EP2830620A4 - 4 aminopyridine as a therapeutic agent for spinal muscular atrophy - Google Patents

4 aminopyridine as a therapeutic agent for spinal muscular atrophy

Info

Publication number
EP2830620A4
EP2830620A4 EP13769101.0A EP13769101A EP2830620A4 EP 2830620 A4 EP2830620 A4 EP 2830620A4 EP 13769101 A EP13769101 A EP 13769101A EP 2830620 A4 EP2830620 A4 EP 2830620A4
Authority
EP
European Patent Office
Prior art keywords
aminopyridine
therapeutic agent
muscular atrophy
spinal muscular
spinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13769101.0A
Other languages
German (de)
French (fr)
Other versions
EP2830620A1 (en
Inventor
Brian Mccabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
Original Assignee
Columbia University in the City of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York
Publication of EP2830620A1 publication Critical patent/EP2830620A1/en
Publication of EP2830620A4 publication Critical patent/EP2830620A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
EP13769101.0A 2012-03-26 2013-03-26 4 aminopyridine as a therapeutic agent for spinal muscular atrophy Withdrawn EP2830620A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261615466P 2012-03-26 2012-03-26
PCT/US2013/033952 WO2013148740A1 (en) 2012-03-26 2013-03-26 4–aminopyridine as a therapeutic agent for spinal muscular atrophy

Publications (2)

Publication Number Publication Date
EP2830620A1 EP2830620A1 (en) 2015-02-04
EP2830620A4 true EP2830620A4 (en) 2015-12-09

Family

ID=49261189

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13769101.0A Withdrawn EP2830620A4 (en) 2012-03-26 2013-03-26 4 aminopyridine as a therapeutic agent for spinal muscular atrophy

Country Status (4)

Country Link
EP (1) EP2830620A4 (en)
JP (1) JP2015512409A (en)
CN (1) CN104334174A (en)
WO (1) WO2013148740A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3029113A1 (en) 2014-12-02 2016-06-03 Univ Paris-Sud COMPOUNDS FOR THE TREATMENT OF MITOCHONDRIAL DISEASES
CN106511293B (en) * 2015-09-11 2020-08-04 法德生技药品股份有限公司 Sustained-release oral preparation containing dapipridine and use thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010048273A2 (en) * 2008-10-21 2010-04-29 President And Fellows Of Harvard College Methods and compounds for treatment of neurodegenerative disorders
WO2012050884A2 (en) * 2010-09-28 2012-04-19 President And Fellows Of Harvard College Cardiac glycosides are potent inhibitors of interferon-beta gene expression

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952357A (en) * 1993-12-23 1999-09-14 Cornell Research Foundation, Inc. Treating diseases of the anterior horn cells
EP1328261A2 (en) * 2000-04-12 2003-07-23 Minerva Biotechnologies Corporation Treatment of neurodegenerative disease
JP2013515734A (en) * 2009-12-23 2013-05-09 エラン ファーマシューティカルズ，インコーポレイテッド Pteridinone as an inhibitor of polo-like kinases
KR20120125357A (en) * 2010-02-10 2012-11-14 노파르티스 아게 Methods and compounds for muscle growth
JP5549260B2 (en) * 2010-02-16 2014-07-16 富士通株式会社 Storage system and data writing method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010048273A2 (en) * 2008-10-21 2010-04-29 President And Fellows Of Harvard College Methods and compounds for treatment of neurodegenerative disorders
WO2012050884A2 (en) * 2010-09-28 2012-04-19 President And Fellows Of Harvard College Cardiac glycosides are potent inhibitors of interferon-beta gene expression

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2013148740A1 *

Also Published As

Publication number Publication date
CN104334174A (en) 2015-02-04
JP2015512409A (en) 2015-04-27
WO2013148740A1 (en) 2013-10-03
EP2830620A1 (en) 2015-02-04

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20141027

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AX Request for extension of the european patent

Extension state: BA ME

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 21/00 20060101ALI20150714BHEP

Ipc: A61K 31/4409 20060101AFI20150714BHEP

RA4 Supplementary search report drawn up and despatched (corrected)

Effective date: 20151110

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/4409 20060101AFI20151104BHEP

Ipc: A61P 21/00 20060101ALI20151104BHEP

STAA Information on the status of an ep patent application or granted ep patent

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Effective date: 20160608