EP1379869A4 - Method for therapeutically treating a clinically recognized form of cardiopathology in a living mammal - Google Patents

Method for therapeutically treating a clinically recognized form of cardiopathology in a living mammal

Info

Publication number
EP1379869A4
EP1379869A4 EP02753613A EP02753613A EP1379869A4 EP 1379869 A4 EP1379869 A4 EP 1379869A4 EP 02753613 A EP02753613 A EP 02753613A EP 02753613 A EP02753613 A EP 02753613A EP 1379869 A4 EP1379869 A4 EP 1379869A4
Authority
EP
European Patent Office
Prior art keywords
cardiopathology
therapeutically treating
living mammal
clinically recognized
recognized form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02753613A
Other languages
German (de)
French (fr)
Other versions
EP1379869A1 (en
Inventor
James P Morgan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
XIAO YONG FU
Original Assignee
XIAO YONG FU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by XIAO YONG FU filed Critical XIAO YONG FU
Publication of EP1379869A1 publication Critical patent/EP1379869A1/en
Publication of EP1379869A4 publication Critical patent/EP1379869A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027—New breeds of vertebrates
    • A01K67/0271—Chimeric animals, e.g. comprising exogenous cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
EP02753613A 2001-03-15 2002-03-14 Method for therapeutically treating a clinically recognized form of cardiopathology in a living mammal Withdrawn EP1379869A4 (en)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US27624401P 2001-03-15 2001-03-15
US27624301P 2001-03-15 2001-03-15
US27617501P 2001-03-15 2001-03-15
US27614701P 2001-03-15 2001-03-15
US27624701P 2001-03-15 2001-03-15
US27624501P 2001-03-15 2001-03-15
US27614801P 2001-03-15 2001-03-15
US27624601P 2001-03-15 2001-03-15
US276243P 2001-03-15
US276175P 2001-03-15
US276244P 2001-03-15
US276148P 2001-03-15
US276246P 2001-03-15
US276245P 2001-03-15
US276247P 2001-03-15
US276147P 2001-03-15
PCT/US2002/007555 WO2002075302A1 (en) 2001-03-15 2002-03-14 Method for therapeutically treating a clinically recognized form of cardiopathology in a living mammal

Publications (2)

Publication Number Publication Date
EP1379869A1 EP1379869A1 (en) 2004-01-14
EP1379869A4 true EP1379869A4 (en) 2004-08-11

Family

ID=27575321

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02753613A Withdrawn EP1379869A4 (en) 2001-03-15 2002-03-14 Method for therapeutically treating a clinically recognized form of cardiopathology in a living mammal

Country Status (4)

Country Link
EP (1) EP1379869A4 (en)
JP (1) JP2004532202A (en)
CA (1) CA2441289A1 (en)
WO (1) WO2002075302A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
US8105580B2 (en) 2001-12-07 2012-01-31 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to promote wound healing
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
EP1921133B1 (en) 2001-12-07 2015-05-20 Cytori Therapeutics, Inc. System for processing lipoaspirate cells
US20050095228A1 (en) 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
WO2006020322A2 (en) * 2004-07-19 2006-02-23 The Trustees Of Columbia University In The City Of New York Assay system for monitoring the effects of genetically engineered cells to alter function of a syncytium
CA2609361C (en) * 2005-05-25 2017-11-14 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
WO2010021993A1 (en) 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
AU2010242780B2 (en) 2009-05-01 2016-04-21 Puregraft Llc Systems, methods and compositions for optimizing tissue and cell enriched grafts
CA3012137A1 (en) * 2010-01-29 2011-08-04 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
JP5628131B2 (en) * 2011-10-19 2014-11-19 サイトリ セラピューティクス インコーポレイテッド Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
JP6247302B2 (en) * 2012-09-12 2017-12-13 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Identification of patients with abnormal fractional shortening
WO2021045190A1 (en) * 2019-09-05 2021-03-11 国立大学法人東北大学 Therapeutic agent for myocarditis
CN114176049B (en) * 2022-01-20 2023-01-31 河南农业大学 Method for simultaneously improving bee emergence rate and female worm number of indoor bred cotton bollworm tooth-lipped ichneumon fly

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942225A (en) * 1995-01-24 1999-08-24 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
WO2002009650A2 (en) * 2000-07-31 2002-02-07 New York Medical College Methods and compositions for the repair and/or regeneration of damaged myocardium
WO2002083864A2 (en) * 2001-04-13 2002-10-24 Anterogen Co., Ltd. Methods and reagents for cell transplantation
WO2003010303A1 (en) * 2001-07-24 2003-02-06 Es Cell International Pte Ltd Methods of inducing differentiation of stem cells

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942225A (en) * 1995-01-24 1999-08-24 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
WO2002009650A2 (en) * 2000-07-31 2002-02-07 New York Medical College Methods and compositions for the repair and/or regeneration of damaged myocardium
WO2002083864A2 (en) * 2001-04-13 2002-10-24 Anterogen Co., Ltd. Methods and reagents for cell transplantation
WO2003010303A1 (en) * 2001-07-24 2003-02-06 Es Cell International Pte Ltd Methods of inducing differentiation of stem cells

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
LEOR JONATHAN ET AL: "Gene transfer and cell transplant: An experimental approach to repair a 'broken heart'", CARDIOVASCULAR RESEARCH, vol. 35, no. 3, September 1997 (1997-09-01), pages 431 - 441, XP002284800, ISSN: 0008-6363 *
MARTIN BRADLEY J ET AL: "Human mesenchymal stem cells (hMSC) exhibit myogenic differentiation when implanted in infarcted rat myocardium", CIRCULATION, vol. 100, no. 18 SUPPL., 2 November 1999 (1999-11-02), 72nd Scientific Sessions of the American Heart Association;Atlanta, Georgia, USA; November 7-10, 1999, pages I.54, XP009032352, ISSN: 0009-7322 *
MIN JIANG-YONG ET AL: "Effects of co-transplantation of cultured human mesenchymal stem cells plus fetal cardiomyocytes on cardiac function in infarcted pigs", CIRCULATION, vol. 104, no. 17 Supplement, 23 October 2001 (2001-10-23), Scientific Sessions 2001 of the American Heart Association;Anaheim, California, USA; November 11-14, 2001, pages II.289, XP009032359, ISSN: 0009-7322 *
MIN JIANG-YONG ET AL: "Improvement of heart function in postinfarcted rats by transplantation of embryonic stem cells", CIRCULATION, vol. 102, no. 18 Supplement, 31 October 2000 (2000-10-31), Abstracts from American Heart Association Scientific Sessions 2000;New Orleans, Louisiana, USA; November 12-15, 2000, pages II.35, XP009032351, ISSN: 0009-7322 *
MIN JIANG-YONG ET AL: "Significant improvement of heart function by cotransplantation of human mesenchymal stem cells and fetal cardiomyocytes in postinfarcted pigs.", THE ANNALS OF THORACIC SURGERY. UNITED STATES NOV 2002, vol. 74, no. 5, November 2002 (2002-11-01), pages 1568 - 1575, XP002284801, ISSN: 0003-4975 *
ORLIC D ET AL: "TRANSPLANTED HEMATOPOIETIC STEM CELLS REPAIR MYOCARDIAL INFARCTS", BLOOD, W.B.SAUNDERS COMPAGNY, ORLANDO, FL, US, vol. 96, no. 11, PART 1, 16 November 2000 (2000-11-16), pages 221A, XP002907062, ISSN: 0006-4971 *
See also references of WO02075302A1 *
TOMITA S ET AL: "AUTOLOGOUS TRANSPLANTATION OF BONE MARROW CELLS IMPROVES DAMAGED HEART FUNCTION", CIRCULATION, AMERICAN HEART ASSOCIATION, DALLAS, TX, US, vol. 110, no. SUPPL 19, 9 November 1999 (1999-11-09), pages II - 247-II-256, XP000869909, ISSN: 0009-7322 *

Also Published As

Publication number Publication date
JP2004532202A (en) 2004-10-21
CA2441289A1 (en) 2002-09-26
EP1379869A1 (en) 2004-01-14
WO2002075302A8 (en) 2007-09-07
WO2002075302A1 (en) 2002-09-26

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