EP2707007A4 - Antifungal compositions for the treatment of skin and nails - Google Patents

Antifungal compositions for the treatment of skin and nails

Info

Publication number
EP2707007A4
EP2707007A4 EP12781719.5A EP12781719A EP2707007A4 EP 2707007 A4 EP2707007 A4 EP 2707007A4 EP 12781719 A EP12781719 A EP 12781719A EP 2707007 A4 EP2707007 A4 EP 2707007A4
Authority
EP
European Patent Office
Prior art keywords
nails
skin
treatment
antifungal compositions
antifungal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP12781719.5A
Other languages
German (de)
French (fr)
Other versions
EP2707007A1 (en
EP2707007B1 (en
Inventor
Joseph Capriotti
Kara Capriotti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Veloce Biopharma LLC
Original Assignee
Alc Therapeutics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alc Therapeutics LLC filed Critical Alc Therapeutics LLC
Priority to EP18153685.5A priority Critical patent/EP3348272B1/en
Publication of EP2707007A1 publication Critical patent/EP2707007A1/en
Publication of EP2707007A4 publication Critical patent/EP2707007A4/en
Application granted granted Critical
Publication of EP2707007B1 publication Critical patent/EP2707007B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP12781719.5A 2011-05-11 2012-05-08 Antifungal compositions for the treatment of nails Not-in-force EP2707007B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP18153685.5A EP3348272B1 (en) 2011-05-11 2012-05-08 Composition for use in the treatment of paronychia

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161518690P 2011-05-11 2011-05-11
US201161518689P 2011-05-11 2011-05-11
US201161518709P 2011-05-11 2011-05-11
US201161457699P 2011-05-16 2011-05-16
US201161627148P 2011-09-19 2011-09-19
US201261600268P 2012-02-17 2012-02-17
PCT/US2012/036942 WO2012154740A1 (en) 2011-05-11 2012-05-08 Antifungal compositions for the treatment of skin and nails

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP18153685.5A Division EP3348272B1 (en) 2011-05-11 2012-05-08 Composition for use in the treatment of paronychia
EP18153685.5A Division-Into EP3348272B1 (en) 2011-05-11 2012-05-08 Composition for use in the treatment of paronychia

Publications (3)

Publication Number Publication Date
EP2707007A1 EP2707007A1 (en) 2014-03-19
EP2707007A4 true EP2707007A4 (en) 2014-10-15
EP2707007B1 EP2707007B1 (en) 2018-03-07

Family

ID=47139601

Family Applications (2)

Application Number Title Priority Date Filing Date
EP18153685.5A Active EP3348272B1 (en) 2011-05-11 2012-05-08 Composition for use in the treatment of paronychia
EP12781719.5A Not-in-force EP2707007B1 (en) 2011-05-11 2012-05-08 Antifungal compositions for the treatment of nails

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP18153685.5A Active EP3348272B1 (en) 2011-05-11 2012-05-08 Composition for use in the treatment of paronychia

Country Status (7)

Country Link
US (2) US9408867B2 (en)
EP (2) EP3348272B1 (en)
JP (6) JP6077527B2 (en)
CA (1) CA2835684C (en)
ES (2) ES2665986T3 (en)
MX (1) MX345458B (en)
WO (1) WO2012154740A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2835684C (en) 2011-05-11 2019-10-08 Alc Therapeutics, Llc Antifungal compositions for the treatment of skin and nails
JP6122035B2 (en) * 2012-02-17 2017-04-26 ヴェローチェ・バイオファーマ・エルエルシー Antifungal composition for the treatment of skin and nails
US20140271529A1 (en) * 2013-03-14 2014-09-18 Alc Therapeutics, Llc Antifungal compositions for the treatment of secondary skin and nail infections
CA2973725A1 (en) 2015-01-20 2016-07-28 Veloce Biopharma Llc Novel iodophor composition and methods of use
EP3258908A4 (en) * 2015-02-20 2018-08-22 Pedicis Research LLC Compositions and methods for treatment of skin infections
CA2990627A1 (en) 2015-06-22 2016-12-29 Infection Containment Company, LLC Topical antiseptic system
US20180200289A1 (en) * 2015-07-02 2018-07-19 Veloce Biopharma, Llc Novel ophthalmic composition and methods of use
US9770466B2 (en) 2015-07-02 2017-09-26 Veloce Biopharma, Llc Ophthalmic composition and methods of use
JP6255134B1 (en) * 2016-11-02 2017-12-27 ヴェローチェ・バイオファーマ・エルエルシー Compositions and methods for the treatment of otitis
US10993890B2 (en) * 2018-03-15 2021-05-04 Pelli Skin Co., Llc Antifungal solution and foot wipe

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6264927B1 (en) * 1998-08-27 2001-07-24 Elmer P. Monahan Topical solution and method for the treatment of nail fungus

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BE615889A (en) * 1952-04-15 1900-01-01
US3551554A (en) * 1968-08-16 1970-12-29 Crown Zellerbach Corp Enhancing tissue penetration of physiologically active agents with dmso
WO1985005036A1 (en) * 1984-04-30 1985-11-21 The Trustees Of Columbia University In The City Of Topical treatment of diabetes with insulin and penetrant enhancer applied to the skin and covered by a patch
CA1236029A (en) 1984-05-14 1988-05-03 Edmund Sandborn Pharmaceutical solutions comprising dimethyl sulfoxide
IL77224A (en) * 1984-12-12 1989-09-10 Euro Celtique Sa Antibacterial cream
JPS6216419A (en) * 1985-07-15 1987-01-24 Hirokazu Takaoka External drug for athlete's foot
GB2275191B (en) 1993-02-10 1996-11-27 Donald John Dear Use of antifungal compounds in the treatment of skin disorders
GB9426088D0 (en) * 1994-12-23 1995-02-22 Geco As Data compression for uncorrelated vibroseis traces
US5993790A (en) * 1997-08-04 1999-11-30 Pedinol Pharmacal Inc. Nail evulsion compositions and method for evulsing nails and treating nail and nail bed infections
US6159977A (en) 1998-11-16 2000-12-12 Astan, Inc. Therapeutic anti-fungal nail preparation
US7074392B1 (en) * 2000-03-27 2006-07-11 Taro Pharmaceutical Industries Limited Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections
US20030049320A1 (en) * 2000-12-18 2003-03-13 Wockhardt Limited Novel in-situ forming controlled release microcarrier delivery system
US6921529B2 (en) * 2002-07-29 2005-07-26 Joseph C. Maley Treatment modality and method for fungal nail infection
US20070292355A1 (en) * 2002-10-25 2007-12-20 Foamix Ltd. Anti-infection augmentation foamable compositions and kit and uses thereof
US20070292359A1 (en) * 2002-10-25 2007-12-20 Foamix Ltd. Polypropylene glycol foamable vehicle and pharmaceutical compositions thereof
PL2106805T3 (en) * 2003-03-21 2011-10-31 Nexmed Holdings Inc Antifungal nail coat and method of use
ATE371436T1 (en) * 2003-05-19 2007-09-15 Euro Celtique Sa DRY LIPOSOMAL PVP-IODINE PREPARATIONS
US20040241114A1 (en) * 2003-05-30 2004-12-02 Gupta Shyam K. Hair Care and Nail Care Compositions Based on Ion-Pair Delivery System for Gender and Ethnic Selective Applications
JP2005097279A (en) * 2003-08-28 2005-04-14 Jcs:Kk Conchitis-treating agent and external auditory meatus-cleaning liquid
US20060165747A1 (en) * 2005-01-24 2006-07-27 David Rolf Antifungal composition, method and kit for topically treating onychomycosis
GB0511499D0 (en) * 2005-06-06 2005-07-13 Medpharm Ltd Topical ungual formulations
US8512724B2 (en) * 2005-06-10 2013-08-20 The Board Of Regents Of The University Of Texas System Antiseptic compositions
US20080319092A1 (en) * 2005-08-05 2008-12-25 Nuvo Research Inc. Transdermal Drug Delivery Formulation
KR20090029139A (en) * 2007-09-17 2009-03-20 김부례 The ointment operating upon athlete's foots with a mechanism of mollification and penetration and suction
CN100531706C (en) * 2007-10-29 2009-08-26 广东庆发药业有限公司 Antimicrobial disinfection hand cleanser and preparation method thereof
US20090263345A1 (en) * 2008-01-28 2009-10-22 Foresight Biotherapeutics, Inc. Otic compositions for the treatment of infections of the internal and external ear in mammals
CN101693038B (en) * 2008-10-17 2012-06-20 吴霜 Pharmaceutical composition for treating skin (A) disease
CA2835684C (en) 2011-05-11 2019-10-08 Alc Therapeutics, Llc Antifungal compositions for the treatment of skin and nails
US20140271529A1 (en) * 2013-03-14 2014-09-18 Alc Therapeutics, Llc Antifungal compositions for the treatment of secondary skin and nail infections

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6264927B1 (en) * 1998-08-27 2001-07-24 Elmer P. Monahan Topical solution and method for the treatment of nail fungus

Also Published As

Publication number Publication date
JP6360267B2 (en) 2018-07-18
JP2017222698A (en) 2017-12-21
EP3348272A1 (en) 2018-07-18
JP6236141B2 (en) 2017-11-22
JP2018109041A (en) 2018-07-12
EP3348272B1 (en) 2020-06-24
EP2707007A1 (en) 2014-03-19
WO2012154740A1 (en) 2012-11-15
US20140205559A1 (en) 2014-07-24
MX345458B (en) 2017-02-01
EP2707007B1 (en) 2018-03-07
JP6077527B2 (en) 2017-02-08
ES2665986T3 (en) 2018-04-30
JP2018048159A (en) 2018-03-29
US9408867B2 (en) 2016-08-09
MX2013013082A (en) 2014-04-25
US20170000820A1 (en) 2017-01-05
JP6273065B1 (en) 2018-01-31
CA2835684A1 (en) 2012-11-15
JP6307203B1 (en) 2018-04-04
JP2018065854A (en) 2018-04-26
ES2817835T3 (en) 2021-04-08
JP6239183B1 (en) 2017-11-29
CA2835684C (en) 2019-10-08
JP2017078088A (en) 2017-04-27
JP2014518865A (en) 2014-08-07

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