EP2951321A4 - Synthesis and enrichment of nucleic acid sequences - Google Patents

Synthesis and enrichment of nucleic acid sequences

Info

Publication number
EP2951321A4
EP2951321A4 EP14861883.8A EP14861883A EP2951321A4 EP 2951321 A4 EP2951321 A4 EP 2951321A4 EP 14861883 A EP14861883 A EP 14861883A EP 2951321 A4 EP2951321 A4 EP 2951321A4
Authority
EP
European Patent Office
Prior art keywords
enrichment
synthesis
nucleic acid
acid sequences
sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14861883.8A
Other languages
German (de)
French (fr)
Other versions
EP2951321A2 (en
Inventor
Jason Poole
Saege Hancock
Karena Kosco
Vlada Melnikova
Peter Croucher
Tim Lu
Mark G Erlander
Errin Samuelsz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiff Oncology Inc
Original Assignee
Trovagene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trovagene Inc filed Critical Trovagene Inc
Priority claimed from PCT/US2014/061435 external-priority patent/WO2015073163A2/en
Publication of EP2951321A2 publication Critical patent/EP2951321A2/en
Publication of EP2951321A4 publication Critical patent/EP2951321A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP14861883.8A 2013-10-20 2014-10-20 Synthesis and enrichment of nucleic acid sequences Withdrawn EP2951321A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361893283P 2013-10-20 2013-10-20
US201361904141P 2013-11-14 2013-11-14
US201462039905P 2014-08-20 2014-08-20
PCT/US2014/061435 WO2015073163A2 (en) 2013-11-14 2014-10-20 Synthesis and enrichment of nucleic acid sequences

Publications (2)

Publication Number Publication Date
EP2951321A2 EP2951321A2 (en) 2015-12-09
EP2951321A4 true EP2951321A4 (en) 2016-11-09

Family

ID=54361247

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14861883.8A Withdrawn EP2951321A4 (en) 2013-10-20 2014-10-20 Synthesis and enrichment of nucleic acid sequences

Country Status (2)

Country Link
EP (1) EP2951321A4 (en)
HK (1) HK1211628A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012075231A1 (en) * 2010-12-03 2012-06-07 Brandeis University Methods and kits for detecting nucleic acid mutants in wild-type populations
WO2012162613A2 (en) * 2011-05-26 2012-11-29 Brandeis University Detection of sequence variants in the human epidermal growth factor receptor (egfr) gene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012075231A1 (en) * 2010-12-03 2012-06-07 Brandeis University Methods and kits for detecting nucleic acid mutants in wild-type populations
WO2012162613A2 (en) * 2011-05-26 2012-11-29 Brandeis University Detection of sequence variants in the human epidermal growth factor receptor (egfr) gene

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOHN MORLAN ET AL: "Mutation Detection by Real-Time PCR: A Simple, Robust and Highly Selective Method", PLOS ONE, vol. 4, no. 2, 25 February 2009 (2009-02-25), pages e4584, XP055111534, DOI: 10.1371/journal.pone.0004584 *
WANG HAIYING ET AL: "Allele-Specific, Non-Extendable Primer Blocker PCR (AS-NEPB-PCR) for DNA Mutation Detection in Cancer", JOURNAL OF MOLECULAR DIAGNOSTICS,THE, AMERICAN SOCIETY FOR INVESTIGATIVE PATHOLOGY, US, vol. 15, no. 1, 1 January 2013 (2013-01-01), pages 62 - 69, XP009166207, ISSN: 1525-1578, DOI: 10.1016/J.JMOLDX.2012.08.007 *

Also Published As

Publication number Publication date
HK1211628A1 (en) 2016-05-27
EP2951321A2 (en) 2015-12-09

Similar Documents

Publication Publication Date Title
HK1255869A1 (en) Methods of sequencing the immune repertoire
HK1219503A1 (en) Methods and compositions for nucleic acid sequencing
HK1222466A1 (en) Analysis of genetic variants
HK1213023A1 (en) Compositions and methods of nucleic acid-targeting nucleic acids
HK1226105B (en) Improved methods of nucleic acid sequencing
SG11201603144QA (en) Artificial nucleic acid molecules
HUE045954T2 (en) Methods and compositions for preparing nucleic acid libraries
EP2922989A4 (en) Methods for standardized sequencing of nucleic acids and uses thereof
EP2912178A4 (en) Super-enhancers and methods of use thereof
EP2844903A4 (en) Tubes and methods of production and use thereof
HK1221227A1 (en) Methods and compositions for nanostructure-based nucleic acid sequencing
SG11201603028SA (en) Purification of proteins
GB201419367D0 (en) Nucleic acid probe
HK1224307A1 (en) Protoxin-ii variants and methods of use -ii
SG11201602291TA (en) Nucleic acid biomarker and use thereof
HK1222201A1 (en) Methods and compositions for templated assembly of nucleic acid specific heterocompounds
EP2888227A4 (en) Novel prodrugs and methods of use thereof
SG11201507104WA (en) Novel nucleic acid molecules
IL241290A0 (en) Sovaprevir polymorphs and methods of manufacture thereof
IL246258A0 (en) Synthesis of ent-progesterone and intermediates thereof
EP2968396A4 (en) Locked nucleic acid inhibitor of mir-145 and uses thereof
EP2925341A4 (en) Peptide compounds and methods of production and use thereof
EP2844767A4 (en) Nucleic acid sequencing systems and methods
GB201306093D0 (en) Quantitative detection of specific nucleic acid sequences
EP2865759A4 (en) Nucleic acid complex and nucleic acid-polysaccharide complex

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20150903

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

RIC1 Information provided on ipc code assigned before grant

Ipc: C07H 21/04 20060101ALI20151111BHEP

Ipc: C12Q 1/68 20060101ALI20151111BHEP

Ipc: C12P 19/34 20060101AFI20151111BHEP

REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1211628

Country of ref document: HK

A4 Supplementary search report drawn up and despatched

Effective date: 20161010

RIC1 Information provided on ipc code assigned before grant

Ipc: C12Q 1/68 20060101ALI20161004BHEP

Ipc: C12P 19/34 20060101AFI20161004BHEP

Ipc: C07H 21/04 20060101ALI20161004BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20161125

DAX Request for extension of the european patent (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20180731

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1211628

Country of ref document: HK