EP3681377A1 - Tool for measuring at least one property of a body surface and associated measurement method - Google Patents

Tool for measuring at least one property of a body surface and associated measurement method

Info

Publication number
EP3681377A1
EP3681377A1 EP18769184.5A EP18769184A EP3681377A1 EP 3681377 A1 EP3681377 A1 EP 3681377A1 EP 18769184 A EP18769184 A EP 18769184A EP 3681377 A1 EP3681377 A1 EP 3681377A1
Authority
EP
European Patent Office
Prior art keywords
measurement sensor
body surface
measurement
tool
sensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18769184.5A
Other languages
German (de)
French (fr)
Inventor
Ghislain FRANCOIS
Frédéric FLAMENT
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Publication of EP3681377A1 publication Critical patent/EP3681377A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/442Evaluating skin mechanical properties, e.g. elasticity, hardness, texture, wrinkle assessment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/443Evaluating skin constituents, e.g. elastin, melanin, water
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6814Head
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6843Monitoring or controlling sensor contact pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6844Monitoring or controlling distance between sensor and tissue

Definitions

  • the present invention relates to a tool for measuring at least one property of a body surface, comprising:
  • Such a tool is particularly intended to be placed in front of the face of a user to realistically measure physical properties of the user's skin under conditions experienced by the user daily or similar to conditions experienced by the user daily.
  • the tool is particularly intended to make a global map of the face over time, by programming measurements made at required moments in a series of measurements.
  • the tool is advantageously used to evaluate the efficiency of a cosmetic product applied on the user's skin under real or simulated living conditions.
  • the cosmetic product is for example, a cosmetic care or make-up product for the body surface. It is particularly in the form of a liquid, a gel or a powder.
  • a cosmetic product is a product as defined in EC Regulation No. 1223/2009 of the European Parliament and the Council of November 30, 2009, relating to cosmetic products.
  • a user's skin can have different properties depending on the age, sex, ethnicity and other body parameters.
  • WO2017/037352 describes a mask that the user wears daily and that makes repeated measurements over time, at different points on the body surface.
  • WO2017/037352 is permanently applied on the user's skin. It makes only one parameter acquisition type, statically, with an uncontrolled application pressure on the skin. Furthermore, the device is completely occlusive, such that it causes higher transpiration than natural transpiration. This disturbs the measurement, particularly the measurement of moisturization.
  • One purpose of the invention is to provide a tool for measuring the properties of a user's body surface that is easy to use under real or simulated living conditions of the user, and that makes use of complex evaluation protocols, the tool being slightly intrusive.
  • the invention relates to a tool of the aforementioned type, characterized in that the tool comprises, for the or each measurement sensor:
  • the tool comprising:
  • control unit able to activate the displacement actuator following a predefined measurement protocol.
  • a measurement sensor displacement actuator makes it possible to selectively control the measurement sensor to move it from a retracted position in which it does not affect the behavior of the body surface to an extended measurement position.
  • Control of the actuator by the control unit makes it possible to make measurements at selected times and following chosen protocols, particularly in terms of application pressure on the body surface.
  • the measurement sensor is chosen from among a moisturization measurement sensor, a body surface relief measurement sensor and/or a body surface shine measurement sensor and/or a body surface microcirculation measurement sensor, and/or a sensor for measuring the quantity of sebum on the skin surface, and/or a body surface color measurement sensor, and/or a body surface shine measurement sensor, and/or a sensor for measuring the biomechanical properties of the body surface, and/or a body surface melanin content measurement sensor, and/or a body surface hydric mobility measurement sensor, and/or a sensor for measuring the density and size of body surface cells.
  • the tool comprises several measurement sensors supported by the support structure, particularly more than ten measurement sensors supported by the support structure. Due to the presence of a large number of sensors supported by the support structure, the sensors possibly being activated selectively, it is possible to create a global map of the property on the face, instead of a simple point measurement in a given area. This enables a multi-scale measurement with the same resolution as point measurements made on very local areas.
  • the body surface of the user is the user's face, the support structure being able to be placed in front of the face;
  • At least one measurement sensor is intended to be placed facing the user's chin, above or below the user's chin, at least one measurement sensor being intended to be placed facing the user's cheeks, at least one measurement sensor being intended to be placed facing the user's forehead.
  • the tool is particularly suitable for measuring facial skin properties, particularly in the different regions of the facial skin, on the chin, on the cheeks, on the forehead to obtain a global map, a diagnostic, coaching, or product performance over the entire face.
  • the tool has the following characteristics:
  • the support structure comprises a perforated frame, the or each measurement sensor being extendable by means of the displacement actuator from the perforated frame.
  • the displacement actuator comprises a hydraulic cylinder, or a piezoelectric displacement mechanism connecting the perforated frame to the or to each measurement sensor.
  • the perforated frame can easily be worn by the user, minimizing disturbance on the body surface. It forms an adapted and suitable support for each measurement sensor and for the preferably mechanical actuator to displace the measurement sensor.
  • the support structure is composed of a skin
  • the displacement actuator comprises a membrane extendable from the skin, the extendable membrane supporting the measurement sensor.
  • a support structure composed of a skin, possibly associated with a membrane actuator, significantly limits the weight of the tool and provides new service functions, such as protection against external aggression and improved esthetic appearance of the skin.
  • the or each measurement sensor is connected to the displacement actuator by a connection comprising at least one degree of freedom in rotation.
  • the degree of freedom in rotation guarantees efficient and smooth application of each sensor on the body surface in the extended position.
  • control unit is able to be configured to define a predefined measurement protocol for each measurement sensor, comprising a number of displacements of the measurement sensor between the retracted position and the extended position over time, at least one timeout during which the sensor is kept in the retracted position, at least one timeout during which the sensor is kept in the extended position, a target pressure applied by the measurement sensor on the body surface and/or a target temperature of the measurement sensor on the body surface.
  • the control unit is capable of enabling the measurement on the body surface, dynamically and in a programmable manner throughout a day, by determining the measurement frequency, the measurement time, the interval between several measurements, and/or the application pressure of the sensor on the body surface.
  • the tool comprises a unit for wireless transmission of data acquired by the or each measurement sensor to a remote recovery unit and/or for transmitting measurement protocol definition data from a remote programming unit.
  • the wireless data transmission unit is able to receive programming data from the programming unit and/or transmitting data acquired by measurement sensors to a remote device for an a posteriori analysis of the measurements.
  • the invention also relates to a method for measuring at least one property of a user's body surface, comprising the following steps:
  • the method according to the invention may comprise the following feature:
  • the body surface is the user's face.
  • - figure 1 is a front view of a first measurement tool according to the invention
  • - figure 2 is a view of areas of the face that can be evaluated by the tool in figure 1 ;
  • figure 3 is a side view of the tool in figure 1 ;
  • FIG. 4 is a partial sectional view on a sagittal plane of the tool in figure 1 , the measurement sensors being in their retracted position;
  • figure 5 is a view similar to figure 4, with the measurement sensors being in their extended positions;
  • figure 6 is a diagrammatic view of the control unit of actuators associated with each measurement sensor of the tool in figure 1 ;
  • FIG 7 is a view similar to figure 3, for another tool according to the invention.
  • a first measurement tool 10 according to the invention is shown diagrammatically in figures 1 to 6.
  • the measurement tool 10 is intended to determine at least one property of a body surface 12 of a user, in a plurality of regions 14 of the body surface 12, at chosen given instants, using a predefined measurement protocol.
  • the body surface 12 is a user's facial skin.
  • the regions 14 extend across the forehead 16, at the cheeks 18 at the cheekbones and below the latter, and on the chin 20, and in the neck 22 below the chin 20.
  • the measurement tool 10 comprises a support structure 24, and a plurality of measurement sensors 26 that can be extended from the support structure 24.
  • each measurement sensor 26 it comprises a displacement actuator 28 for the measurement sensor 26, controlling displacement between a retracted position shown on figure 4, in which the measurement sensor 26 is located at a distance from the body surface 12 and an extended position shown on figure 5 in which the measurement sensor 26 is in contact with the body surface 12.
  • the measurement tool 10 also comprises a control unit 30 for each displacement actuator 28 capable of controlling each displacement actuator 28 to make measurements at given chosen instants, following the measurement protocol.
  • the support structure 24 is intended to be worn by the user during the series of measurements, for example during at least one hour, particularly during a day.
  • the support structure 24 comprises a helmet 32 represented diagrammatically on figures 5 and 6, and a perforated mask 34, intended to be placed facing and at a distance from the body surface 12 to support the measurement sensors 26. It also comprises adjustable connection elements 36 between the helmet 32 and the perforated mask 34 to adjust the position of the perforated mask 34 relative to the body surface 12.
  • the helmet 32 is placed on the user's head.
  • the perforated mask 34 comprises a plurality of beams 38, 40, 42 defining together through openings 43.
  • the perforated mask 34 thus comprises several substantially horizontal beams 38, lateral beams 40 connecting the ends of the horizontal beams 38 and a substantially vertical central beam 42.
  • the horizontal beams 38 are intended to extend in front of the forehead 16, facing the cheeks 18 at two levels, and facing the neck 22. They support each sensor 26 and the actuators 28 connecting the sensors 26 to the support structure 24.
  • the lateral beams 40 are intended to extend at the side of the face, close to the ears.
  • the vertical beam 42 is intended to extend facing the chin 20, connecting the horizontal beams 38 facing the cheeks 18 and the chin 20, with no connection with the horizontal beam 38 located facing the forehead 16.
  • the through openings 43 are located between the horizontal beams 38, the lateral beams 40 and/or the vertical beam 42.
  • a through opening 43 thus extends continuously in front of the user's eyes to limit disturbance to his field of view.
  • the area occupied by the through openings 43 is larger than the area occupied by the beams 38, 42, 40, and particularly more than 150% of the area occupied by the beams 38, 42, 40.
  • the support structure 24 is largely perforated, which very much limits non- spontaneous generation of transpiration on the body surface 12.
  • Each measurement sensor 26 is designed to measure a property of the body surface.
  • the measurement sensor 26 is capable of measuring at least one parameter among moisturization of the body surface 12, relief of the body surface 12, microcirculation of the body surface 12, the quantity of sebum on the skin surface 12, the shine of the body surface 12, the color and heterogeneity of the body surface 12, the melanin content of the body surface 12, the biomechanical properties of the body surface 12 (stiffness, elasticity, firmness), the moisture mobility of the body surface 12, the density and size of cells on the body surface 12.
  • Each measurement sensor 26 comprises a plate 44 that will be applied on the body surface 12, a detector 46 designed to measure the physical parameter once the plate 44 has been applied on the body surface 12, and a hinged connection 48 connecting the plate 44 to the displacement actuator 28.
  • the detector 46 may be a corneometer in the form of a network deposited on a chip as described in the Applicant's European Patent application EP 1 438 922, capable of determining a degree of moisturization of the body surface 12 at the measurement point.
  • the detector 46 is a non-optical sensor that can be used to obtain information about the micro-relief of the body surface 12 at the measurement point.
  • An example of such a sensor is described in the Applicant's European Patent application EP 1 177 766.
  • the detector 46 is placed on one face of the plate 44 that will come into contact with the body surface 12, opposite to the displacement actuator 28.
  • connection 48 comprises a connecting rod fitted with ball joints at its ends.
  • the connection 48 guarantees at least one degree of freedom in rotation, preferably three degrees of freedom in rotation of the plate 44 relative to the support structure 24.
  • the measurement sensor 26 is capable of coming into contact gently on the body surface 12, adapting to the local conformation of the body surface 12 and guaranteeing good contact between the detector 46 and the body surface 12.
  • the displacement actuator 28 comprises a hydraulic cylinder 50 associated with each measurement sensor 26.
  • the hydraulic cylinder 50 is fixed to a beam 38, 40, 42 of the support structure 24. It comprises a chamber 52, and a piston 54 that can be extended towards the body surface 12 from the chamber 52.
  • the measurement sensor 26 is connected to the piston 54 through the connection
  • the movement of the piston 54 can move the measurement sensor 26 from its retracted position to its extended position.
  • the adjustable connection elements 36 comprise a connection arm 53 articulated with the helmet 32. They also comprise lateral handles 55 that adjust the distance separating the perforated mask 34 from the body surface 12.
  • control unit 30 comprises a pneumatic control unit 56 to control each displacement actuator 28, a control unit 58, a memory 60 in which data received from measurements sensors 26 are stored, a wireless data transmission unit 62 designed to communicate with a remote programming unit and advantageously a battery 64.
  • the pneumatic unit 56 comprises a hydraulic fluid reservoir 66, and a plurality of pneumatic valves 68 hydraulically connected to the reservoir 66 to supply each displacement actuator 28.
  • the pneumatic unit 56 also comprises a pressure sensor 70 in the reservoir 66, a pump 72 to increase the pressure in the reservoir 66, and a leakage valve 74 designed to reduce the pressure in the reservoir 66.
  • the reservoir 66 contains a hydraulic fluid composed of a liquid, for example an oil.
  • the hydraulic fluid may be a gas.
  • each pneumatic valve 68 is electrically connected for its control to the control unit 58.
  • Each displacement actuator 28 is connected to a first pneumatic valve 68 to control extension of the piston 54 and of the measurement sensor 26 towards the extended position and a second pneumatic valve 68 to control retraction of the piston 54 and the measurement sensor 26 towards its retracted position.
  • the pressure sensor 70 is designed to measure the pressure in the reservoir 66 and to transmit this information to the control unit 58.
  • the pump 72 and the leakage valve 74 are each connected to the control unit 58 so that the control unit 58 can regulate the pressure in the reservoir 66 to a predetermined set value.
  • the control unit 58 can control each valve 68 to enable extension or retraction of a measurement sensor 26. It is capable of receiving a program to control activation of the measurement sensors 26 from a remote control unit, so that an analysis can be made using the predefined measurement protocol.
  • the control program comprises selection data for the regions 14 on the body surface 12 to be analyzed, selection data for the number of measurements to be made during the day, selection data for the time elapsed between two measurements, adjustable as a function of the time of the day, data of the amount of contact time between the measurement sensor 26 and the body surface 12, and possibly set contact pressure data to be applied by the measurement sensor 26 on the body surface 12.
  • These definition data are advantageously input in the remote programming unit and are transmitted using a wireless transmission protocol through the data transmission unit 62.
  • the wireless transmission protocol may for example be a Wifi type protocol (for example according to Standard IEEE 802.1 1 ), Bluetooth (for example according to IEEE standard 802.15-1 -2005).
  • control unit 58 can create the selective activation protocol for each measurement sensor 26, and control each displacement actuator 28 as a function of the activation protocol.
  • the memory 60 is capable of collecting data measured by each measurement sensor 26 during its application on the body surface 12.
  • the wireless data transmission unit 62 is capable of transmitting measurement data to a remote recovery unit, ready for an analysis of data measured on each region 14 of the body surface 12.
  • the analysis is made particularly as a function of time and as a function of the applied measurement protocol.
  • the battery 64 is able to provide an electrical power supply to components of the control unit 30.
  • the remote programming unit may for example be the same as the remote recovery unit.
  • Each of these units may for example be formed by a portable apparatus, such as a smartphone, a tablet or a computer.
  • the global mass of the support structure 24 supporting the measurement sensors 26 is less than 1 kg.
  • the control unit 30 advantageously fits into a container worn separately by the user.
  • the support structure 24 is placed facing the body surface 12 to be analyzed.
  • the user places the helmet 32 on his head, placing the perforated mask 34 in front of his face. He adjusts the distance locally separating the perforated mask 34 from the body surface 12 particularly by means of lateral handles 55.
  • the measurement sensors 26 are then put into their retracted position, at a distance from the body surface 12.
  • the user or a third person then activates the remote programing unit to define a measurement protocol to be followed.
  • This measurement protocol is chosen by defining regions 24 to be analyzed on the body surface 12, and particularly measurement sensors 26 to be activated selectively, the number of measurements made by each measurement sensor 26 during the day, the time elapsed between two measurements, adjustable as a function of the time of day, the contact time between the measurement sensor 26 and the body surface 12, and possibly the application pressure of the measurements sensor 26 on the body surface 12.
  • This definition may for example be made using a specific application present in the remote programming unit.
  • the application then creates definition data that are transmitted to the control unit 58 through the wireless data transmission unit 62, using a wireless transmission as defined above.
  • control unit 30 is configured to define a predefined measurement protocol for each measurement sensor 26, comprising a number of displacements of the measurement sensor 26 between the retracted position and the extended position over time, at least one timeout during which the measurement sensor 26 is kept in the retracted position, at least one timeout during which the measurement sensor 26 is kept in the extended position, a target pressure applied by the measurement sensor 26 on the body surface 12 and/or a target temperature of the measurement sensor 26 on the body surface 12.
  • control unit 58 selectively activates the displacement actuators 28 as a function of the defined protocol to selectively apply one or several measurement sensors 26 onto the body surface 12.
  • a pneumatic valve 68 to extend the piston 54 outside the chamber 52 and move the selected measurement sensor 26 from its retracted position to its extended position, position in which the selected measurement sensor 26 is applied on the body surface 12.
  • connection 48 between the piston 54 and the sensor 26 assures gentle and precise contact of the measurement sensor 26 on the body surface 12, and appropriate placement of the detector 46 in contact with the body surface 12.
  • the contact made between the measurement sensor 26 and the body surface 12 is adjustable depending on the determined protocol, for example by applying a chosen and configurable pressure.
  • the measurement sensors 26 are gathered in a group so that they can be actuated alternately, which optimizes coverage of the face without creating a steric interaction.
  • Data collected by each measurement sensor 26 are stored in the memory 60, and are transmitted to the remote recovery unit through the wireless data transmission unit 62 using a wireless transmission protocol.
  • the data are then recorded in the recovery unit or in a "cloud" type computer architecture.
  • Data are then processed by a processing application so that the measurement results can be displayed as a function of time and/or the region 14 of the body surface.
  • the analysis application enables an observation of macroscopic results on a face in three dimensions that may be the user's face or an average face reconstituted as a function of the user's ethnicity.
  • the measurement tool 10 according to the invention is particularly unobtrusive, since it leaves the body surface in its natural configuration throughout the user's day, with no occlusion. Therefore the body surface is subjected to natural variations applied to it as the environment changes over time.
  • the measurement tool 10 remains very precise because it can efficiently measure a large number of regions 14 on the body surface 12 either simultaneously or alternately, following a protocol that can very easily be defined and modified by an external programming unit.
  • the measurement method comprises a preliminary step to apply at least one cosmetic product, such as a make-up and care product, on the body surface 12.
  • the analysis step includes a determination of the impact of the cosmetic product on the measured properties, and therefore creates a quantification of the performance of the cosmetic product as a function of time when the body surface area 12 moves alive and transforms during the day.
  • Individual control of sensors according to a predefined protocol can also optimize the measured skin surface.
  • the senor is relatively large, for example in the case of a chip described above, there may not be enough room for it in the extended position.
  • Defining sensor activation sequences can help to target very precise areas, and prevent any overlap of sensors when they are extended on the skin, while allowing the measurement zones to be adjacent to each other or even to overlap.
  • the displacement actuator 28 is a piezoelectric actuator. Moreover, operation of the tool 10 is similar.
  • the support structure 24 of the measurement tool 10 is composed of a film-shaped skin 80, facing and at a distance from the body surface 12.
  • the displacement actuator 28 is then formed by an inflatable pouch 82 that comprises a membrane 84 that can be extended from the skin 80.
  • the membrane 84 carries the measurement sensor 26.
  • Inflation of the pouch 82 enables movement of the measurement sensor 26 from its retracted position to its extended position in contact with the body surface 12.
  • the skin 80 is advantageously translucent. It provides protection against external aggression (sun, wind, pollution, etc.) and visually conceals unesthetic variations (flush, heterogeneity, shine).

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • A Measuring Device Byusing Mechanical Method (AREA)
  • Casting Or Compression Moulding Of Plastics Or The Like (AREA)

Abstract

The tool (10) includes: - a support structure (24) intended to be placed facing the body surface (12) and at a distance from the body surface (12); - at least one measurement sensor (26), supported by the support structure (24), intended to be applied on the body surface (12). The tool (10) comprises the following, for the or each measurement sensor (26): - a displacement actuator (28) of the measurement sensor (26) causing displacement of the measurement sensor (26) between a retracted position in which the measurement sensor (26) is intended to be placed at a distance from the body surface (12), and an extended position in which the measurement sensor (26) is intended to come into contact with the body surface (12), - a control unit able to activate the displacement actuator (28) following a predefined measurement protocol.

Description

Tool for measuring at least one property of a body surface and associated
measurement method
The present invention relates to a tool for measuring at least one property of a body surface, comprising:
- a support structure intended to be placed facing the body surface and at a distance from it;
- at least one measurement sensor, supported by the support structure, intended to be applied on the body surface.
Such a tool is particularly intended to be placed in front of the face of a user to realistically measure physical properties of the user's skin under conditions experienced by the user daily or similar to conditions experienced by the user daily.
The tool is particularly intended to make a global map of the face over time, by programming measurements made at required moments in a series of measurements.
The tool is advantageously used to evaluate the efficiency of a cosmetic product applied on the user's skin under real or simulated living conditions.
The cosmetic product is for example, a cosmetic care or make-up product for the body surface. It is particularly in the form of a liquid, a gel or a powder.
More generally, a cosmetic product is a product as defined in EC Regulation No. 1223/2009 of the European Parliament and the Council of November 30, 2009, relating to cosmetic products.
It can be difficult to characterize the performances of a cosmetic product depending particularly on the context in which the cosmetic product is used. In particular, under real life conditions, the skin and particularly facial skin is subjected to a variety of environmental conditions, thermal stresses, artificial light, deposits of pollution, facial movements and modifications to sebum and sweat excretions, that vary significantly during the day.
Furthermore, a user's skin can have different properties depending on the age, sex, ethnicity and other body parameters.
In order to evaluate performances, WO2017/037352 describes a mask that the user wears daily and that makes repeated measurements over time, at different points on the body surface.
Such a mask does not provide full satisfaction. The mask described in WO2017/037352 is permanently applied on the user's skin. It makes only one parameter acquisition type, statically, with an uncontrolled application pressure on the skin. Furthermore, the device is completely occlusive, such that it causes higher transpiration than natural transpiration. This disturbs the measurement, particularly the measurement of moisturization.
One purpose of the invention is to provide a tool for measuring the properties of a user's body surface that is easy to use under real or simulated living conditions of the user, and that makes use of complex evaluation protocols, the tool being slightly intrusive.
For this purpose, the invention relates to a tool of the aforementioned type, characterized in that the tool comprises, for the or each measurement sensor:
- a measurement sensor displacement actuator causing displacement of the measurement sensor between a retracted position in which the measurement sensor is intended to be placed at a distance from the body surface and an extended position in which the measurement sensor is intended to come into contact with the body surface, the tool comprising:
- a control unit able to activate the displacement actuator following a predefined measurement protocol.
The presence of a measurement sensor displacement actuator makes it possible to selectively control the measurement sensor to move it from a retracted position in which it does not affect the behavior of the body surface to an extended measurement position. Control of the actuator by the control unit makes it possible to make measurements at selected times and following chosen protocols, particularly in terms of application pressure on the body surface.
The tool can have the following characteristic:
- the measurement sensor is chosen from among a moisturization measurement sensor, a body surface relief measurement sensor and/or a body surface shine measurement sensor and/or a body surface microcirculation measurement sensor, and/or a sensor for measuring the quantity of sebum on the skin surface, and/or a body surface color measurement sensor, and/or a body surface shine measurement sensor, and/or a sensor for measuring the biomechanical properties of the body surface, and/or a body surface melanin content measurement sensor, and/or a body surface hydric mobility measurement sensor, and/or a sensor for measuring the density and size of body surface cells.
The use of moisturization and microrelief measurement sensors provides precise characterization of body surface properties at selected times following chosen protocols.
According to one variant, the tool comprises several measurement sensors supported by the support structure, particularly more than ten measurement sensors supported by the support structure. Due to the presence of a large number of sensors supported by the support structure, the sensors possibly being activated selectively, it is possible to create a global map of the property on the face, instead of a simple point measurement in a given area. This enables a multi-scale measurement with the same resolution as point measurements made on very local areas.
According to alternatives:
- the body surface of the user is the user's face, the support structure being able to be placed in front of the face;
- at least one measurement sensor is intended to be placed facing the user's chin, above or below the user's chin, at least one measurement sensor being intended to be placed facing the user's cheeks, at least one measurement sensor being intended to be placed facing the user's forehead.
The tool is particularly suitable for measuring facial skin properties, particularly in the different regions of the facial skin, on the chin, on the cheeks, on the forehead to obtain a global map, a diagnostic, coaching, or product performance over the entire face.
According to one variant, the tool has the following characteristics:
- the support structure comprises a perforated frame, the or each measurement sensor being extendable by means of the displacement actuator from the perforated frame.
- the displacement actuator comprises a hydraulic cylinder, or a piezoelectric displacement mechanism connecting the perforated frame to the or to each measurement sensor.
The perforated frame can easily be worn by the user, minimizing disturbance on the body surface. It forms an adapted and suitable support for each measurement sensor and for the preferably mechanical actuator to displace the measurement sensor.
In other variants:
- the support structure is composed of a skin
- the displacement actuator comprises a membrane extendable from the skin, the extendable membrane supporting the measurement sensor.
The use of a support structure composed of a skin, possibly associated with a membrane actuator, significantly limits the weight of the tool and provides new service functions, such as protection against external aggression and improved esthetic appearance of the skin.
Advantageously, the or each measurement sensor is connected to the displacement actuator by a connection comprising at least one degree of freedom in rotation. The degree of freedom in rotation guarantees efficient and smooth application of each sensor on the body surface in the extended position.
Advantageously, the control unit is able to be configured to define a predefined measurement protocol for each measurement sensor, comprising a number of displacements of the measurement sensor between the retracted position and the extended position over time, at least one timeout during which the sensor is kept in the retracted position, at least one timeout during which the sensor is kept in the extended position, a target pressure applied by the measurement sensor on the body surface and/or a target temperature of the measurement sensor on the body surface.
The control unit is capable of enabling the measurement on the body surface, dynamically and in a programmable manner throughout a day, by determining the measurement frequency, the measurement time, the interval between several measurements, and/or the application pressure of the sensor on the body surface.
Advantageously, the tool comprises a unit for wireless transmission of data acquired by the or each measurement sensor to a remote recovery unit and/or for transmitting measurement protocol definition data from a remote programming unit.
The wireless data transmission unit is able to receive programming data from the programming unit and/or transmitting data acquired by measurement sensors to a remote device for an a posteriori analysis of the measurements.
The invention also relates to a method for measuring at least one property of a user's body surface, comprising the following steps:
- arrangement of a tool according to any of the previous claims facing the body surface, the or each measurement sensor being positioned in its retracted position at a distance from the body surface;
- activation of the displacement actuator by the control unit to move the measurement sensor from its retracted position to its extended position in which the measurement sensor is in contact with the body surface;
- measurement of at least one property of the body surface by the measurement sensor;
- control of the displacement actuator by the control unit to move the measurement sensor from its extended position to its retracted position.
The method according to the invention may comprise the following feature:
- the body surface is the user's face.
The invention will be easier to understand after reading the following description, provided solely as an example and with reference to the appended drawings, wherein:
- figure 1 is a front view of a first measurement tool according to the invention; - figure 2 is a view of areas of the face that can be evaluated by the tool in figure 1 ;
- figure 3 is a side view of the tool in figure 1 ;
- figure 4 is a partial sectional view on a sagittal plane of the tool in figure 1 , the measurement sensors being in their retracted position;
- figure 5 is a view similar to figure 4, with the measurement sensors being in their extended positions;
- figure 6 is a diagrammatic view of the control unit of actuators associated with each measurement sensor of the tool in figure 1 ;
- figure 7 is a view similar to figure 3, for another tool according to the invention. A first measurement tool 10 according to the invention is shown diagrammatically in figures 1 to 6.
The measurement tool 10 is intended to determine at least one property of a body surface 12 of a user, in a plurality of regions 14 of the body surface 12, at chosen given instants, using a predefined measurement protocol.
In this case the body surface 12 is a user's facial skin. The regions 14 extend across the forehead 16, at the cheeks 18 at the cheekbones and below the latter, and on the chin 20, and in the neck 22 below the chin 20.
With reference to figure 1 , the measurement tool 10 comprises a support structure 24, and a plurality of measurement sensors 26 that can be extended from the support structure 24.
For each measurement sensor 26, it comprises a displacement actuator 28 for the measurement sensor 26, controlling displacement between a retracted position shown on figure 4, in which the measurement sensor 26 is located at a distance from the body surface 12 and an extended position shown on figure 5 in which the measurement sensor 26 is in contact with the body surface 12.
With reference to figure 6, the measurement tool 10 also comprises a control unit 30 for each displacement actuator 28 capable of controlling each displacement actuator 28 to make measurements at given chosen instants, following the measurement protocol.
In this case the support structure 24 is intended to be worn by the user during the series of measurements, for example during at least one hour, particularly during a day.
The support structure 24 comprises a helmet 32 represented diagrammatically on figures 5 and 6, and a perforated mask 34, intended to be placed facing and at a distance from the body surface 12 to support the measurement sensors 26. It also comprises adjustable connection elements 36 between the helmet 32 and the perforated mask 34 to adjust the position of the perforated mask 34 relative to the body surface 12.
The helmet 32 is placed on the user's head. The perforated mask 34 comprises a plurality of beams 38, 40, 42 defining together through openings 43.
The perforated mask 34 thus comprises several substantially horizontal beams 38, lateral beams 40 connecting the ends of the horizontal beams 38 and a substantially vertical central beam 42.
The horizontal beams 38 are intended to extend in front of the forehead 16, facing the cheeks 18 at two levels, and facing the neck 22. They support each sensor 26 and the actuators 28 connecting the sensors 26 to the support structure 24.
The lateral beams 40 are intended to extend at the side of the face, close to the ears.
The vertical beam 42 is intended to extend facing the chin 20, connecting the horizontal beams 38 facing the cheeks 18 and the chin 20, with no connection with the horizontal beam 38 located facing the forehead 16.
The through openings 43 are located between the horizontal beams 38, the lateral beams 40 and/or the vertical beam 42. A through opening 43 thus extends continuously in front of the user's eyes to limit disturbance to his field of view.
In projection in a vertical plane perpendicular to the sagittal plane of the face, as in the drawing in figure 1 , the area occupied by the through openings 43 is larger than the area occupied by the beams 38, 42, 40, and particularly more than 150% of the area occupied by the beams 38, 42, 40.
Thus, the support structure 24 is largely perforated, which very much limits non- spontaneous generation of transpiration on the body surface 12.
Each measurement sensor 26 is designed to measure a property of the body surface. In particular, the measurement sensor 26 is capable of measuring at least one parameter among moisturization of the body surface 12, relief of the body surface 12, microcirculation of the body surface 12, the quantity of sebum on the skin surface 12, the shine of the body surface 12, the color and heterogeneity of the body surface 12, the melanin content of the body surface 12, the biomechanical properties of the body surface 12 (stiffness, elasticity, firmness), the moisture mobility of the body surface 12, the density and size of cells on the body surface 12.
Each measurement sensor 26 comprises a plate 44 that will be applied on the body surface 12, a detector 46 designed to measure the physical parameter once the plate 44 has been applied on the body surface 12, and a hinged connection 48 connecting the plate 44 to the displacement actuator 28.
For example, the detector 46 may be a corneometer in the form of a network deposited on a chip as described in the Applicant's European Patent application EP 1 438 922, capable of determining a degree of moisturization of the body surface 12 at the measurement point.
As a variant, the detector 46 is a non-optical sensor that can be used to obtain information about the micro-relief of the body surface 12 at the measurement point. An example of such a sensor is described in the Applicant's European Patent application EP 1 177 766.
The detector 46 is placed on one face of the plate 44 that will come into contact with the body surface 12, opposite to the displacement actuator 28.
In this case the connection 48 comprises a connecting rod fitted with ball joints at its ends. The connection 48 guarantees at least one degree of freedom in rotation, preferably three degrees of freedom in rotation of the plate 44 relative to the support structure 24.
Thus, the measurement sensor 26 is capable of coming into contact gently on the body surface 12, adapting to the local conformation of the body surface 12 and guaranteeing good contact between the detector 46 and the body surface 12.
The displacement actuator 28 comprises a hydraulic cylinder 50 associated with each measurement sensor 26. The hydraulic cylinder 50 is fixed to a beam 38, 40, 42 of the support structure 24. It comprises a chamber 52, and a piston 54 that can be extended towards the body surface 12 from the chamber 52.
The measurement sensor 26 is connected to the piston 54 through the connection
48. The movement of the piston 54 can move the measurement sensor 26 from its retracted position to its extended position.
The adjustable connection elements 36 comprise a connection arm 53 articulated with the helmet 32. They also comprise lateral handles 55 that adjust the distance separating the perforated mask 34 from the body surface 12.
With reference to figure 6, the control unit 30 comprises a pneumatic control unit 56 to control each displacement actuator 28, a control unit 58, a memory 60 in which data received from measurements sensors 26 are stored, a wireless data transmission unit 62 designed to communicate with a remote programming unit and advantageously a battery 64.
The pneumatic unit 56 comprises a hydraulic fluid reservoir 66, and a plurality of pneumatic valves 68 hydraulically connected to the reservoir 66 to supply each displacement actuator 28.
The pneumatic unit 56 also comprises a pressure sensor 70 in the reservoir 66, a pump 72 to increase the pressure in the reservoir 66, and a leakage valve 74 designed to reduce the pressure in the reservoir 66. In this example, the reservoir 66 contains a hydraulic fluid composed of a liquid, for example an oil. As a variant, the hydraulic fluid may be a gas.
In this example, each pneumatic valve 68 is electrically connected for its control to the control unit 58.
Each displacement actuator 28 is connected to a first pneumatic valve 68 to control extension of the piston 54 and of the measurement sensor 26 towards the extended position and a second pneumatic valve 68 to control retraction of the piston 54 and the measurement sensor 26 towards its retracted position.
The pressure sensor 70 is designed to measure the pressure in the reservoir 66 and to transmit this information to the control unit 58. The pump 72 and the leakage valve 74 are each connected to the control unit 58 so that the control unit 58 can regulate the pressure in the reservoir 66 to a predetermined set value.
The control unit 58 can control each valve 68 to enable extension or retraction of a measurement sensor 26. It is capable of receiving a program to control activation of the measurement sensors 26 from a remote control unit, so that an analysis can be made using the predefined measurement protocol.
The control program comprises selection data for the regions 14 on the body surface 12 to be analyzed, selection data for the number of measurements to be made during the day, selection data for the time elapsed between two measurements, adjustable as a function of the time of the day, data of the amount of contact time between the measurement sensor 26 and the body surface 12, and possibly set contact pressure data to be applied by the measurement sensor 26 on the body surface 12.
These definition data are advantageously input in the remote programming unit and are transmitted using a wireless transmission protocol through the data transmission unit 62.
The wireless transmission protocol may for example be a Wifi type protocol (for example according to Standard IEEE 802.1 1 ), Bluetooth (for example according to IEEE standard 802.15-1 -2005).
Based on the definition data, the control unit 58 can create the selective activation protocol for each measurement sensor 26, and control each displacement actuator 28 as a function of the activation protocol.
The memory 60 is capable of collecting data measured by each measurement sensor 26 during its application on the body surface 12.
The wireless data transmission unit 62 is capable of transmitting measurement data to a remote recovery unit, ready for an analysis of data measured on each region 14 of the body surface 12. The analysis is made particularly as a function of time and as a function of the applied measurement protocol.
The battery 64 is able to provide an electrical power supply to components of the control unit 30.
The remote programming unit may for example be the same as the remote recovery unit. Each of these units may for example be formed by a portable apparatus, such as a smartphone, a tablet or a computer.
Advantageously, the global mass of the support structure 24 supporting the measurement sensors 26 is less than 1 kg. The control unit 30 advantageously fits into a container worn separately by the user.
The operation of a method for measuring at least one property of a body surface 12 of a user making use of the measurement tool 10 will now be described, in the framework of a protocol for measurements made for example on the user's face.
Initially, the support structure 24 is placed facing the body surface 12 to be analyzed. In this example, the user places the helmet 32 on his head, placing the perforated mask 34 in front of his face. He adjusts the distance locally separating the perforated mask 34 from the body surface 12 particularly by means of lateral handles 55.
The measurement sensors 26 are then put into their retracted position, at a distance from the body surface 12.
The user or a third person then activates the remote programing unit to define a measurement protocol to be followed. This measurement protocol is chosen by defining regions 24 to be analyzed on the body surface 12, and particularly measurement sensors 26 to be activated selectively, the number of measurements made by each measurement sensor 26 during the day, the time elapsed between two measurements, adjustable as a function of the time of day, the contact time between the measurement sensor 26 and the body surface 12, and possibly the application pressure of the measurements sensor 26 on the body surface 12.
This definition may for example be made using a specific application present in the remote programming unit. The application then creates definition data that are transmitted to the control unit 58 through the wireless data transmission unit 62, using a wireless transmission as defined above.
Thus, the control unit 30 is configured to define a predefined measurement protocol for each measurement sensor 26, comprising a number of displacements of the measurement sensor 26 between the retracted position and the extended position over time, at least one timeout during which the measurement sensor 26 is kept in the retracted position, at least one timeout during which the measurement sensor 26 is kept in the extended position, a target pressure applied by the measurement sensor 26 on the body surface 12 and/or a target temperature of the measurement sensor 26 on the body surface 12.
Having done this, the control unit 58 selectively activates the displacement actuators 28 as a function of the defined protocol to selectively apply one or several measurement sensors 26 onto the body surface 12.
To achieve this, in the example shown on figure 5, it activates a pneumatic valve 68 to extend the piston 54 outside the chamber 52 and move the selected measurement sensor 26 from its retracted position to its extended position, position in which the selected measurement sensor 26 is applied on the body surface 12.
During application, the connection 48 between the piston 54 and the sensor 26 assures gentle and precise contact of the measurement sensor 26 on the body surface 12, and appropriate placement of the detector 46 in contact with the body surface 12.
The contact made between the measurement sensor 26 and the body surface 12 is adjustable depending on the determined protocol, for example by applying a chosen and configurable pressure.
Advantageously, the measurement sensors 26 are gathered in a group so that they can be actuated alternately, which optimizes coverage of the face without creating a steric interaction.
Data collected by each measurement sensor 26 are stored in the memory 60, and are transmitted to the remote recovery unit through the wireless data transmission unit 62 using a wireless transmission protocol.
The data are then recorded in the recovery unit or in a "cloud" type computer architecture. Data are then processed by a processing application so that the measurement results can be displayed as a function of time and/or the region 14 of the body surface.
Advantageously, the analysis application enables an observation of macroscopic results on a face in three dimensions that may be the user's face or an average face reconstituted as a function of the user's ethnicity.
Therefore the measurement tool 10 according to the invention is particularly unobtrusive, since it leaves the body surface in its natural configuration throughout the user's day, with no occlusion. Therefore the body surface is subjected to natural variations applied to it as the environment changes over time.
However, the measurement tool 10 remains very precise because it can efficiently measure a large number of regions 14 on the body surface 12 either simultaneously or alternately, following a protocol that can very easily be defined and modified by an external programming unit.
It is thus possible to record a large amount of data, at key times during the user's day, to obtain a global and dynamic characterization of the body surface 12, in the laboratory, in a shop, or in the real life of a user.
Advantageously, the measurement method comprises a preliminary step to apply at least one cosmetic product, such as a make-up and care product, on the body surface 12. After the measurements have been made, the analysis step includes a determination of the impact of the cosmetic product on the measured properties, and therefore creates a quantification of the performance of the cosmetic product as a function of time when the body surface area 12 moves alive and transforms during the day.
This makes it possible to adapt the proposed cosmetic treatment to the user and to understand important criteria marking modifications to the body surface 12 during the day.
The evaluation made, based on several properties measured simultaneously, facilitates the understanding of mechanisms, and integrates experimental conditions into the analysis.
Individual control of sensors according to a predefined protocol can also optimize the measured skin surface.
If the sensor is relatively large, for example in the case of a chip described above, there may not be enough room for it in the extended position.
Defining sensor activation sequences can help to target very precise areas, and prevent any overlap of sensors when they are extended on the skin, while allowing the measurement zones to be adjacent to each other or even to overlap.
In one variant, the displacement actuator 28 is a piezoelectric actuator. Moreover, operation of the tool 10 is similar.
In another variant, represented diagrammatically on figure 7, the support structure 24 of the measurement tool 10 is composed of a film-shaped skin 80, facing and at a distance from the body surface 12.
The displacement actuator 28 is then formed by an inflatable pouch 82 that comprises a membrane 84 that can be extended from the skin 80. The membrane 84 carries the measurement sensor 26.
Inflation of the pouch 82 enables movement of the measurement sensor 26 from its retracted position to its extended position in contact with the body surface 12.
The skin 80 is advantageously translucent. It provides protection against external aggression (sun, wind, pollution, etc.) and visually conceals unesthetic variations (flush, heterogeneity, shine).

Claims

1 . - Tool (10) for measuring at least one property of a body surface (12) of a user, comprising:
- a support structure (24) intended to be placed facing the body surface (12) and at a distance from the body surface (12);
- at least one measurement sensor (26), supported by the support structure (24), intended to be applied on the body surface (12);
characterized in that the tool (10) comprises, for the or each measurement sensor (26):
- a displacement actuator (28) of the measurement sensor (26) causing displacement of the measurement sensor (26) between a retracted position in which the measurement sensor (26) is intended to be placed at a distance from the body surface (12) and an extended position in which the measurement sensor (26) is intended to come into contact with the body surface (12), the tool (10) comprising:
- a control unit (30) able to activate the displacement actuator (28) following a predefined measurement protocol, and in which in which the body surface (12) of the user is the user's face, the support structure (24) being able to be placed in front of the face.
2. - Tool (10) according to claim 1 in which the measurement sensor (26) is chosen from among a moisturization measurement sensor (26), a body surface relief measurement sensor (26) and/or a body surface shine measurement sensor (26), and/or a body surface microcirculation measurement sensor (26), and/or a sensor (26) for measuring the quantity of sebum on the skin surface, and/or a body surface color measurement sensor (26), and/or a body surface shine measurement sensor (26), and/or a sensor (26) for measuring the biomechanical properties of the body surface, and/or a body surface melanin content measurement sensor (26), and/or a body surface hydric mobility measurement sensor (26), and/or a sensor (26) for measuring the density and size of body surface cells.
3. - Tool (10) according to claim 1 or 2, comprising several measurement sensors (26) supported by the support structure (24), particularly more than ten measurement sensors (26) supported by the support structure (24).
4. - Tool (10) according to any one of the previous claims, in which at least one measurement sensor (26) is intended to be placed facing the user's chin (20), at least one measurement sensor (26) being intended to be placed facing the user's cheeks (18), at least one measurement sensor (26) being intended to be placed facing the user's forehead (16).
5. - Tool (10) according to any one of the previous claims, in which the support structure (24) comprises a perforated frame (34), the or each measurement sensor (26) being extendable by means of the displacement actuator (28) from the perforated frame (34).
6. - Tool (10) according to claim 5, in which the displacement actuator (28) comprises a hydraulic cylinder (50), or a piezoelectric displacement mechanism connecting the perforated frame (34) to the or to each measurement sensor (26).
7.- Tool (10) according to any one of claims 1 to 4, in which the support structure (24) is composed of a skin (80).
8. - Tool (10) according to claim 7, in which the displacement actuator (28) comprises a membrane (84) able to extend from the skin (80), the extendable membrane (84) supporting the measurement sensor (26).
9. - Tool (10) according to any one of the previous claims, in which the or each measurement sensor (26) is connected to the displacement actuator (28) by a connection (48) comprising at least one degree of freedom in rotation.
10. - Tool (10) according to any one of the previous claims, in which the control unit (30) is able to be configured to define a predefined measurement protocol for each measurement sensor (26), the predefined measurement protocol comprising a number of displacements of the measurement sensor (26) between the retracted position and the extended position over time, at least one timeout during which the measurement sensor (26) is kept in the retracted position, at least one timeout during which the measurement sensor (26) is kept in the extended position, a target pressure applied by the measurement sensor (26) on the body surface (12) and/or a target temperature of the measurement sensor (26) on the body surface (12).
1 1 .- Tool (10) according to any one of the previous claims, comprising a unit (62) for wireless transmission of data acquired by the or each measurement sensor (26) to a remote recovery unit and/or for transmitting measurement protocol definition data from a remote programming unit.
12.- Method for measuring at least one property of a body surface (12) of a user, comprising the following steps:
- arrangement of a tool (10) according to any of the previous claims facing the body surface (12), the or each measurement sensor (26) being positioned in its retracted position at a distance from the body surface (12);
- activation of the displacement actuator (28) by the control unit (30) to move the measurement sensor (26) from its retracted position to its extended position in contact with the body surface (12); - measurement of at least one property of the body surface (12) by the measurement sensor (26);
- control of the displacement actuator (28) by the control unit (30) to move the measurement sensor (26) from its extended position to its retracted position.
EP18769184.5A 2017-09-13 2018-09-13 Tool for measuring at least one property of a body surface and associated measurement method Withdrawn EP3681377A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1758488A FR3070845B1 (en) 2017-09-13 2017-09-13 TOOL FOR MEASURING AT LEAST ONE PROPERTY OF A BODY SURFACE AND ASSOCIATED MEASUREMENT METHOD
PCT/EP2018/074824 WO2019053168A1 (en) 2017-09-13 2018-09-13 Tool for measuring at least one property of a body surface and associated measurement method

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DE102018107224A1 (en) 2018-02-21 2019-08-22 Immatics Biotechnologies Gmbh Peptides and combinations of peptides of non-canonical origin for use in immunotherapy against various cancers
IL306145A (en) * 2020-03-13 2024-10-01 Ichilov Tech Ltd Eeg electrode array and method of use

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FR2812532B1 (en) 2000-08-01 2003-07-04 Oreal METHOD FOR ACQUIRING AN IMAGE OF A NON-DERMATHOGLYPHIC ZONE OF THE SKIN OR A HAIR ZONE BY MEANS OF AN ACQUISITION DEVICE INCLUDING A NON-OPTICAL SENSOR
FR2849764B1 (en) 2003-01-14 2012-12-14 Oreal DEVICE AND METHOD, IN PARTICULAR FOR EVALUATING THE MOISTURIZATION OF THE SKIN OR MUCOSES
IL283615B2 (en) * 2011-12-20 2025-08-01 Sensible Medical Innovations Ltd Chest garment for placement of electromagnetic transducers and methods for using chest garment
US20170164878A1 (en) * 2012-06-14 2017-06-15 Medibotics Llc Wearable Technology for Non-Invasive Glucose Monitoring
KR20150115452A (en) * 2014-04-04 2015-10-14 삼성전자주식회사 Wearable type electronic device
KR101654413B1 (en) * 2014-05-21 2016-09-05 최충식 Smart mask for healthcare service
WO2016019002A1 (en) * 2014-07-30 2016-02-04 Valencell, Inc. Physiological monitoring devices with adjustable stability
US20180352937A1 (en) 2015-09-04 2018-12-13 Wb Technologies System for analysis and activation and/or localised release for the human face

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