EP2443259A4 - BIOMARKERS ASSOCIATED WITH AUTISM AND USES THEREOF - Google Patents

BIOMARKERS ASSOCIATED WITH AUTISM AND USES THEREOF

Info

Publication number
EP2443259A4
EP2443259A4 EP10789901A EP10789901A EP2443259A4 EP 2443259 A4 EP2443259 A4 EP 2443259A4 EP 10789901 A EP10789901 A EP 10789901A EP 10789901 A EP10789901 A EP 10789901A EP 2443259 A4 EP2443259 A4 EP 2443259A4
Authority
EP
European Patent Office
Prior art keywords
autism
biomarkers associated
biomarkers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10789901A
Other languages
German (de)
French (fr)
Other versions
EP2443259A1 (en
Inventor
W Ian Lipkin
Mady Hornig
Brent L Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University
Original Assignee
Columbia University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia University filed Critical Columbia University
Publication of EP2443259A1 publication Critical patent/EP2443259A1/en
Publication of EP2443259A4 publication Critical patent/EP2443259A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP10789901A 2009-06-16 2010-05-10 BIOMARKERS ASSOCIATED WITH AUTISM AND USES THEREOF Withdrawn EP2443259A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18760609P 2009-06-16 2009-06-16
PCT/US2010/034254 WO2010147714A1 (en) 2009-06-16 2010-05-10 Autism-associated biomarkers and uses thereof

Publications (2)

Publication Number Publication Date
EP2443259A1 EP2443259A1 (en) 2012-04-25
EP2443259A4 true EP2443259A4 (en) 2012-10-10

Family

ID=43356678

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10789901A Withdrawn EP2443259A4 (en) 2009-06-16 2010-05-10 BIOMARKERS ASSOCIATED WITH AUTISM AND USES THEREOF

Country Status (2)

Country Link
EP (1) EP2443259A4 (en)
WO (1) WO2010147714A1 (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9707207B2 (en) * 2010-05-26 2017-07-18 The United States Of America As Represented By The Department Of Veterans Affairs Method for diagnosing, preventing, and treating neurological diseases
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
EP3323897A1 (en) * 2011-10-03 2018-05-23 Celmatix, Inc. Methods and devices for assessing risk to a putative offspring of developing a condition
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
US10039777B2 (en) * 2012-03-20 2018-08-07 Neuro-Lm Sas Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders
EA201590175A1 (en) * 2012-07-26 2015-06-30 Дзе Реджентс Оф Дзе Юниверсити Оф Калифорния SCREENING, DIAGNOSTICS AND FORECASTING OF AUTISM AND OTHER DEVELOPMENTAL DISABILITIES
US10162800B2 (en) 2012-10-17 2018-12-25 Celmatix Inc. Systems and methods for determining the probability of a pregnancy at a selected point in time
US9177098B2 (en) 2012-10-17 2015-11-03 Celmatix Inc. Systems and methods for determining the probability of a pregnancy at a selected point in time
US9836577B2 (en) 2012-12-14 2017-12-05 Celmatix, Inc. Methods and devices for assessing risk of female infertility
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
WO2016011377A1 (en) 2014-07-17 2016-01-21 Celmatix Inc. Methods and systems for assessing infertility and related pathologies
DK3193901T3 (en) 2014-12-23 2018-05-28 4D Pharma Res Ltd PIRIN POLYPEPTIDE AND IMMUNMODULATION
PE20171138A1 (en) 2014-12-23 2017-08-09 4D Pharma Res Ltd IMMUNE MODULATION
EP3662917A1 (en) 2015-06-15 2020-06-10 4D Pharma Research Limited Compositions comprising bacterial strains
LT3360559T (en) 2015-06-15 2019-12-27 4D Pharma Research Limited Compositions comprising bacterial strains
MA41060B1 (en) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprising bacterial strains
MA41010B1 (en) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprising bacterial strains
PE20180243A1 (en) 2015-06-15 2018-01-31 4D Pharma Res Ltd COMPOSITIONS INCLUDING BACTERIAL STRAINS
MA41013A (en) 2015-11-20 2017-08-30 4D Pharma Res Ltd COMPOSITIONS CONTAINING BACTERIAL STRAINS
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
MX373290B (en) 2016-03-04 2020-06-18 4D Pharma Plc COMPOSITIONS INCLUDING BACTERIAL STRAINS.
US11946927B2 (en) 2016-03-14 2024-04-02 Musidora Biotechnology Llc Process and system for identifying individuals having a high risk of inflammatory bowel disease and a method of treatment
US10295527B2 (en) 2016-03-14 2019-05-21 Bruce Yacyshyn Process and system for predicting responders and non-responders to mesalamine treatment of ulcerative colitis
TWI802545B (en) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 Compositions comprising bacterial strains
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
MA48940A (en) 2017-05-22 2020-04-08 4D Pharma Res Ltd COMPOSITIONS CONTAINING BACTERIAL STRAINS
MA41708A (en) 2017-05-24 2020-04-08 4D Pharma Res Ltd COMPOSITIONS CONTAINING BACTERIAL STRAINS
KR102008451B1 (en) * 2017-05-26 2019-08-07 주식회사 엠디헬스케어 Method for diagnosis of Autism using analysis of bacteria metagenome
JP2020523326A (en) 2017-06-14 2020-08-06 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ Composition comprising a bacterial strain
TWI767013B (en) 2017-06-14 2022-06-11 英商4D製藥研究有限公司 Compositions comprising bacterial strains
PL3638271T3 (en) 2017-06-14 2021-03-22 4D Pharma Research Limited Compositions comprising bacterial strains
WO2019227418A1 (en) * 2018-05-31 2019-12-05 深圳华大生命科学研究院 Composition and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006060414A2 (en) * 2004-12-01 2006-06-08 Kirkman Group, Inc. Compositions and methods for the treatment of autism
US7091182B2 (en) * 1997-05-19 2006-08-15 Repligen Corporation Method for assisting in differential diagnosis and treatment of autistic syndromes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040170617A1 (en) * 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
WO2005115478A2 (en) * 2004-05-11 2005-12-08 The Regents Of The University Of California Methods and compositions for autism spectrum disorders
EP1848826A2 (en) * 2005-02-17 2007-10-31 Integragen Human autism susceptibility gene encoding a kinase and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091182B2 (en) * 1997-05-19 2006-08-15 Repligen Corporation Method for assisting in differential diagnosis and treatment of autistic syndromes
WO2006060414A2 (en) * 2004-12-01 2006-06-08 Kirkman Group, Inc. Compositions and methods for the treatment of autism

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HORVATH K ET AL: "Gastrointestinal abnormalities in children with autistic disorder", JOURNAL OF PEDIATRICS, vol. 135, no. 5, 1 November 1999 (1999-11-01), MOSBY-YEAR BOOK, ST. LOUIS, MO, US, pages 559 - 563, XP027314235, ISSN: 0022-3476, [retrieved on 19991101] *
See also references of WO2010147714A1 *
WILLIAMS B T ET AL.: "Impaired carbohydrate digestion and transport ands mucosal dysbiosis in the intestines of children with autism and gastrointestinal disturbances", PLOS ONE, vol. 6, no. 9, E24585, September 2011 (2011-09-01), pages 1 - 21, XP002682053 *

Also Published As

Publication number Publication date
EP2443259A1 (en) 2012-04-25
WO2010147714A1 (en) 2010-12-23

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