EP1877004A4 - Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy - Google Patents
Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacyInfo
- Publication number
- EP1877004A4 EP1877004A4 EP06739478A EP06739478A EP1877004A4 EP 1877004 A4 EP1877004 A4 EP 1877004A4 EP 06739478 A EP06739478 A EP 06739478A EP 06739478 A EP06739478 A EP 06739478A EP 1877004 A4 EP1877004 A4 EP 1877004A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- methods
- long
- medical devices
- term efficacy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000007774 longterm Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical class C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16171630.3A EP3138531A1 (en) | 2005-03-23 | 2006-03-22 | Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66448805P | 2005-03-23 | 2005-03-23 | |
| US71508205P | 2005-09-08 | 2005-09-08 | |
| US72708005P | 2005-10-14 | 2005-10-14 | |
| US72719605P | 2005-10-14 | 2005-10-14 | |
| US72687805P | 2005-10-14 | 2005-10-14 | |
| US73257705P | 2005-10-17 | 2005-10-17 | |
| PCT/US2006/010700 WO2007032777A2 (en) | 2005-03-23 | 2006-03-22 | Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP16171630.3A Division EP3138531A1 (en) | 2005-03-23 | 2006-03-22 | Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1877004A2 EP1877004A2 (en) | 2008-01-16 |
| EP1877004A4 true EP1877004A4 (en) | 2012-01-25 |
Family
ID=37865406
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP16171630.3A Withdrawn EP3138531A1 (en) | 2005-03-23 | 2006-03-22 | Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy |
| EP06739478A Ceased EP1877004A4 (en) | 2005-03-23 | 2006-03-22 | Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP16171630.3A Withdrawn EP3138531A1 (en) | 2005-03-23 | 2006-03-22 | Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy |
Country Status (3)
| Country | Link |
|---|---|
| EP (2) | EP3138531A1 (en) |
| JP (1) | JP5242374B2 (en) |
| WO (1) | WO2007032777A2 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8394398B2 (en) | 1997-09-26 | 2013-03-12 | Abbott Laboratories | Methods of administering rapamycin analogs with anti-inflammatories using medical devices |
| US7357942B2 (en) | 1997-09-26 | 2008-04-15 | Abbott Laboratories | Compositions, systems, and kits for administering zotarolimus and paclitaxel to blood vessel lumens |
| US8257726B2 (en) | 1997-09-26 | 2012-09-04 | Abbott Laboratories | Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices |
| US7378105B2 (en) | 1997-09-26 | 2008-05-27 | Abbott Laboratories | Drug delivery systems, kits, and methods for administering zotarolimus and paclitaxel to blood vessel lumens |
| US8431145B2 (en) | 2004-03-19 | 2013-04-30 | Abbott Laboratories | Multiple drug delivery from a balloon and a prosthesis |
| EP2068932B1 (en) * | 2006-08-15 | 2013-11-06 | Abbott Laboratories | Compositions and drug-delivery systems comprising rapamycin analogs and paclitaxel |
| KR20100085179A (en) | 2007-09-04 | 2010-07-28 | 가부시키가이샤 니혼 스텐토 테크놀로지 | Stent for controlled drug release |
| US8951595B2 (en) | 2009-12-11 | 2015-02-10 | Abbott Cardiovascular Systems Inc. | Coatings with tunable molecular architecture for drug-coated balloon |
| US20130303496A1 (en) * | 2012-05-08 | 2013-11-14 | Abbott Cardiovascular Systems Inc. | Method Of Treating Vascular Lesions |
| US9610385B2 (en) * | 2013-03-07 | 2017-04-04 | Abbott Cardiovascular Systems Inc. | Method of fabricating an implantable medical device comprising a rapamycin derivative |
| EP4255357A1 (en) * | 2020-12-29 | 2023-10-11 | Sino Medical Sciences Technology Inc. | Drug eluting stent |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001087372A1 (en) * | 2000-05-12 | 2001-11-22 | Cordis Corporation | Drug combinations useful for prevention of restenosis |
| WO2002062335A2 (en) * | 2001-01-16 | 2002-08-15 | Vascular Therapies, Llc | Implantable device containing resorbable matrix material and anti-proliferative drugs for preventing or treating failure of hemodialysis vascular access and other vascular grafts |
| WO2003022807A2 (en) * | 2001-09-10 | 2003-03-20 | Abbott Laboratories | Medical devices containing rapamycin analogs |
| WO2004022124A1 (en) * | 2002-09-06 | 2004-03-18 | Abbott Laboratories | Medical device having hydration inhibitor |
| WO2005092406A1 (en) * | 2004-03-22 | 2005-10-06 | Advanced Cardiovascular Systems, Inc. | Phosphoryl choline coating compositions |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA737247B (en) | 1972-09-29 | 1975-04-30 | Ayerst Mckenna & Harrison | Rapamycin and process of preparation |
| US3993749A (en) | 1974-04-12 | 1976-11-23 | Ayerst Mckenna And Harrison Ltd. | Rapamycin and process of preparation |
| US4885171A (en) | 1978-11-03 | 1989-12-05 | American Home Products Corporation | Use of rapamycin in treatment of certain tumors |
| US4316885A (en) | 1980-08-25 | 1982-02-23 | Ayerst, Mckenna And Harrison, Inc. | Acyl derivatives of rapamycin |
| US4401653A (en) | 1981-03-09 | 1983-08-30 | Ayerst, Mckenna & Harrison Inc. | Combination of rapamycin and picibanil for the treatment of tumors |
| US4894366A (en) | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
| US4650803A (en) | 1985-12-06 | 1987-03-17 | University Of Kansas | Prodrugs of rapamycin |
| US5527337A (en) | 1987-06-25 | 1996-06-18 | Duke University | Bioabsorbable stent and method of making the same |
| US4916193A (en) | 1987-12-17 | 1990-04-10 | Allied-Signal Inc. | Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides |
| US5092877A (en) | 1988-09-01 | 1992-03-03 | Corvita Corporation | Radially expandable endoprosthesis |
| US4994071A (en) | 1989-05-22 | 1991-02-19 | Cordis Corporation | Bifurcating stent apparatus and method |
| US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
| AU7998091A (en) | 1990-05-17 | 1991-12-10 | Harbor Medical Devices, Inc. | Medical device polymer |
| JPH04230389A (en) | 1990-07-16 | 1992-08-19 | American Home Prod Corp | Rapamycin derivative |
| US5023262A (en) | 1990-08-14 | 1991-06-11 | American Home Products Corporation | Hydrogenated rapamycin derivatives |
| PT98990A (en) | 1990-09-19 | 1992-08-31 | American Home Prod | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS OF RAPAMICIN |
| US5120842A (en) | 1991-04-01 | 1992-06-09 | American Home Products Corporation | Silyl ethers of rapamycin |
| US5120727A (en) | 1991-05-29 | 1992-06-09 | American Home Products Corporation | Rapamycin dimers |
| US5120725A (en) | 1991-05-29 | 1992-06-09 | American Home Products Corporation | Bicyclic rapamycins |
| US6090901A (en) | 1991-07-05 | 2000-07-18 | Biocompatibles Limited | Polymeric surface coatings |
| US5705583A (en) | 1991-07-05 | 1998-01-06 | Biocompatibles Limited | Polymeric surface coatings |
| US5163852A (en) | 1992-02-11 | 1992-11-17 | W. L. Gore & Associates, Inc. | Coaxial cable side tape connector assembly and processes for assembly |
| US5177203A (en) | 1992-03-05 | 1993-01-05 | American Home Products Corporation | Rapamycin 42-sulfonates and 42-(N-carboalkoxy) sulfamates useful as immunosuppressive agents |
| US5464650A (en) | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
| US5605696A (en) | 1995-03-30 | 1997-02-25 | Advanced Cardiovascular Systems, Inc. | Drug loaded polymeric material and method of manufacture |
| US5837313A (en) | 1995-04-19 | 1998-11-17 | Schneider (Usa) Inc | Drug release stent coating process |
| US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| CA2256323C (en) | 1997-03-31 | 2007-05-22 | Kabushikikaisha Igaki Iryo Sekkei | Stent for vessel |
| US20040213789A1 (en) * | 1997-09-02 | 2004-10-28 | Oron Yacoby-Zeevi | Heparanase activity neutralizing anti-heparanase monoclonal antibody and other anti-heparanase antibodies |
| US6419692B1 (en) | 1999-02-03 | 2002-07-16 | Scimed Life Systems, Inc. | Surface protection method for stents and balloon catheters for drug delivery |
| GB0100760D0 (en) | 2001-01-11 | 2001-02-21 | Biocompatibles Ltd | Drug delivery from stents |
| US7708712B2 (en) * | 2001-09-04 | 2010-05-04 | Broncus Technologies, Inc. | Methods and devices for maintaining patency of surgically created channels in a body organ |
| KR20060052722A (en) * | 2003-08-05 | 2006-05-19 | 가부시키가이샤 가네카 | Bio-attracting stent |
| JP4379044B2 (en) * | 2003-08-22 | 2009-12-09 | 株式会社カネカ | Indwelling stent |
| JP2008506507A (en) * | 2004-07-19 | 2008-03-06 | ブロンカス テクノロジーズ, インコーポレイテッド | Method and instrument for maintaining a surgically created channel in a body organ |
-
2006
- 2006-03-22 WO PCT/US2006/010700 patent/WO2007032777A2/en not_active Ceased
- 2006-03-22 EP EP16171630.3A patent/EP3138531A1/en not_active Withdrawn
- 2006-03-22 EP EP06739478A patent/EP1877004A4/en not_active Ceased
- 2006-03-22 JP JP2008503210A patent/JP5242374B2/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001087372A1 (en) * | 2000-05-12 | 2001-11-22 | Cordis Corporation | Drug combinations useful for prevention of restenosis |
| WO2002062335A2 (en) * | 2001-01-16 | 2002-08-15 | Vascular Therapies, Llc | Implantable device containing resorbable matrix material and anti-proliferative drugs for preventing or treating failure of hemodialysis vascular access and other vascular grafts |
| WO2003022807A2 (en) * | 2001-09-10 | 2003-03-20 | Abbott Laboratories | Medical devices containing rapamycin analogs |
| WO2004022124A1 (en) * | 2002-09-06 | 2004-03-18 | Abbott Laboratories | Medical device having hydration inhibitor |
| WO2005092406A1 (en) * | 2004-03-22 | 2005-10-06 | Advanced Cardiovascular Systems, Inc. | Phosphoryl choline coating compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5242374B2 (en) | 2013-07-24 |
| JP2008534074A (en) | 2008-08-28 |
| EP3138531A1 (en) | 2017-03-08 |
| WO2007032777A2 (en) | 2007-03-22 |
| EP1877004A2 (en) | 2008-01-16 |
| WO2007032777A3 (en) | 2007-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20071022 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
| AX | Request for extension of the european patent |
Extension state: AL BA HR MK YU |
|
| DAX | Request for extension of the european patent (deleted) | ||
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20111228 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61F 2/00 20060101AFI20111221BHEP Ipc: A61K 31/44 20060101ALI20111221BHEP Ipc: A61L 31/16 20060101ALI20111221BHEP |
|
| 17Q | First examination report despatched |
Effective date: 20130327 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R003 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
| 18R | Application refused |
Effective date: 20160924 |