EP2389189A4 - Method for the prevention and treatment of diastolic dysfunction employing an apolipoproteina1 (apoa1) mimetic peptide/phospholipid complex - Google Patents
Method for the prevention and treatment of diastolic dysfunction employing an apolipoproteina1 (apoa1) mimetic peptide/phospholipid complexInfo
- Publication number
- EP2389189A4 EP2389189A4 EP10733186A EP10733186A EP2389189A4 EP 2389189 A4 EP2389189 A4 EP 2389189A4 EP 10733186 A EP10733186 A EP 10733186A EP 10733186 A EP10733186 A EP 10733186A EP 2389189 A4 EP2389189 A4 EP 2389189A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- apoa1
- prevention
- treatment
- diastolic dysfunction
- mimetic peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Marine Sciences & Fisheries (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20205109P | 2009-01-23 | 2009-01-23 | |
US20219109P | 2009-02-05 | 2009-02-05 | |
PCT/CA2010/000108 WO2010083611A1 (en) | 2009-01-23 | 2010-01-25 | Method for the prevention and treatment of diastolic dysfunction employing an apolipoproteina1 (apoa1) mimetic peptide/phospholipid complex |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2389189A1 EP2389189A1 (en) | 2011-11-30 |
EP2389189A4 true EP2389189A4 (en) | 2012-12-19 |
Family
ID=42355467
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10733186A Withdrawn EP2389189A4 (en) | 2009-01-23 | 2010-01-25 | Method for the prevention and treatment of diastolic dysfunction employing an apolipoproteina1 (apoa1) mimetic peptide/phospholipid complex |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2389189A4 (en) |
CA (1) | CA2788223A1 (en) |
WO (1) | WO2010083611A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2982157A1 (en) | 2009-02-16 | 2010-08-19 | Cerenis Therapeutics Holding Sa | Apolipoprotein a-i mimics |
EP2598158A4 (en) * | 2010-07-28 | 2014-03-12 | Inst Cardiologie Montreal | Pharmaceutical compositions for the treatment of left ventricular diastolic dysfunction comprising an apolipoprotein peptide/phospholipid complex |
CA2807448A1 (en) | 2010-08-30 | 2012-03-08 | F. Hoffmann-La Roche Ag | Tetranectin-apolipoprotein a-i, lipid particles containing it and its use |
KR20140054115A (en) | 2011-08-25 | 2014-05-08 | 에프. 호프만-라 로슈 아게 | Shortened tetranectin-apolipoprotein a-i fusion protein, a lipid particle containing it, and uses thereof |
US9402975B2 (en) | 2011-08-31 | 2016-08-02 | Becton, Dickinson And Company | Systems and methods to increase rigidity and snag-resistance of catheter tip |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6004925A (en) | 1997-09-29 | 1999-12-21 | J. L. Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
US6287590B1 (en) | 1997-10-02 | 2001-09-11 | Esperion Therapeutics, Inc. | Peptide/lipid complex formation by co-lyophilization |
WO2000059855A1 (en) | 1999-04-01 | 2000-10-12 | Esperion Therapeutics, Inc. | Ether compounds, compositions, and uses thereof |
EP2537526A1 (en) * | 2006-06-01 | 2012-12-26 | Institut de Cardiologie de Montréal | Method and compound for the treatment of valvular stenosis |
-
2010
- 2010-01-25 EP EP10733186A patent/EP2389189A4/en not_active Withdrawn
- 2010-01-25 WO PCT/CA2010/000108 patent/WO2010083611A1/en active Application Filing
- 2010-01-25 CA CA2788223A patent/CA2788223A1/en not_active Abandoned
Non-Patent Citations (8)
Title |
---|
BEYERBACHT H P ET AL: "Aortic valve replacement in patients with aortic valve stenosis improves myocardial metabolism and diastolic function.", June 2001, RADIOLOGY JUN 2001 LNKD- PUBMED:11376247, VOL. 219, NR. 3, PAGE(S) 637 - 643, ISSN: 0033-8419, XP002686474 * |
BUSSEUIL D ET AL: "Regression of aortic valve stenosis by ApoA-I mimetic peptide infusions in rabbits.", June 2008, BRITISH JOURNAL OF PHARMACOLOGY JUN 2008 LNKD- PUBMED:18414386, VOL. 154, NR. 4, PAGE(S) 765 - 773, ISSN: 0007-1188, XP002686476 * |
BUSSEUIL DAVID ET AL: "[A new type of medical treatment could lead to regression of aortic valve stenosis].", August 2008, MÉDECINE SCIENCES : M/S 2008 AUG-SEP LNKD- PUBMED:18789203, VOL. 24, NR. 8-9, PAGE(S) 675 - 676, ISSN: 0767-0974, XP002686475 * |
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; July 2000 (2000-07-01), RISTIC-ANDJELKOV A ET AL: "[Echocardiographic evaluation of left ventricular diastolic function in patients with aortic valve stenosis].", XP002686473, Database accession no. NLM11521465 * |
MANDINOV L ET AL: "Diastolic heart failure", CARDIOVASCULAR RESEARCH, OXFORD UNIVERSITY PRESS, GB, vol. 45, 1 January 2000 (2000-01-01), pages 813 - 825, XP002903841, ISSN: 0008-6363, DOI: 10.1016/S0008-6363(99)00399-5 * |
MARCHESI ET AL: "Apolipoprotein A-IMilano/POPC complex attenuates post-ischemic ventricular dysfunction in the isolated rabbit heart", ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, IE, vol. 197, no. 2, 22 October 2007 (2007-10-22), pages 572 - 578, XP022559364, ISSN: 0021-9150, DOI: 10.1016/J.ATHEROSCLEROSIS.2007.08.028 * |
OLCAY AKSOY ET AL: "Do Bisphosphonates Slow the Progression of Aortic Stenosis?", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER, NEW YORK, NY, US, vol. 59, no. 16, 2 January 2012 (2012-01-02), pages 1452 - 1459, XP028406141, ISSN: 0735-1097, [retrieved on 20120303], DOI: 10.1016/J.JACC.2012.01.024 * |
See also references of WO2010083611A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2788223A1 (en) | 2010-07-29 |
EP2389189A1 (en) | 2011-11-30 |
WO2010083611A1 (en) | 2010-07-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1215182A1 (en) | Herapeutic agents comprising elastin-like peptides | |
HK1208237A1 (en) | Methods for the treatment of gout | |
HK1217293A1 (en) | Methods for the prevention or treatment of heart failure | |
ZA201204625B (en) | Analogues for the treatment or prevention of flavivirus infections | |
GB2464906B (en) | Cryogenic treatment of gas | |
IL218116A (en) | Modified vasoactive intestinal peptides comprising elastin-like peptides | |
IL217503A0 (en) | Benzimidazole analogues for the treatment or prevention of flavivirus infections | |
EP2068768A4 (en) | Method and system for improving diastolic function of the heart | |
EP2097012A4 (en) | Devices and methods for the treatment of heart failure | |
EP2032131A4 (en) | Method of treatment | |
EP2352515A4 (en) | Method for the treatment of hemophilia | |
EP1995254A4 (en) | Method of producing peptide | |
HK1149322A1 (en) | Methods and agents for the diagnosis and treatment of hepatocellular carcinoma | |
HK1155075A1 (en) | Recombinant polyprotein vaccines for the treatment and diagnosis of leishmaniasis | |
GB0610746D0 (en) | Method of treatment | |
HK1167148A1 (en) | Method for the preparation of cyclopeptides | |
EP2717902A4 (en) | Use of modified vasoactive intestinal peptides in the treatment of hypertension | |
EP1996609A4 (en) | Method of preparing glycopeptides | |
EP2389189A4 (en) | Method for the prevention and treatment of diastolic dysfunction employing an apolipoproteina1 (apoa1) mimetic peptide/phospholipid complex | |
HK1134911A1 (en) | Medicament for the treatment of endometriosis | |
EP2411042A4 (en) | Tissue kallikrein for the treatment of pancreatic -cell dysfunction | |
EP2270141A4 (en) | Partial peptide of lacritin | |
EP2262594A4 (en) | Cleaning bullet and method of operating the same | |
ZA201200420B (en) | Method for the purification of protein complexes | |
GB0724953D0 (en) | Methods of peptide modification |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20110823 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 9/00 20060101ALI20121107BHEP Ipc: A61K 38/17 20060101AFI20121107BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20121120 |
|
17Q | First examination report despatched |
Effective date: 20131025 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
INTG | Intention to grant announced |
Effective date: 20141030 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20150310 |