EP1408955A4 - Novel metallotexaphyrin derivatives - Google Patents

Novel metallotexaphyrin derivatives

Info

Publication number
EP1408955A4
EP1408955A4 EP01968223A EP01968223A EP1408955A4 EP 1408955 A4 EP1408955 A4 EP 1408955A4 EP 01968223 A EP01968223 A EP 01968223A EP 01968223 A EP01968223 A EP 01968223A EP 1408955 A4 EP1408955 A4 EP 1408955A4
Authority
EP
European Patent Office
Prior art keywords
metallotexaphyrin
derivatives
novel
novel metallotexaphyrin
metallotexaphyrin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01968223A
Other languages
German (de)
French (fr)
Other versions
EP1408955A1 (en
Inventor
Tarak D Mody
Joshua Galanter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacyclics LLC
Original Assignee
Pharmacyclics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacyclics LLC filed Critical Pharmacyclics LLC
Publication of EP1408955A1 publication Critical patent/EP1408955A1/en
Publication of EP1408955A4 publication Critical patent/EP1408955A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP01968223A 2000-08-30 2001-08-28 Novel metallotexaphyrin derivatives Withdrawn EP1408955A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22925500P 2000-08-30 2000-08-30
US229255P 2000-08-30
PCT/US2001/026885 WO2002017908A1 (en) 2000-08-30 2001-08-28 Novel metallotexaphyrin derivatives

Publications (2)

Publication Number Publication Date
EP1408955A1 EP1408955A1 (en) 2004-04-21
EP1408955A4 true EP1408955A4 (en) 2006-09-06

Family

ID=22860444

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01968223A Withdrawn EP1408955A4 (en) 2000-08-30 2001-08-28 Novel metallotexaphyrin derivatives

Country Status (4)

Country Link
EP (1) EP1408955A4 (en)
AU (1) AU2001288484A1 (en)
CA (1) CA2434744A1 (en)
WO (1) WO2002017908A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7449454B2 (en) 2000-08-30 2008-11-11 Pharmacyclics, Inc. Metallotexaphyrin derivatives
CA2434744A1 (en) * 2000-08-30 2002-03-07 Pharmacyclics, Inc. Novel metallotexaphyrin derivatives
US6919327B2 (en) * 2000-11-17 2005-07-19 Pharmacyclics, Inc. Texaphyrin coordination compounds and uses thereof
US20070072838A1 (en) 2005-09-26 2007-03-29 Pharmacyclics, Inc. High-purity texaphyrin metal complexes

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002017908A1 (en) * 2000-08-30 2002-03-07 Pharmacyclics, Inc. Novel metallotexaphyrin derivatives
WO2002039953A2 (en) * 2000-11-17 2002-05-23 Pharmacyclics, Inc. Texaphyrin coordination compounds and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935498A (en) * 1989-03-06 1990-06-19 Board Of Regents, The University Of Texas System Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
US5457183A (en) * 1989-03-06 1995-10-10 Board Of Regents, The University Of Texas System Hydroxylated texaphyrins
US5567687A (en) * 1989-03-06 1996-10-22 University Of Texas Texaphyrins and uses thereof
US5955586A (en) * 1996-03-22 1999-09-21 Sessler; Jonathan L. Highly boronated derivatives of texaphyrins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002017908A1 (en) * 2000-08-30 2002-03-07 Pharmacyclics, Inc. Novel metallotexaphyrin derivatives
WO2002039953A2 (en) * 2000-11-17 2002-05-23 Pharmacyclics, Inc. Texaphyrin coordination compounds and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; SYNYTSYA, ALLA ET AL: "Interaction of metallotexaphyrins with mono- and polysaccharides", XP002391134, retrieved from STN Database accession no. 2000:605280 *
JOURNAL OF THE CHEMICAL SOCIETY, PERKIN 2 , (9), 1876-1884, 2000, XP002391132 *
See also references of WO0217908A1 *

Also Published As

Publication number Publication date
AU2001288484A1 (en) 2002-03-13
EP1408955A1 (en) 2004-04-21
CA2434744A1 (en) 2002-03-07
WO2002017908A1 (en) 2002-03-07

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20030721

AK Designated contracting states

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Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/335 20060101ALI20060721BHEP

Ipc: A61P 35/00 20060101ALI20060721BHEP

Ipc: C07D 487/22 20060101AFI20060721BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20060808

17Q First examination report despatched

Effective date: 20070326

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20100302