EP2830620A4 - 4 aminopyridine as a therapeutic agent for spinal muscular atrophy - Google Patents
4 aminopyridine as a therapeutic agent for spinal muscular atrophyInfo
- Publication number
- EP2830620A4 EP2830620A4 EP13769101.0A EP13769101A EP2830620A4 EP 2830620 A4 EP2830620 A4 EP 2830620A4 EP 13769101 A EP13769101 A EP 13769101A EP 2830620 A4 EP2830620 A4 EP 2830620A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- aminopyridine
- therapeutic agent
- muscular atrophy
- spinal muscular
- spinal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- NUKYPUAOHBNCPY-UHFFFAOYSA-N 4-aminopyridine Chemical compound NC1=CC=NC=C1 NUKYPUAOHBNCPY-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229960004979 fampridine Drugs 0.000 title 1
- 208000002320 spinal muscular atrophy Diseases 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261615466P | 2012-03-26 | 2012-03-26 | |
PCT/US2013/033952 WO2013148740A1 (en) | 2012-03-26 | 2013-03-26 | 4–aminopyridine as a therapeutic agent for spinal muscular atrophy |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2830620A1 EP2830620A1 (en) | 2015-02-04 |
EP2830620A4 true EP2830620A4 (en) | 2015-12-09 |
Family
ID=49261189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13769101.0A Withdrawn EP2830620A4 (en) | 2012-03-26 | 2013-03-26 | 4 aminopyridine as a therapeutic agent for spinal muscular atrophy |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2830620A4 (en) |
JP (1) | JP2015512409A (en) |
CN (1) | CN104334174A (en) |
WO (1) | WO2013148740A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3029113A1 (en) | 2014-12-02 | 2016-06-03 | Univ Paris-Sud | COMPOUNDS FOR THE TREATMENT OF MITOCHONDRIAL DISEASES |
US10172842B2 (en) | 2015-09-11 | 2019-01-08 | PharmaDax Inc. | Sustained release oral dosage form containing dalfampridine |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010048273A2 (en) * | 2008-10-21 | 2010-04-29 | President And Fellows Of Harvard College | Methods and compounds for treatment of neurodegenerative disorders |
WO2012050884A2 (en) * | 2010-09-28 | 2012-04-19 | President And Fellows Of Harvard College | Cardiac glycosides are potent inhibitors of interferon-beta gene expression |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5952357A (en) * | 1993-12-23 | 1999-09-14 | Cornell Research Foundation, Inc. | Treating diseases of the anterior horn cells |
EP1328261A2 (en) * | 2000-04-12 | 2003-07-23 | Minerva Biotechnologies Corporation | Treatment of neurodegenerative disease |
US8541418B2 (en) * | 2009-12-23 | 2013-09-24 | Elan Pharmaceutical, Inc. | Inhibitors of polo-like kinase |
MX2012009318A (en) * | 2010-02-10 | 2012-09-07 | Novartis Ag | Methods and compounds for muscle growth. |
JP5549260B2 (en) * | 2010-02-16 | 2014-07-16 | 富士通株式会社 | Storage system and data writing method |
-
2013
- 2013-03-26 WO PCT/US2013/033952 patent/WO2013148740A1/en active Application Filing
- 2013-03-26 EP EP13769101.0A patent/EP2830620A4/en not_active Withdrawn
- 2013-03-26 CN CN201380027537.0A patent/CN104334174A/en active Pending
- 2013-03-26 JP JP2015503478A patent/JP2015512409A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010048273A2 (en) * | 2008-10-21 | 2010-04-29 | President And Fellows Of Harvard College | Methods and compounds for treatment of neurodegenerative disorders |
WO2012050884A2 (en) * | 2010-09-28 | 2012-04-19 | President And Fellows Of Harvard College | Cardiac glycosides are potent inhibitors of interferon-beta gene expression |
Non-Patent Citations (1)
Title |
---|
See also references of WO2013148740A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2013148740A1 (en) | 2013-10-03 |
EP2830620A1 (en) | 2015-02-04 |
JP2015512409A (en) | 2015-04-27 |
CN104334174A (en) | 2015-02-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20141027 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAX | Request for extension of the european patent (deleted) | ||
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 21/00 20060101ALI20150714BHEP Ipc: A61K 31/4409 20060101AFI20150714BHEP |
|
RA4 | Supplementary search report drawn up and despatched (corrected) |
Effective date: 20151110 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/4409 20060101AFI20151104BHEP Ipc: A61P 21/00 20060101ALI20151104BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20160608 |