EP1060266A4 - Method for identifying mismatch repair glycosylase reactive sites, compound and uses thereof - Google Patents
Method for identifying mismatch repair glycosylase reactive sites, compound and uses thereofInfo
- Publication number
- EP1060266A4 EP1060266A4 EP99908354A EP99908354A EP1060266A4 EP 1060266 A4 EP1060266 A4 EP 1060266A4 EP 99908354 A EP99908354 A EP 99908354A EP 99908354 A EP99908354 A EP 99908354A EP 1060266 A4 EP1060266 A4 EP 1060266A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compound
- reactive sites
- mismatch repair
- identifying
- glycosylase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7554298P | 1998-02-23 | 1998-02-23 | |
US75542P | 1998-02-23 | ||
US09/224,227 US6174680B1 (en) | 1998-12-30 | 1998-12-30 | Method for identifying mismatch repair glycosylase reactive sites, compounds and uses thereof |
US224227 | 1998-12-30 | ||
PCT/US1999/003821 WO1999042622A1 (en) | 1998-02-23 | 1999-02-23 | Method for identifying mismatch repair glycosylase reactive sites, compound and uses thereof_____________________________________ |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1060266A1 EP1060266A1 (en) | 2000-12-20 |
EP1060266A4 true EP1060266A4 (en) | 2004-09-22 |
Family
ID=26756994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99908354A Withdrawn EP1060266A4 (en) | 1998-02-23 | 1999-02-23 | Method for identifying mismatch repair glycosylase reactive sites, compound and uses thereof |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1060266A4 (en) |
JP (1) | JP2002504352A (en) |
AU (1) | AU756384B2 (en) |
CA (1) | CA2321119A1 (en) |
WO (1) | WO1999042622A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000039345A1 (en) * | 1998-12-30 | 2000-07-06 | Dana-Farber Cancer Institute, Inc. | Mutation scanning array, and methods of use thereof |
FR2798138B1 (en) * | 1999-09-03 | 2004-05-21 | Centre Nat Rech Scient | CLONING, EXPRESSION AND CHARACTERIZATION OF THE SPG4 GENE RESPONSIBLE FOR THE MOST FREQUENT FORM OF AUTOSOME DOMINANT SPASTIC PARAPLEGIA |
US6365355B1 (en) * | 2000-03-28 | 2002-04-02 | The Regents Of The University Of California | Chimeric proteins for detection and quantitation of DNA mutations, DNA sequence variations, DNA damage and DNA mismatches |
CA2422487A1 (en) * | 2000-09-18 | 2002-03-28 | Pioneer Hi-Bred International, Inc. | Rice mlh1 ortholog and uses thereof |
WO2002030268A2 (en) * | 2000-10-13 | 2002-04-18 | Eos Biotechnology, Inc. | Methods of diagnosis of prostate cancer, compositions and methods of screening for modulators of prostate cancer |
US20050089852A1 (en) * | 2001-03-14 | 2005-04-28 | Lee Shao C. | Method and compositions for evaluating risk of developing type 2 diabetes in people of chinese descent |
DE10159904A1 (en) * | 2001-12-06 | 2003-07-03 | Adnagen Ag | Oligonucleotide arrangement, method for nucleotide detection and device therefor |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0122507A2 (en) * | 1983-03-23 | 1984-10-24 | Europäische Atomgemeinschaft (Euratom) | A process for directly determining apurinic and apyrimidinic sites in DNA |
WO1992007951A1 (en) * | 1990-10-19 | 1992-05-14 | Yoke Wah Kow | Quantitation of aldehyde-containing lesions in nucleic acids |
WO1997003210A1 (en) * | 1995-07-11 | 1997-01-30 | FORFÁS (trading as BIORESEARCH IRELAND) | Glycosylase mediated detection of nucleotide sequences at candidate loci |
US5719031A (en) * | 1996-08-14 | 1998-02-17 | Molecular Probes, Inc. | Dye labeled polymers as reagents for measuring polymer degradation |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5516663A (en) * | 1990-01-26 | 1996-05-14 | Abbott Laboratories | Ligase chain reaction with endonuclease IV correction and contamination control |
ATE176002T1 (en) * | 1990-07-24 | 1999-02-15 | Hoffmann La Roche | REDUCING NON-SPECIFIC AMPLIFICATION DURING (IN VITRO) NUCLEIC ACID AMPLIFICATION USING MODIFIED NUCLEIC ACID BASES |
-
1999
- 1999-02-23 AU AU27807/99A patent/AU756384B2/en not_active Ceased
- 1999-02-23 JP JP2000532560A patent/JP2002504352A/en not_active Withdrawn
- 1999-02-23 WO PCT/US1999/003821 patent/WO1999042622A1/en not_active Application Discontinuation
- 1999-02-23 CA CA002321119A patent/CA2321119A1/en not_active Abandoned
- 1999-02-23 EP EP99908354A patent/EP1060266A4/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0122507A2 (en) * | 1983-03-23 | 1984-10-24 | Europäische Atomgemeinschaft (Euratom) | A process for directly determining apurinic and apyrimidinic sites in DNA |
WO1992007951A1 (en) * | 1990-10-19 | 1992-05-14 | Yoke Wah Kow | Quantitation of aldehyde-containing lesions in nucleic acids |
WO1997003210A1 (en) * | 1995-07-11 | 1997-01-30 | FORFÁS (trading as BIORESEARCH IRELAND) | Glycosylase mediated detection of nucleotide sequences at candidate loci |
US5719031A (en) * | 1996-08-14 | 1998-02-17 | Molecular Probes, Inc. | Dye labeled polymers as reagents for measuring polymer degradation |
Non-Patent Citations (2)
Title |
---|
BOTURYN D ET AL: "Synthesis of Fluorescent Probes for the Detection of Abasic Sites in DNA", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 53, no. 15, 14 April 1997 (1997-04-14), pages 5485 - 5492, XP004105590, ISSN: 0040-4020 * |
See also references of WO9942622A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU2780799A (en) | 1999-09-06 |
WO1999042622A1 (en) | 1999-08-26 |
JP2002504352A (en) | 2002-02-12 |
CA2321119A1 (en) | 1999-08-26 |
AU756384B2 (en) | 2003-01-09 |
EP1060266A1 (en) | 2000-12-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20000918 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20040809 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20040831 |