EP3283086A4 - Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features - Google Patents

Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features Download PDF

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Publication number
EP3283086A4
EP3283086A4 EP16780670.2A EP16780670A EP3283086A4 EP 3283086 A4 EP3283086 A4 EP 3283086A4 EP 16780670 A EP16780670 A EP 16780670A EP 3283086 A4 EP3283086 A4 EP 3283086A4
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EP
European Patent Office
Prior art keywords
microbiome
therapeutics
conditions associated
functional features
derived diagnostics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP16780670.2A
Other languages
German (de)
French (fr)
Other versions
EP3283086A1 (en
Inventor
Zachary APTE
Daniel Almonacid
Jessica RICHMAN
Siavosh Rezvan BEHBAHANI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Psomagen Inc
Original Assignee
uBiome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by uBiome Inc filed Critical uBiome Inc
Publication of EP3283086A1 publication Critical patent/EP3283086A1/en
Publication of EP3283086A4 publication Critical patent/EP3283086A4/en
Withdrawn legal-status Critical Current

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Data Mining & Analysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Software Systems (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Primary Health Care (AREA)
  • Evolutionary Computation (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP16780670.2A 2015-04-13 2016-04-13 Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features Withdrawn EP3283086A4 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562146833P 2015-04-13 2015-04-13
US201562147334P 2015-04-14 2015-04-14
US201562147202P 2015-04-14 2015-04-14
US201562147058P 2015-04-14 2015-04-14
US201562147077P 2015-04-14 2015-04-14
PCT/US2016/027359 WO2016168354A1 (en) 2015-04-13 2016-04-13 Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features

Publications (2)

Publication Number Publication Date
EP3283086A1 EP3283086A1 (en) 2018-02-21
EP3283086A4 true EP3283086A4 (en) 2019-04-24

Family

ID=57126305

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16780670.2A Withdrawn EP3283086A4 (en) 2015-04-13 2016-04-13 Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features

Country Status (4)

Country Link
EP (1) EP3283086A4 (en)
CN (1) CN107708715B (en)
AU (1) AU2016250104B2 (en)
WO (1) WO2016168354A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016250159A1 (en) * 2015-04-14 2017-11-09 Psomagen, Inc. Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions
AU2016321348A1 (en) * 2015-09-09 2018-04-26 Psomagen, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with thyroid health issues
EP3687375A4 (en) * 2016-11-21 2022-01-19 Psomagen, Inc. Method and system for characterizing a headache-related condition
WO2018112437A1 (en) * 2016-12-15 2018-06-21 uBiome, Inc. Method and system for characterizing allergy-related conditions associated with microorganisms
WO2018112419A1 (en) * 2016-12-15 2018-06-21 uBiome, Inc. Method and system for characterizing diet-related conditions
WO2018112459A1 (en) * 2016-12-16 2018-06-21 uBiome, Inc. Method and system for characterizing microorganism-related conditions
SG11202002500SA (en) * 2017-11-06 2020-04-29 Psomagen Inc Control processes for microorganism-related characterization processes
CN113348367A (en) * 2018-10-31 2021-09-03 卡尤迪医学检验实验室（北京）有限公司 Methods, systems and kits for predicting preterm labor status
WO2020131923A1 (en) * 2018-12-17 2020-06-25 uBiome, Inc. Automatic standardization pipeline for data analysis
WO2022269598A1 (en) * 2021-06-20 2022-12-29 Biotax Labs Ltd. System and method for predicting a medical condition based on a biological sample
CN114452305B (en) * 2022-03-17 2024-07-26 北京航空航天大学 Application of bacteroides simplex in preparing medicament for preventing and treating anxiety depression
CN117409978B (en) * 2023-12-15 2024-04-19 贵州大学 Disease prediction model construction method, system, device and readable storage medium
CN117771278A (en) * 2024-02-26 2024-03-29 四川大学华西医院 Application of Prevotella copri in preparation of medicine for treating senile debilitation syndrome

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130121968A1 (en) * 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
US20140065132A1 (en) * 2012-08-29 2014-03-06 California Institute Of Technology Diagnosis and treatment of autism spectrum disorder
WO2014053608A1 (en) * 2012-10-03 2014-04-10 Metabogen Ab Identification of a person having risk for atherosclerosis and associated diseases by the person's gut microbiome and the prevention of such diseases
WO2015027116A1 (en) * 2013-08-21 2015-02-26 The Regents Of The University Of California Diagnostic and predictive metabolite patterns for disorders affecting the brain and nervous system

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011022660A1 (en) * 2009-08-21 2011-02-24 Puretech Ventures, Llc Methods of diagnosing and treating microbiome-associated disease using interaction network parameters
BR112013022927A2 (en) * 2011-03-09 2016-12-06 Univ Minnesota composition, methods for replacing or supplementing or modifying a subject's microbiota of the colon, and for treating a subject, and, use of a composition
BR112015018625A2 (en) * 2013-02-04 2017-09-19 Seres Therapeutics Inc compositions and methods
CN105407728A (en) * 2013-07-21 2016-03-16 霍勒拜欧姆公司 Methods and systems for microbiome characterization, monitoring and treatment
US10329628B2 (en) * 2014-01-25 2019-06-25 uBiome, Inc. Method and system for microbiome analysis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130121968A1 (en) * 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
US20140065132A1 (en) * 2012-08-29 2014-03-06 California Institute Of Technology Diagnosis and treatment of autism spectrum disorder
WO2014053608A1 (en) * 2012-10-03 2014-04-10 Metabogen Ab Identification of a person having risk for atherosclerosis and associated diseases by the person's gut microbiome and the prevention of such diseases
WO2015027116A1 (en) * 2013-08-21 2015-02-26 The Regents Of The University Of California Diagnostic and predictive metabolite patterns for disorders affecting the brain and nervous system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2016168354A1 *

Also Published As

Publication number Publication date
CN107708715B (en) 2022-06-03
EP3283086A1 (en) 2018-02-21
WO2016168354A1 (en) 2016-10-20
CN107708715A (en) 2018-02-16
AU2016250104B2 (en) 2022-02-10
AU2016250104A1 (en) 2017-11-09

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