EP2384114A4 - Nutraceuticals containing nitro fatty acids - Google Patents

Nutraceuticals containing nitro fatty acids

Info

Publication number
EP2384114A4
EP2384114A4 EP09837203.0A EP09837203A EP2384114A4 EP 2384114 A4 EP2384114 A4 EP 2384114A4 EP 09837203 A EP09837203 A EP 09837203A EP 2384114 A4 EP2384114 A4 EP 2384114A4
Authority
EP
European Patent Office
Prior art keywords
fatty acids
containing nitro
nitro fatty
nutraceuticals
nutraceuticals containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09837203.0A
Other languages
German (de)
French (fr)
Other versions
EP2384114A1 (en
Inventor
Raymond A Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nitromega Corp
Original Assignee
Nitromega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitromega Corp filed Critical Nitromega Corp
Publication of EP2384114A1 publication Critical patent/EP2384114A1/en
Publication of EP2384114A4 publication Critical patent/EP2384114A4/en
Withdrawn legal-status Critical Current

Links

Classifications

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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
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    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/30Encapsulation of particles, e.g. foodstuff additives
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    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92Oral administration

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Abstract

Activated fatty acids, nutraceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and methods for preparing activated fatty acids are provided herein.
EP09837203.0A 2008-12-31 2009-12-31 Nutraceuticals containing nitro fatty acids Withdrawn EP2384114A4 (en)

Applications Claiming Priority (2)

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US14184408P 2008-12-31 2008-12-31
PCT/US2009/069930 WO2010078504A1 (en) 2008-12-31 2009-12-31 Nutraceuticals containing nitro fatty acids

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EP2384114A1 EP2384114A1 (en) 2011-11-09
EP2384114A4 true EP2384114A4 (en) 2013-10-23

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US (2) US8933255B2 (en)
EP (1) EP2384114A4 (en)
JP (1) JP2012513774A (en)
CN (2) CN102307464A (en)
AU (1) AU2009334476B2 (en)
CA (2) CA2929998A1 (en)
SG (1) SG172826A1 (en)
WO (1) WO2010078504A1 (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2679224A1 (en) 2007-08-01 2014-01-01 University of Pittsburgh of the Commonwealth System of Higher Education Nitro oleic acid modulation of type II diabetes
US20090326070A1 (en) 2008-05-01 2009-12-31 Complexa Inc. Vinyl substituted fatty acids
CN102099024B (en) 2008-06-19 2015-11-25 犹他大学研究基金会 The purposes of nitrated lipid in the treatment of the side effect of toxicity medical therapies
US20140024713A1 (en) 2008-06-19 2014-01-23 University Of Utah Research Foundation Use of nitrated lipids for treatment of side effects of toxic medical therapies
WO2013003689A2 (en) * 2011-06-30 2013-01-03 Nitromega Corp. Compositions containing nitro fatty acids
CN102307464A (en) * 2008-12-31 2012-01-04 尼特罗米加公司 Nutraceuticals containing nitro fatty acids
US20100286271A1 (en) * 2009-05-08 2010-11-11 Perricone Nicholas V Nitro-alkyl Compound Compositions
US20100286272A1 (en) * 2009-05-08 2010-11-11 Perricone Nicholas V Methods Of Use Of Nitroalkene Compositions In Dermatologic Applications
US20100286257A1 (en) * 2009-05-08 2010-11-11 Perricone Nicholas V Methods Of Use Of Nitroalkane Compositions In Dermatologic Applications To Prevent or Treat Skin Aging
JP2013500966A (en) 2009-07-31 2013-01-10 ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション Fatty acids as anti-inflammatory agents
WO2011028618A1 (en) * 2009-08-26 2011-03-10 Kameron Jay Carlson Composition and method for reducing blood glucose levels
US8686167B2 (en) 2009-10-02 2014-04-01 Complexa, Inc. Heteroatom containing substituted fatty acids
US8563609B2 (en) 2010-05-13 2013-10-22 Nitromega Corp. Nitro fatty acids - neuroprotection and/or inhibition of cognitive decline
WO2012006014A2 (en) * 2010-06-28 2012-01-12 Complexa, Inc. Multi-component pharmaceuticals for treating diabetes
WO2012037311A1 (en) * 2010-09-17 2012-03-22 Maine Natural Health, Inc. Compositions containing omega-3 oil and uses thereof
US9415035B2 (en) 2010-09-17 2016-08-16 Maine Natural Health Company, Inc. Compositions containing omega-3 oil with an anti-inflammatory agent and uses thereof
EP2744491B1 (en) 2011-08-19 2020-07-29 The University of Utah Research Foundation Combination therapy with nitrated lipids and inhibitors of the renin-angiotensin-aldosterone system
US9271952B2 (en) * 2011-10-11 2016-03-01 Complexa, Inc. Compositions and methods for treating nephropathy
US10874635B2 (en) 2011-10-21 2020-12-29 First Tech International Limited Tocotrienol compositions
KR101466617B1 (en) * 2011-11-17 2014-11-28 한미약품 주식회사 ORAL COMPLEX FORMULATION COMPRISING OMEGA-3 FATTY ACID AND HMG-CoA REDUCTASE INHIBITOR WITH IMPROVED STABILITY
WO2013072767A1 (en) * 2011-11-18 2013-05-23 Pronova Biopharma Norge As Compositions and preconcentrates comprising at least one salicylate and omega-3 fatty acid oil mixture
US20140271844A1 (en) * 2013-03-15 2014-09-18 Nitromega Corp. Compositions containing nitro fatty acids
US20160081962A1 (en) * 2013-05-10 2016-03-24 Nitromega Corp. Nutritional or dietary supplements containing fatty acids and nitrite
JP6240430B2 (en) * 2013-08-07 2017-11-29 クラシエフーズ株式会社 Highly stretchable chewing gum and combination chewing gum using the same
KR101540004B1 (en) * 2014-09-23 2015-07-29 최임영 Composition of Health Functional Foods for Improving of Blood sugar, Blood pressure, Blood Circulation and Cholesterol into Blood
US20180092948A1 (en) * 2015-04-02 2018-04-05 Aobiome Llc Production of nitro-fatty acids and nitro-hydrocarbons by ammonia oxidizing bacteria
PT3865484T (en) 2015-07-07 2024-01-30 H Lundbeck As Pde9 inhibitor with imidazo pyrazinone backbone for treatment of peripheral diseases
US11544306B2 (en) 2015-09-22 2023-01-03 Northern Light Group, Llc System and method for concept-based search summaries
US11886477B2 (en) 2015-09-22 2024-01-30 Northern Light Group, Llc System and method for quote-based search summaries
CN108430466A (en) * 2015-10-02 2018-08-21 康普莱克夏公司 It is prevented, treated using the activation aliphatic acid of therapeutically effective amount and reverse disease
US11226946B2 (en) 2016-04-13 2022-01-18 Northern Light Group, Llc Systems and methods for automatically determining a performance index
ES2638195B1 (en) * 2016-04-18 2018-08-02 Bioiberica, S.A. SKIN COMPOSITIONS
JP7523905B2 (en) * 2016-09-29 2024-07-29 ソシエテ・デ・プロデュイ・ネスレ・エス・アー Omega-3 fatty acids, nitric oxide releasing compounds and vitamin B12 as neuroprotective agents in non-demented patients
WO2018188771A1 (en) * 2017-04-11 2018-10-18 Nestec S.A. Omega-3 fatty acid and vitamin d levels to identify and attenuate cognitive aging in individuals
CA3054846A1 (en) * 2017-04-11 2018-10-18 Societe Des Produits Nestle S.A. Omega-3 fatty acid and vitamin d levels to identify and attenuate cognitive aging in individuals
EP3388061A1 (en) * 2017-04-11 2018-10-17 Nestec S.A. Omega 3 fatty acids, no releasing compound, vitamin b12 and choline as neuroprotectant in patients with no dementia
BR112020012864A2 (en) * 2018-02-02 2020-12-29 Société des Produits Nestlé S.A. STABILIZATION OF OMEGA-3 FATTY ACIDS WITH bran
SI3801526T1 (en) 2018-05-25 2024-05-31 Cardurion Pharmaceuticals, Inc. Monohydrate and crystalline forms of 6-((3s,4s)-4-methyl-1- (pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-3-tetrahydropyran-4-yl- 7h-imid azo (1,5- a) pyrazin-8-one
PE20221516A1 (en) 2019-11-22 2022-10-04 Univ Andres Bello AGAROPHYTON CHILENSIS EXTRACT, RICH IN FREE FATTY ACIDS, AS A NUTRACEUTICAL OR NUTRITIONAL SUPPLEMENT USEFUL TO MODULATE PPARy ACTIVITY
CN114366690A (en) * 2022-02-10 2022-04-19 广州天然国度生物科技有限公司 Composition, application and cosmetic

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422111A (en) * 1991-01-23 1995-06-06 Coletica Polyose/fatty acid complex product with a high fatty acid content, use as an emulsifier or moisturizer and emulsifying or moisturizing composition in which it is present
US6221377B1 (en) * 1995-11-13 2001-04-24 Pitmy International N.V. Administration media for analgesic, anti-inflammatory and anti-pyretic drugs containing nitrous oxide and pharmaceutical compositions containing such media and drugs
US20030092762A1 (en) * 1999-09-17 2003-05-15 Antonio Ferrante Anti-inflammatory nitro and thia-fatty acids
WO2007092085A2 (en) * 2005-12-20 2007-08-16 Howard Murad Fragranced therapeutic delivery system
US20070232579A1 (en) * 2004-04-28 2007-10-04 Uab Research Foundation, The Nitrated Lipids and Methods of Making and Using Thereof
WO2009017802A1 (en) * 2007-08-01 2009-02-05 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Nitro-fattyacid modulation of type ii diabetes
WO2009134383A2 (en) * 2008-05-01 2009-11-05 Complexa Inc. Vinyl substituted fatty acids
WO2009155439A2 (en) * 2008-06-19 2009-12-23 University Of Utah Research Foundation Use of nitrated lipids for treatment of side effects of toxic medical therapies
WO2010014889A2 (en) * 2008-08-01 2010-02-04 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Nitro fatty acids as regiomers and related mimetics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2223943A (en) * 1988-10-21 1990-04-25 Tillotts Pharma Ag Oral disage forms of omega-3 polyunsaturated acids
CA2373605A1 (en) * 1999-05-07 2000-11-16 Trustees Of Tufts College Immune stimulating dietary supplement and methods of use thereof
US6346231B1 (en) * 1999-10-06 2002-02-12 Joar Opheim Flavored gelatin capsule and method of manufacture
US7670612B2 (en) * 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
US20060020031A1 (en) * 2004-07-26 2006-01-26 Roger Berlin Compositions containing policosanol and omega-3 fatty acids and their pharmaceutical uses
CN102307464A (en) * 2008-12-31 2012-01-04 尼特罗米加公司 Nutraceuticals containing nitro fatty acids

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422111A (en) * 1991-01-23 1995-06-06 Coletica Polyose/fatty acid complex product with a high fatty acid content, use as an emulsifier or moisturizer and emulsifying or moisturizing composition in which it is present
US6221377B1 (en) * 1995-11-13 2001-04-24 Pitmy International N.V. Administration media for analgesic, anti-inflammatory and anti-pyretic drugs containing nitrous oxide and pharmaceutical compositions containing such media and drugs
US20030092762A1 (en) * 1999-09-17 2003-05-15 Antonio Ferrante Anti-inflammatory nitro and thia-fatty acids
US20070232579A1 (en) * 2004-04-28 2007-10-04 Uab Research Foundation, The Nitrated Lipids and Methods of Making and Using Thereof
WO2007092085A2 (en) * 2005-12-20 2007-08-16 Howard Murad Fragranced therapeutic delivery system
WO2009017802A1 (en) * 2007-08-01 2009-02-05 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Nitro-fattyacid modulation of type ii diabetes
WO2009134383A2 (en) * 2008-05-01 2009-11-05 Complexa Inc. Vinyl substituted fatty acids
WO2009155439A2 (en) * 2008-06-19 2009-12-23 University Of Utah Research Foundation Use of nitrated lipids for treatment of side effects of toxic medical therapies
WO2010014889A2 (en) * 2008-08-01 2010-02-04 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Nitro fatty acids as regiomers and related mimetics

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2010078504A1 *

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CN104288138A (en) 2015-01-21
JP2012513774A (en) 2012-06-21
AU2009334476A1 (en) 2011-07-21
US20150086625A1 (en) 2015-03-26
US8933255B2 (en) 2015-01-13
EP2384114A1 (en) 2011-11-09
WO2010078504A1 (en) 2010-07-08
CA2748743C (en) 2016-07-26
CA2748743A1 (en) 2010-07-08
CA2929998A1 (en) 2010-07-08
AU2009334476B2 (en) 2013-08-29
SG172826A1 (en) 2011-08-29
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