EP3203859A1 - Use of canthaxanthin for laying hens - Google Patents

Use of canthaxanthin for laying hens

Info

Publication number
EP3203859A1
EP3203859A1 EP15771638.2A EP15771638A EP3203859A1 EP 3203859 A1 EP3203859 A1 EP 3203859A1 EP 15771638 A EP15771638 A EP 15771638A EP 3203859 A1 EP3203859 A1 EP 3203859A1
Authority
EP
European Patent Office
Prior art keywords
canthaxanthin
egg
ppm
vitamin
per ppm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15771638.2A
Other languages
German (de)
French (fr)
Inventor
Murtala UMAR FARUK
Franz Roos
Fernando CISNEROS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of EP3203859A1 publication Critical patent/EP3203859A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/179—Colouring agents, e.g. pigmenting or dyeing agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Definitions

  • the present invention is in the general field of poultry farming. More particularly, the invention relates to a method of feeding female birds with a feed formulation which enhances egg mass.
  • Poultry diets of this invention are typically diets which include canthaxanthin in an amount such that the average egg mass is increased compared to animals treated without canthaxanthin.
  • This invention also relates to improved poultry farming.
  • it relates to methods which provide improved egg production. These methods comprise obtaining an increase in yield of marketable eggs from laying hens. The increase is provided by feeding hens a diet of this invention.
  • the demand for poultry eggs, especially chicken eggs expanded considerably over the last decade.
  • the poultry industry has grown from a home industry to a large scale manufacturing industry in which tens of thousands of eggs are produced daily at single farms or egg laying installations. Some eggs are produced for eating and some eggs are produced for hatching.
  • One problem with such large scale egg producing is keeping the percent of salable eggs for food consumption on a high level during the increased pressure on farming conditions.
  • the egg quality in particular the egg mass
  • canthaxanthin in poultry diets has been to enhance yolk or meet colour as this greatly influences consumer purchasing behaviour.
  • other functionalities such as antioxidant effect, enhanced reproduction and immune-modulation are attributed to canthaxanthin.
  • egg production can be incrementally increased by supplementing the diet with canthaxanthin is a completely unanticipated result in laying hen egg production. This supplementation is economical and easy to administer.
  • Pesttry is meant to include turkeys, ducks and chickens (limited to layers).
  • Canthaxanthin may be obtained from any source, and a composition thereof may be prepared using convenient technology.
  • the invention is related to the use of canthaxanthin as nutrients to increase egg mass.
  • a feed for laying hens which comprises from about 1 to 50 ppm canthaxanthin, preferably 2 to 10 ppm to increase egg mass.
  • the method for improving egg mass in poultry comprises administering to the animal in need of such treatment an amount of about 1 ppm to 50 ppm of canthaxanthin, preferably 2 to 10 ppm, for example, 2; 2,5; 3; 3,5; 4; 4,5; 5; 5,5; 6; 6.5; 7; 7,5; 8 ppm.
  • the diet of poultry is advantageously supplemented with canthaxanthin in physiologically effective amounts.
  • the canthaxanthin used in the examples reported below is is available under the Trademark CAROPHYLL ® Red.
  • Canthaxanthin is suitably administered together with the feed.
  • feed as used herein comprises both solid and liquid feed as well as drinking fluids such as drinking water.
  • inventive ingredient can be added as a formulated powder to a premix containing minerals, vitamins, amino acids and trace elements which is added to regular animal feed and thorough mixing to achieve even distribution therein.
  • a premix containing minerals, vitamins, amino acids and trace elements which is added to regular animal feed and thorough mixing to achieve even distribution therein.
  • a food premix may be prepared on the basis of regular food components by adding this active ingredient to such feed components in higher concentration.
  • the composition also contains one or more of the following ingredients: Vitamin A, Vitamin E, Biotin, copper (e.g. as CuS0 4 ), zinc (e.g.
  • ZnS0 4 cobalt (e.g. as CoS0 4 ), selenium (e.g. as Na 2 Se0 3 ), iodine (e.g. as Kl), manganese (e.g. as MnS0 4 ) and/or calcium (e.g. as CaS0 4 ).
  • cobalt e.g. as CoS0 4
  • selenium e.g. as Na 2 Se0 3
  • iodine e.g. as Kl
  • manganese e.g. as MnS0 4
  • CaS0 4 calcium
  • Example 1 Effect of Canthaxanthin on the productivity of layer hens (1 st trial)
  • the diet given to the birds was a standard feed for layer hens (Mash fed ad libitum) with the addition of the product that was tested.
  • the feed met all nutritional requirements in relation to the developmental stage of the birds and the recommendations in the layers' guide (Table 1 ).
  • Vitamin and mineral premix supplies the following per kilogram of diet: vitamin A, 1000000 IU; vitamin D3, 300000 IU; vitamin E 3000 IU; vitamin K3 250 mg; vitamin B1 200 mg; vitamin B2 600 mg; vitamin B5 900 mg; vitamin B6 400 mg; folic acid 80mg; vitamin B12 2000 mg; niacin 3000 mg; biotin 13 mg; vitamin C 10000 mg; choline 25950 mg; iron 5000 mg; cupper 1000 mg; zinc 7000 mg; manganese 12000 mg; iodine 124 mg; cobalt 100 mg; selenium 19,8 mg,
  • the diet given to the birds was a standard feed for layer hens (Mash fed ad libitum) with the addition of the product that was tested.
  • the feed met all nutritional requirements in relation to the developmental stage of the birds and the recommendations in the layers' guide (Table 1 ). TABLE 1 . Composition of feed used during the experiment
  • Vitamin and mineral premix supplies the following per kilogram of diet: vitamin A, 1000000 IU; vitamin D3, 300000 IU; vitamin E 3000 IU; vitamin K3 250 mg; vitamin B1 200 mg; vitamin B2 600 mg; vitamin B5 900 mg; vitamin B6 400 mg; folic acid 80mg; vitamin B12 2000 mg; niacin 3000 mg; biotin 13 mg; vitamin C 10000 mg; choline 25950 mg; iron 5000 mg; cupper 1000 mg; zinc 7000 mg; manganese 12000 mg; iodine 124 mg; cobalt 100 mg; selenium 19,8 mg,

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Birds (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The present invention relates to the use of canthaxanthin for improving egg production. More particularly, the invention relates to the use of canthaxanthin for increasing egg mass. It has been observed surprisingly that the dietary canthaxanthin supplementation of layer hen diet improved production parameters. Canthaxanthin (per unit of dietary inclusion) increased layer hen feed intake by 0.32% per ppm, FCR by -0.24% per ppm, egg production by 0.28% per ppm, and egg weight by 0.17% per ppm compared to control diet without canthaxanthin. Egg mass was significantly improved by 0.47% per ppm. These results revealed that canthaxanthin can enhance the productivity of egg farms in addition to yolk coloration, antioxidant effect, enhanced reproduction and immune-modulation.

Description

USE OF CANTHAXANTHIN FOR LAYING HENS
FIELD OF THE INVENTION
The present invention is in the general field of poultry farming. More particularly, the invention relates to a method of feeding female birds with a feed formulation which enhances egg mass.
Poultry diets of this invention are typically diets which include canthaxanthin in an amount such that the average egg mass is increased compared to animals treated without canthaxanthin.
This invention also relates to improved poultry farming. Thus, it relates to methods which provide improved egg production. These methods comprise obtaining an increase in yield of marketable eggs from laying hens. The increase is provided by feeding hens a diet of this invention.
BACKGROUND
The demand for poultry eggs, especially chicken eggs expanded considerably over the last decade. The poultry industry has grown from a home industry to a large scale manufacturing industry in which tens of thousands of eggs are produced daily at single farms or egg laying installations. Some eggs are produced for eating and some eggs are produced for hatching. One problem with such large scale egg producing is keeping the percent of salable eggs for food consumption on a high level during the increased pressure on farming conditions.
Therefore, the desirability of an easy-to-implement means of increasing egg production in poultry requires no citation.
It has now been found, quite unexpectedly, that the egg quality, in particular the egg mass, can be increased by administering to the animals an effective amount of canthaxanthin.
The major use of canthaxanthin in poultry diets has been to enhance yolk or meet colour as this greatly influences consumer purchasing behaviour. In addition, other functionalities such as antioxidant effect, enhanced reproduction and immune-modulation are attributed to canthaxanthin. The fact, that egg production can be incrementally increased by supplementing the diet with canthaxanthin is a completely unanticipated result in laying hen egg production. This supplementation is economical and easy to administer. We presently have no explanation for the mechanism underlying this increase in egg production. These results revealed that canthaxanthin can enhance the productivity of egg farms in addition to yolk coloration, antioxidant effect, enhanced reproduction and immune-modulation.
No prior reference suggests that the administration of canthaxanthin would be expected to have any effect on egg mass in poultry. DETAILED DESCRIPTION OF THE INVENTION
As used throughout the specification and claims, the following definitions apply:
"Poultry" is meant to include turkeys, ducks and chickens (limited to layers).
Canthaxanthin may be obtained from any source, and a composition thereof may be prepared using convenient technology. In a first aspect, the invention is related to the use of canthaxanthin as nutrients to increase egg mass.
In a second aspect, a feed for laying hens is provided which comprises from about 1 to 50 ppm canthaxanthin, preferably 2 to 10 ppm to increase egg mass.
The method for improving egg mass in poultry comprises administering to the animal in need of such treatment an amount of about 1 ppm to 50 ppm of canthaxanthin, preferably 2 to 10 ppm, for example, 2; 2,5; 3; 3,5; 4; 4,5; 5; 5,5; 6; 6.5; 7; 7,5; 8 ppm.
The diet of poultry is advantageously supplemented with canthaxanthin in physiologically effective amounts. The canthaxanthin used in the examples reported below is is available under the Trademark CAROPHYLL®Red. Canthaxanthin is suitably administered together with the feed. The term feed as used herein comprises both solid and liquid feed as well as drinking fluids such as drinking water.
Particularly, inventive ingredient can be added as a formulated powder to a premix containing minerals, vitamins, amino acids and trace elements which is added to regular animal feed and thorough mixing to achieve even distribution therein. In the manufacture of poultry feed in accordance with the invention, from about 1 ppm to 50 ppm, preferably 2 - 10 ppm of canthaxanthin is added to regular poultry food. Alternatively, a food premix may be prepared on the basis of regular food components by adding this active ingredient to such feed components in higher concentration. According to the present invention it is further advantageous if the composition also contains one or more of the following ingredients: Vitamin A, Vitamin E, Biotin, copper (e.g. as CuS04), zinc (e.g. as ZnS04), cobalt (e.g. as CoS04), selenium (e.g. as Na2Se03), iodine (e.g. as Kl), manganese (e.g. as MnS04) and/or calcium (e.g. as CaS04). The following non-limiting Examples are presented to better illustrate the invention.
Example 1 : Effect of Canthaxanthin on the productivity of layer hens (1st trial)
Experimental Design
In this study female layer chickens were used, all 35 weeks of age, and of Isa Brown lineage. The birds were housed together in their respective treatment groups as follows: Treatments
1 control, control + 2ppm , control + 4ppm, control + 8ppm Canthaxanthin Replicates
3 hens/replicate and 4 replicates/ treatment = 12 hens/treatment
Period of Experimentation
3 weeks of carotenoids administration. The laying rate was calculated weekly. The weighing of the eggs was carried out using a precision weighing scale (0.001 g).
Feeding
The diet given to the birds was a standard feed for layer hens (Mash fed ad libitum) with the addition of the product that was tested. The feed met all nutritional requirements in relation to the developmental stage of the birds and the recommendations in the layers' guide (Table 1 ).
TABLE 1 . Composition of feed used during the experiment
Vitamin and mineral premix supplies the following per kilogram of diet: vitamin A, 1000000 IU; vitamin D3, 300000 IU; vitamin E 3000 IU; vitamin K3 250 mg; vitamin B1 200 mg; vitamin B2 600 mg; vitamin B5 900 mg; vitamin B6 400 mg; folic acid 80mg; vitamin B12 2000 mg; niacin 3000 mg; biotin 13 mg; vitamin C 10000 mg; choline 25950 mg; iron 5000 mg; cupper 1000 mg; zinc 7000 mg; manganese 12000 mg; iodine 124 mg; cobalt 100 mg; selenium 19,8 mg,
TABLE 2. Treatments used in the experiment on layer hens for a period of three weeks.
Treatments Carophyll Red
(ppm)
1 0
2 2
3 4 Results
The results are shown in Figure 1 . The data show a good response for canthaxanthin. In particular the results show significantly more egg mass per cage over the 4 weeks period (p=0,0058). This leads to a 3% increase of egg mass per ppm canthaxanthin. Example 2: Effect of Canthaxanthin on the productivity of layer hens (2nd trial)
Experimental Design
In this study female layer chickens were used, all 38 weeks of age, and of Isa Brown lineage. The birds were housed together in their respective treatment groups as follows:
Treatments
1 control, control + 2,5ppm , control + 5ppm Canthaxanthin Replicates
3 hens/replicate and 4 replicates/ treatment = 12 hens/treatment Period of Experimentation
3 weeks of carotenoids administration. The laying rate was calculated weekly. The weighing of the eggs was carried out using a precision weighing scale (0.001 g).
Feeding
The diet given to the birds was a standard feed for layer hens (Mash fed ad libitum) with the addition of the product that was tested. The feed met all nutritional requirements in relation to the developmental stage of the birds and the recommendations in the layers' guide (Table 1 ). TABLE 1 . Composition of feed used during the experiment
Ingredient Percentage
Rice 21 ,8
Wheat 40,0
Oat 7,5
Soybean meal 50% 14,0
Vegetable Oil 2, 5 Ingredient Percentage
CaC03 7,8
DCP 1 ,3
(1 )
Vit & Mineral Premix 1 ,0
DL-Methionine -
NaCI 0,1
Fish Meal 4,0
Vitamin and mineral premix supplies the following per kilogram of diet: vitamin A, 1000000 IU; vitamin D3, 300000 IU; vitamin E 3000 IU; vitamin K3 250 mg; vitamin B1 200 mg; vitamin B2 600 mg; vitamin B5 900 mg; vitamin B6 400 mg; folic acid 80mg; vitamin B12 2000 mg; niacin 3000 mg; biotin 13 mg; vitamin C 10000 mg; choline 25950 mg; iron 5000 mg; cupper 1000 mg; zinc 7000 mg; manganese 12000 mg; iodine 124 mg; cobalt 100 mg; selenium 19,8 mg,
TABLE 2. Treatments used in the experiment on layer hens for a period of three weeks.
Results
The results are shown in Figure 2. The data show a good response for canthaxanthin. In particular it shows significantly more egg mass per cage over the 4 weeks period (p=0,0015). This leads to a 1 ,5% increase of egg mass per ppm canthaxanthin.
***

Claims

1 . The use of canthaxanthin for increasing egg mass of poultry layers.
2. The use according to claim 1 , wherein canthaxanthin is provided together with the feed in amounts from about 1 to 50 ppm canthaxanthin, preferably 2 to 10 ppm.
3. The use according to claim 1 , wherein canthaxanthin is administered in an aqueous solution.
4. The use according to claim 1 , wherein said poultry is a chicken.
5. A method of increasing egg production in a laying bird, comprising the administration of canthaxanthin to the bird in an amount sufficient to increase the average level of egg mass.
6. A method as recited in claim 1 , wherein canthaxanthin is administered in combination with a feed material suitable for consumption by a bird and wherein canthaxanthin is provided in amounts from about 1 to 50 ppm canthaxanthin, preferably 2 to 10 ppm.
7. A method as recited in claim 1 , wherein canthaxanthin is administered in an aqueous solution.
8. A method as recited in claim 1 , wherein said bird is a chicken.
EP15771638.2A 2014-10-10 2015-10-02 Use of canthaxanthin for laying hens Withdrawn EP3203859A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14188454 2014-10-10
PCT/EP2015/072764 WO2016055360A1 (en) 2014-10-10 2015-10-02 Use of canthaxanthin for laying hens

Publications (1)

Publication Number Publication Date
EP3203859A1 true EP3203859A1 (en) 2017-08-16

Family

ID=51690276

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15771638.2A Withdrawn EP3203859A1 (en) 2014-10-10 2015-10-02 Use of canthaxanthin for laying hens

Country Status (7)

Country Link
EP (1) EP3203859A1 (en)
JP (2) JP2017531623A (en)
CN (1) CN106793801A (en)
AU (1) AU2015330199A1 (en)
BR (1) BR112017006916A2 (en)
MX (1) MX2017004434A (en)
WO (1) WO2016055360A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115715536B (en) * 2022-11-30 2025-05-02 广东海洋大学 A method for improving the egg-laying performance of Huaixiang chicken breeders under high temperature environment

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
None *
See also references of WO2016055360A1 *

Also Published As

Publication number Publication date
CN106793801A (en) 2017-05-31
AU2015330199A1 (en) 2017-04-13
BR112017006916A2 (en) 2018-06-19
JP2020158488A (en) 2020-10-01
JP2017531623A (en) 2017-10-26
MX2017004434A (en) 2017-07-10
WO2016055360A1 (en) 2016-04-14

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