EP1611147A4 - 6"-amino-6"-deoxygalactosylceramides - Google Patents

6"-amino-6"-deoxygalactosylceramides

Info

Publication number
EP1611147A4
EP1611147A4 EP03816701A EP03816701A EP1611147A4 EP 1611147 A4 EP1611147 A4 EP 1611147A4 EP 03816701 A EP03816701 A EP 03816701A EP 03816701 A EP03816701 A EP 03816701A EP 1611147 A4 EP1611147 A4 EP 1611147A4
Authority
EP
European Patent Office
Prior art keywords
deoxygalactosylceramides
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03816701A
Other languages
German (de)
French (fr)
Other versions
EP1611147A1 (en
Inventor
Paul B Savage
Albert Bendelac
Luc Teyton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham Young University
Original Assignee
Brigham Young University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham Young University filed Critical Brigham Young University
Publication of EP1611147A1 publication Critical patent/EP1611147A1/en
Publication of EP1611147A4 publication Critical patent/EP1611147A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP03816701A 2003-03-20 2003-03-20 6"-amino-6"-deoxygalactosylceramides Withdrawn EP1611147A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/008530 WO2004094444A1 (en) 2003-03-20 2003-03-20 6'-amino-6'-deoxygalactosylceramides

Publications (2)

Publication Number Publication Date
EP1611147A1 EP1611147A1 (en) 2006-01-04
EP1611147A4 true EP1611147A4 (en) 2007-10-17

Family

ID=33308974

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03816701A Withdrawn EP1611147A4 (en) 2003-03-20 2003-03-20 6"-amino-6"-deoxygalactosylceramides

Country Status (4)

Country Link
EP (1) EP1611147A4 (en)
AU (1) AU2003225891A1 (en)
CA (1) CA2519568C (en)
WO (1) WO2004094444A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7419958B2 (en) 2001-03-26 2008-09-02 Dana-Farber Cancer Institute, Inc. Method of attenuating reactions to skin irritants
US7645873B2 (en) 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
WO2006060117A2 (en) 2004-11-02 2006-06-08 The Board Of Trustees Of The Leland Stanford Junior University Methods for inhibition of nkt cells
DK1848813T3 (en) 2005-01-28 2013-07-15 Univ Brigham Young Activation of bacterial glycolipid from CD1D-restricted NKT cells
US8227581B2 (en) * 2006-04-07 2012-07-24 The Scripps Research Institute Modified α-galactosyl ceramides for staining and stimulating natural killer T cells
WO2008005824A1 (en) 2006-06-30 2008-01-10 The Scripps Research Institute Adjuvants and methods of use
US8916164B2 (en) 2007-08-29 2014-12-23 Abivax Methods of enhancing adjuvaticity of vaccine compositions
EP2058011A1 (en) * 2007-11-07 2009-05-13 Wittycell Nkt cell activating gycolipids covalently bound antigens and/or drug
EP2060252A1 (en) 2007-11-19 2009-05-20 Wittycell New formulation of galactosylceramide derivatives
US9220767B2 (en) 2008-10-08 2015-12-29 Abivax Vaccine composition for use against influenza
EP2842961B1 (en) 2012-04-26 2016-12-14 Riken New carbamate glycolipid and use thereof
US9321796B2 (en) 2012-06-28 2016-04-26 Universiteit Gent Galactopyranosyl derivatives useful as medicaments
KR102162619B1 (en) 2012-07-26 2020-10-08 빅토리아 링크 엘티디 Organic compounds
CN105008380B (en) * 2012-12-06 2018-01-23 维多利亚联结有限公司 Conjugate compound
WO2015187040A1 (en) * 2014-06-05 2015-12-10 Regan James Anderson Amino sphingoglycolipid analogues

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
TW261533B (en) * 1992-07-16 1995-11-01 Kirin Brewery

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZHOU X-T ET AL: "Synthesis and NKT Cell Stimulating Properties of Fluorophore- and Biotin-Appended 6-Amino-6-deoxy-galactosylceramides", ORGANIC LETTERS, ACS, WASHINGTON, DC, US, vol. 4, no. 8, March 2002 (2002-03-01), pages 1267 - 1270, XP003008968, ISSN: 1523-7060 *

Also Published As

Publication number Publication date
CA2519568A1 (en) 2004-11-04
EP1611147A1 (en) 2006-01-04
WO2004094444A1 (en) 2004-11-04
AU2003225891A1 (en) 2004-11-19
CA2519568C (en) 2012-01-03

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20051020

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20070917

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 37/04 20060101ALI20070911BHEP

Ipc: C07H 15/18 20060101ALI20070911BHEP

Ipc: C07H 15/04 20060101ALI20070911BHEP

Ipc: A61K 31/7032 20060101AFI20070911BHEP

17Q First examination report despatched

Effective date: 20071129

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20080410