EP2013618A4 - Investigation of mucosa dryness conditions - Google Patents

Investigation of mucosa dryness conditions

Info

Publication number
EP2013618A4
EP2013618A4 EP07748663A EP07748663A EP2013618A4 EP 2013618 A4 EP2013618 A4 EP 2013618A4 EP 07748663 A EP07748663 A EP 07748663A EP 07748663 A EP07748663 A EP 07748663A EP 2013618 A4 EP2013618 A4 EP 2013618A4
Authority
EP
European Patent Office
Prior art keywords
investigation
mucosa
dryness conditions
conditions
mucosa dryness
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP07748663A
Other languages
German (de)
French (fr)
Other versions
EP2013618A1 (en
EP2013618B1 (en
Inventor
Roger Beuerman
Lei Zhou
Shouping Liu
He Yang
Donald Tan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agency for Science Technology and Research Singapore
Singapore Health Services Pte Ltd
Original Assignee
Agency for Science Technology and Research Singapore
Singapore Health Services Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency for Science Technology and Research Singapore, Singapore Health Services Pte Ltd filed Critical Agency for Science Technology and Research Singapore
Publication of EP2013618A1 publication Critical patent/EP2013618A1/en
Publication of EP2013618A4 publication Critical patent/EP2013618A4/en
Application granted granted Critical
Publication of EP2013618B1 publication Critical patent/EP2013618B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/16—Ophthalmology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/811—Drug, bio-affecting and body treating compositions involving sex selection or contraception
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
EP07748663.7A 2006-04-28 2007-04-26 Investigation of mucosa dryness conditions Not-in-force EP2013618B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79567606P 2006-04-28 2006-04-28
PCT/SG2007/000118 WO2007126391A1 (en) 2006-04-28 2007-04-26 Investigation of mucosa dryness conditions

Publications (3)

Publication Number Publication Date
EP2013618A1 EP2013618A1 (en) 2009-01-14
EP2013618A4 true EP2013618A4 (en) 2010-11-03
EP2013618B1 EP2013618B1 (en) 2013-04-10

Family

ID=38655813

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07748663.7A Not-in-force EP2013618B1 (en) 2006-04-28 2007-04-26 Investigation of mucosa dryness conditions

Country Status (4)

Country Link
US (1) US8080428B2 (en)
EP (1) EP2013618B1 (en)
JP (1) JP5420396B2 (en)
WO (1) WO2007126391A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2451969A2 (en) * 2009-07-07 2012-05-16 University Of Southern California Biomarkers for the early detection of autoimmune diseases
US9687523B2 (en) 2010-02-04 2017-06-27 University Of Southern California Compositions and methods for the treatment of sjörgren's syndrome
CA2802631C (en) 2010-06-14 2019-12-17 Lykera Biomed Sa S100a4 antibodies and therapeutic uses thereof
EP2418491A1 (en) * 2010-08-10 2012-02-15 Bioftalmik, S.L. Method for the diagnosis of dry eye and blepharitis
US9606117B2 (en) 2011-01-13 2017-03-28 University Of Southern California Bioassay for the early detection of autoimmune diseases
JP6296533B2 (en) * 2013-09-03 2018-03-20 株式会社 資生堂 Method for quantifying cysteine and cystine
WO2015038069A1 (en) * 2013-09-11 2015-03-19 Singapore Health Services Pte Ltd Identification of novel biomarkers of flares of systemic lupus erythematosus
WO2015154052A1 (en) 2014-04-04 2015-10-08 Mayo Foundation For Medical Education And Research Isotyping immunoglobulins using accurate molecular mass
WO2017053932A1 (en) 2015-09-24 2017-03-30 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
WO2017148951A1 (en) * 2016-02-29 2017-09-08 Santen Sas Gene signature for the prognosis of dry eye disease
CA3034608A1 (en) 2016-08-24 2018-03-01 The University Of Melbourne Diagnostic methods and device
AU2017325022B2 (en) 2016-09-07 2022-10-13 Mayo Foundation For Medical Education And Research Identification and monitoring of cleaved immunoglobulins by molecular mass
FR3060755A1 (en) * 2016-12-16 2018-06-22 L'oreal DIAGNOSTIC METHOD FOR A SKIN WITH DROUGHT SIGNS
EP3681528A4 (en) 2017-09-13 2021-07-21 Mayo Foundation for Medical Education and Research Identification and monitoring of apoptosis inhibitor of macrophage
US20210364534A1 (en) * 2018-10-24 2021-11-25 The Board Of Trustees Of The University Of Illinois Methods of using histatin for diagnosing and treating a dry eye disease or other ocular diseases
US20220221473A1 (en) * 2019-04-26 2022-07-14 Senju Pharmaceutical Co., Ltd. Eye disease marker

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10017249A1 (en) * 2000-04-06 2001-10-11 Peter Solisch Highly sensitive detection of malignant tumors, comprises immunological determination of RiV particles using specific antibodies
WO2002077176A2 (en) * 2001-03-22 2002-10-03 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Aberrantly expressed proteins in laser capture microdissected tumors
WO2004081033A2 (en) * 2003-03-11 2004-09-23 National Institutes Of Health Synthesis of proteins by cell-free protein expression
US20060051744A1 (en) * 2004-06-30 2006-03-09 Austin Kimberly M Feline infectious peritonitis (FIP) and systemic multi-organ coronavirus biomarkers and screening methods
WO2007057746A2 (en) * 2005-05-27 2007-05-24 Aurelium Biopharma Inc. Focused microarray and methods of diagnosing chemotherapeutic drug resistance in a cancer cell

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10017249A1 (en) * 2000-04-06 2001-10-11 Peter Solisch Highly sensitive detection of malignant tumors, comprises immunological determination of RiV particles using specific antibodies
WO2002077176A2 (en) * 2001-03-22 2002-10-03 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Aberrantly expressed proteins in laser capture microdissected tumors
WO2004081033A2 (en) * 2003-03-11 2004-09-23 National Institutes Of Health Synthesis of proteins by cell-free protein expression
US20060051744A1 (en) * 2004-06-30 2006-03-09 Austin Kimberly M Feline infectious peritonitis (FIP) and systemic multi-organ coronavirus biomarkers and screening methods
WO2007057746A2 (en) * 2005-05-27 2007-05-24 Aurelium Biopharma Inc. Focused microarray and methods of diagnosing chemotherapeutic drug resistance in a cancer cell

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GRUS F H ET AL: "SELDI-TOF-MS ProteinChip profiling of tears from patients with dry eye", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY, US LNKD- DOI:10.1167/IOVS.04-0448, vol. 46, no. 3, 1 January 2005 (2005-01-01), pages 863 - 876, XP003024747, ISSN: 0146-0404 *
MACKIE I A ET AL: "Diagnostic implications of tear protein profiles", BRITISH JOURNAL OF OPHTHALMOLOGY, LONDON, GB LNKD- DOI:10.1136/BJO.68.5.321, vol. 68, no. 5, 1 January 1984 (1984-01-01), pages 321 - 324, XP003024748, ISSN: 0007-1161 *
MACKIE I AND SEAL D V: "Confirmatory tests for the dry eye of Sjögren's syndrome", SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, ALMQVIST & WIKSELL PERIODICAL CO., STOCKHOLM, SE, vol. SUPPL. 61, 1 January 1986 (1986-01-01), pages 220 - 223, XP008107793, ISSN: 0300-9742 *
See also references of WO2007126391A1 *
ZHOU LEI ET AL: "Identification of tear fluid biomarkers in dry eye syndrome using iTRAQ quantitative proteomics.", JOURNAL OF PROTEOME RESEARCH NOV 2009 LNKD- PUBMED:19705875, vol. 8, no. 11, November 2009 (2009-11-01), pages 4889 - 4905, XP002601635, ISSN: 1535-3907 *

Also Published As

Publication number Publication date
JP2009535620A (en) 2009-10-01
WO2007126391A8 (en) 2009-07-23
WO2007126391A1 (en) 2007-11-08
EP2013618A1 (en) 2009-01-14
US20090258828A1 (en) 2009-10-15
US8080428B2 (en) 2011-12-20
JP5420396B2 (en) 2014-02-19
EP2013618B1 (en) 2013-04-10

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