EP1294408A4 - Rhodamine diagnostic agent and diagnostic methods for detection of epithelial cancer - Google Patents

Rhodamine diagnostic agent and diagnostic methods for detection of epithelial cancer

Info

Publication number
EP1294408A4
EP1294408A4 EP00946949A EP00946949A EP1294408A4 EP 1294408 A4 EP1294408 A4 EP 1294408A4 EP 00946949 A EP00946949 A EP 00946949A EP 00946949 A EP00946949 A EP 00946949A EP 1294408 A4 EP1294408 A4 EP 1294408A4
Authority
EP
European Patent Office
Prior art keywords
diagnostic
rhodamine
detection
epithelial cancer
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00946949A
Other languages
German (de)
French (fr)
Other versions
EP1294408A1 (en
Inventor
Douglas D Burkett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zila Inc
Original Assignee
Zila Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zila Inc filed Critical Zila Inc
Publication of EP1294408A1 publication Critical patent/EP1294408A1/en
Publication of EP1294408A4 publication Critical patent/EP1294408A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0071—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form solution, solute

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Optics & Photonics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP00946949A 2000-06-30 2000-06-30 Rhodamine diagnostic agent and diagnostic methods for detection of epithelial cancer Withdrawn EP1294408A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/018126 WO2002002149A1 (en) 2000-06-30 2000-06-30 Rhodamine diagnostic agent and diagnostic methods for detection of epithelial cancer

Publications (2)

Publication Number Publication Date
EP1294408A1 EP1294408A1 (en) 2003-03-26
EP1294408A4 true EP1294408A4 (en) 2005-01-05

Family

ID=21741551

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00946949A Withdrawn EP1294408A4 (en) 2000-06-30 2000-06-30 Rhodamine diagnostic agent and diagnostic methods for detection of epithelial cancer

Country Status (11)

Country Link
EP (1) EP1294408A4 (en)
JP (1) JP2004501982A (en)
CN (1) CN1371290A (en)
AU (1) AU784558B2 (en)
BR (1) BR0013636A (en)
CA (1) CA2383697A1 (en)
IL (1) IL148341A0 (en)
MX (1) MXPA02002184A (en)
NO (1) NO20020958L (en)
NZ (1) NZ517445A (en)
WO (1) WO2002002149A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109768151B (en) * 2019-01-04 2020-05-08 浙江大学 Multi-color LED for illumination and display and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001064110A1 (en) * 2000-02-28 2001-09-07 Zila, Inc. Method for detecting and killing epithelial cancer cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0565668T3 (en) * 1991-10-31 2000-01-31 Zila Inc Biological dye composition, method of preparation thereof and for use in epithelial cancer signaling
US5618831A (en) * 1992-11-17 1997-04-08 Fuji Photo Film Co., Ltd. Composition and method for treating cancer
DE69630594T2 (en) * 1996-01-16 2004-09-23 Zila Inc., Phoenix METHOD AND MEANS FOR THE IN-VIVO DETECTION OF MOUTH-CREAM AND PRECACCESS STATES

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001064110A1 (en) * 2000-02-28 2001-09-07 Zila, Inc. Method for detecting and killing epithelial cancer cells

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO0202149A1 *
WILLHEIM, R. ET AL: "A preliminary study concerning the possibility of dietary carcinogenesis", GASTROENTEROLOGY , 23, 1-19 CODEN: GASTAB; ISSN: 0016-5085, 1953, XP008038362 *

Also Published As

Publication number Publication date
JP2004501982A (en) 2004-01-22
AU1675202A (en) 2002-01-14
NO20020958D0 (en) 2002-02-27
EP1294408A1 (en) 2003-03-26
NZ517445A (en) 2004-03-26
AU784558B2 (en) 2006-05-04
CN1371290A (en) 2002-09-25
MXPA02002184A (en) 2002-09-30
IL148341A0 (en) 2002-09-12
CA2383697A1 (en) 2002-01-10
BR0013636A (en) 2005-01-11
NO20020958L (en) 2002-04-24
WO2002002149A1 (en) 2002-01-10

Similar Documents

Publication Publication Date Title
AU3983201A (en) Compositions and methods for the early diagnosis of ovarian cancer
AU2001285020A1 (en) P97-active agent conjugates and their methods of use
EP1578347A4 (en) Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
HUP0203968A3 (en) Compositions and methods for the therapy and diagnosis of prostate cancer
PL366626A1 (en) Compositions and methods for the therapy and diagnosis of lung cancer
HK1059645A1 (en) X-ray measuring and testing complex
PL365244A1 (en) Compositions and methods for the therapy and diagnosis of breast cancer
EP1319178A4 (en) Method of identifying cancer markers and uses therefor in the diagnosis of cancer
AU4347701A (en) Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
IL151869A0 (en) Detection of immunological memory, t-cell conjugates for pathology imaging and therapy
AU2002246519A8 (en) Compositions and methods for the therapy and diagnosis of colon cancer
AU2002348297A8 (en) Proteonomic methods for diagnosis and monitoring of breast cancer
EP1212600A4 (en) Methylene blue diagnostic agent and diagnostic methods for detection of epithelial cancer
EP1268516A4 (en) Methods for detection and treatment of neural cancers
IL146141A0 (en) Method for detecting and killing epithelial cancer cells
AU2001243349A1 (en) Methods for the diagnosis and treatment of breast cancer
EP1349485A4 (en) Compositions and methods for the therapy and diagnosis of ovarian cancer
GB0110847D0 (en) Breast cancer detection
AU2599202A (en) Methods for comparitive analysis of carbohydrate polymers and carbohydrate polymers identified using same
PL366066A1 (en) Compositions and methods for the therapy and diagnosis of breast cancer
AU3483001A (en) Compositions and methods for the therapy and diagnosis of ovarian cancer
IL148341A0 (en) Rhodamine diagnostic agent and diagnostic methods for detection of epithelial cancer
AU2002327639A1 (en) Detection and treatment of cancers of breast
NO20021355D0 (en) Improved diagnostic method for the detection of dysplastic epithelial tissue
EP1259255A4 (en) Pai-2 conjugates for the treatment and imaging of cancer

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20020701

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Extension state: RO

RIN1 Information on inventor provided before grant (corrected)

Inventor name: BURKETT, DOUGLAS, D.

A4 Supplementary search report drawn up and despatched

Effective date: 20041122

17Q First examination report despatched

Effective date: 20060713

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20071205