EP3033150A4 - Administration of karenitecin for the treatment of advanced ovarian cancer, including chemotherapy-resistant and/or the mucinous adenocarcinoma sub-types - Google Patents

Administration of karenitecin for the treatment of advanced ovarian cancer, including chemotherapy-resistant and/or the mucinous adenocarcinoma sub-types Download PDF

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Publication number
EP3033150A4
EP3033150A4 EP14836702.2A EP14836702A EP3033150A4 EP 3033150 A4 EP3033150 A4 EP 3033150A4 EP 14836702 A EP14836702 A EP 14836702A EP 3033150 A4 EP3033150 A4 EP 3033150A4
Authority
EP
European Patent Office
Prior art keywords
karenitecin
administration
resistant
types
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14836702.2A
Other languages
German (de)
French (fr)
Other versions
EP3033150A1 (en
Inventor
Frederick H. Hausheer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crown Bioscience Inc
Original Assignee
BioNumerik Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BioNumerik Pharmaceuticals Inc filed Critical BioNumerik Pharmaceuticals Inc
Publication of EP3033150A1 publication Critical patent/EP3033150A1/en
Publication of EP3033150A4 publication Critical patent/EP3033150A4/en
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP14836702.2A 2013-08-13 2014-08-10 Administration of karenitecin for the treatment of advanced ovarian cancer, including chemotherapy-resistant and/or the mucinous adenocarcinoma sub-types Withdrawn EP3033150A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361865360P 2013-08-13 2013-08-13
PCT/US2014/050463 WO2015023551A1 (en) 2013-08-13 2014-08-10 Administration of karenitecin for the treatment of advanced ovarian cancer, including chemotherapy-resistant and/or the mucinous adenocarcinoma sub-types

Publications (2)

Publication Number Publication Date
EP3033150A1 EP3033150A1 (en) 2016-06-22
EP3033150A4 true EP3033150A4 (en) 2017-06-28

Family

ID=52468603

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14836702.2A Withdrawn EP3033150A4 (en) 2013-08-13 2014-08-10 Administration of karenitecin for the treatment of advanced ovarian cancer, including chemotherapy-resistant and/or the mucinous adenocarcinoma sub-types

Country Status (2)

Country Link
EP (1) EP3033150A4 (en)
WO (3) WO2015023553A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013067050A1 (en) 2011-10-31 2013-05-10 University Of Utah Research Foundation Genetic alterations in glioblastoma
US20180301223A1 (en) * 2015-04-14 2018-10-18 University Of Utah Research Foundation Advanced Tensor Decompositions For Computational Assessment And Prediction From Data
CN105198790B (en) * 2015-04-20 2018-02-16 范国煌 Promote the tetracyclic compound of double negative t cells in-vitro multiplication
EP3199641B1 (en) * 2016-01-27 2021-09-29 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Means and methods for staging, typing and treating a cancerous disease
CN107058315B (en) 2016-12-08 2019-11-08 上海优卡迪生物医药科技有限公司 Strike the siRNA for subtracting people PD-1, recombinant expression CAR-T carrier and its construction method and application
AU2018289369A1 (en) * 2017-06-20 2020-01-16 Nantomics, Llc Use of cell-free circulating rna (cfRNA) expression of PD-L1 and ERCC1 in plasma to monitor response to therapy in NSCLC
CN113461952B (en) * 2021-06-30 2022-07-01 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） Active oxygen response type self-degradation polymer and preparation method and application thereof
CN118103949A (en) * 2021-09-15 2024-05-28 英飞凌科技有限责任公司 Method for integrating SONOS into HKMG stream

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005113018A2 (en) * 2004-04-27 2005-12-01 Wellstat Biologics Corporation Cancer treatment using viruses and camptothecins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8293726B2 (en) * 2005-12-02 2012-10-23 Vianova Labs, Inc. Treatment of cancer and other diseases
US9023805B2 (en) * 2010-09-16 2015-05-05 Bionumerik Pharmaceuticals, Inc. Increasing cancer patient survival time by administration of dithio-containing compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005113018A2 (en) * 2004-04-27 2005-12-01 Wellstat Biologics Corporation Cancer treatment using viruses and camptothecins

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANNEMARIE H. VAN HATTUM ET AL: "New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer", INTERNATIONAL JOURNAL OF CANCER, vol. 88, no. 2, 15 October 2000 (2000-10-15), pages 260 - 266, XP055007980, ISSN: 0020-7136, DOI: 10.1002/1097-0215(20001015)88:2<260::AID-IJC18>3.0.CO;2-Q *
MUNSTER PAMELA N ET AL: "Preclinical and clinical activity of the topoisomerase I inhibitor, karenitecin, in melanoma", EXPERT OPINION ON INVESTIGATIONAL DRUGS, vol. 20, no. 11, November 2011 (2011-11-01), pages 1565 - 1574, XP002766330 *
NAUMANN R WENDEL ET AL: "Management Strategies for Recurrent Platinum-Resistant Ovarian Cancer", DRUGS, ADIS INTERNATIONAL LTD, NZ, vol. 71, no. 11, 1 January 2011 (2011-01-01), pages 1397 - 1412, XP009165133, ISSN: 0012-6667, DOI: 10.2165/11591720-000000000-00000 *
See also references of WO2015023551A1 *

Also Published As

Publication number Publication date
WO2015023551A1 (en) 2015-02-19
WO2015023552A1 (en) 2015-02-19
WO2015023553A3 (en) 2015-04-23
EP3033150A1 (en) 2016-06-22
WO2015023553A2 (en) 2015-02-19

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Effective date: 20160310

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Extension state: BA ME

RIN1 Information on inventor provided before grant (corrected)

Inventor name: HAUSHEER, FREDERICK H.

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 45/06 20060101ALI20170130BHEP

Ipc: A61K 31/185 20060101ALI20170130BHEP

Ipc: A61K 31/4745 20060101AFI20170130BHEP

Ipc: A61P 35/00 20060101ALI20170130BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20170526

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 45/06 20060101ALI20170519BHEP

Ipc: A61K 31/185 20060101ALI20170519BHEP

Ipc: A61K 31/4745 20060101AFI20170519BHEP

Ipc: A61P 35/00 20060101ALI20170519BHEP

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 35/00 20060101ALI20170614BHEP

Ipc: A61K 31/185 20060101ALI20170614BHEP

Ipc: A61K 31/4745 20060101AFI20170614BHEP

Ipc: A61K 45/06 20060101ALI20170614BHEP

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CROWN BIOSCIENCE, INC.

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Effective date: 20190817