EP3562475A4 - Thin film formulations of 4-diphenylmethyl-1-piperazine derivatives and their salts - Google Patents

Thin film formulations of 4-diphenylmethyl-1-piperazine derivatives and their salts Download PDF

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Publication number
EP3562475A4
EP3562475A4 EP17889328.5A EP17889328A EP3562475A4 EP 3562475 A4 EP3562475 A4 EP 3562475A4 EP 17889328 A EP17889328 A EP 17889328A EP 3562475 A4 EP3562475 A4 EP 3562475A4
Authority
EP
European Patent Office
Prior art keywords
diphenylmethyl
salts
thin film
piperazine derivatives
film formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17889328.5A
Other languages
German (de)
French (fr)
Other versions
EP3562475A1 (en
Inventor
Anwar Siraj DAUD
Nidhi Prakash SAPKAL
Minal Nandkumar BONDE
Shikha BARVE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zim Laboratories Ltd
Original Assignee
Zim Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zim Laboratories Ltd filed Critical Zim Laboratories Ltd
Publication of EP3562475A1 publication Critical patent/EP3562475A1/en
Publication of EP3562475A4 publication Critical patent/EP3562475A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP17889328.5A 2016-12-27 2017-12-22 Thin film formulations of 4-diphenylmethyl-1-piperazine derivatives and their salts Pending EP3562475A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201621044488 2016-12-27
PCT/IN2017/050613 WO2018122867A1 (en) 2016-12-27 2017-12-22 Thin film formulations of 4-diphenylmethyl-1-piperazine derivatives and their salts

Publications (2)

Publication Number Publication Date
EP3562475A1 EP3562475A1 (en) 2019-11-06
EP3562475A4 true EP3562475A4 (en) 2020-07-01

Family

ID=62707074

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17889328.5A Pending EP3562475A4 (en) 2016-12-27 2017-12-22 Thin film formulations of 4-diphenylmethyl-1-piperazine derivatives and their salts

Country Status (2)

Country Link
EP (1) EP3562475A4 (en)
WO (1) WO2018122867A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108840417A (en) * 2018-07-06 2018-11-20 佛山市陵谐环保科技有限公司 A kind of preparation method of food and drink waste water flocculant
CN110726788B (en) * 2019-11-15 2022-07-01 湖南九典制药股份有限公司 Method for separating and measuring levocetirizine hydrochloride and related substances thereof by high performance liquid chromatography
CN111821290A (en) * 2020-02-27 2020-10-27 鲁南制药集团股份有限公司 Method for detecting cetirizine hydrochloride related substances
CN114788809B (en) * 2022-01-25 2023-04-14 江苏广承药业有限公司 Loratadine liquid preparation
CN114923965B (en) * 2022-03-18 2023-05-23 杭州微策生物技术股份有限公司 Integrated multi-index sensor and manufacturing method thereof
CN117243927A (en) * 2023-10-17 2023-12-19 深圳市泰力生物医药有限公司 Caliperazine hydrochloride oral soluble film preparation containing safe and effective taste masking agent and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006061700A2 (en) * 2004-12-06 2006-06-15 Themis Laboratories Private Limited Rapid disintegrating taste masked compositions and a process for its preparations
US20100112050A1 (en) * 2008-11-03 2010-05-06 Je Phil Ryoo Dosage Form For Insertion Into The Mouth
DE102010049708A1 (en) * 2010-10-28 2012-05-03 Hexal Ag Oral pharmaceutical film formulation for bitter-tasting drugs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008119033A1 (en) * 2007-03-27 2008-10-02 Eurand, Inc. Pharmaceutical compositions comprising an active substance from the substituted benzhydrylpiperazine family
KR101407922B1 (en) * 2013-11-14 2014-06-17 주식회사 서울제약 Porous Orally Disintegrating Film comprising pharmacologically active substance and Precess For Producing thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006061700A2 (en) * 2004-12-06 2006-06-15 Themis Laboratories Private Limited Rapid disintegrating taste masked compositions and a process for its preparations
US20100112050A1 (en) * 2008-11-03 2010-05-06 Je Phil Ryoo Dosage Form For Insertion Into The Mouth
DE102010049708A1 (en) * 2010-10-28 2012-05-03 Hexal Ag Oral pharmaceutical film formulation for bitter-tasting drugs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2018122867A1 *

Also Published As

Publication number Publication date
WO2018122867A1 (en) 2018-07-05
EP3562475A1 (en) 2019-11-06

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