EP3136098A4 - Medium for resin particles containing fluorescent dye - Google Patents

Medium for resin particles containing fluorescent dye Download PDF

Info

Publication number
EP3136098A4
EP3136098A4 EP15783619.8A EP15783619A EP3136098A4 EP 3136098 A4 EP3136098 A4 EP 3136098A4 EP 15783619 A EP15783619 A EP 15783619A EP 3136098 A4 EP3136098 A4 EP 3136098A4
Authority
EP
European Patent Office
Prior art keywords
medium
resin particles
fluorescent dye
particles containing
containing fluorescent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP15783619.8A
Other languages
German (de)
French (fr)
Other versions
EP3136098A1 (en
EP3136098B1 (en
Inventor
Masaru Takahashi
Fuminori OKADA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Konica Minolta Inc
Original Assignee
Konica Minolta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Konica Minolta Inc filed Critical Konica Minolta Inc
Publication of EP3136098A1 publication Critical patent/EP3136098A1/en
Publication of EP3136098A4 publication Critical patent/EP3136098A4/en
Application granted granted Critical
Publication of EP3136098B1 publication Critical patent/EP3136098B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/16—Nitrogen-containing compounds
    • C08K5/34—Heterocyclic compounds having nitrogen in the ring
    • C08K5/3412—Heterocyclic compounds having nitrogen in the ring having one nitrogen atom in the ring
    • C08K5/3432—Six-membered rings
    • C08K5/3437—Six-membered rings condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/02—Use of particular materials as binders, particle coatings or suspension media therefor
    • C09K11/025—Use of particular materials as binders, particle coatings or suspension media therefor non-luminescent particle coatings or suspension media
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/14—Macromolecular compounds
    • C09K2211/1408—Carbocyclic compounds
    • C09K2211/1416—Condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/14—Macromolecular compounds
    • C09K2211/1408—Carbocyclic compounds
    • C09K2211/1433—Carbocyclic compounds bridged by heteroatoms, e.g. N, P, Si or B
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Optics & Photonics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
EP15783619.8A 2014-04-23 2015-04-15 Medium for resin particles containing fluorescent dye Active EP3136098B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014089287 2014-04-23
PCT/JP2015/061567 WO2015163209A1 (en) 2014-04-23 2015-04-15 Medium for resin particles containing fluorescent dye

Publications (3)

Publication Number Publication Date
EP3136098A1 EP3136098A1 (en) 2017-03-01
EP3136098A4 true EP3136098A4 (en) 2017-12-27
EP3136098B1 EP3136098B1 (en) 2020-12-09

Family

ID=54332376

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15783619.8A Active EP3136098B1 (en) 2014-04-23 2015-04-15 Medium for resin particles containing fluorescent dye

Country Status (4)

Country Link
US (5) US20170045452A1 (en)
EP (1) EP3136098B1 (en)
JP (1) JP6048597B2 (en)
WO (1) WO2015163209A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6048597B2 (en) * 2014-04-23 2016-12-21 コニカミノルタ株式会社 Preservation solution for fluorescent dye-containing resin particles
JP6447557B2 (en) * 2016-03-24 2019-01-09 日亜化学工業株式会社 Method for manufacturing light emitting device
WO2018185943A1 (en) 2017-04-07 2018-10-11 コニカミノルタ株式会社 Fluorescent premix particles, fluorescent stain containing same, and fluorescent staining method in which these are used
EP3608665A4 (en) * 2017-04-07 2020-04-22 Konica Minolta, Inc. Method for manufacturing purified product of protein-modified phosphor-integrated particle, method for manufacturing fluorescent staining liquid, purified product of protein-modified phosphor-integrated particle, and filter for purifying fluorescent staining liquid and protein-modified phosphor-integrated particle
JPWO2020075751A1 (en) * 2018-10-10 2021-09-30 コニカミノルタ株式会社 Luminescent dye-containing particles and labeling agents for pathological diagnosis
CN111289336B (en) * 2019-12-13 2023-06-13 山东源科生物科技股份有限公司 Fungus fluorescent staining solution and preparation method thereof
JPWO2021182228A1 (en) * 2020-03-10 2021-09-16

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0581881A1 (en) * 1991-04-02 1994-02-09 Terrapin Technologies, Inc. Method for analyte classification by sc profiles
EP0596098A1 (en) * 1992-05-13 1994-05-11 Molecular Probes, Inc. Fluorescent microparticles with controllable enhanced stokes shift
DE69017753T2 (en) * 1989-05-18 1995-07-13 Yeda Research And Development Co., Ltd., Rehovot Tumor necrosis factor binding protein II, its purification and specific antibodies.
EP2531569A2 (en) * 2010-02-02 2012-12-12 Ventana Medical Systems, Inc. Composition and method for stabilizing fluorescent particles
WO2014203614A1 (en) * 2013-06-19 2014-12-24 コニカミノルタ株式会社 Fluorescent nanoparticles for biomolecular staining and manufacturing method for same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8927503D0 (en) 1989-12-04 1990-02-07 Kronem Systems Inc Enzyme-amplified lanthanide chelate luminescence
ATE395598T1 (en) 1998-04-14 2008-05-15 Otsuka Pharma Co Ltd METHOD AND DEVICE FOR DETECTING ANTIBODIES
EP3225990B1 (en) 2010-08-30 2020-07-08 Konica Minolta, Inc. Particle for staining a tissue
US10031139B2 (en) * 2012-03-30 2018-07-24 Konica Minolta, Inc. Method for detecting biological material
JP6048597B2 (en) * 2014-04-23 2016-12-21 コニカミノルタ株式会社 Preservation solution for fluorescent dye-containing resin particles

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69017753T2 (en) * 1989-05-18 1995-07-13 Yeda Research And Development Co., Ltd., Rehovot Tumor necrosis factor binding protein II, its purification and specific antibodies.
EP0581881A1 (en) * 1991-04-02 1994-02-09 Terrapin Technologies, Inc. Method for analyte classification by sc profiles
EP0596098A1 (en) * 1992-05-13 1994-05-11 Molecular Probes, Inc. Fluorescent microparticles with controllable enhanced stokes shift
EP2531569A2 (en) * 2010-02-02 2012-12-12 Ventana Medical Systems, Inc. Composition and method for stabilizing fluorescent particles
WO2014203614A1 (en) * 2013-06-19 2014-12-24 コニカミノルタ株式会社 Fluorescent nanoparticles for biomolecular staining and manufacturing method for same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "Drug Discovery Research Clinical Screening Assay Buffers for DELFIA", 1 January 2002 (2002-01-01), pages 1 - 2, XP055424920, Retrieved from the Internet <URL:https://www.perkinelmer.com/lab-solutions/resources/docs/GDE_DELFIABuffers.pdf> [retrieved on 20171114] *
See also references of WO2015163209A1 *

Also Published As

Publication number Publication date
US20230069563A1 (en) 2023-03-02
US20200003690A1 (en) 2020-01-02
US20170045452A1 (en) 2017-02-16
JP6048597B2 (en) 2016-12-21
JPWO2015163209A1 (en) 2017-04-13
WO2015163209A1 (en) 2015-10-29
US11346784B2 (en) 2022-05-31
US20210381982A1 (en) 2021-12-09
US20200003689A1 (en) 2020-01-02
EP3136098A1 (en) 2017-03-01
EP3136098B1 (en) 2020-12-09

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