EP2622077A4 - Method for converting and producing carbonate minerals from carbon dioxide using recombinant biocatalyst - Google Patents

Method for converting and producing carbonate minerals from carbon dioxide using recombinant biocatalyst

Info

Publication number
EP2622077A4
EP2622077A4 EP12804123.3A EP12804123A EP2622077A4 EP 2622077 A4 EP2622077 A4 EP 2622077A4 EP 12804123 A EP12804123 A EP 12804123A EP 2622077 A4 EP2622077 A4 EP 2622077A4
Authority
EP
European Patent Office
Prior art keywords
converting
carbon dioxide
carbonate minerals
producing carbonate
recombinant biocatalyst
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP12804123.3A
Other languages
German (de)
French (fr)
Other versions
EP2622077A1 (en
EP2622077B1 (en
Inventor
Hyung Joon Cha
Im Gyu Kim
Dong Gyun Kang
Byung Hoon Jo
Jeong Hyun Seo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Academy Industry Foundation of POSTECH
Original Assignee
Academy Industry Foundation of POSTECH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Academy Industry Foundation of POSTECH filed Critical Academy Industry Foundation of POSTECH
Publication of EP2622077A1 publication Critical patent/EP2622077A1/en
Publication of EP2622077A4 publication Critical patent/EP2622077A4/en
Application granted granted Critical
Publication of EP2622077B1 publication Critical patent/EP2622077B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P3/00Preparation of elements or inorganic compounds except carbon dioxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP12804123.3A 2011-06-29 2012-04-13 Method for converting and producing carbonate minerals from carbon dioxide using recombinant biocatalyst Not-in-force EP2622077B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20110063729 2011-06-29
KR1020120023429A KR101424605B1 (en) 2011-06-29 2012-03-07 Method for converting and producing carbonate minerals from carbon dioxide using recombinant biocatalyst
PCT/KR2012/002816 WO2013002481A1 (en) 2011-06-29 2012-04-13 Method for converting and producing carbonate minerals from carbon dioxide using recombinant biocatalyst

Publications (3)

Publication Number Publication Date
EP2622077A1 EP2622077A1 (en) 2013-08-07
EP2622077A4 true EP2622077A4 (en) 2014-08-20
EP2622077B1 EP2622077B1 (en) 2017-10-25

Family

ID=47835398

Family Applications (1)

Application Number Title Priority Date Filing Date
EP12804123.3A Not-in-force EP2622077B1 (en) 2011-06-29 2012-04-13 Method for converting and producing carbonate minerals from carbon dioxide using recombinant biocatalyst

Country Status (6)

Country Link
US (1) US9051586B2 (en)
EP (1) EP2622077B1 (en)
JP (1) JP2013541954A (en)
KR (1) KR101424605B1 (en)
AU (1) AU2012276539B2 (en)
WO (1) WO2013002481A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015056858A1 (en) * 2013-10-17 2015-04-23 포항공과대학교 산학협력단 Carbonic anhydrase having high-temperature stability and carbon dioxide collector comprising same
KR101576031B1 (en) 2013-12-03 2015-12-09 연세대학교 산학협력단 BIO MIMIC ZINC-HISTIDINE SELF-ASSEMBLY COMPLEX and A METHOD FOR PREPARING THE SAME, AND A METHOD FOR REDUCING CARBON DIOXIDE USING SAID COMPLEX
KR101634794B1 (en) * 2014-07-07 2016-06-29 한국에너지기술연구원 Complex catalysts comprising enzyme and metal, membrane-electrode assembly, electrochemical cell and method for preparing formic acid from carbon dioxide thereof
CN104313055B (en) * 2014-09-25 2017-03-22 南京工业大学 Method for preparing strontium carbonate by microorganisms
WO2017078422A1 (en) * 2015-11-03 2017-05-11 한국과학기술원 Transformant having increased carbonic anhydration activity, using neisseria gonorrhoeae-derived carbonic anhydrase
CN109651513B (en) * 2018-10-18 2021-08-31 上海交通大学 Recombinant fusion protein for specifically recognizing tumor cells and application thereof
US11471816B2 (en) 2019-03-11 2022-10-18 Karim Salehpoor Pollutant capturer and mobilizer
US20200354726A1 (en) * 2019-03-22 2020-11-12 Biocompanion Inc. Method of mass-producing carbonic anhydrase in plant
CN113874500A (en) * 2019-03-26 2021-12-31 塞彭公司 For improving CO2Captured carbonic anhydrase variants
KR102599847B1 (en) * 2021-04-01 2023-11-07 경상국립대학교산학협력단 Method for immobilization of whole-cell catalyst in biomimetics silica for increased thermal stability

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100597808B1 (en) 2004-04-12 2006-07-06 주식회사 케이티프리텔 Method and apparatus for providing service of interrupting spam short message
US20110045557A1 (en) * 2007-07-27 2011-02-24 Mohammed Ataai Novel Fusion Carbonic Anhydrase/Cellulose Binding Polypeptide Encoded by a Novel Hybrid Gene, and Method of Creating and Using the Same
WO2009021548A1 (en) * 2007-08-10 2009-02-19 Wacker Chemie Ag Expression of full length igg and secretion into the culture medium of prokaryotic cells
GB0821537D0 (en) * 2008-11-25 2008-12-31 Union Life Sciences Ltd Therapeutic target
CA2749121A1 (en) * 2009-01-09 2010-07-15 Codexis, Inc. Carbonic anhydrase polypeptides and uses thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
FAVRE N ET AL: "Biocatalytic capture of CO2 with carbonic anhydrase and its transformation to solid carbonate", JOURNAL OF MOLECULAR CATALYSIS. B, ENZYMATIC, ELSEVIER, AMSTERDAM, NL, vol. 60, no. 3-4, 1 October 2009 (2009-10-01), pages 163 - 170, XP026439361, ISSN: 1381-1177, [retrieved on 20090506] *
IM GYU KIM ET AL: "Biomineralization-based conversion of carbon dioxide to calcium carbonate using recombinant carbonic anhydrase", CHEMOSPHERE, vol. 87, no. 10, 1 June 2012 (2012-06-01), pages 1091 - 1096, XP055127599, ISSN: 0045-6535, DOI: 10.1016/j.chemosphere.2012.02.003 *
PARISSA MIRJAFARI ET AL: "Investigating the Application of Enzyme Carbonic Anhydrase for CO 2 Sequestration Purposes", INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, vol. 46, no. 3, 1 January 2007 (2007-01-01), pages 921 - 926, XP055128075, ISSN: 0888-5885, DOI: 10.1021/ie060287u *
See also references of WO2013002481A1 *

Also Published As

Publication number Publication date
AU2012276539A1 (en) 2013-03-14
AU2012276539B2 (en) 2015-02-05
KR101424605B1 (en) 2014-08-04
US9051586B2 (en) 2015-06-09
KR20130002922A (en) 2013-01-08
EP2622077A1 (en) 2013-08-07
EP2622077B1 (en) 2017-10-25
WO2013002481A1 (en) 2013-01-03
JP2013541954A (en) 2013-11-21
US20140113339A1 (en) 2014-04-24

Similar Documents

Publication Publication Date Title
EP2622077A4 (en) Method for converting and producing carbonate minerals from carbon dioxide using recombinant biocatalyst
PL2563495T3 (en) Method for carbon dioxide capture
IL233210A0 (en) Process and system for conversion carbon dioxide into carbon monoxide
EP2838839A4 (en) Method for producing solid carbon by reducing carbon dioxide
EP2737938A4 (en) Carbon dioxide separation member, method for producing same, and carbon dioxide separation module
EP2650258A4 (en) Gasification method for reducing emission of carbon dioxide
HUE051809T2 (en) Method for producing methane from carbon dioxide
HK1199439A1 (en) Carbon material and method for producing same
EP2554241A4 (en) Carbon dioxide separation unit and carbon dioxide separation method
PL2544998T3 (en) System and method for generating a carbon dioxide stream
EP2520353A4 (en) Carbon dioxide capture system and method
LU91517B1 (en) Method for producing pulverized coal
ZA201302899B (en) Serializing document editing commands
EP2540697A4 (en) Method for producing diaryl carbonate
ZA201309573B (en) Carbon dioxide production
ZA201208063B (en) Process for the capture of carbon dioxide
EP2639295A4 (en) Coryneform bacterium transformant and method for producing phenol using same
EP2772297A4 (en) Carbon dioxide recovery method and recovery device
EP2740527A4 (en) Method and device for recovering carbon dioxide
EP2639072A4 (en) Inkjet head and method for producing inkjet head
EP2639306A4 (en) Coryneform bacterium transformant and method for producing phenol using same
EP2520351A4 (en) Absorbing solution and recovery method for carbon dioxide
PL2567043T3 (en) Method for producing panels with bevelled edges
GB0910043D0 (en) Process for reducing carbon dioxide emissions
SG11201500287PA (en) Method for producing linear and/or cyclic carbonate esters

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20130307

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Ref document number: 602012039001

Country of ref document: DE

Free format text: PREVIOUS MAIN CLASS: C12N0015600000

Ipc: C12N0009880000

A4 Supplementary search report drawn up and despatched

Effective date: 20140721

RIC1 Information provided on ipc code assigned before grant

Ipc: C12N 9/88 20060101AFI20140715BHEP

Ipc: C12P 3/00 20060101ALI20140715BHEP

DAX Request for extension of the european patent (deleted)
17Q First examination report despatched

Effective date: 20151023

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20170616

RIN1 Information on inventor provided before grant (corrected)

Inventor name: CHA, HYUNG JOON

Inventor name: KANG, DONG GYUN

Inventor name: SEO, JEONG HYUN

Inventor name: JO, BYUNG HOON

Inventor name: KIM, IM GYU

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 939971

Country of ref document: AT

Kind code of ref document: T

Effective date: 20171115

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602012039001

Country of ref document: DE

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20171025

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 939971

Country of ref document: AT

Kind code of ref document: T

Effective date: 20171025

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20180125

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20180125

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20180225

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20180126

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602012039001

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20180418

Year of fee payment: 7

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20180726

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20180430

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20180413

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180413

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180413

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180430

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180430

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180430

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180430

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180413

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 602012039001

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180413

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20191101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20120413

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20171025

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171025