EP2387563A1 - Malate salt of n- (4- { [ 6, 7-bis (methyloxy) quin0lin-4-yl]oxy}phenyl-n' - (4 -fluorophenyl) cyclopropane-1-dicarboxamide, and crystalline forms therof for the treatment of cancer - Google Patents

Malate salt of n- (4- { [ 6, 7-bis (methyloxy) quin0lin-4-yl]oxy}phenyl-n' - (4 -fluorophenyl) cyclopropane-1-dicarboxamide, and crystalline forms therof for the treatment of cancer

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Publication number
EP2387563A1
EP2387563A1 EP10701175A EP10701175A EP2387563A1 EP 2387563 A1 EP2387563 A1 EP 2387563A1 EP 10701175 A EP10701175 A EP 10701175A EP 10701175 A EP10701175 A EP 10701175A EP 2387563 A1 EP2387563 A1 EP 2387563A1
Authority
EP
European Patent Office
Prior art keywords
compound
phenyl
cyclopropane
oxy
methyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10701175A
Other languages
German (de)
French (fr)
Other versions
EP2387563B1 (en
EP2387563B2 (en
Inventor
Adrian St. Clair BROWN
Peter Lamb
William P. Gallagher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exelixis Inc
Original Assignee
Bristol Myers Squibb Co
Exelixis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to US14542109P priority Critical
Application filed by Bristol Myers Squibb Co, Exelixis Inc filed Critical Bristol Myers Squibb Co
Priority to PCT/US2010/021194 priority patent/WO2010083414A1/en
Priority claimed from SI201030193T external-priority patent/SI2387563T2/en
Publication of EP2387563A1 publication Critical patent/EP2387563A1/en
Publication of EP2387563B1 publication Critical patent/EP2387563B1/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41820137&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP2387563(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application granted granted Critical
Publication of EP2387563B2 publication Critical patent/EP2387563B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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