EP1700853A4 - Processes for producing tetrahydropyran-4-one and pyran-4-one - Google Patents

Processes for producing tetrahydropyran-4-one and pyran-4-one

Info

Publication number
EP1700853A4
EP1700853A4 EP04807306A EP04807306A EP1700853A4 EP 1700853 A4 EP1700853 A4 EP 1700853A4 EP 04807306 A EP04807306 A EP 04807306A EP 04807306 A EP04807306 A EP 04807306A EP 1700853 A4 EP1700853 A4 EP 1700853A4
Authority
EP
European Patent Office
Prior art keywords
pyran
metal catalyst
processes
solvent
producing tetrahydropyran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04807306A
Other languages
German (de)
French (fr)
Japanese (ja)
Other versions
EP1700853A1 (en
Inventor
Shigeyoshi Nishino
Kenji Hirotsu
Hidetaka Shima
Shinobu Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ube Corp
Original Assignee
Ube Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries Ltd filed Critical Ube Industries Ltd
Publication of EP1700853A1 publication Critical patent/EP1700853A1/en
Publication of EP1700853A4 publication Critical patent/EP1700853A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/185—Saturated compounds containing keto groups bound to acyclic carbon atoms containing —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for producing tetrahydropyran-4-one, which is represented by the formula (1), characterized by reacting at least one of dihydropyran-4-one and pyran-4-one, which are represented by the formula (2): (2) (wherein (A) indicates a single bond or double bond), with hydrogen either (a) in a mixed solvent comprising an aprotic solvent and an alcohol solvent in the presence of a metal catalyst or (b) in a hydrophobic organic solvent in the presence of an anhydrous metal catalyst obtained by dehydrating a hydrous metal catalyst.
EP04807306A 2003-12-19 2004-12-17 Processes for producing tetrahydropyran-4-one and pyran-4-one Withdrawn EP1700853A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP2003422053 2003-12-19
JP2004110674 2004-04-05
JP2004110673 2004-04-05
JP2004118686 2004-04-14
JP2004140152 2004-05-10
JP2004198148 2004-07-05
PCT/JP2004/018949 WO2005061479A1 (en) 2003-12-19 2004-12-17 Processes for producing tetrahydropyran-4-one and pyran-4-one

Publications (2)

Publication Number Publication Date
EP1700853A1 EP1700853A1 (en) 2006-09-13
EP1700853A4 true EP1700853A4 (en) 2009-07-22

Family

ID=34714678

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04807306A Withdrawn EP1700853A4 (en) 2003-12-19 2004-12-17 Processes for producing tetrahydropyran-4-one and pyran-4-one

Country Status (5)

Country Link
US (1) US7745649B2 (en)
EP (1) EP1700853A4 (en)
JP (3) JP4687464B2 (en)
CN (2) CN102627621B (en)
WO (1) WO2005061479A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108586405A (en) * 2018-02-05 2018-09-28 南京法恩化学有限公司 A kind of preparation method of tetrahydro pyrone
CN108912081A (en) * 2018-06-18 2018-11-30 苏州盖德精细材料有限公司 A kind of synthetic method of medicine intermediate Tetrahydro-pyran-4-one
CN110229130A (en) * 2019-07-04 2019-09-13 海门华祥医药科技有限公司 The synthesis of tetrahydro pyrone and its derivative and process of preparing
CN114560835A (en) * 2020-11-27 2022-05-31 苏州艾缇克药物化学有限公司 Preparation method of tetrahydropyranone derivative

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1315630A (en) * 1971-03-31 1973-05-02 Beecham Group Ltd Penicillins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4729512U (en) 1971-04-30 1972-12-04
JPS59160538A (en) * 1983-03-03 1984-09-11 Nippon Pillar Packing Co Ltd Manufacture of catalyst
JPH0796549B2 (en) * 1987-01-09 1995-10-18 日産化学工業株式会社 Method for producing tetrahydropyran-3-ones
JP3563424B2 (en) * 1993-11-26 2004-09-08 塩野義製薬株式会社 Method for producing 4H-pyran-4-one
JP3867213B2 (en) * 1996-08-07 2007-01-10 豊玉香料株式会社 Method for producing ketoaldehyde
JP4123542B2 (en) * 1997-07-07 2008-07-23 住友化学株式会社 Method for producing pyrazolinone derivatives
JP4523275B2 (en) * 2001-11-08 2010-08-11 エボニック デグサ ゲーエムベーハー Supported catalysts for the hydrogenation of nitroaromatic compounds.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1315630A (en) * 1971-03-31 1973-05-02 Beecham Group Ltd Penicillins

Also Published As

Publication number Publication date
JP4687464B2 (en) 2011-05-25
US20070078272A1 (en) 2007-04-05
JP2013227322A (en) 2013-11-07
JP2011121951A (en) 2011-06-23
CN102627621A (en) 2012-08-08
EP1700853A1 (en) 2006-09-13
CN1898229A (en) 2007-01-17
US7745649B2 (en) 2010-06-29
CN1898229B (en) 2012-05-30
WO2005061479A1 (en) 2005-07-07
JP5338798B2 (en) 2013-11-13
JPWO2005061479A1 (en) 2007-12-13
CN102627621B (en) 2015-05-27
JP5724119B2 (en) 2015-05-27

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