EP2274443A4 - Capture agents and related methods and systems for detecting and/or sorting targets - Google Patents
Capture agents and related methods and systems for detecting and/or sorting targetsInfo
- Publication number
- EP2274443A4 EP2274443A4 EP09729900A EP09729900A EP2274443A4 EP 2274443 A4 EP2274443 A4 EP 2274443A4 EP 09729900 A EP09729900 A EP 09729900A EP 09729900 A EP09729900 A EP 09729900A EP 2274443 A4 EP2274443 A4 EP 2274443A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- detecting
- systems
- related methods
- capture agents
- sorting targets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12347808P | 2008-04-09 | 2008-04-09 | |
PCT/US2009/040106 WO2009126828A2 (en) | 2008-04-09 | 2009-04-09 | Capture agents and related methods and systems for detecting and/or sorting targets |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2274443A2 EP2274443A2 (en) | 2011-01-19 |
EP2274443A4 true EP2274443A4 (en) | 2012-03-28 |
Family
ID=41162620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP09729900A Withdrawn EP2274443A4 (en) | 2008-04-09 | 2009-04-09 | Capture agents and related methods and systems for detecting and/or sorting targets |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP2274443A4 (en) |
JP (1) | JP2011518553A (en) |
CN (1) | CN102112626A (en) |
AU (1) | AU2009234162A1 (en) |
CA (1) | CA2721085A1 (en) |
WO (1) | WO2009126828A2 (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2155782A2 (en) | 2007-03-26 | 2010-02-24 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
EP3620465A1 (en) * | 2007-07-03 | 2020-03-11 | Dako Denmark A/S | Improved methods for generation, labeling and use of mhc multimers |
US10611818B2 (en) | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
DK2254592T3 (en) | 2008-02-28 | 2019-09-09 | Dako Denmark As | MHC multimers for Borrelia diagnostics and disease |
US10722562B2 (en) | 2008-07-23 | 2020-07-28 | Immudex Aps | Combinatorial analysis and repair |
US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
WO2010037402A1 (en) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Molecular vaccines for infectious disease |
US20100261292A1 (en) * | 2009-04-10 | 2010-10-14 | Meso Scale Technologies, Llc | Methods for Conducting Assays |
EP2628004A4 (en) | 2010-10-14 | 2014-08-20 | Meso Scale Technologies Llc | Reagent storage in an assay device |
EP2972366B1 (en) | 2013-03-15 | 2020-06-17 | Prognosys Biosciences, Inc. | Methods for detecting peptide/mhc/tcr binding |
AU2015271324B2 (en) * | 2014-06-06 | 2019-09-12 | Herlev Hospital | Determining antigen recognition through barcoding of MHC multimers |
WO2015188839A2 (en) | 2014-06-13 | 2015-12-17 | Immudex Aps | General detection and isolation of specific cells by binding of labeled molecules |
CN104165990B (en) * | 2014-07-24 | 2016-11-09 | 广州万联生物科技有限公司 | The chemical luminescence ELISA detection kit of chloramphenicol and using method |
KR102489353B1 (en) * | 2015-06-01 | 2023-01-17 | 캘리포니아 인스티튜트 오브 테크놀로지 | Compositions and methods for screening T cells with antigens to specific populations |
WO2017015064A1 (en) * | 2015-07-20 | 2017-01-26 | The Board Of Trustees Of The Leland Stanford Junior University | Detection phenotyping and quantitation of cells with multimeric binding reagent |
GB201516568D0 (en) * | 2015-09-18 | 2015-11-04 | Univ Birmingham | Apparatus and method for improved molecular detection |
WO2018183969A1 (en) * | 2017-03-30 | 2018-10-04 | California Institute Of Technology | Barcoded rapid assay platform for efficient analysis of candidate molecules and methods of making and using the platform |
JP6886854B2 (en) * | 2017-04-13 | 2021-06-16 | シスメックス株式会社 | Information acquisition method for test substances |
WO2021058692A1 (en) * | 2019-09-24 | 2021-04-01 | Qiagen Gmbh | Multimodal analysis of stabilized cell-containing bodily fluid samples |
WO2022066988A1 (en) * | 2020-09-24 | 2022-03-31 | University Of Cincinnati | Highly chemically stable aptamer sensors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10539561B1 (en) * | 2001-08-30 | 2020-01-21 | Customarray, Inc. | Enzyme-amplified redox microarray detection process |
CN1296492C (en) * | 2004-11-18 | 2007-01-24 | 博奥生物有限公司 | Biochip based method for detecting nucleic acid conjugated protein |
WO2007014267A2 (en) * | 2005-07-26 | 2007-02-01 | Oregon Health & Science University | Nanoparticle probes for capture, sorting and placement of targets |
AU2007281479A1 (en) * | 2006-08-02 | 2008-02-07 | California Institute Of Technology | Methods and systems for detecting and/or sorting targets |
EP2167633A4 (en) * | 2007-07-16 | 2014-12-24 | California Inst Of Techn | Microfluidic devices, methods and systems for detecting target molecules |
-
2009
- 2009-04-09 WO PCT/US2009/040106 patent/WO2009126828A2/en active Application Filing
- 2009-04-09 CA CA2721085A patent/CA2721085A1/en not_active Abandoned
- 2009-04-09 JP JP2011504182A patent/JP2011518553A/en not_active Withdrawn
- 2009-04-09 CN CN2009801216119A patent/CN102112626A/en active Pending
- 2009-04-09 EP EP09729900A patent/EP2274443A4/en not_active Withdrawn
- 2009-04-09 AU AU2009234162A patent/AU2009234162A1/en not_active Abandoned
Non-Patent Citations (8)
Title |
---|
BAILEY RYAN C ET AL: "DNA-encoded antibody libraries: A unified platform for multiplexed cell sorting and detection of genes and proteins", February 2007, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, VOL. 129, NR. 7, PAGE(S) 1959-1967, ISSN: 0002-7863, XP002667107 * |
DEVIREN GOKHAN ET AL: "Detection of antigen-specific T cells on p/MHC microarrays", January 2007, JOURNAL OF MOLECULAR RECOGNITION, VOL. 20, NR. 1, PAGE(S) 32-38, ISSN: 0952-3499, XP002667108 * |
JUNZO NORIMINE ET AL: "Quantitation of Anaplasma marginale major surface protein (MSP)1a and MSP2 epitope-specific CD4+ T lymphocytes using bovine DRB3*1101 and DRB3*1201 tetramers", IMMUNOGENETICS, SPRINGER, BERLIN, DE, vol. 58, no. 9, 19 August 2006 (2006-08-19), pages 726 - 739, XP019421864, ISSN: 1432-1211, DOI: 10.1007/S00251-006-0140-3 * |
KWONG GABRIEL A ET AL: "Modular Nucleic Acid Assembled p/MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells", July 2009, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, VOL. 131, NR. 28, PAGE(S) 9695-9703, ISSN: 0002-7863, XP002667106 * |
SANO T ET AL: "A streptavidin mutant containing a cysteine stretch that facilitates production of a variety of specific streptavidin conjugates", BIO/TECHNOLOGY, NATURE PUBLISHING CO. NEW YORK, US, vol. 11, no. 2, 1 February 1993 (1993-02-01), pages 201 - 206, XP001526159, ISSN: 0733-222X * |
SOEN YOAV ET AL: "Detection and characterization of cellular immune responses using peptide-MHC microarrays.", December 2003, PLOS BIOLOGY, VOL. 1, NR. 3 CITED DECEMBER 31, 2003, PAGE(S) 429-438 URL, XP002667110 * |
YANG JUNBAO ET AL: "In vivo biotinylation of the major histocompatibility complex (MHC) class II/peptide complex by coexpression of B irA enzyme for the generation of MHC class II/tetramers", HUMAN IMMUNOLOGY, NEW YORK, NY, US, vol. 65, no. 7, 1 July 2004 (2004-07-01), pages 692 - 699, XP002455388, ISSN: 0198-8859, DOI: 10.1016/J.HUMIMM.2004.04.001 * |
YOKOUCHI HIROSHI ET AL: "Tetramer-blocking assay for defining antigen-specific cytotoxic T lymphocytes using peptide-MHC tetramer", February 2006, CANCER SCIENCE, VOL. 97, NR. 2, PAGE(S) 148-154, ISSN: 1347-9032, XP002667109 * |
Also Published As
Publication number | Publication date |
---|---|
WO2009126828A3 (en) | 2010-03-04 |
AU2009234162A1 (en) | 2009-10-15 |
WO2009126828A2 (en) | 2009-10-15 |
CN102112626A (en) | 2011-06-29 |
JP2011518553A (en) | 2011-06-30 |
CA2721085A1 (en) | 2009-10-15 |
EP2274443A2 (en) | 2011-01-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20101105 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA RS |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: HEATH, JAMES, R. Inventor name: WITTE, OWEN Inventor name: RIBAS, ANTONI Inventor name: RADU, CAIUS G. Inventor name: KWONG, GABRIEL, A. |
|
DAX | Request for extension of the european patent (deleted) | ||
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 15/10 20060101ALI20120215BHEP Ipc: G01N 33/68 20060101ALI20120215BHEP Ipc: G01N 33/53 20060101ALI20120215BHEP Ipc: C12Q 1/68 20060101AFI20120215BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20120224 |
|
17Q | First examination report despatched |
Effective date: 20131002 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20140213 |