EP1137938A4 - Methods of screening for agonists and antagonists of the hdpxu17 receptor - Google Patents

Methods of screening for agonists and antagonists of the hdpxu17 receptor

Info

Publication number
EP1137938A4
EP1137938A4 EP99964135A EP99964135A EP1137938A4 EP 1137938 A4 EP1137938 A4 EP 1137938A4 EP 99964135 A EP99964135 A EP 99964135A EP 99964135 A EP99964135 A EP 99964135A EP 1137938 A4 EP1137938 A4 EP 1137938A4
Authority
EP
European Patent Office
Prior art keywords
hdpxu17
agonists
antagonists
receptor
screening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99964135A
Other languages
German (de)
French (fr)
Other versions
EP1137938A1 (en
Inventor
Derk J Bergsma
Wendy S Halsey
Ganesh Sathe
Da-Yuan Wang
Jeffrey S Culp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP1137938A1 publication Critical patent/EP1137938A1/en
Publication of EP1137938A4 publication Critical patent/EP1137938A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
EP99964135A 1998-12-08 1999-12-07 Methods of screening for agonists and antagonists of the hdpxu17 receptor Withdrawn EP1137938A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29749398A 1998-12-08 1998-12-08
US297493 1998-12-08
PCT/US1999/028941 WO2000034783A1 (en) 1998-12-08 1999-12-07 Methods of screening for agonists and antagonists of the hdpxu17 receptor

Publications (2)

Publication Number Publication Date
EP1137938A1 EP1137938A1 (en) 2001-10-04
EP1137938A4 true EP1137938A4 (en) 2003-03-19

Family

ID=23146550

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99964135A Withdrawn EP1137938A4 (en) 1998-12-08 1999-12-07 Methods of screening for agonists and antagonists of the hdpxu17 receptor

Country Status (2)

Country Link
EP (1) EP1137938A4 (en)
WO (1) WO2000034783A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ523523A (en) * 2000-07-07 2003-10-31 Univ North Carolina Method for screening candidate substances for ability to modulate P2Y receptor-mediated biological activity
JP4516273B2 (en) 2000-11-15 2010-08-04 ミナーヴァ・バイオテクノロジーズ・コーポレーション Oligonucleotide identifier
ATE481640T1 (en) 2000-11-27 2010-10-15 Minerva Biotechnologies Corp DIAGNOSTICS, DRUG SCREENING AND TREATMENT FOR CANCER
ATE469648T1 (en) 2001-09-05 2010-06-15 Minerva Biotechnologies Corp COMPOSITIONS AND USE THEREOF FOR TREATING CANCER
EP1660535A2 (en) 2002-11-27 2006-05-31 Minerva Biotechnologies Corporation Techniques and compositions for the diagnosis and treatment of cancer (muc1)
JP2012505636A (en) 2008-10-09 2012-03-08 ミネルバ バイオテクノロジーズ コーポレーション Methods for inducing pluripotency in cells
AU2010337836B2 (en) 2009-12-29 2014-03-06 Suven Life Sciences Limited Functional assay for G protein-coupled receptors
JP6895890B2 (en) 2015-02-10 2021-06-30 ミネルバ バイオテクノロジーズ コーポレーション Humanized anti-MUC1 * antibody

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999002675A1 (en) * 1997-07-09 1999-01-21 Euroscreen S.A. G-coupled receptor showing selective affinity for atp

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981223A (en) * 1998-01-20 1999-11-09 Smithkline Beecham Corporation HDPXU17 encodes a novel 7-transmembrane receptor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999002675A1 (en) * 1997-07-09 1999-01-21 Euroscreen S.A. G-coupled receptor showing selective affinity for atp

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0034783A1 *

Also Published As

Publication number Publication date
EP1137938A1 (en) 2001-10-04
WO2000034783A1 (en) 2000-06-15

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Legal Events

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Inventor name: CULP, JEFFREY, S.

Inventor name: WANG, DA-YUAN

Inventor name: SATHE, GANESH

Inventor name: HALSEY, WENDY, S.

Inventor name: BERGSMA, DERK, J.

A4 Supplementary search report drawn up and despatched

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