EP1283675A4 - Methods of modulating the activity of mura - Google Patents

Methods of modulating the activity of mura

Info

Publication number
EP1283675A4
EP1283675A4 EP00936185A EP00936185A EP1283675A4 EP 1283675 A4 EP1283675 A4 EP 1283675A4 EP 00936185 A EP00936185 A EP 00936185A EP 00936185 A EP00936185 A EP 00936185A EP 1283675 A4 EP1283675 A4 EP 1283675A4
Authority
EP
European Patent Office
Prior art keywords
mura
modulating
activity
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00936185A
Other languages
German (de)
French (fr)
Other versions
EP1283675A1 (en
Inventor
Wensheng Du
Jianzhong Huang
Xinhe Jiang
Howard Kallender
Lynn Marie Mccloskey
David Payne
Shannon L Reed
Stephen F Rittenhouse
Horn Stephanie Van
Nicola G Wallis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
GlaxoSmithKline LLC
Original Assignee
SmithKline Beecham Ltd
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd, SmithKline Beecham Corp filed Critical SmithKline Beecham Ltd
Publication of EP1283675A1 publication Critical patent/EP1283675A1/en
Publication of EP1283675A4 publication Critical patent/EP1283675A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/315—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Streptococcus (G), e.g. Enterococci

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EP00936185A 2000-05-22 2000-05-22 Methods of modulating the activity of mura Withdrawn EP1283675A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/014079 WO2001089303A1 (en) 2000-05-22 2000-05-22 Methods of modulating the activity of mura

Publications (2)

Publication Number Publication Date
EP1283675A1 EP1283675A1 (en) 2003-02-19
EP1283675A4 true EP1283675A4 (en) 2009-08-26

Family

ID=21741410

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00936185A Withdrawn EP1283675A4 (en) 2000-05-22 2000-05-22 Methods of modulating the activity of mura

Country Status (3)

Country Link
EP (1) EP1283675A4 (en)
JP (1) JP2003533546A (en)
WO (1) WO2001089303A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4905417B2 (en) * 2007-07-10 2012-03-28 東レ株式会社 Method for producing cyclic polyarylene sulfide
US9199914B2 (en) * 2010-02-03 2015-12-01 Meh Associates, Inc. Multiple substituted fluoromethanes as selective and bioactive isosteres

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050020501A1 (en) * 2002-11-19 2005-01-27 Smithkline Beecham Corporation And Smithkline Beechm P.L.C. Methods of modulating the activity of mura

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5691161A (en) * 1996-08-01 1997-11-25 Eli Lilly And Company Peptidoglycan biosynthetic mura protein from Streptococcus pneumoniae
EP0890644A3 (en) * 1997-07-10 1999-09-29 Smithkline Beecham Corporation MurA gene from Staphylococcus aureus encoding DP-N-Acetylglucosamine enolpyruvyl transferase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050020501A1 (en) * 2002-11-19 2005-01-27 Smithkline Beecham Corporation And Smithkline Beechm P.L.C. Methods of modulating the activity of mura

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
D. CHEN ET AL: "Pathway screening: Novel technology for identifying inhibitors of MurA-F in a single incubation", ABSTRACTS OF THE INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 38, 1998, 38TH INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; SAN DIEGO, CALIFORNIA, USA; SEPTEMBER 24-27, 1998, pages 273, XP002536752 *
See also references of WO0189303A1 *

Also Published As

Publication number Publication date
EP1283675A1 (en) 2003-02-19
WO2001089303A1 (en) 2001-11-29
JP2003533546A (en) 2003-11-11

Similar Documents

Publication Publication Date Title
EP1323034A4 (en) Common application metamodel including c/c++ metamodel
ID28965A (en) AZABISIKLOALKANA AS CCR5 MODULATOR
HK1043369A1 (en) Compounds for the modulation of ppar-gamma activity
EP1311824A4 (en) Optically active substrates
IL154805A0 (en) System for the application of pesticides
FI20000863A (en) New treatment procedure
AU2002219229A1 (en) Means for the diagnosis and therapy of CTCL
GB2366677B (en) Optical amplitude modulator
GB0125451D0 (en) The backing up of data
GB0123379D0 (en) Modulators
AU7876900A (en) Antisense modulation of fra-1 expression
WO2004039773A8 (en) Coumpounds modulating the activity of gapdh and/or iamt
AU138705S (en) Bracelet
EP1283675A4 (en) Methods of modulating the activity of mura
AU8609201A (en) Reduction of the electrocardiographic ot interval
ZA200109120B (en) Use of Arylalkanoylpyridazines.
AU2001288238A1 (en) Methods of modulating activity of dxr
AU141167S (en) Bracelet
GB2372576B (en) Electro-Optic Modulator
GB2359181B (en) Educational aid
AU2001266932A1 (en) Human lyases
GB0026727D0 (en) Modulation of PDEII activity
GB0106338D0 (en) Electro-optic modulators
ZA9810837B (en) The use of brinzolamide to prevent visual field loss.
GB9920242D0 (en) Swab

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20021122

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20090723

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: SMITHKLINE BEECHAM PLC

Owner name: GLAXOSMITHKLINE LLC

18D Application deemed to be withdrawn

Effective date: 20091022