EP3025355A1 - Creation d'isotopes par faisceaux laser - Google Patents
Creation d'isotopes par faisceaux laserInfo
- Publication number
- EP3025355A1 EP3025355A1 EP14750565.5A EP14750565A EP3025355A1 EP 3025355 A1 EP3025355 A1 EP 3025355A1 EP 14750565 A EP14750565 A EP 14750565A EP 3025355 A1 EP3025355 A1 EP 3025355A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- target
- particles
- laser beams
- isotopes
- plasma condition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000002245 particle Substances 0.000 claims abstract description 47
- 238000000034 method Methods 0.000 claims abstract description 26
- 238000006243 chemical reaction Methods 0.000 claims abstract description 24
- 230000003993 interaction Effects 0.000 claims abstract description 11
- 239000000446 fuel Substances 0.000 claims abstract description 10
- 230000001360 synchronised effect Effects 0.000 claims abstract description 8
- 239000007787 solid Substances 0.000 claims description 11
- 238000011084 recovery Methods 0.000 claims description 7
- 230000008569 process Effects 0.000 claims description 5
- 230000003750 conditioning effect Effects 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 238000004590 computer program Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 description 15
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 5
- 229910052796 boron Inorganic materials 0.000 description 5
- OKTJSMMVPCPJKN-BJUDXGSMSA-N carbon-11 Chemical compound [11C] OKTJSMMVPCPJKN-BJUDXGSMSA-N 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000001678 irradiating effect Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- QJGQUHMNIGDVPM-BJUDXGSMSA-N Nitrogen-13 Chemical compound [13N] QJGQUHMNIGDVPM-BJUDXGSMSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- YCKRFDGAMUMZLT-BJUDXGSMSA-N fluorine-18 atom Chemical compound [18F] YCKRFDGAMUMZLT-BJUDXGSMSA-N 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- QVGXLLKOCUKJST-BJUDXGSMSA-N oxygen-15 atom Chemical compound [15O] QVGXLLKOCUKJST-BJUDXGSMSA-N 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
- G21G1/10—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by bombardment with electrically charged particles
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
- G21G1/06—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by neutron irradiation
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
- G21G1/12—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by electromagnetic irradiation, e.g. with gamma or X-rays
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H1/00—Generating plasma; Handling plasma
- H05H1/0006—Investigating plasma, e.g. measuring the degree of ionisation or the electron temperature
- H05H1/0012—Investigating plasma, e.g. measuring the degree of ionisation or the electron temperature using electromagnetic or particle radiation, e.g. interferometry
- H05H1/0043—Investigating plasma, e.g. measuring the degree of ionisation or the electron temperature using electromagnetic or particle radiation, e.g. interferometry by using infrared or ultraviolet radiation
Definitions
- the present invention relates to a method and system for creating isotopes by plasma laser beams.
- Plasma is a partially or completely ionized medium, composed of ions and electrons, with no presupposition of temperature and / or equilibrium.
- the isotopes created can be stable or unstable isotopes, then called radioisotopes, in their state of fundamental or excited energy, then called nuclear isomers. For the rest of the text, they will be grouped under the term "isotopes".
- isotopes are used in medicine for diagnostics and therapies. They can also be used for other scientific or industrial applications, for example for product tracing.
- isotopes are usually produced by particle accelerators, circular (cyclotrons) or linear, or in nuclear reactors.
- US 6,909,764 discloses a method for creating isotopes, in which a target is bombarded by particles generated using a laser beam. Isotopes are created by nuclear reactions produced by the interaction between the target and the particles.
- the use of a laser beam reduces the size and cost of the isotope creation system. It is thus possible to install the isotope creation system near their place of use, eliminating the problem of transport, which is particularly interesting for short-lived isotopes.
- PET positron emission
- the invention proposes a method for creating isotopes by laser beams, comprising steps:
- the fuel and the particles being chosen so that the interaction between the target in the plasma condition and the particles produces nuclear reactions
- Step / 2 / can be repeated one or more times on the same target.
- a characteristic duration of the pulses produced by the set of laser beams is for example between 50 femtoseconds and 300 picoseconds.
- Step / 2 / may comprise an operation for producing the particles by irradiating a second solid target, solid structured, gaseous or liquid, by the set of laser beams.
- the set of laser beams used to bombard the target is a first set of laser beams, the target being set in plasma condition using a second set of laser beams synchronized with the first.
- a characteristic duration of the pulses produced by the second set of laser beams is for example between one picosecond and twenty nanoseconds.
- the target is placed in plasma condition using a machine with axial necking.
- the target comprises a hollow, the particles bombarding the target inside the hollow.
- the target is disposed in an envelope having an opening, the particles bombarding the target through the opening
- the fuel and the particles can be chosen so that the interaction between the target in the plasma condition and the particles produces nuclear chain reactions.
- the invention also proposes a computer program comprising instructions for the implementation of the method when this program is executed by a processor.
- the invention also proposes a system for creating isotopes by laser beams, comprising:
- / l / ionization means configured to set a target in a plasma condition, / 2 / a set of laser beams configured to irradiate the target in plasma condition by particles, the laser beam assembly being synchronized with the means ionization, the fuel and the particles being chosen so that the irradiation of the target in plasma condition by the particles produces nuclear reactions,
- isotope recovery means configured to recover isotopes generated by the nuclear reactions.
- Figure 1 is a block diagram showing an isotope creation system according to one embodiment of the invention
- Figure 2 is a flowchart illustrating the steps of a laser beam isotope creation method according to an embodiment of the invention.
- Figure 1 shows a system for creating isotopes by laser beams.
- Isotopes can be stable isotopes, radioisotopes, or nuclear isomers.
- the system comprises a first set of laser beams 1 configured to allow irradiation of a target 2 in a plasma condition by a particle beam 3.
- Target 2 can have different forms. According to the embodiment of the invention shown in Figure 1, the target 2 is disposed in an envelope 4 having an opening.
- the target 2 comprises a hollow.
- the particles include ions and electrons.
- the first set of laser beams 1 may comprise one or more laser beams. In Figure 1, three beams have been shown.
- a characteristic duration of the pulses produced by the laser beams 1 is for example between 50 femtoseconds and 300 picoseconds.
- the intensity, the wavelength, the duration and the shape of the pulses produced by the laser beams 1 are furthermore determined so that the bombardment particles have an energy which is close to or greater than that of the resonances of the laser beam. cross section of the nuclear reaction considered. Higher energy makes it possible to take into account the energy losses associated with the crossing of the plasma surrounding the target 2.
- the intensity of the laser beams 1 is for example of the order of, or greater than, 18 W / cm 2 .
- the system also comprises ionization means 5, configured to put the target 2 in plasma condition.
- the ionization means comprise a second set of laser beams 5.
- the second set of laser beams 5 may comprise one or more laser beams.
- two laser beams have been shown.
- the pulses that are produced by the second set of laser beams 5 have a characteristic duration between one picosecond and twenty nanoseconds.
- the intensity of the laser beams 5 is for example of the order of 10 12 -10 15 W / cm 2 .
- the ionization means 5 comprise a machine with axial necking (Z-pinch).
- the system also comprises synchronization means 7, configured to synchronize the first set of laser beams 1 and the ionization means 5.
- synchronization means 7 configured to synchronize the first set of laser beams 1 and the ionization means 5.
- the system also includes isotope recovery means (not shown) configured to recover isotopes generated by nuclear reactions.
- the steps of a method for creating isotopes by laser beams are described below.
- the method can be implemented by the system described above.
- the method comprises: a synchronization initialization step S1, a target conditioning step S2 of a target 2,
- step S1 the synchronization means 7 are started, so as to control the instants of realization of the steps S2 to S4.
- the creation of the plasma and its bombardment by the particles 3 must be synchronized. In the embodiment of the invention shown, this can be achieved by synchronizing the first and second sets of laser beams 1, 5.
- step S2 the target 2 is put in plasma condition.
- Target 2 can be solid, structured solid, gaseous or liquid.
- step S3 the particles 3 are generated by irradiating a second target 6 with the first set of laser beams 1.
- the initial state of the target 6 may be solid, structured solid, gaseous or liquid.
- the target 6 is for example a metal sheet of limited thickness.
- step S4 the target 2 in the plasma condition is bombarded by the particles 3.
- the fuel and the particles are chosen so that the interaction between the target 2 in the plasma condition and the particle beam 3 produces nuclear reactions.
- the fuel and the particles are selected so that the interaction between the target 2 in the plasma condition and the particle beam 3 produces nuclear chain reactions.
- the production of nuclear chain reactions increases the production of isotopes.
- the electrons of the particle beam 3 interact with the target 2, in parallel with the interaction between the ions of the particle beam 3 and the target 2 This double interaction also makes it possible to increase the production of isotopes.
- the particles 3 bombard the target 2 inside the hollow.
- the particles 3 bombard the target 2 through the opening.
- Step S4 may be repeated one or more times on the same target 2.
- the accumulation of laser shots on the same target 2 increases the production of isotopes.
- the repetition rate is for example of the order of 10 3 Hz.
- step S5 isotopes generated by the nuclear reactions are recovered.
- the isotopes can be recovered directly from the target, in particular when they have been confined in the target 2 or in the envelope 4. The recovery is thus facilitated.
- an isotope recovery device is disposed near the target 2. Calculations and first experimental results show a sharp increase in reaction rates when target 2 is in plasma condition, leading to much higher isotope production efficiencies than currently proposed laser methods. Moreover, thanks to the process, the emission zone is denser and smaller, which facilitates the recovery of isotopes.
- the isotopes created can be stable isotopes, radioisotopes, or nuclear isomers, depending on the applications considered.
- This process makes it possible in particular to produce the carbon 11 isotope ( 1: L C) from the nuclear reaction 14 N (p, a) 1: L C produced by a proton beam (p) bombarding a target 2 containing Nitrogen 14 ( 14 N), or from the nuclear reaction 11 B (p, n) 11 C by bombarding a target containing boron 1: L B by protons.
- isotopes such as Fluorine 18 ( 18 F), Nitrogen 13 ( 13 N), and Oxygen 15 ( 15 O)
- the isotopes created depend on the fuel 2 and the particles 3 used.
- the first set of laser beams 1 comprises in this example a laser beam producing a laser pulse delivering 20J in lps at wavelength 0.53 ⁇ .
- the laser beam 1 is focused on an aluminum sheet 6 of 20 ⁇ of initial thickness.
- the generated beam of particles 3 is a beam of energetic protons. Protons having an exponentially decreasing energy spectrum with a maximum energy of about 12 MeV are sent on a natural boron target 2 (20% of 10 B and 80% of 1: L B) transformed into plasma just before the arrival of the proton beam.
- Plasma conditioning is performed by another laser beam 5 delivering 300J in 1.5ns at wavelength 0.53 ⁇ .
- Carbon 11 ( 1: L C) produced on a boron target by reaction 11 B (p, n) 11 C is measured after firing by activation of target 2.
- the 1 C product is then measured in the target 2.
- a solid boron target is also bombarded by a proton beam under the same conditions.
- the method and system described above thus allow the realization of less expensive, more efficient and site-based facilities, particularly for the production of isotopes for diagnostic purposes and therapy in medicine.
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Electron Sources, Ion Sources (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Description
Claims
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1357192A FR3008822B1 (fr) | 2013-07-22 | 2013-07-22 | Creation d'isotopes par faisceaux laser |
| PCT/FR2014/051819 WO2015011370A1 (fr) | 2013-07-22 | 2014-07-15 | Creation d'isotopes par faisceaux laser |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP3025355A1 true EP3025355A1 (fr) | 2016-06-01 |
Family
ID=49713172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP14750565.5A Withdrawn EP3025355A1 (fr) | 2013-07-22 | 2014-07-15 | Creation d'isotopes par faisceaux laser |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10217538B2 (fr) |
| EP (1) | EP3025355A1 (fr) |
| FR (1) | FR3008822B1 (fr) |
| WO (1) | WO2015011370A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10468148B2 (en) * | 2017-04-24 | 2019-11-05 | Infineon Technologies Ag | Apparatus and method for neutron transmutation doping of semiconductor wafers |
| CA3187498A1 (fr) * | 2020-07-30 | 2022-02-03 | Krishnan Venkatakrishnan | Synthese laser ultracourte de nanoparticules d'isotopes |
| CZ309802B6 (cs) * | 2021-04-16 | 2023-10-25 | Extreme Light Infrastructure ERIC (ELI ERIC) | Jaderný terčík, způsob indukce jaderné reakce s tímto jaderným terčíkem a zařízení na výrobu radioizotopů s tímto jaderným terčíkem |
| CN117413322B (zh) | 2021-04-16 | 2025-09-30 | 极光基础设施埃里克 | 一种核靶、用于诱导核反应的方法以及适用于实施该方法的装置 |
| WO2023101745A2 (fr) * | 2021-09-09 | 2023-06-08 | NU Planet Holding Co. | Générateur de radio-isotopes, appareil, système et procédé |
| HUP2100387A1 (hu) * | 2021-11-09 | 2023-05-28 | Wigner Fizikai Kutatokoezpont | Eljárás izotópok elõállítására plazmonikus erõsítéssel segített nagyenergiás lézerimpulzusokkal |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3778585A (en) * | 1972-04-21 | 1973-12-11 | Battelle Memorial Institute | Protection device for preventing damage to radiation source from backscatter |
| US4504964A (en) * | 1982-09-20 | 1985-03-12 | Eaton Corporation | Laser beam plasma pinch X-ray system |
| US4704718A (en) * | 1985-11-01 | 1987-11-03 | Princeton University | Apparatus and method for generating soft X-ray lasing action in a confined plasma column through the use of a picosecond laser |
| CA2325362A1 (fr) * | 2000-11-08 | 2002-05-08 | Kirk Flippo | Methode et appareil pour produire des particules de haute energie et amorcer des reactions nucleaires |
| JP2002289397A (ja) * | 2001-03-23 | 2002-10-04 | Takayasu Mochizuki | レーザプラズマ発生方法およびそのシステム |
| EP1453063A1 (fr) * | 2003-02-28 | 2004-09-01 | Euratom | Méthode pour produire de l'actinium-225 |
| EP1569243A1 (fr) * | 2004-02-20 | 2005-08-31 | Ion Beam Applications S.A. | Dispositif de cible pour la production d'un radioisotope |
| JP5629089B2 (ja) * | 2009-12-16 | 2014-11-19 | 浜松ホトニクス株式会社 | 核融合ターゲット材、核融合装置、及び核融合方法 |
-
2013
- 2013-07-22 FR FR1357192A patent/FR3008822B1/fr not_active Expired - Fee Related
-
2014
- 2014-07-15 EP EP14750565.5A patent/EP3025355A1/fr not_active Withdrawn
- 2014-07-15 US US14/906,951 patent/US10217538B2/en not_active Expired - Fee Related
- 2014-07-15 WO PCT/FR2014/051819 patent/WO2015011370A1/fr not_active Ceased
Non-Patent Citations (2)
| Title |
|---|
| None * |
| See also references of WO2015011370A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| FR3008822B1 (fr) | 2015-09-18 |
| US10217538B2 (en) | 2019-02-26 |
| WO2015011370A1 (fr) | 2015-01-29 |
| FR3008822A1 (fr) | 2015-01-23 |
| US20160172065A1 (en) | 2016-06-16 |
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