EP1408924A1 - Stabilisierte ascorbinsäure, zusammensetzung und verwendungsverfahren - Google Patents
Stabilisierte ascorbinsäure, zusammensetzung und verwendungsverfahrenInfo
- Publication number
- EP1408924A1 EP1408924A1 EP00945153A EP00945153A EP1408924A1 EP 1408924 A1 EP1408924 A1 EP 1408924A1 EP 00945153 A EP00945153 A EP 00945153A EP 00945153 A EP00945153 A EP 00945153A EP 1408924 A1 EP1408924 A1 EP 1408924A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- composition
- vitamin
- particles
- coo
- wax
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
Definitions
- Fatty acids that are used in cosmetics formulations generally include at least stearic acid, oleic acid, myristic acid and palmitic acid.
- Other typical fatty acids include linoleic acid, behenic acid, and other common fatty acids of the general formula C n H 2n+] COOH.
- Confetti TM is advertised as having a good balance of structural integrity and rub-in characteristics, rubbing into the skin completely without any extra pressure.
- the Material Safety Data Sheets (MSDS) on Confetti TM products identifies them as containing a natural oil (e.g., coconut oil, tocopheryl acetate, retinyl palmitate), propylene glycol, synthetic beeswax, petrolatum, allantoin, PVM/MA Decadiene crosspolymer and benzophenone, as well as pigments and/or dyes.
- vitamin C and its derivatives in a composition that is both stable against environmental or ambient factors and that can be readily applied to the skin or hair of a subject.
- the vitamin C need not be and preferably is not soluble in the wax at the softening point or melting point of the wax).
- the vitamin C may be dispersed mechanically or dissolved or partially dissolved in a solvent and then recrystallized in the wax.
- the paniculate vitamin C must be present in the final product.
- Particles of the wax and stabilized vitamin C system are preferably provided with diameters between 200 and 2000 microns.
- the particles of the vitamin C itself is preferably particles of less than 10 microns, less than 8 microns, less than 5 microns and/or less than 3 or less than 1 microns (with dimensions down to about 0.1 microns or 0.5 microns).
- a preferred embodiment is the provision of the vitamin C in a wax comprising a unique product derived from jojoba oil.
- the jojoba ester and the vitamin C were added to a high speed propeller mixing apparatus and heated to about to at least 40 °C, using high speed propeller agitation. The mixing was continued for a short period of time until the vitamin C was dispersed in the melted ester. The melted ester was formed into particles (between about 200 and 2000 microns) with particles of vitamin C dispersed therein. This process provided the particles desired in the practice of the present invention. The particles would quickly soften when applied to the skin and spread over the surface of the skin with light finger or hand pressure.
- Example 2 The same example as Example 1 was repeated with a hydrocarbon wax with a melting point above 20 °C but below 60 °C. Similar mixing conditions were used and the final particulate product displayed similar results of spreading and softening upon application to the skin.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US349324 | 1989-05-08 | ||
US34932499A | 1999-07-08 | 1999-07-08 | |
PCT/US2000/018392 WO2001003664A1 (en) | 1999-07-08 | 2000-07-01 | Stabilized ascorbic acid, composition, and method of use |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1408924A1 true EP1408924A1 (de) | 2004-04-21 |
Family
ID=23371893
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00945153A Withdrawn EP1408924A1 (de) | 1999-07-08 | 2000-07-01 | Stabilisierte ascorbinsäure, zusammensetzung und verwendungsverfahren |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP1408924A1 (de) |
WO (1) | WO2001003664A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6436379B1 (en) * | 1997-10-17 | 2002-08-20 | International Flora Technologies Ltd. | Emollient for cuticle treatment and delivery system therefore |
CA2402009A1 (en) * | 2000-03-03 | 2001-09-13 | Australian Importers, Ltd. | Micronized vitamin c formulation |
US7101563B1 (en) | 2000-03-03 | 2006-09-05 | Australian Importers, Ltd. | Micronized vitamin C formulation |
US6706768B2 (en) * | 2002-03-21 | 2004-03-16 | International Flora Technologies, Ltd. | Production and use of novel alkoxylated monoesters |
US7304177B2 (en) * | 2003-10-10 | 2007-12-04 | International Flora Technologies, Ltd. | Method for improving spreading properties of cosmetic ingredients |
WO2008103926A1 (en) * | 2007-02-22 | 2008-08-28 | Innlabs, Llc | Vitamin c preparation |
JP4341983B2 (ja) * | 2007-12-07 | 2009-10-14 | 株式会社資生堂 | 皮膚外用剤 |
WO2012036743A1 (en) * | 2010-09-16 | 2012-03-22 | Kalamazoo Holdings, Inc. | Stable edible fluid fats and oils and improved ascorbic acid compositions to produce same |
KR20210000375A (ko) * | 2019-06-25 | 2021-01-05 | (주)아모레퍼시픽 | 무계면활성제형 화장료 조성물 |
KR102233930B1 (ko) | 2020-09-23 | 2021-03-30 | 주식회사 코리아나화장품 | 안정화된 아스코빅애씨드를 포함하는 화장료 조성물 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3247065A (en) * | 1963-10-14 | 1966-04-19 | Hoffmann La Roche | Free-flowing coated ascorbic acid |
US5589194A (en) * | 1993-09-20 | 1996-12-31 | Minnesota Mining And Manufacturing Company | Method of encapsulation and microcapsules produced thereby |
US5843411A (en) * | 1997-02-06 | 1998-12-01 | Topix Pharmaceuticals Inc. | Stabilization of ascorbic acid, ascorbic acid derivatives and/or extracts containing ascorbic acid for topical use |
-
2000
- 2000-07-01 EP EP00945153A patent/EP1408924A1/de not_active Withdrawn
- 2000-07-01 WO PCT/US2000/018392 patent/WO2001003664A1/en not_active Application Discontinuation
Non-Patent Citations (1)
Title |
---|
See references of WO0103664A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2001003664B1 (en) | 2001-08-09 |
WO2001003664A1 (en) | 2001-01-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020610 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20040203 |