EP1904807A4 - Systems and methods for a multiple angle light scattering (mals) instrument having two-dimensional dectector array - Google Patents

Systems and methods for a multiple angle light scattering (mals) instrument having two-dimensional dectector array

Info

Publication number
EP1904807A4
EP1904807A4 EP06773081A EP06773081A EP1904807A4 EP 1904807 A4 EP1904807 A4 EP 1904807A4 EP 06773081 A EP06773081 A EP 06773081A EP 06773081 A EP06773081 A EP 06773081A EP 1904807 A4 EP1904807 A4 EP 1904807A4
Authority
EP
European Patent Office
Prior art keywords
dectector
mals
instrument
array
dimensional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06773081A
Other languages
German (de)
French (fr)
Other versions
EP1904807A2 (en
Inventor
John A Adams
Scott H Bloom
Victor J Chan
Kristina M Crousore
Joseph S Gottlieb
Oscar Hemberg
John J Lyon
Brett A Spivey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JMAR Research Inc
Original Assignee
JMAR Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/381,346 external-priority patent/US7564551B2/en
Application filed by JMAR Research Inc filed Critical JMAR Research Inc
Publication of EP1904807A2 publication Critical patent/EP1904807A2/en
Publication of EP1904807A4 publication Critical patent/EP1904807A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • G01N15/1433Signal processing using image recognition
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/18Water
    • G01N33/1893Water using flow cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/019Biological contaminants; Fouling

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Signal Processing (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Radar Systems And Details Thereof (AREA)
EP06773081A 2005-06-13 2006-06-13 Systems and methods for a multiple angle light scattering (mals) instrument having two-dimensional dectector array Withdrawn EP1904807A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69053505P 2005-06-13 2005-06-13
US11/381,346 US7564551B2 (en) 2005-05-02 2006-05-02 Systems and methods for a high capture angle, multiple angle light scattering (MALS) instrument
PCT/US2006/023043 WO2006135902A2 (en) 2005-06-13 2006-06-13 Systems and methods for a multiple angle light scattering (mals) instrument having two-dimensional dectector array

Publications (2)

Publication Number Publication Date
EP1904807A2 EP1904807A2 (en) 2008-04-02
EP1904807A4 true EP1904807A4 (en) 2011-04-20

Family

ID=37532906

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06773081A Withdrawn EP1904807A4 (en) 2005-06-13 2006-06-13 Systems and methods for a multiple angle light scattering (mals) instrument having two-dimensional dectector array

Country Status (2)

Country Link
EP (1) EP1904807A4 (en)
WO (1) WO2006135902A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11346762B2 (en) * 2018-01-23 2022-05-31 Becton, Dickinson And Company Systems for dynamic light detection obscuration and methods for using thereof

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2044445A (en) * 1979-01-02 1980-10-15 Coulter Electronics Measuring scatter distribution
US4606636A (en) * 1983-10-25 1986-08-19 Universite De Saint-Etienne Optical apparatus for identifying the individual multiparametric properties of particles or bodies in a continuous flow
US5101113A (en) * 1989-05-16 1992-03-31 Arizona Board Of Regents Ensemble scattering particle sizing system with axial spatial resolution
US5141609A (en) * 1990-11-16 1992-08-25 The Trustees Of The Leland Stanford Junior University Method and device employing time-delayed integration for detecting sample components after separation
WO1996029571A1 (en) * 1995-03-23 1996-09-26 Beckman Instruments, Inc. Automated optical alignment system and method using raman scattering of capillary tube contents
US20020071121A1 (en) * 1999-01-25 2002-06-13 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US20030227545A1 (en) * 2002-06-10 2003-12-11 Hideki Soya Photographic apparatus and photographic method using same
US20040011975A1 (en) * 2002-07-17 2004-01-22 Nicoli David F. Sensors and methods for high-sensitivity optical particle counting and sizing

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2101113A (en) 1933-02-16 1937-12-07 Teletypesetter Corp Control unit for line casting machines
GB8509492D0 (en) * 1985-04-12 1985-05-15 Plessey Co Plc Optical assay
KR970007077B1 (en) * 1987-03-13 1997-05-02 코울터 일렉트로닉스 인커퍼레이티드 Multi-part diefferential analyzing apparatus using light scatter techniques
US5760900A (en) * 1989-03-18 1998-06-02 Canon Kabushiki Kaisha Method and apparatus for optically measuring specimen
JP3290786B2 (en) * 1993-11-26 2002-06-10 シスメックス株式会社 Particle analyzer
GB9610700D0 (en) * 1996-05-22 1996-07-31 Moor Instr Ltd Apparatus for imaging microvascular blood flow
GB9818351D0 (en) * 1998-08-22 1998-10-14 Malvern Instr Ltd Improvements relating to the measurement of particle size distribution
EP1328894A4 (en) * 2000-08-25 2005-11-09 Amnis Corp Measuring the velocity of small moving objects such as cells
US6774995B2 (en) * 2001-08-03 2004-08-10 Pointsource Technologies, Llc Identification of particles in fluid
US6710874B2 (en) * 2002-07-05 2004-03-23 Rashid Mavliev Method and apparatus for detecting individual particles in a flowable sample

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2044445A (en) * 1979-01-02 1980-10-15 Coulter Electronics Measuring scatter distribution
US4606636A (en) * 1983-10-25 1986-08-19 Universite De Saint-Etienne Optical apparatus for identifying the individual multiparametric properties of particles or bodies in a continuous flow
US5101113A (en) * 1989-05-16 1992-03-31 Arizona Board Of Regents Ensemble scattering particle sizing system with axial spatial resolution
US5141609A (en) * 1990-11-16 1992-08-25 The Trustees Of The Leland Stanford Junior University Method and device employing time-delayed integration for detecting sample components after separation
WO1996029571A1 (en) * 1995-03-23 1996-09-26 Beckman Instruments, Inc. Automated optical alignment system and method using raman scattering of capillary tube contents
US20020071121A1 (en) * 1999-01-25 2002-06-13 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US20030227545A1 (en) * 2002-06-10 2003-12-11 Hideki Soya Photographic apparatus and photographic method using same
US20040011975A1 (en) * 2002-07-17 2004-01-22 Nicoli David F. Sensors and methods for high-sensitivity optical particle counting and sizing

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2006135902A2 *

Also Published As

Publication number Publication date
WO2006135902A2 (en) 2006-12-21
WO2006135902A3 (en) 2007-11-08
EP1904807A2 (en) 2008-04-02

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Ipc: G01N 15/14 20060101ALI20110317BHEP

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17Q First examination report despatched

Effective date: 20121221

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Owner name: JMAR RESEARCH, INC.

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