EP3283087A4 - Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions - Google Patents

Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions Download PDF

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Publication number
EP3283087A4
EP3283087A4 EP16780681.9A EP16780681A EP3283087A4 EP 3283087 A4 EP3283087 A4 EP 3283087A4 EP 16780681 A EP16780681 A EP 16780681A EP 3283087 A4 EP3283087 A4 EP 3283087A4
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EP
European Patent Office
Prior art keywords
microbiome
therapeutics
derived diagnostics
conditions
endocrine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16780681.9A
Other languages
German (de)
French (fr)
Other versions
EP3283087A1 (en
Inventor
Zachary APTE
Daniel Almonacid
Jessica RICHMAN
Siavosh Rezvan BEHBAHANI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Psomagen Inc
Original Assignee
uBiome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by uBiome Inc filed Critical uBiome Inc
Publication of EP3283087A1 publication Critical patent/EP3283087A1/en
Publication of EP3283087A4 publication Critical patent/EP3283087A4/en
Pending legal-status Critical Current

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Data Mining & Analysis (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Databases & Information Systems (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Software Systems (AREA)
  • Genetics & Genomics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Analytical Chemistry (AREA)
  • Primary Health Care (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Evolutionary Computation (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
EP16780681.9A 2015-04-14 2016-04-13 Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions Pending EP3283087A4 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201562147355P 2015-04-14 2015-04-14
US201562147348P 2015-04-14 2015-04-14
US201562147107P 2015-04-14 2015-04-14
US201562147058P 2015-04-14 2015-04-14
US201562147304P 2015-04-14 2015-04-14
US201562147202P 2015-04-14 2015-04-14
US201562147226P 2015-04-14 2015-04-14
PCT/US2016/027378 WO2016168370A1 (en) 2015-04-14 2016-04-13 Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions

Publications (2)

Publication Number Publication Date
EP3283087A1 EP3283087A1 (en) 2018-02-21
EP3283087A4 true EP3283087A4 (en) 2019-03-13

Family

ID=57126198

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16780681.9A Pending EP3283087A4 (en) 2015-04-14 2016-04-13 Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions

Country Status (4)

Country Link
EP (1) EP3283087A4 (en)
CN (1) CN107708714B (en)
AU (2) AU2016250159A1 (en)
WO (1) WO2016168370A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3006057A1 (en) * 2015-09-09 2017-03-16 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with thyroid health issues
CN111373481A (en) * 2018-03-16 2020-07-03 普梭梅根公司 Methods and systems for characterizing metabolic-related disorders based on bioinformatics methods, including diagnosis and therapy
CN114381507B (en) * 2021-11-25 2024-02-13 杭州拓宏生物科技有限公司 Graves disease marker microorganism and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130121968A1 (en) * 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
WO2015013214A2 (en) * 2013-07-21 2015-01-29 Whole Biome, Inc. Methods and systems for microbiome characterization, monitoring and treatment

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120149584A1 (en) * 2009-08-21 2012-06-14 Bernat Olle Methods of diagnosing and treating microbiome-associated disease using interaction network parameters
CN102939391A (en) * 2010-03-01 2013-02-20 国家农艺研究院 Method of diagnostic of inflammatory bowel diseases
CN102939392A (en) * 2010-03-01 2013-02-20 国家农艺研究院 Method of diagnostic of obesity
WO2013067146A1 (en) * 2011-11-04 2013-05-10 General Mills, Inc. Methods and compositions for modulating gastrointestinal bacteria to promote health
KR20230110367A (en) * 2013-02-04 2023-07-21 세레스 테라퓨틱스, 인코포레이티드 Compositions and methods
WO2014190229A1 (en) * 2013-05-24 2014-11-27 President And Fellows Of Harvard College Methods of isolating microorganisms and uses thereof
US20150050245A1 (en) * 2013-08-14 2015-02-19 Tntgamble, Inc. Methods and delivery system for beneficial additive and subtractive biological agents to promote balanced mammalian gastrointestinal flora
WO2016065075A1 (en) * 2014-10-21 2016-04-28 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics
EP3881680A1 (en) * 2014-10-31 2021-09-22 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment
WO2016168364A1 (en) * 2015-04-13 2016-10-20 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions
EP3283086A4 (en) * 2015-04-13 2019-04-24 Ubiome Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features
EP3283085A4 (en) * 2015-04-13 2019-04-10 Ubiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome taxonomic features
CN107710205A (en) * 2015-04-14 2018-02-16 优比欧迈公司 For the sign in the microorganism group source of cardiovascular disease condition, diagnosis and the method and system for the treatment of

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130121968A1 (en) * 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
WO2015013214A2 (en) * 2013-07-21 2015-01-29 Whole Biome, Inc. Methods and systems for microbiome characterization, monitoring and treatment

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VIRILI CAMILLA ET AL: "Does microbiota composition affect thyroid homeostasis?", ENDOCRINE, HUMANA PRESS, INC, US, vol. 49, no. 3, 17 December 2014 (2014-12-17), pages 583 - 587, XP035520794, ISSN: 1355-008X, [retrieved on 20141217], DOI: 10.1007/S12020-014-0509-2 *

Also Published As

Publication number Publication date
WO2016168370A1 (en) 2016-10-20
CN107708714B (en) 2022-07-22
AU2016250159A1 (en) 2017-11-09
EP3283087A1 (en) 2018-02-21
CN107708714A (en) 2018-02-16
AU2022200575A1 (en) 2022-02-17

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