EP1429732A4 - A core formulation - Google Patents

A core formulation

Info

Publication number
EP1429732A4
EP1429732A4 EP01952575A EP01952575A EP1429732A4 EP 1429732 A4 EP1429732 A4 EP 1429732A4 EP 01952575 A EP01952575 A EP 01952575A EP 01952575 A EP01952575 A EP 01952575A EP 1429732 A4 EP1429732 A4 EP 1429732A4
Authority
EP
European Patent Office
Prior art keywords
core formulation
formulation
core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01952575A
Other languages
German (de)
French (fr)
Other versions
EP1429732A1 (en
Inventor
Akwete L Adjei
Yaping Zhu
Anthony J Cutie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kos Life Sciences Inc
Original Assignee
Kos Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kos Life Sciences Inc filed Critical Kos Life Sciences Inc
Priority to PCT/US2001/021676 priority Critical patent/WO2003005991A1/en
Publication of EP1429732A1 publication Critical patent/EP1429732A1/en
Publication of EP1429732A4 publication Critical patent/EP1429732A4/en
Application status is Withdrawn legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
EP01952575A 2001-07-10 2001-07-10 A core formulation Withdrawn EP1429732A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2001/021676 WO2003005991A1 (en) 2001-07-10 2001-07-10 A core formulation

Publications (2)

Publication Number Publication Date
EP1429732A1 EP1429732A1 (en) 2004-06-23
EP1429732A4 true EP1429732A4 (en) 2005-01-26

Family

ID=21742691

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01952575A Withdrawn EP1429732A4 (en) 2001-07-10 2001-07-10 A core formulation

Country Status (6)

Country Link
EP (1) EP1429732A4 (en)
JP (1) JP2004536841A (en)
AU (1) AU2001273310B2 (en)
CA (1) CA2453784A1 (en)
MX (1) MXPA04000176A (en)
WO (1) WO2003005991A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001273289B2 (en) * 2001-07-10 2004-10-07 Kos Life Sciences, Inc. Core formulation comprising pioglitazone hydrochloride and a biguanide
EP1429732A4 (en) * 2001-07-10 2005-01-26 Kos Life Sciences Inc A core formulation
US7785627B2 (en) * 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
WO2004069229A1 (en) * 2003-02-05 2004-08-19 Ipca Laboratories Limited Dual release anti-diabetic drugs and process of production thereof
WO2004091587A1 (en) * 2003-04-17 2004-10-28 Ipca Laboratories Limited Multiple release anti-diabetic drugs and process of production thereof
WO2005065663A1 (en) * 2003-12-31 2005-07-21 Alpharma, Inc. Rosiglitazone and metformin formulations
WO2010136847A1 (en) * 2009-05-26 2010-12-02 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Coated metformin with pioglitazone solution

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011049A (en) * 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
US6166043A (en) * 1995-06-20 2000-12-26 Takeda Chemical Industries, Ltd. Pharmaceutical composition
WO2001035940A2 (en) * 1999-11-16 2001-05-25 Smithkline Beecham P.L.C. Pharmaceutical composition comprising a thiazolidinedione-metformin hydrochloride
WO2001037808A1 (en) * 1999-11-23 2001-05-31 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
WO2001082875A2 (en) * 2000-05-01 2001-11-08 Aeropharm Technology, Inc. A core formulation
WO2003005995A1 (en) * 2001-07-10 2003-01-23 Aeropharm Technology Incorporated Core formulation comprising pioglitazone hydrochloride and a biguanide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356913A (en) * 1990-02-09 1994-10-18 The Upjohn Company Use of insulin sensitizing agents to treat hypertension
US6191162B1 (en) * 1998-05-28 2001-02-20 Medical Research Institute Method of reducing serum glucose levels
EP1429732A4 (en) * 2001-07-10 2005-01-26 Kos Life Sciences Inc A core formulation

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6166043A (en) * 1995-06-20 2000-12-26 Takeda Chemical Industries, Ltd. Pharmaceutical composition
US6011049A (en) * 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
WO2001035940A2 (en) * 1999-11-16 2001-05-25 Smithkline Beecham P.L.C. Pharmaceutical composition comprising a thiazolidinedione-metformin hydrochloride
WO2001037808A1 (en) * 1999-11-23 2001-05-31 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
WO2001082875A2 (en) * 2000-05-01 2001-11-08 Aeropharm Technology, Inc. A core formulation
WO2003005995A1 (en) * 2001-07-10 2003-01-23 Aeropharm Technology Incorporated Core formulation comprising pioglitazone hydrochloride and a biguanide

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DEASY P B ET AL: "COMBINED DIPYRIDAMOLE AND ASPIRIN PELLET FORMULATION FOR IMPROVED ORAL DRUG DELIVERY. PART 1: DEVELOPMENT PHARMACEUTICS", JOURNAL OF MICROENCAPSULATION, TAYLOR AND FRANCIS INC. LONDON, GB, vol. 13, no. 4, 1 July 1996 (1996-07-01), pages 385 - 394, XP000589902, ISSN: 0265-2048 *
See also references of WO03005991A1 *

Also Published As

Publication number Publication date
JP2004536841A (en) 2004-12-09
CA2453784A1 (en) 2003-01-23
AU2001273310B2 (en) 2004-10-07
MXPA04000176A (en) 2004-10-27
EP1429732A1 (en) 2004-06-23
WO2003005991A1 (en) 2003-01-23

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Legal Events

Date Code Title Description
AX Request for extension of the european patent to

Countries concerned: ALLTLVMKROSI

17P Request for examination filed

Effective date: 20040109

AK Designated contracting states:

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

RIC1 Classification (correction)

Ipc: 7A 61K 31/4439 B

Ipc: 7A 61K 31/155 B

Ipc: 7A 61K 9/16 A

Ipc: 7A 61K 9/50 B

A4 Despatch of supplementary search report

Effective date: 20041210

17Q First examination report

Effective date: 20050323

17Q First examination report

Effective date: 20050323

18D Deemed to be withdrawn

Effective date: 20070324