EP1572271A1 - Auto-injector comprising a resettable releasing safety device - Google Patents

Auto-injector comprising a resettable releasing safety device

Info

Publication number
EP1572271A1
EP1572271A1 EP20030811707 EP03811707A EP1572271A1 EP 1572271 A1 EP1572271 A1 EP 1572271A1 EP 20030811707 EP20030811707 EP 20030811707 EP 03811707 A EP03811707 A EP 03811707A EP 1572271 A1 EP1572271 A1 EP 1572271A1
Authority
EP
European Patent Office
Prior art keywords
means
auto
position
characterized
injector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20030811707
Other languages
German (de)
French (fr)
Inventor
Benjamin Scherer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TecPharma Licensing AG
Original Assignee
TecPharma Licensing AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH198702 priority Critical
Priority to CH19872002 priority
Application filed by TecPharma Licensing AG filed Critical TecPharma Licensing AG
Priority to PCT/CH2003/000758 priority patent/WO2004047893A1/en
Publication of EP1572271A1 publication Critical patent/EP1572271A1/en
Application status is Withdrawn legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033Spring-loaded one-shot injectors with or without automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206With automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566Means improving security or handling thereof
    • A61M5/3157Means providing feedback signals when administration is completed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps

Abstract

Disclosed is a syringe (50) which can be displaced within a housing (14, 16) by means of the power exercised by springs (7, 9, 11). Transducing means (4, 5) transduce said spring power to the syringe (50) while resilient stopping cams (31) which engage into a groove (32) of the transducing means (4, 5) maintain the transducing means (4, 5) in the initial position thereof until being released. In order to prepare an injection, an axially displaceable releasing head (13) is pulled back from the represented position into a position in which the safety device of the auto-injector is released. In order to trigger an injection, the releasing head (13) is moved forward, resilient tongues that are disposed on the releasing head (13) engaging with the stopping cams (31) so as to push said stopping cams (31) apart. Resetting buttons (62) which are disposed inside the releasing head (13) act upon the resilient tongues when being pressed such that the resilient tongues do not engage with the stopping cams (31) when the releasing head is moved forward.

Description

Autoinjector with resettable fuse tripping

The application relates to an automatic injector for automatically injecting an active ingredient, having a container for the active ingredient, the purpose of piercing the injection needle in a housing is displaceable together with a connected thereto injection needle by spring force, with a syringe piston, the purpose of Ausschüttens of the active ingredient in the container by spring force slidable, with transmission means that transmit the spring force to the container and / or the syringe plunger, with holding means to hold the transmission means and with release means, sen to veranlas- the holding means to release the transmission means when the trigger means from a first to a second position be brought.

Auto-injectors of the aforementioned type are known in many versions. The information contained herein for administration of drugs that the patient concerned injected himself. Many of the known injectors Autoin- have a safety yoke, which is to avoid accidentally an injection process is triggered. These trip fuses are mostly components that prevent the release means from being operated. These components are formed, for example, as sliders, which are movable with respect to the release agent or they are formed as a lid or plug which must be removed prior to injection. Of course, these additional components increase the cost of production of the well-known auto-injectors and make their use difficult.

It is therefore an object of the present invention to provide an auto-injector of the type mentioned in which the release means do without additional control elements and which can be secured again also without triggering an injection, after it has been unlocked.

This object is inventively achieved in that operable resetting means are provided which make it possible to bring the actuating means from the first to the second position without causing the transmission means to be released. In this inventive solution, the safety catch is effected by the release means from the second position are brought into the first position. Starting from this first position, an injection can now be triggered by the trigger means is moved to the second position. On the other hand, the release means can be returned from the first position to the second position back by operation of the return means without triggering of an injection. The inventive auto-injector has relatively few components and is particularly simple and safe in operation.

According to one embodiment of the invention the holding means are designed as resilient cams, which engage with their free ends in a recess provided on the transmission means. The triggering means may comprise resilient tongues, which engage the resilient cam and bring it from its engagement in the groove when the trigger means is moved from the first to the second position. These measures allow a particularly simple design and the resilient cam and the resilient tongues can be manufactured as plastic parts by injection molding. This makes it possible to form the return means so according to a further embodiment of the invention, that the resilient tongues are elastically deformed by their actuation in such a way that they do not engage the resilient cam when the release means are brought from the first to the second position ,

According to a preferred embodiment of the invention, the release means comprise a release head, which is disposed axially displaceable relative to the housing. This allows a particularly simple operation of the automatic injector with only one hand. When the firing head in its first position with respect to the housing is further back than in its second position, it can be pressed to initiate forward, which favors the correct posture of the automatic injector on the skin of the patient. In addition, when the tripping head on the side remote from the injection needle, the rear end of the housing is arranged, the operation is further facilitated because the user touched for initiating the injection then either on the circumference of the actuator head, or may press on the rear end side. According to another embodiment of the invention, spring means are provided which bias the firing head in the direction towards its second position. This not only favors the initiation or reset to the lock position, but also ensures that the release means according to injection, will remain in the second position. Advantageously, the return means comprise at least one push button received in the firing head and substantially radially actuated to the longitudinal axis of the autoinjector. Thus, the firing head can be easily performed with pushed push button from the first to the second, secured position.

An embodiment of the present invention is explained below by way of example with reference to the accompanying closer drawing. It shows:

1 shows a longitudinal section through an embodiment of an automatic injector according to Inventions in the charged state,

2 shows a longitudinal section through the auto-injector in interlocks defeated state, the sectional plane is rotated with respect to Figure 1 through 90 °,

3 shows a longitudinal section through the automatic injector after the insertion of the injection needle, said section being taken through the same plane as in figure 2,

4 shows a longitudinal section through the rear part of the automatic injector in the same operating position as shown in Figure 3, the section being led through the same plane as in Figure 1, and

5 shows a cross section along the line V - V in Figure 4 in relation to the Figure 4 on an enlarged scale.

The autoinjector consists of two main components, namely the

Reservoir portion shown in Figures 1 to 3 on the left, which receives a filled syringe 50 and the power pack, illustrated in the mentioned figures, the right, in which the 50 parts of this docu- ment for automatically piercing and pouring out of the syringe are housed. The two main components are releasably connected together by a bayonet-type connection between a receiving sleeve 16 and a power-sleeve. 1 In the following description the side of the autoinjector to which the injection needle is called the front is.

Based on FIG 1, showing the operative auto-injector, the power pack will now be described first. The parts for the drive of the auto-injector are received in the grip sleeve 14, a display window adjoins the rear end of the 51st The display window 51 is made like or translucent material fabricated from transparent or has openings, for example in the form of slots which make it possible to observe the display slidably received in the display window 51 12 from outside. The display 12 is preferably ring-shaped and characterized visible around the autoinjector from any direction. At the rear end of the autoinjector of the operating head 13 is arranged, which is provided on its rear end side with a cover 15 °. Within the grip sleeve 14, the sleeve 1 is accommodated power. At its rear end the power sleeve 1 is connected by means of a snap connection with a grid sleeve. 8 The raster sleeve 8 in turn accommodates a spring sleeve 10 slidably in their interior. The spring sleeve 10 is coupled to the rear by a snap-connection with the display 12th On the front side of the spring sleeve 10 of the transmission member 5 is slidably mounted in the power sleeve. 1 The transmission part 5 has the function of actuating the piston rod 52 of the syringe 50 to pour the contents of the syringe, as will be described in detail later. Within the spring sleeve 10, a spring is received in a tensioned state 9, the front is supported on the spring sleeve 10 and rear sleeve presses against the grid. 8 A second spring 11 is also in a tensioned state on the outer side of the spring sleeve 10 and supports the front of the transmission part 5 and presses back against the spring sleeve 10 degrees.

A designated as a piston guide 4 part lies with its front sleeve-shaped end of the collar of the syringe to and extends through the transmission part 5, the spring sleeve 10 and the grid sleeve 8 passes into the region of the actuating head 13. The piston guide 4 is formed by a spring 7 forward biased, which is supported at the rear of the screen sleeve. 8 At its rear end the piston guide 4 is held by two integrally formed on the grid sleeve 8 locking cams 31 which engage 4 integrally formed groove 32 in a rear end of the piston guide, in the embodiment shown in Figure 1 position. Latching members, for example balls 6, which are accommodated in radial apertures 33 of the piston guide 4 and engage in recesses 34 in the transmission part 5, provide in this operating position, that the transfer part 5 and the piston guide 4 can only move together. Of course, the catch members could also have another shape, for example, who bolts.

There now follows the description of the reservoir section. The parts for receiving the syringe 50 as mentioned in the receiving sleeve 16 housed, which is connectable to the power sleeve 1 as described. A sliding sleeve 21 receives the syringe with the interposition of a needle holder 22 in itself. The needle holder 22 prevents Luerslip couplings, that the injection needle 37 can be withdrawn from the syringe as long as the latter is in the autoinjector. The needle holder 22 is at the front on to a connected to the sliding sleeve 21 support ring 24th In syringes and needles having luer lock couplings, ie in which the injection needle is connected by means of a thread to the syringe, no needle holder 22 is present. The sliding sleeve 21 is slidable inside the receiving sleeve 16 and is urged by a spring 20 into the position shown in Figure 1 operating position. A sleeve-like needle guard 17 is slidably received within the receiving sleeve sixteenth The needle guard 17 is forward verschlössen by a snap-on lid 23, which leaves a passage for the needle-free and has at its rear end an inwardly directed flange 35. A spring 18 is supported at the front on the snap cover 23 and the rear of a driving ring 19 from. The spring 18 is located in this figure in its relaxed state.

In preparation for the injection of the autoinjector must be brought from the one shown in Figure 1 secured state to the unlocked state shown in FIG. 2 To this end, the actuation head 13 is moved to the rear. This can be achieved that the device supply head with one hand on the receiving sleeve 16 and with the other hand on the actuating taken 13 and the two parts are pulled apart. but due to the special design and arrangement of the actuating head 13, it is also possible to hold the autoinjector on the grip sleeve 14 and push with the thumb of the same hand the actuating head 13 to the rear. The actuating head 13 provided, circumferential ribs can thereby prevent a slide of the thumb. This rearward shifting of the actuation head 13 is hereinafter referred to as Entsicherungsbewegung. In this case, an area of ​​the display window 51 is at the front edge of the operating head 13 free on the inside of a striking, for example, red colored warning becomes visible sleeve 53, which clearly indicates that the auto-injector is now unlocked and ready for injection. slide during Entsicherungsbewegung to tabs 36, which are integrally formed on the inside of the cover disc 15 of the operating head 13, on the molded on the grid sleeve locking cam 31. The tongues and the locking cams are shaped so that radially resiliently in the Entsicherungsbewegung the tongues 36 yield, while sliding over the ends of the locking cams 31, which hold the piston guide 4 by engaging in the said grooves 32nd After the Entsicherungsbewegung formed on the actuating head 13 tongues are 36 like wedges between the locking cam 31. The shape of the tabs 36 can be seen particularly clearly in FIG. 4 urging with the Entsicherungsbewegung a spring 3 is stretched on said grid sleeve 8 molded hooks and a fastened in the actuating head with a snap connection retaining member 60 acts between, so the actuating head in its starting position according to FIG 1 and so ensures that the tongues 36 with slight applied bias to the latching cam 31st The auto-injector is now ready for injection and is set to the snap-on lid 23 at the desired location on the patient's skin. The patient holds the auto-injector on the grip sleeve 14th To trigger the injection now only the operating head 13 must be moved towards the front, ie towards the body of the patient.

In this release movement the tongues 36 penetrate between the

Latching cams 31 and spread them radially apart, whereby the piston guide 4 is released and pushed by the force of the spring 7 to the front. The piercing movement is also supported by the force of the springs 9 and 11, which act on the transmission part. 5 Since the transmission part 5 is connected by the balls 6 with the piston guide 4, a spring system, consisting of the springs 7, 9 and 11 is formed with a relatively high initial force, which contributes to the fact that the injection needle is safely advanced to the full depth of penetration. The force of the springs is transmitted through the slotted sleeve-shaped front end 4 'of the piston guide 4 onto the collar of the syringe 50, and pushes it along with the sliding sleeve 21, in which it is received, to the front, so that the injection needle is advanced 37 and the penetrates the patient's skin. During this movement, the sliding sleeve 21 presses both the spring 20 and - on the driving ring 19 - the spring 18 together. The insertion stroke is limited by engagement of shoulder 40 of the piston guide 4 at an inner shoulder 41 of the power sleeve. 1 In this end position, the openings 33 are aligned in the piston guide 4, which accommodate the balls 6, with depressions 42 which are provided in the power sleeve 1, the balls 6 can deflect outwards and the coupling between the piston guide 4 and the transmission part 5 is canceled. Simultaneously, the piston guide 4 is locked against the power sleeve 1 is now such that the force of the spring is received by the power sleeve 20 and therefore does not counteract the force of the spring. 7 Thus, now begin the injection automatically by the piston rod 52 of the syringe through the transmission part 5 under the force of the springs 11 and 9 further pushed forward. Simultaneously with the piercing movement, the spring 18 is tensioned by the moving through the sliding sleeve 21 in the figures to the left driving ring 19th

3 shows the auto-injector in the just-described operating condition. The needle 37 is fully extended, while the drug is still in the syringe 50th Starting from the operating condition shown in Figure 3 is now automatically pouring the drug. The balls 6 indicate the transmission part 5 freely, so that this shift in the piston guide 4 in and can thereby actuate the piston rod 52 of the syringe. the spring is sleeve 10 by successively releasing the springs 11 and 9 and displaced with it, the display 12 forward so that the indicator 12 reaches its end position when the piston rod 52 in the syringe 50 is fully forward, and consequently, all in the syringe liquid present is distributed. So that the user is able to follow the course of the injection process and provides the basis of the display 12 that the entire contents of the syringe is distributed. Here, the path that traverses the display 12, regardless of the stroke of the piston rod 52 of the syringe 50 and can be substantially smaller than the stroke of the transfer member 5. Thus, on the one hand avoided that the auto-injector is unnecessarily long and the other part can with him syringes with different strokes are used. This construction also has, which is thus carried out the additional advantage that the relatively high initial force of the springs 9 and 11 used for the piercing process and subsequently their relatively low end force is used for the injection process desirably slower.

When the sliding sleeve 21 provided spring tongues 38 are on

The beginning of the Einstechhubes prevented by a circumferential, inwardly projecting shoulder 39 of the receiving sleeve 16 from protruding outward. At the end of Einstechhubes the spring tongues protrude beyond the outer surface of the sliding sleeve 21 also. After the display 12 th the complete distributions of the drug has displayed, the user may withdraw the autoinjector. The spring 18, which was preloaded during the insertion process, ensures that the needle guard 17 remains during the retreat of the automatic injector in contact with the skin of the patient. Thus, the needle guard 17 relative to the receptacle pushes sleeve 16 forward until he onsnadel 37 completely covers the Injekti-. The spring tongues 38 snap behind the flange 35 of the needle guard 17 to the outside and prevent the latter can be pushed back into the receiving sleeve sixteenth Characterized any risk of accidental injury is eliminated by the injection needle.

the case can now arise that the user after the unlocking of the autoinjector not want to perform the injection, it was because he shrink from or be it that he is disturbed. It would be very dangerous to simply lay the auto-injector in interlocks defeated state aside. Therefore, means are provided in the inventive auto-injector, which make it possible to bring the unsecured auto-injector without triggering the injection back into the secured state. These means comprise reset buttons 62 with a tapered region 63 that protrude from opposite sides radially through the firing head 13 and extending between the tongues 36, as can be seen particularly clearly in FIG. 5 If these buttons pressed restoring 62, shifting the wedge-shaped regions 63 between the tabs 36 and spread them apart. the firing head can be pushed back 13 of the embodiment shown in Figure 2, unlocked position back into the secured position of Figure 1 now without an injection is initiated. This restoring movement in which the spread tongues on the locking cam 31 slide without pushing them apart, is supported by the force of the spring. 3 The reset buttons are radially guided slidably in the actuation head. 13 An elastic ring 64 that engages with pins 65 in corresponding holes of the reset buttons 62, holds the reset buttons 62 in position, as can be seen particularly clearly from FIG. 5 At the same time this resilient ring 64 also serves as a return spring for guiding the reset buttons 62 after pressing it in its initial position, as shown in FIG. 5 Upon actuation of the reset buttons 62, the elastic ring 64 deforms by the illustrated circular shape into an elliptical shape. In principle, the task of the provision could also be achieved with a single reset button, which would be tapered symmetrically in this case, so it would be pushed in operation like a wedge between the tongues 36th Ergonomically but two reset buttons 62 are more favorable because they can be pressed together, for example with the thumb and index finger, whereupon the tripping head 13 returns by the force of the spring 3 in the secured position.

Claims

claims
1. auto-injector for automatically injecting an active ingredient, having a container (50) for the active substance, which together with a connected thereto injection needle (37) for the purpose of piercing the injection needle (37) in an overall housing (14, 16) is displaceable by spring force , with a syringe plunger (52) which is for the purpose of Ausschüttens of the active substance in the reservoir (50) displaceable by spring force, with transmission means (4, 5) which transfer the spring force to the container (50) and / or the syringe plunger (52), with holding means (31) to the transfer means (4, 5) to hold and trigger means (13) to cause the holding means (31), the transmission means (4, 5) to release when the trigger means (13) from a first are brought into a second position, characterized in that operable return means (62) are provided which make it possible to bring the actuating means (13) from the first to the second position, without changing the Übertragungsm edium (4, 5) are released.
2. auto-injector according to claim 1, characterized in that the holding means are designed as resilient lugs (31) which engage with their free ends in a recess (32) provided on the transmission means (4, 5) is provided.
3. auto-injector according to claim 2, characterized in that
Trigger means (13) have resilient tongues (36) which attack on the resilient cam (31) and bring it from its engagement in the recess (32) when the triggering means (13) are brought from the first to the second position.
4. auto-injector according to claim 3, characterized in that
Return means (62) are formed so that the resilient tongues (36) are elastically deformed by their actuation in such a way that they attack not on the resilient cam (31) when the triggering means (13) from said first brought in the second position become.
5. comprise auto-injector according to any one of the preceding claims, characterized in that the triggering means includes a firing head (13) disposed in cover (14, 16) to the housing is disposed axially displaceable.
6. auto-injector according to claim 5, characterized in that the actuation head (13) in its first position relative to the housing (14, 16) is further back than in its second position.
7. auto-injector according to claim 5 or 6, characterized in that the actuation head (13) facing away from the injection needle (37), the rear end of the housing (14, 16) is arranged.
8. autoinjector according to one of claims 5 to 7, characterized in that spring means (3) are provided which bias the firing head (13) toward its second position.
9. have autoinjector according to one of claims 5 to 8, characterized in that the restoring means comprise at least a push button (62) received in the firing head (13) and is substantially radially actuated to the longitudinal axis of the autoinjector.
EP20030811707 2002-11-25 2003-11-17 Auto-injector comprising a resettable releasing safety device Withdrawn EP1572271A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CH198702 2002-11-25
CH19872002 2002-11-25
PCT/CH2003/000758 WO2004047893A1 (en) 2002-11-25 2003-11-17 Auto-injector comprising a resettable releasing safety device

Publications (1)

Publication Number Publication Date
EP1572271A1 true EP1572271A1 (en) 2005-09-14

Family

ID=32331829

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20030811707 Withdrawn EP1572271A1 (en) 2002-11-25 2003-11-17 Auto-injector comprising a resettable releasing safety device

Country Status (6)

Country Link
US (2) US7118553B2 (en)
EP (1) EP1572271A1 (en)
JP (1) JP2006507061A (en)
CN (1) CN100464796C (en)
AU (1) AU2003275895B2 (en)
WO (1) WO2004047893A1 (en)

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AU2003275895B2 (en) 2009-02-05
US20070142787A1 (en) 2007-06-21
US7635350B2 (en) 2009-12-22
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CN100464796C (en) 2009-03-04
US20050277885A1 (en) 2005-12-15

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