EP3029043A4 - Tricyclic benzoxaborole compound, preparation method therefor, and use thereof - Google Patents

Tricyclic benzoxaborole compound, preparation method therefor, and use thereof Download PDF

Info

Publication number
EP3029043A4
EP3029043A4 EP14831789.4A EP14831789A EP3029043A4 EP 3029043 A4 EP3029043 A4 EP 3029043A4 EP 14831789 A EP14831789 A EP 14831789A EP 3029043 A4 EP3029043 A4 EP 3029043A4
Authority
EP
European Patent Office
Prior art keywords
preparation
method therefor
benzoxaborole compound
tricyclic benzoxaborole
tricyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP14831789.4A
Other languages
German (de)
French (fr)
Other versions
EP3029043B1 (en
EP3029043A1 (en
Inventor
Soon-Hoe Kim
Weon-Bin Im
Seung-Bum Ha
Jung-Sang Park
Mi-Yeon Kim
Sung-Hak Choi
Hyun-Jung Sung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dong A ST Co Ltd
Dong-A ST Co Ltd
Original Assignee
Dong A ST Co Ltd
Dong-A ST Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong A ST Co Ltd, Dong-A ST Co Ltd filed Critical Dong A ST Co Ltd
Publication of EP3029043A1 publication Critical patent/EP3029043A1/en
Publication of EP3029043A4 publication Critical patent/EP3029043A4/en
Application granted granted Critical
Publication of EP3029043B1 publication Critical patent/EP3029043B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EP14831789.4A 2013-07-30 2014-07-28 Tricyclic benzoxaborole compound, preparation method therefor, and use thereof Active EP3029043B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20130090493 2013-07-30
KR1020140093765A KR101636431B1 (en) 2013-07-30 2014-07-24 Tricyclic benzoxaborole compound, process preparing thereof and use thereof
PCT/KR2014/006894 WO2015016558A1 (en) 2013-07-30 2014-07-28 Tricyclic benzoxaborole compound, preparation method therefor, and use thereof

Publications (3)

Publication Number Publication Date
EP3029043A1 EP3029043A1 (en) 2016-06-08
EP3029043A4 true EP3029043A4 (en) 2017-04-05
EP3029043B1 EP3029043B1 (en) 2018-08-29

Family

ID=52571626

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14831789.4A Active EP3029043B1 (en) 2013-07-30 2014-07-28 Tricyclic benzoxaborole compound, preparation method therefor, and use thereof

Country Status (17)

Country Link
US (1) US9676796B2 (en)
EP (1) EP3029043B1 (en)
JP (1) JP6130600B2 (en)
KR (1) KR101636431B1 (en)
CN (1) CN105452259B (en)
AU (1) AU2014297102B2 (en)
BR (1) BR112016001876B1 (en)
CA (1) CA2918249C (en)
ES (1) ES2688597T3 (en)
HK (1) HK1218120A1 (en)
IL (1) IL243699A0 (en)
MX (1) MX363530B (en)
NZ (1) NZ716154A (en)
PT (1) PT3029043T (en)
RU (1) RU2639153C2 (en)
SG (1) SG11201600563UA (en)
WO (1) WO2015016558A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11039617B2 (en) 2013-01-30 2021-06-22 Agrofresh Inc. Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
US10070649B2 (en) 2013-01-30 2018-09-11 Agrofresh Inc. Volatile applications against pathogens
PE20160752A1 (en) 2013-08-09 2016-08-17 Anacor Pharmaceuticals Inc TRICYCLIC BENZOXABOROL COMPOUNDS AND USES OF THEM
WO2016001834A1 (en) 2014-07-01 2016-01-07 Daiichi Sankyo Company, Limited Tricyclic benzoxaboroles as antibacterial agents
MA41494B1 (en) 2015-02-12 2020-10-28 Glaxosmithkline Ip No 2 Ltd Benzoxaborole compounds substituted in position 4 and associated uses
RS64770B1 (en) 2016-03-07 2023-11-30 Agrofresh Inc Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops
CN113214302B (en) * 2021-04-23 2022-06-24 四川大学 3-substituted five-membered cyclic borate derivative for inhibiting metal beta-lactamase and/or serine beta-lactamase
CA3239096A1 (en) * 2022-06-23 2023-12-28 Shanghai Micurx Pharmaceutical Co., Ltd. Methods and uses of boron compounds in the treatment of nontuberculous mycobacterium infections and pharmaceutical compositions for treatment of same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007095638A2 (en) * 2006-02-16 2007-08-23 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-inflammatory agents
WO2008157726A1 (en) * 2007-06-20 2008-12-24 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US20130165411A1 (en) * 2011-12-22 2013-06-27 Micurx Pharmaceuticals, Inc. Tricyclic boron compounds for antimicrobial therapy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7390806B2 (en) 2002-12-18 2008-06-24 Anacor Pharmaceuticals, Inc. Antibiotics containing borinic acid complexes and methods of use
RU2397986C2 (en) 2002-12-18 2010-08-27 Анакор Фармасьютикалз, Инк. Antibiotics containing borinic acid complexes and methods of obtaining them
EP2987796B1 (en) 2005-02-16 2018-08-08 Anacor Pharmaceuticals, Inc. Halogen-substituted boronophthalides for the treatment of infections
RU2008131324A (en) 2005-12-30 2010-02-10 Анакор Фармасьютикалз, Инк. (Us) WOODEN SMALL MOLECULES
KR100925333B1 (en) 2008-03-14 2009-11-04 엘지전자 주식회사 Method of performing uplink synchronization in random access procedure
WO2009140309A2 (en) 2008-05-12 2009-11-19 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US20110212918A1 (en) 2009-11-11 2011-09-01 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
SG184268A1 (en) 2010-04-07 2012-10-30 Glaxosmithkline Llc Process for preparing benzoxaboroles
EP2613788B1 (en) 2010-09-07 2017-06-21 Anacor Pharmaceuticals, Inc. Benzoxaborole derivatives for treating bacterial infections
PE20160752A1 (en) 2013-08-09 2016-08-17 Anacor Pharmaceuticals Inc TRICYCLIC BENZOXABOROL COMPOUNDS AND USES OF THEM

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007095638A2 (en) * 2006-02-16 2007-08-23 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-inflammatory agents
WO2008157726A1 (en) * 2007-06-20 2008-12-24 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US20130165411A1 (en) * 2011-12-22 2013-06-27 Micurx Pharmaceuticals, Inc. Tricyclic boron compounds for antimicrobial therapy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2015016558A1 *

Also Published As

Publication number Publication date
ES2688597T3 (en) 2018-11-05
KR20150014858A (en) 2015-02-09
IL243699A0 (en) 2016-04-21
CN105452259A (en) 2016-03-30
AU2014297102A1 (en) 2016-02-04
RU2016103919A (en) 2017-08-31
CA2918249A1 (en) 2015-02-05
EP3029043B1 (en) 2018-08-29
JP6130600B2 (en) 2017-05-17
EP3029043A1 (en) 2016-06-08
US9676796B2 (en) 2017-06-13
NZ716154A (en) 2017-08-25
BR112016001876B1 (en) 2022-02-22
SG11201600563UA (en) 2016-02-26
BR112016001876A2 (en) 2017-08-01
MX2016001138A (en) 2016-04-29
RU2639153C2 (en) 2017-12-20
US20160168167A1 (en) 2016-06-16
KR101636431B1 (en) 2016-07-05
JP2016530250A (en) 2016-09-29
AU2014297102B2 (en) 2017-02-23
PT3029043T (en) 2018-10-26
CA2918249C (en) 2018-05-08
HK1218120A1 (en) 2017-02-03
CN105452259B (en) 2018-01-12
MX363530B (en) 2019-03-27
WO2015016558A1 (en) 2015-02-05

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