EP3285742A4 - Plättchenförmige proteo-mikropartikel und verfahren zur verwendung davon in der arzneimittelverabreichung - Google Patents
Plättchenförmige proteo-mikropartikel und verfahren zur verwendung davon in der arzneimittelverabreichung Download PDFInfo
- Publication number
- EP3285742A4 EP3285742A4 EP16782388.9A EP16782388A EP3285742A4 EP 3285742 A4 EP3285742 A4 EP 3285742A4 EP 16782388 A EP16782388 A EP 16782388A EP 3285742 A4 EP3285742 A4 EP 3285742A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- proteo
- microparticles
- platelet
- drug delivery
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562149849P | 2015-04-20 | 2015-04-20 | |
PCT/AU2016/000135 WO2016168884A1 (en) | 2015-04-20 | 2016-04-20 | Platelet-like proteo-microparticles and method of using such in drug delivery |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3285742A1 EP3285742A1 (de) | 2018-02-28 |
EP3285742A4 true EP3285742A4 (de) | 2018-11-21 |
Family
ID=57142766
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16782388.9A Pending EP3285742A4 (de) | 2015-04-20 | 2016-04-20 | Plättchenförmige proteo-mikropartikel und verfahren zur verwendung davon in der arzneimittelverabreichung |
Country Status (6)
Country | Link |
---|---|
US (1) | US10835493B2 (de) |
EP (1) | EP3285742A4 (de) |
JP (1) | JP6874995B2 (de) |
CN (1) | CN107847442B (de) |
TW (1) | TWI651092B (de) |
WO (1) | WO2016168884A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109157513B (zh) * | 2018-07-27 | 2020-11-06 | 湖北大学 | 一种血栓靶向长循环缓释脂质体及其制备方法 |
EP3739321B1 (de) * | 2019-05-17 | 2023-03-08 | Xtal Concepts GmbH | Qualifizierungsverfahren für kryoelektronenmikroskopie-proben sowie dazugehöriger probenhalter |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5238919A (en) * | 1986-05-30 | 1993-08-24 | Scipps Clinic And Research Foundation | Peptides that inhibit von Willebrand Factor binding to the platelet SPIB receptor |
US5503982A (en) * | 1993-09-30 | 1996-04-02 | Research Corporation Technologies, Inc. | Detection of an acute myocardial infarction in a patient |
JP3735921B2 (ja) * | 1996-02-07 | 2006-01-18 | 三菱ウェルファーマ株式会社 | GPIb・脂質複合体およびその用途 |
CN1318035C (zh) | 2003-09-18 | 2007-05-30 | 中国人民解放军军事医学科学院野战输血研究所 | 一种人血小板代用品及其制备方法 |
JP5216219B2 (ja) * | 2006-01-06 | 2013-06-19 | 真司 武岡 | 薬物運搬体 |
WO2007077990A1 (ja) * | 2006-01-06 | 2007-07-12 | Keio University | 薬物運搬体 |
EP2018436A2 (de) * | 2006-04-25 | 2009-01-28 | Immune Disease Institute Inc. | Gezielte abgabe an leukozyten mit nicht-proteinträgern |
US8512697B2 (en) * | 2007-05-16 | 2013-08-20 | The University Of North Carolina At Chapel Hill | Delivery of micro- and nanoparticles with blood platelets |
US20100151573A1 (en) * | 2008-11-17 | 2010-06-17 | King Michael R | Compositions and methods for delivery of molecules to selectin-ligand-expressing and selectin-expressing cells |
US9107845B2 (en) * | 2011-04-13 | 2015-08-18 | Case Western Reserve University | Synthetic platelets |
CA2873404C (en) * | 2011-06-02 | 2022-08-30 | The Regents Of The University Of California | Membrane encapsulated nanoparticles and method of use |
US9107963B2 (en) | 2012-04-13 | 2015-08-18 | Case Western Reserve University | Heteromultivalent nanoparticle compositions |
US20140186431A1 (en) * | 2013-01-03 | 2014-07-03 | Temple University - Of The Commonwealth System Of Higher Education | Combined mesenchymal stem cell transplantation and targeted delivery of vegf for treatment of myocardial infarction |
-
2016
- 2016-04-20 EP EP16782388.9A patent/EP3285742A4/de active Pending
- 2016-04-20 CN CN201680023313.6A patent/CN107847442B/zh active Active
- 2016-04-20 US US15/567,837 patent/US10835493B2/en active Active
- 2016-04-20 TW TW105112236A patent/TWI651092B/zh active
- 2016-04-20 JP JP2017554600A patent/JP6874995B2/ja active Active
- 2016-04-20 WO PCT/AU2016/000135 patent/WO2016168884A1/en active Application Filing
Non-Patent Citations (3)
Title |
---|
CHARLES J HAMORI ET AL: "Targeting Zinc Protoporphyrin Liposomes to the Spleen Using Reticuloendothelial Blockade with Blank Liposomes", PEDIATRIC RESEARCH, vol. 34, no. 1, 1 July 1993 (1993-07-01), US, pages 1 - 5, XP055503925, ISSN: 0031-3998, DOI: 10.1203/00006450-199307000-00001 * |
EUGENE JANG, HASSAN ALBADAWI, MICHAEL T. WATKINS, ELAZER R. EDELMAN, AARON B. BAKER: "Syndecan-4 proteoliposomes enhance fibroblast growth factor-2 (FGF-2)-induced proliferation, migration, and neovascularization of ischemic muscle", PNAS, vol. 109, no. 5, 31 January 2012 (2012-01-31), XP002785710 * |
See also references of WO2016168884A1 * |
Also Published As
Publication number | Publication date |
---|---|
JP2018513170A (ja) | 2018-05-24 |
EP3285742A1 (de) | 2018-02-28 |
US10835493B2 (en) | 2020-11-17 |
CN107847442A (zh) | 2018-03-27 |
US20180092846A1 (en) | 2018-04-05 |
TW201641118A (zh) | 2016-12-01 |
JP6874995B2 (ja) | 2021-05-19 |
CN107847442B (zh) | 2021-03-16 |
WO2016168884A1 (en) | 2016-10-27 |
TWI651092B (zh) | 2019-02-21 |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20181024 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 9/10 20060101ALI20181017BHEP Ipc: A61K 31/409 20060101ALI20181017BHEP Ipc: A61K 9/127 20060101AFI20181017BHEP Ipc: A61K 31/24 20060101ALI20181017BHEP Ipc: A61K 9/14 20060101ALI20181017BHEP |
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17Q | First examination report despatched |
Effective date: 20210907 |