EP1885855A4 - Cytokine receptor modulators and uses thereof - Google Patents

Cytokine receptor modulators and uses thereof

Info

Publication number
EP1885855A4
EP1885855A4 EP06795318A EP06795318A EP1885855A4 EP 1885855 A4 EP1885855 A4 EP 1885855A4 EP 06795318 A EP06795318 A EP 06795318A EP 06795318 A EP06795318 A EP 06795318A EP 1885855 A4 EP1885855 A4 EP 1885855A4
Authority
EP
European Patent Office
Prior art keywords
receptor modulators
cytokine receptor
cytokine
modulators
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06795318A
Other languages
German (de)
French (fr)
Other versions
EP1885855A2 (en
Inventor
Sylvain Chemtob
Christiane Quiniou
Martin Beauchamp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valorisation HSJ LP
Original Assignee
Valorisation HSJ LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/CA2005/000691 external-priority patent/WO2005105830A1/en
Application filed by Valorisation HSJ LP filed Critical Valorisation HSJ LP
Priority to EP11001894A priority Critical patent/EP2366786A3/en
Publication of EP1885855A2 publication Critical patent/EP1885855A2/en
Publication of EP1885855A4 publication Critical patent/EP1885855A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Ophthalmology & Optometry (AREA)
EP06795318A 2005-05-05 2006-05-05 Cytokine receptor modulators and uses thereof Withdrawn EP1885855A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP11001894A EP2366786A3 (en) 2005-05-05 2006-05-05 Cytokine receptor modulators and uses thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/CA2005/000691 WO2005105830A1 (en) 2004-05-05 2005-05-05 Interleukin-1 receptor antagonists, compositions, and methods of treatment
US75136005P 2005-12-16 2005-12-16
PCT/IB2006/002298 WO2007004060A2 (en) 2005-05-05 2006-05-05 Cytokine receptor modulators and uses thereof

Publications (2)

Publication Number Publication Date
EP1885855A2 EP1885855A2 (en) 2008-02-13
EP1885855A4 true EP1885855A4 (en) 2009-03-04

Family

ID=37604843

Family Applications (2)

Application Number Title Priority Date Filing Date
EP11001894A Withdrawn EP2366786A3 (en) 2005-05-05 2006-05-05 Cytokine receptor modulators and uses thereof
EP06795318A Withdrawn EP1885855A4 (en) 2005-05-05 2006-05-05 Cytokine receptor modulators and uses thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP11001894A Withdrawn EP2366786A3 (en) 2005-05-05 2006-05-05 Cytokine receptor modulators and uses thereof

Country Status (6)

Country Link
US (2) US20090048161A1 (en)
EP (2) EP2366786A3 (en)
JP (1) JP2008542685A (en)
AU (1) AU2006264567A1 (en)
CA (1) CA2650656A1 (en)
WO (1) WO2007004060A2 (en)

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US8618054B2 (en) 2004-05-05 2013-12-31 Valorisation-Rechereche Société en Commandite Interleukin-1 receptor antagonists, compositions, and methods of treatment
ES2402823T3 (en) 2006-06-01 2013-05-09 Institut De Cardiologie De Montreal Compound for use in the treatment of valve stenosis
MX2009013269A (en) 2007-06-05 2010-04-21 Univ Yale Inhibitors of receptor tyrosine kinases and methods of use thereof.
EP2288621A4 (en) * 2007-07-06 2012-01-04 Valorisation Hsj Soc En Commandite Il-23 receptor antagonists and uses thereof
US20110135661A1 (en) * 2008-02-19 2011-06-09 Universite De Montreal Treatment and prevention of dry age-related macular degeneration by activating cd36
WO2009120903A2 (en) * 2008-03-26 2009-10-01 Cellerant Therapeutics, Inc. Cytokine receptors associated with myelogenous haematological proliferative disorders and uses thereof
RU2532222C2 (en) 2009-02-16 2014-10-27 Серенис Терапьютикс Холдинг С.А, A-i apolipoprotein mimetics
AU2014268255B2 (en) * 2009-02-16 2016-04-21 Cerenis Therapeutics Holding Sa Apolipoprotein a-i mimics
DK2403935T3 (en) 2009-03-04 2017-09-11 Univ Pennsylvania COMPOSITIONS CONTAINING ANGIOGENIC FACTORS AND METHODS OF USE THEREOF
WO2010106441A2 (en) * 2009-03-20 2010-09-23 Centre Hospitalier Universitaire Sainte-Justine Peptidomimetics for modulating interleukin-1 receptor
WO2010124262A1 (en) * 2009-04-24 2010-10-28 Allostera Pharma Inc. Methods of identification of allosteramers and uses thereof
EP2668210B1 (en) 2011-01-26 2020-06-17 Celldex Therapeutics, Inc. Anti-kit antibodies and uses thereof
WO2012106556A2 (en) 2011-02-02 2012-08-09 Amgen Inc. Methods and compositons relating to inhibition of igf-1r
AU2012228769B2 (en) 2011-03-14 2016-09-08 Phlogo Aps Antagonists of the interleukin- 1 receptor
WO2013071056A2 (en) 2011-11-11 2013-05-16 Duke University Combination drug therapy for the treatment of solid tumors
US8980259B2 (en) 2012-07-20 2015-03-17 Novartis Ag Combination therapy
SG11201500489YA (en) 2012-07-25 2015-02-27 Kolltan Pharmaceuticals Inc Anti-kit antibodies and uses thereof
WO2014100772A1 (en) * 2012-12-21 2014-06-26 Cellerant Therapeutics, Inc. Antibodies that bind membrane-bound il1rap
CN113908269A (en) 2014-05-23 2022-01-11 塞尔德克斯医疗公司 Treatment of eosinophil or mast cell related disorders
WO2017129763A1 (en) 2016-01-28 2017-08-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of signet ring cell gastric cancer
CN107328943B (en) * 2017-07-28 2019-04-16 东曜药业有限公司 A kind of detection method and application of vascular endothelial growth factor biological activity
WO2019051494A1 (en) 2017-09-11 2019-03-14 Protagonist Therapeutics, Inc. Opioid agonist peptides and uses thereof
WO2019233605A1 (en) * 2018-06-08 2019-12-12 BioNTech SE Compositions and methods for diagnosis and treatment of cancer
TW202021618A (en) 2018-08-17 2020-06-16 美商23與我有限公司 Anti-il1rap antibodies and methods of use thereof

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WO2005105830A1 (en) * 2004-05-05 2005-11-10 Valorisation-Recherche, Societe En Commandite Interleukin-1 receptor antagonists, compositions, and methods of treatment
US20060094663A1 (en) * 2004-05-05 2006-05-04 Sylvain Chemtob Interleukin-1 receptor antagonists, compositions, and methods of treatment
US20070037210A1 (en) * 2002-10-24 2007-02-15 Sylvain Chemtob Cytokine receptor modulators, method of identifying same, and method of modulating cytokine receptors activity with same

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US4244946A (en) 1979-06-11 1981-01-13 The Salk Institute For Biological Studies Water-soluble peptides affecting gonadal function
US4305872A (en) 1979-10-19 1981-12-15 Kenneth Wingrove Polypeptide derivatives
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US5227466A (en) * 1988-06-30 1993-07-13 City Of Hope Insulin receptor binding site
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Also Published As

Publication number Publication date
US20110144014A1 (en) 2011-06-16
US20090048161A1 (en) 2009-02-19
EP2366786A2 (en) 2011-09-21
WO2007004060A3 (en) 2007-04-26
JP2008542685A (en) 2008-11-27
CA2650656A1 (en) 2007-01-11
AU2006264567A1 (en) 2007-01-11
WO2007004060A2 (en) 2007-01-11
EP2366786A3 (en) 2012-08-29
EP1885855A2 (en) 2008-02-13

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