous outer wrap minimises the risk of dust being released and potentially being inhaled.
In one aspect, the aerosolisable product further comprises a binder. The binder agents may be selected from Microcrystalline cellulose (MCC), Carboxymethyl cellulose (CMC) and mixtures thereof. The binder may be provided at any suitable amount depending on the product. In one aspect the binder is present in a total amount of from 0.01 to 5 wt.% based on the aerosolisable product. In one aspect the binder is present in a total amount of from 0.1 to 5 wt.% based on the aerosolisable product. In one aspect the binder is present in a total amount of from 0.1 to 3 wt.% based on the aerosolisable product. In one aspect the binder is present in a total amount of from 0.5 to 3 wt.% based on the aerosolisable product. In one aspect the binder is present in a total amount of from 0.5 to 2 wt.% based on the aerosolisable product. In one aspect the binder is present in a total amount of from 1 to 2 wt.% based on the aerosolisable product. Dosage Form
As discussed herein, the present invention further provides a dosage form of an aerosolisable nicotine product, wherein the dosage form comprises (a) active agent, such as nicotine, in an amount of 0.001 to 1 grams ; (b) an aerosol forming material; and (c) a solid substrate material, wherein the solid substrate material is at least calcium carbonate wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product.
As discussed herein, the present invention further provides a dosage form of an aerosolisable product, wherein the dosage form comprises
(a) active agent in an amount of 0.001 to 1 grams;
(b) an aerosol forming material; and
(c) a solid substrate material, wherein the solid substrate material is at least calcium carbonate;
wherein the aerosolisable product is a solid form. As discussed herein, the present invention further provides a dosage form of an aerosolisable nicotine product, wherein the dosage form comprises (a) active agent, such as nicotine, in an amount of 0.001 to 1 grams ; (b) an aerosol forming material; and (c) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 30 wt.% based on the aerosolisable nicotine product.
In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.8 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.8 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.6 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.4 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.2 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.001 to 0.1 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.02 to 0.1 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.03 to 0.1 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.04 to 0.1 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.05 to 0.1 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.01 to 0.09 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.01 to 0.08 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.01 to 0.07 grams. In one aspect the active agent, such as nicotine, is present in an amount of 0.01 to 0.06 grams. The dosage form may be prepared from an aerosolisable product as defined herein. Process The present invention further provides a process for forming an aerosol, the process comprising the steps of:
(i) providing an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product;
(ii) heating the aerosolisable product.
The present invention further provides a process for forming an aerosol, the process comprising the steps of:
(i) providing an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a solid substrate material, wherein the solid substrate material is at least calcium carbonate;
wherein the aerosolisable product is a solid form;
(ii) heating the aerosolisable product.
The present invention further provides a process for forming an aerosol, the process comprising the steps of:
(i) providing an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product;
(ii) heating the aerosolisable product.
The present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a substrate material, wherein the substrate material is at least calcium carbonate, to form an initial mixture, wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product; and (ii) processing the initial mixture to form the aerosolisable product.
The present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a solid substrate material, wherein the solid substrate material is at least calcium carbonate, to form an initial mixture; and
(ii) processing the initial mixture to form the aerosolisable product
wherein the aerosolisable product is a solid form. The present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a substrate material, wherein the substrate material is at least calcium carbonate, to form an initial mixture, wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product; and
(ii) processing the initial mixture to form the aerosolisable product.
The present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a solid substrate material, wherein the solid substrate material is at least calcium carbonate, to form an initial mixture; and
(ii) compressing the initial mixture to form an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product.
The present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a solid substrate material, wherein the solid substrate material is at least calcium carbonate, to form an initial mixture; and
(ii) compressing the initial mixture to form an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a solid substrate material, wherein the solid substrate material is at least calcium wherein the aerosolisable product is a solid form. The present invention further provides a process for preparing an aerosolisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a solid substrate material, wherein the solid substrate material is at least calcium carbonate, to form an initial mixture; and
(ii) compressing the initial mixture to form an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
The process of the present invention may comprises additional steps either before the steps listed, after the steps listed or between one or more of the steps listed. In one aspect, configurations are envisaged in which the aerosolisable product of the present invention can be heated in line with flavour matrices such as flavour capsules or tobacco. The aerosol may be passed from the aerosolisable product through the flavour or tobacco matrix which may also be heated in an independent zone. As discussed herein, it is also possible to include the tobacco (or other organic media) within the calcium carbonate containing solid substrate material of the present invention.
Further Aspects
The aerosolisable product may be contained or delivered by any means. In one aspect the present invention further provides a contained aerosolisable product comprising
(a) a container; and
(b) an aerosolisable product comprising
(i) an aerosol forming material; and
(ii) a substrate material, wherein the substrate material is at least calcium carbonate wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product.
In a further aspect the present invention provides a contained aerosolisable product comprising
(a) a container; and
(b) an aerosolisable product comprising
(i) an aerosol forming material; and (ii) a solid substrate material, wherein the solid substrate material is at least calcium carbonate
wherein the aerosolisable product is a solid form. In a further aspect the present invention provides a contained aerosolisable product comprising
(a) a container; and
(b) an aerosolisable product comprising
(i) an aerosol forming material; and
(ii) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
The container may be any suitable container, for example to allow for the storage or delivery of the aerosolisable product. For example, the container may be a single dose pack or may be a multi dose pack. The container may be a blister pack or may be a dispenser. In one aspect the container is configured for engagement with an electronic vapour provision system. The container may be configured to become fluidly in communication with an electronic vapour provision system so that aerosolisable product may be delivered to the electronic vapour provision system. As described above, the present disclosure relates to a container which may be used in an electronic vapour provision system, such as an e- cigarette. Throughout the following description the term "e-cigarette" is used; however, this term may be used interchangeably with electronic vapour provision system. As discussed herein, the container of the present invention is typically provided for the delivery of an aerosolisable product to or within an e-cigarette. The aerosolisable product may be held within an e-cigarette or may be sold as a separate container for subsequent use with or in an e-cigarette. As understood by one skilled in the art, e-cigarettes may contain a unit known as a detachable cartomiser which typically comprises a reservoir of aerosolisable product, a wick material and a device for vaporising the aerosolisable product. In some e- cigarettes, the cartomiser is part of a single-piece device and is not detachable. In one aspect the container is a cartomiser or is part of a cartomiser. In one aspect the container is not a cartomiser or part of a cartomiser and is a container, such as a tank, which may be used to deliver aerosolisable product to or within an e-cigarette.
In one aspect the container is part of an e-cigarette. In one aspect the present invention further provides an electronic aerosol provision system comprising: (i) an aerosoliser for aerosolising an aerosolisable product for inhalation by a user of the electronic aerosol provision system;
(ii) a power supply comprising a cell or battery for supplying power to the aerosoliser; and
(iii) an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product. In a further aspect the present invention provides an electronic aerosol provision system comprising:
(i) an aerosoliser for aerosolising an aerosolisable product for inhalation by a user of the electronic aerosol provision system;
(ii) a power supply comprising a cell or battery for supplying power to the aerosoliser; and (iii) an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a solid substrate material, wherein the solid substrate material is at least calcium carbonate
wherein the aerosolisable product is a solid form.
In a further aspect the present invention provides an electronic aerosol provision system comprising:
(i) an aerosoliser for aerosolising an aerosolisable product for inhalation by a user of the electronic aerosol provision system;
(ii) a power supply comprising a cell or battery for supplying power to the aerosoliser; and
(iii) an aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate; wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
The invention will now be described with reference to the following non-limiting example. jxamplfs
Samples of aerosolisable product were prepared in accordance with the details of Table 1 , Materials used were
Calcium Carbonate (CC): Pumex Calcitec, Calcitec Puro v/100 99%< 500 micron
Microcrystalline cellulose (MCC): Avicel® PH Microcrystalline Cellulose
Carboxymethyl cellulose (CMC):Carboxymethyl cellulose sodium
Functionalised Calcium Carbonate (FCC): a Calcium Carbonate product having the following properties
The specific surface area of the calcium carbonate may be measured in accordance with ISO 9277:2010(en) "Determination of the specific surface area of solids by gas adsorption— BET method"
Delivery
Pellets were prepared according to Samples S19 and S20 and were placed in an oven based vaporiser (Vicod 5G, http://www.atmosrx.comA icod-5G. html) to assess the ability of each product to generate an aerosol. Three repetitions were carried out for each sample. Two tests were run whereby for the first test, pellets were inserted into the device with the oven already at 200°C (results of Table 3), and for the second test, pellets were inserted into the device and then the oven was heated to 200°C. Airflow was drawn through the device whilst it was turned on and any resulting aerosol captured on a Cambridge Filter Pad (CFP). The CFP (and holder) was weighed before and after the test to check the mass change which is indicative of aerosol formation from the aerosolisable product.
It can be noted from the information in Tables 3 and 4 that heating the aerosolisable product inside the device 200°C led to an aerosol being generated (due to the various mass changes). Accordingly, it is clear that the present invention allows the preparation of the aerosolisable products which are less prone to leakage (owing to their solid-like nature) and which can provide users with a more punctuated experience compared to liquid based systems.
Various modifications and variations of the present invention will be apparent to those skilled in the art without departing from the scope and spirit of the invention. Although the invention has been described in connection with specific preferred embodiments, it should be understood that the invention as claimed should not be unduly limited to such specific embodiments. Indeed, various modifications of the described modes for carrying out the invention which are obvious to those skilled in chemistry or related fields are intended to be within the scope of the following claims.

Claims

1. An aerosolisable product comprising
(a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate;
wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product.
2. An aerosolisable product according to claim 1 wherein the calcium carbonate has a specific surface area (according to the BET method) of at least 5 m2/g
3. An aerosolisable product according to claim 1 or 2 wherein the calcium carbonate has a specific surface area (according to the BET method) of from 7 to 9 m2/g
4. An aerosolisable product according to claim 1 , 2 or 3 wherein the calcium carbonate has a specific surface area (according to the BET method) of at least 70 m2/g
5. An aerosolisable product comprising
(a) an aerosol forming material; and
(b) a solid substrate material, wherein the solid substrate material is at least calcium carbonate
wherein the aerosolisable product is a solid form.
6. An aerosolisable product according to claim 5 wherein the calcium carbonate is present in an amount of at least 50 wt.% based on the aerosolisable product.
7. An aerosolisable product according to claim 5 or 6 wherein the aerosol forming material is present in an amount of 1 to 30 wt.% based on the aerosolisable product.
8. An aerosolisable product according to any one of claims 5 to 7 wherein the aerosol forming material is present in an amount of 20 to 30 wt.% based on the aerosolisable product.
9. An aerosolisable product according to claim 5 or 6 wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
10 An aerosolisable product comprising (a) an aerosol forming material; and
(b) a substrate material, wherein the substrate material is at least calcium carbonate;
wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable product.
11 An aerosolisable product according to any one of claims 1 to 10 wherein the aerosol forming material is selected from water, triethylene glycol, triethyl citrate, triacetin, glycols, sorbitol, lactic acid, glycerol, propylene glycol, and mixtures thereof. The aerosol forming material may be selected from triethylene glycol, triethyl citrate, triacetin, glycols, sorbitol, lactic acid, glycerol, propylene glycol, and mixtures thereof.
12. An aerosolisable product according to any one of claims 1 to 1 1 wherein the aerosol forming material is selected from glycerol, propylene glycol and mixtures thereof.
13. An aerosolisable product according to any one of claims 1 to 12 wherein the aerosol forming material is a combination of glycerol and propylene glycol.
14. An aerosolisable product according to claim 13 further comprising water.
15. An aerosolisable product according to any one of claims 1 to 14 wherein the aerosol forming material is present in an amount of 1 to 15 wt.% based on the aerosolisable product.
16. An aerosolisable product according to any one of claims 1 to 15 wherein the calcium carbonate is present in an amount of at least 85 wt.% based on the aerosolisable product.
17. An aerosolisable product according to any one of claims 1 to 16 wherein the substrate material consists of calcium carbonate
18. An aerosolisable product according to any one of claims 1 to 17 further comprising nicotine.
19. An aerosolisable product according to claim 18 comprising nicotine in an amount of no greater than 2 w†% based on the total weight of the aerosolisable product.
20. An aerosolisable product according to claim 19 comprising nicotine in an amount of no greater than 1.8 wt% based on the total weight of the aerosolisable product.
21. A dosage form of an aerosolisable product, wherein the dosage form comprises
(a) active agent in an amount of 0.001 to 1 grams;
(b) an aerosol forming material; and
(c) a substrate material, wherein the substrate material is at least calcium carbonate;
wherein the total surface area of the calcium carbonate present in the aerosolisable product is at least 25m2 per gram of aerosol forming material present in the aerosolisable product.
22. A dosage form according to claim 21 or 19 wherein the aerosolisable nicotine product is an aerosolisable product as defined in any one of claims 2 to 4.
23. A dosage form of an aerosolisable nicotine product, wherein the dosage form comprises
(a) nicotine in an amount of 0.001 to 1 grams;
(b) an aerosol forming material; and
(c) a solid substrate material, wherein the solid substrate material is at least calcium carbonate;
wherein the aerosolisable product is a solid form.
24. A dosage form according to claim 23 wherein the aerosolisable nicotine product is an aerosolisable product as defined in any one of claims 6 to 9.
25. A dosage form of an aerosolisable nicotine product, wherein the dosage form comprises
(a) nicotine in an amount of 0.001 to 1 grams;
(b) an aerosol forming material; and
(c) a substrate material, wherein the substrate material is at least calcium carbonate;
wherein the calcium carbonate is present in an amount of at least 80 wt.% based on the aerosolisable nicotine product.
26. A dosage form according to any one of claims 21 to 25 wherein the aerosolisable nicotine product is an aerosolisable product as defined in any one of claims 1 1 to 20.
27. A process for forming an aerosol, the process comprising the steps of:
(i) providing an aerosolisable product as defined in any one of claims 1 to 20; and
(ii) heating the aerosolisable product.
28. A process for preparing an aerosolisable product, the process comprising the steps of:
(i) contacting an aerosol forming material and a solid substrate material, wherein the solid substrate material is at least calcium carbonate, to form an initial mixture; and
(ii) compressing the initial mixture to form the aerosolisable product.
29. A process according to claim 28 wherein the aerosolisable product is an aerosolisable product as defined in any one of claims 1 to 20.
30. A contained aerosolisable product comprising
(a) a container; and
(b) an aerosolisable product as defined in any one of claims 1 to 20.
31 . A contained aerosolisable product according to claim 30 wherein the container is configured for engagement with an electronic aerosol provision system.
32. An electronic aerosol provision system comprising:
(i) an aerosoliser for aerosolising an aerosolisable product for inhalation by a user of the electronic aerosol provision system;
(ii) a power supply comprising a cell or battery for supplying power to the aerosoliser; and (iii) an aerosolisable product as defined in any one of claims 1 to 20.
EP18788833.4A 2017-10-12 2018-10-10 Aerosolisable product Active EP3694354B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1716708.1A GB201716708D0 (en) 2017-10-12 2017-10-12 Aerosolisable product
PCT/GB2018/052893 WO2019073225A1 (en) 2017-10-12 2018-10-10 Aerosolisable product

Publications (2)

Publication Number Publication Date
EP3694354A1 true EP3694354A1 (en) 2020-08-19
EP3694354B1 EP3694354B1 (en) 2022-01-12

Family

ID=60419420

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18788833.4A Active EP3694354B1 (en) 2017-10-12 2018-10-10 Aerosolisable product

Country Status (8)

Country Link
US (1) US20210219595A1 (en)
EP (1) EP3694354B1 (en)
JP (1) JP6966636B2 (en)
KR (1) KR102418522B1 (en)
CN (1) CN111163655A (en)
GB (1) GB201716708D0 (en)
RU (1) RU2747524C1 (en)
WO (1) WO2019073225A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6371928B1 (en) * 2018-02-23 2018-08-08 株式会社 東亜産業 Electronic cigarette filling and electronic cigarette cartridge using the same
GB201812512D0 (en) 2018-07-31 2018-09-12 Nicoventures Holdings Ltd Aersol generation
GB201812496D0 (en) 2018-07-31 2018-09-12 Nicoventures Holdings Ltd Aerosol generation
AU2019315715B2 (en) 2018-07-31 2022-03-24 Nicoventures Trading Limited Aerosol generating substrate
GB201812509D0 (en) * 2018-07-31 2018-09-12 Nicoventures Holdings Ltd Aerosol generation
IT201800010532A1 (en) * 2018-11-23 2020-05-23 Magg Consulting S R L Improved Method for Preparing Solid Smoke Products.
US11324249B2 (en) 2019-03-06 2022-05-10 R.J. Reynolds Tobacco Company Aerosol delivery device with nanocellulose substrate
EP3811790A1 (en) 2019-10-25 2021-04-28 Nerudia Limited Flavour delivery article for a smoking substitute apparatus
JP7695239B2 (en) 2019-11-04 2025-06-18 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム Method for Producing Aerosol-Generating Elements
TW202126192A (en) * 2019-11-15 2021-07-16 瑞士商傑太日煙國際股份有限公司 Hot pressed tobacco substrate
TW202123827A (en) * 2019-11-15 2021-07-01 瑞士商傑太日煙國際股份有限公司 Crumbed tobacco substrate
GB201918973D0 (en) * 2019-12-20 2020-02-05 Nicoventures Trading Ltd Particle
CN114557472B (en) * 2022-03-14 2023-07-14 太湖集友广誉科技有限公司 Reconstituted tobacco, preparation method thereof and cigarette product
WO2025243692A1 (en) * 2024-05-24 2025-11-27 日本たばこ産業株式会社 Inorganic filler-containing sheet

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4807648A (en) * 1987-12-21 1989-02-28 Tripar Incorporated Non-burning tobacco substitute
US5101839A (en) * 1990-08-15 1992-04-07 R. J. Reynolds Tobacco Company Cigarette and smokable filler material therefor
US5105836A (en) * 1989-09-29 1992-04-21 R. J. Reynolds Tobacco Company Cigarette and smokable filler material therefor
DE69029309T2 (en) * 1989-09-29 1997-06-12 Reynolds Tobacco Co R Cigarette and its smokable filler
US5396911A (en) * 1990-08-15 1995-03-14 R. J. Reynolds Tobacco Company Substrate material for smoking articles
GB9712815D0 (en) * 1997-06-19 1997-08-20 British American Tobacco Co Smoking article and smoking material therefor
MY137772A (en) * 2001-09-01 2009-03-31 British American Tobacco Co Smoking articles and smokable filler materials therefor
WO2003041521A2 (en) * 2001-11-09 2003-05-22 Vector Tobacco Inc. Method and composition for mentholation of charcoal filtered cigarettes
WO2007012980A1 (en) * 2005-06-01 2007-02-01 Philip Morris Products S.A. Tobacco with an increased level of natural tar dilutents
ES2324739T3 (en) * 2007-06-15 2009-08-13 Omya Development Ag CALCICO CARBONATE TREATED BY SURFACE REACTION IN COMBINATION WITH HYDROPHOBIC ADSORBENT FOR WATER TREATMENT.
GB2469838A (en) * 2009-04-29 2010-11-03 British American Tobacco Co Treated tobacco
GB2469842A (en) * 2009-04-29 2010-11-03 British American Tobacco Co Aerosol generating material for a smoking article
GB201320231D0 (en) * 2013-11-15 2014-01-01 British American Tobacco Co Aerosol generating material and devices including the same
US20150335070A1 (en) * 2014-05-20 2015-11-26 R.J. Reynolds Tobacco Company Electrically-powered aerosol delivery system
KR102544327B1 (en) * 2014-09-30 2023-06-19 필립모리스 프로덕츠 에스.에이. Recovery of tobacco constituents from processing
GB201508671D0 (en) * 2015-05-20 2015-07-01 British American Tobacco Co Aerosol generating material and devices including the same
US10154689B2 (en) * 2015-06-30 2018-12-18 R.J. Reynolds Tobacco Company Heat generation segment for an aerosol-generation system of a smoking article

Also Published As

Publication number Publication date
JP6966636B2 (en) 2021-11-17
KR20200051767A (en) 2020-05-13
CN111163655A (en) 2020-05-15
GB201716708D0 (en) 2017-11-29
JP2020533003A (en) 2020-11-19
KR102418522B1 (en) 2022-07-06
EP3694354B1 (en) 2022-01-12
RU2747524C1 (en) 2021-05-06
US20210219595A1 (en) 2021-07-22
WO2019073225A1 (en) 2019-04-18

Similar Documents

Publication Publication Date Title
EP3694354A1 (en) Aerosolisable product
JP6716696B2 (en) Flavor suction device
CN107734982B (en) Cartridges and devices for aerosol generating systems
US20220022537A1 (en) Smoking substitute apparatus
RU2770448C2 (en) Encapsulated ingredients for electronic vaping apparatuses and method for manufacture thereof
WO2019018248A1 (en) Pellet substrates for vaporizing and delivering an aerosol
US20100200008A1 (en) E-Cigarette With Vitamin Infusion
US12453365B2 (en) Flavor delivery article for a smoking substitute apparatus
CA3171016C (en) Substrates for vaporizing and delivering an aerosol
EP3692815A1 (en) Flavour delivery article for a smoking substitute apparatus
JP2023120351A (en) delivery vehicle
EP3920727A1 (en) Flavour delivery article for a smoking substitute apparatus
WO2020161331A1 (en) Packaging for smoking substitute apparatus
KR102546289B1 (en) Smoking article
KR20230151448A (en) Electrically-heating type smoking articles
EP3692817A1 (en) Flavour delivery article for a smoking substitute apparatus
EP3721723A1 (en) A carrier and a method of use thereof
US20240041105A1 (en) Coolant for heat-not-burn tobacco, heat-not-burn tobacco, and electrically heated tobacco product
WO2020161321A1 (en) Smoking substitute apparatus and smoking substitute kit
WO2026022466A1 (en) Delivery systems, devices and methods
KR20230117746A (en) Flavor Fillers and Flavor Inhalers
EP3692842A1 (en) A substrate
EP3692822A1 (en) Flavour delivery article for smoking substitute apparatus

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: UNKNOWN

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20200407

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: NICOVENTURES TRADING LIMITED

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Ref document number: 602018029582

Country of ref document: DE

Free format text: PREVIOUS MAIN CLASS: A24F0047000000

Ipc: A24B0015167000

RIC1 Information provided on ipc code assigned before grant

Ipc: A24B 15/167 20200101AFI20210607BHEP

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20210804

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602018029582

Country of ref document: DE

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 1461800

Country of ref document: AT

Kind code of ref document: T

Effective date: 20220215

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG9D

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20220112

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 1461800

Country of ref document: AT

Kind code of ref document: T

Effective date: 20220112

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220512

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220412

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220412

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220413

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220512

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602018029582

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

26N No opposition filed

Effective date: 20221013

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230504

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20221031

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20221010

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20221010

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20221031

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20221031

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20221031

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20221031

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20221010

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20221010

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20181010

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220112

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20251021

Year of fee payment: 8

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20251021

Year of fee payment: 8