EP2097522A4 - Method, kit and initiators for genetic identification of mycobacterium bovis bcg variety moreau-rj, method for monitoring feasibility of bcg moreau-rj and expression of genes, and products with immunological activity - Google Patents

Method, kit and initiators for genetic identification of mycobacterium bovis bcg variety moreau-rj, method for monitoring feasibility of bcg moreau-rj and expression of genes, and products with immunological activity

Info

Publication number
EP2097522A4
EP2097522A4 EP07815763A EP07815763A EP2097522A4 EP 2097522 A4 EP2097522 A4 EP 2097522A4 EP 07815763 A EP07815763 A EP 07815763A EP 07815763 A EP07815763 A EP 07815763A EP 2097522 A4 EP2097522 A4 EP 2097522A4
Authority
EP
European Patent Office
Prior art keywords
moreau
bcg
initiators
genes
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07815763A
Other languages
German (de)
French (fr)
Other versions
EP2097522A2 (en
Inventor
Wim Maurits Sylvain Degrave
Leila De Mendonca Lima
Otto Thomas Dan
Luiz Roberto Ribeiro Castello-Branco
Filho Germano Gerhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fundacao Oswaldo Cruz
Original Assignee
Fundacao Oswaldo Cruz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao Oswaldo Cruz filed Critical Fundacao Oswaldo Cruz
Publication of EP2097522A2 publication Critical patent/EP2097522A2/en
Publication of EP2097522A4 publication Critical patent/EP2097522A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/32—Mycobacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP07815763A 2006-11-23 2007-11-23 Method, kit and initiators for genetic identification of mycobacterium bovis bcg variety moreau-rj, method for monitoring feasibility of bcg moreau-rj and expression of genes, and products with immunological activity Withdrawn EP2097522A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0604958-3A BRPI0604958B1 (en) 2006-11-23 2006-11-23 Kit for distinguishing mycobacterium tuberculosis, m. bovis, m. bovis bcg in a sample, and method to distinguish mycobacterium tuberculosis, m. bovis, m. bovis bcg
PCT/BR2007/000322 WO2008061331A2 (en) 2006-11-23 2007-11-23 Genetic identification of mycobacterium bovis bcg variety moreau-rj

Publications (2)

Publication Number Publication Date
EP2097522A2 EP2097522A2 (en) 2009-09-09
EP2097522A4 true EP2097522A4 (en) 2010-02-10

Family

ID=39430082

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07815763A Withdrawn EP2097522A4 (en) 2006-11-23 2007-11-23 Method, kit and initiators for genetic identification of mycobacterium bovis bcg variety moreau-rj, method for monitoring feasibility of bcg moreau-rj and expression of genes, and products with immunological activity

Country Status (3)

Country Link
EP (1) EP2097522A4 (en)
BR (1) BRPI0604958B1 (en)
WO (1) WO2008061331A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101912606A (en) * 2010-08-02 2010-12-15 吉林大学 Tubercle bacillus calmette-guerin (BCG) with strengthened molecular marking and immunoprotection performance and construction method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU623236B2 (en) * 1989-02-22 1992-05-07 Cogent Limited Probes, kits and methods for the detection and differentiation of mycobacteria
US5700683A (en) * 1995-02-17 1997-12-23 Pathogenesis Corporation Virulence-attenuating genetic deletions deleted from mycobacterium BCG
AU2006202498A1 (en) * 1997-08-14 2006-07-06 Institut Pasteur Polypeptide nucleic sequences exported from mycobacteria, vectors comprising same and uses for diagnosing and preventing tuberculosis
US6291190B1 (en) * 1998-08-25 2001-09-18 The Board Of Trustees Of The Leland Stanford Junior University Molecular differences between species of the M. tuberculosis complex
US20040018574A1 (en) * 1998-08-25 2004-01-29 Marcel Behr Molecular differences between species of the M. tuberculosis complex
ES2286212T3 (en) * 2002-02-25 2007-12-01 Pasteur Institut SPECIFICALLY DELETED SEQUENCES OF THE MYCOBACTERIUM TUBERCULOSIS GENOME, AND ITS USE IN THE DIAGNOSIS AND AS VACCINES.
EP2397856B1 (en) * 2006-03-14 2013-11-13 Oregon Health and Science University Methods for detecting a mycobacterium tuberculosis infection

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BEHR M A ET AL: "Comparative genomics of BCG vaccines by whole-genome DNA microarray", SCIENCE (WASHINGTON D C), vol. 284, no. 5419, 28 May 1999 (1999-05-28), pages 1520 - 1523, XP002558331, ISSN: 0036-8075 *
BROSCH ROLAND ET AL: "Comparative genomics uncovers large tandem chromosomal duplications in Mycobacterium bovis BCG pasteur", YEAST, vol. 17, no. 2, 30 June 2000 (2000-06-30), pages 111 - 123, XP008115720, ISSN: 0749-503X *
GARNIER T ET AL: "THE COMPLETE GENOME SEQUENCE OF MYCOBACTERIUM BOVIS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 100, no. 13, 24 June 2003 (2003-06-24), pages 7877 - 7882, XP001205229, ISSN: 0027-8424 *
KONG Y ET AL: "Population-based study of deletions in five different genomic regions of Mycobacterium tuberculosis and possible clinical relevance of the deletions.", JOURNAL OF CLINICAL MICROBIOLOGY NOV 2006, vol. 44, no. 11, 6 September 2006 (2006-09-06), pages 3940 - 3946, XP002558330, ISSN: 0095-1137 *
TSOLAKI ANTHONY G ET AL: "Genomic deletions classify the Beijing/W strains as a distinct genetic lineage of Mycobacterium tuberculosis.", JOURNAL OF CLINICAL MICROBIOLOGY JUL 2005, vol. 43, no. 7, July 2005 (2005-07-01), pages 3185 - 3191, XP002558329, ISSN: 0095-1137 *

Also Published As

Publication number Publication date
EP2097522A2 (en) 2009-09-09
WO2008061331A2 (en) 2008-05-29
WO2008061331A3 (en) 2008-11-06
BRPI0604958A (en) 2008-07-08
BRPI0604958B1 (en) 2022-05-17

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