EP1056413A4 - Injectable implants for tissue augmentation and restoration - Google Patents

Injectable implants for tissue augmentation and restoration

Info

Publication number
EP1056413A4
EP1056413A4 EP99908590A EP99908590A EP1056413A4 EP 1056413 A4 EP1056413 A4 EP 1056413A4 EP 99908590 A EP99908590 A EP 99908590A EP 99908590 A EP99908590 A EP 99908590A EP 1056413 A4 EP1056413 A4 EP 1056413A4
Authority
EP
European Patent Office
Prior art keywords
restoration
tissue augmentation
injectable implants
implants
injectable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99908590A
Other languages
German (de)
French (fr)
Other versions
EP1056413A1 (en
Inventor
Dan W Urry
Timothy M Parker
Paul A Glazer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioelastics Research Ltd
Original Assignee
Bioelastics Research Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US7629798P priority Critical
Priority to US76297P priority
Priority to US8715598P priority
Priority to US87155P priority
Application filed by Bioelastics Research Ltd filed Critical Bioelastics Research Ltd
Priority to PCT/US1999/004440 priority patent/WO1999043271A1/en
Publication of EP1056413A1 publication Critical patent/EP1056413A1/en
Publication of EP1056413A4 publication Critical patent/EP1056413A4/en
Application status is Withdrawn legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4601Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • A61F2002/30678Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/38Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs
EP99908590A 1998-02-27 1999-02-26 Injectable implants for tissue augmentation and restoration Withdrawn EP1056413A4 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US7629798P true 1998-02-27 1998-02-27
US76297P 1998-02-27
US8715598P true 1998-05-29 1998-05-29
US87155P 1998-05-29
PCT/US1999/004440 WO1999043271A1 (en) 1998-02-27 1999-02-26 Injectable implants for tissue augmentation and restoration

Publications (2)

Publication Number Publication Date
EP1056413A1 EP1056413A1 (en) 2000-12-06
EP1056413A4 true EP1056413A4 (en) 2003-08-20

Family

ID=26757929

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99908590A Withdrawn EP1056413A4 (en) 1998-02-27 1999-02-26 Injectable implants for tissue augmentation and restoration

Country Status (6)

Country Link
US (3) US6699294B2 (en)
EP (1) EP1056413A4 (en)
JP (1) JP2002507437A (en)
AU (1) AU2798599A (en)
CA (1) CA2319558A1 (en)
WO (1) WO1999043271A1 (en)

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US7192984B2 (en) * 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
EP1056413A4 (en) * 1998-02-27 2003-08-20 Bioelastics Res Ltd Injectable implants for tissue augmentation and restoration
US6662805B2 (en) * 1999-03-24 2003-12-16 The Johns Hopkins University Method for composite cell-based implants
WO2000056774A1 (en) * 1999-03-19 2000-09-28 Duke University Methods of using bioelastomers
DK1229940T3 (en) 1999-11-15 2014-08-18 Piramal Healthcare Canada Ltd Temperature-controlled pH-dependent and self-gelling aqueous biopolymeropløsning
DE60033055D1 (en) 1999-12-06 2007-03-08 Warsaw Orthopedic Inc Intervertebral disc treatment device
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
CA2412505C (en) 2000-06-29 2009-02-03 Caroline D. Hoemann Composition and method for the repair and regeneration of cartilage and other tissues
US6685626B2 (en) * 2001-02-02 2004-02-03 Regeneration Technologies, Inc. Compositions, devices, methods, and kits for induction of adhesions
US20070078435A1 (en) * 2001-06-14 2007-04-05 Corbett Stone Tissue augmentation methods using a medical injection apparatus
CA2487280A1 (en) * 2002-05-08 2003-11-20 The Regents Of The University Of California System and method for forming a substantially non-ablative cardiac conduction block
US7439067B2 (en) * 2002-05-20 2008-10-21 Battelle Memorial Institute Isolated polynucleotides and methods of promoting a morphology in a fungus
US20040054414A1 (en) 2002-09-18 2004-03-18 Trieu Hai H. Collagen-based materials and methods for augmenting intervertebral discs
KR101095771B1 (en) * 2002-09-18 2011-12-21 워쏘우 오르쏘페딕 인코포레이티드 Natural tissue devices and methods of implantation
US7744651B2 (en) * 2002-09-18 2010-06-29 Warsaw Orthopedic, Inc Compositions and methods for treating intervertebral discs with collagen-based materials
JP2006515765A (en) * 2002-11-15 2006-06-08 エスディージーアイ・ホールディングス・インコーポレーテッド Collagen-based materials and methods for the treatment of synovial joint
US7317950B2 (en) * 2002-11-16 2008-01-08 The Regents Of The University Of California Cardiac stimulation system with delivery of conductive agent
US20040106896A1 (en) * 2002-11-29 2004-06-03 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US20040186471A1 (en) * 2002-12-07 2004-09-23 Sdgi Holdings, Inc. Method and apparatus for intervertebral disc expansion
US7309359B2 (en) * 2003-08-21 2007-12-18 Warsaw Orthopedic, Inc. Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs
US7597660B2 (en) * 2003-09-19 2009-10-06 Broockeville Corporation B.V. Incontinence therapy
EP1516636A3 (en) * 2003-09-19 2005-08-03 Broockeville Corporation N.V. Use of a curable elastomer-precursor for a medical treatment
US20050113923A1 (en) * 2003-10-03 2005-05-26 David Acker Prosthetic spinal disc nucleus
US7053051B2 (en) * 2003-10-28 2006-05-30 Medtronic, Inc. Methods of preparing crosslinked materials and bioprosthetic devices
AU2005215213C1 (en) 2004-02-13 2011-04-28 Smith & Nephew Orthopaedics Ag Pharmaceutical composition comprising a fibrin matrix and dermal fibroblasts for the treatment of wounds
US8945223B2 (en) * 2004-03-12 2015-02-03 Warsaw Orthopedic, Inc. In-situ formable nucleus pulposus implant with water absorption and swelling capability
US20050209695A1 (en) * 2004-03-15 2005-09-22 De Vries Jan A Vertebroplasty method
AT510013T (en) * 2004-06-23 2011-06-15 Ca Nat Research Council Methods and uses of linker-containing polypeptide ligand
US7442389B2 (en) * 2004-08-20 2008-10-28 Artes Medical, Inc. Methods of administering microparticles combined with autologous body components
US7367961B2 (en) 2004-09-10 2008-05-06 Depuy Spine, Inc. Intradiscal injection of autologous interferon
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
WO2006078629A2 (en) * 2005-01-18 2006-07-27 Duke University In-situ crosslinkable elastin-like polypeptides for defect filling in cartilaginous tissue repair
GB0505202D0 (en) * 2005-03-14 2005-04-20 Intercytex Ltd Skin equivalent culture
US20060253199A1 (en) * 2005-05-03 2006-11-09 Disc Dynamics, Inc. Lordosis creating nucleus replacement method and apparatus
US20060253198A1 (en) * 2005-05-03 2006-11-09 Disc Dynamics, Inc. Multi-lumen mold for intervertebral prosthesis and method of using same
US20080199440A1 (en) 2005-05-26 2008-08-21 Mike Leek Tissue Repair Using Allogenic Dermal Fibroblasts
MX2007015363A (en) * 2005-06-16 2008-02-11 Artes Medical Inc Liquid crystal polymer syringes and containers and methods of use for long term storage of filler materials.
EP1896072A4 (en) * 2005-06-24 2013-01-09 Univ Duke A direct drug delivery system based on thermally responsive biopolymers
US20070102010A1 (en) * 2005-10-07 2007-05-10 Lemperle Stefan M Naso-pharyngeal tissue engineering
CN101384272B (en) 2005-12-20 2013-05-01 杜克大学 Methods and compositions for delivering active agents with enhanced pharmacological properties
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
US20080086200A1 (en) * 2006-01-03 2008-04-10 Heartcor Injectable implants for tissue augmentation and restoration
US7709227B2 (en) * 2006-01-04 2010-05-04 Phasebio Pharmaceuticals, Inc. Multimeric ELP fusion constructs
US8518105B2 (en) * 2006-03-24 2013-08-27 Abbott Cardiovascular System Inc. Methods and apparatuses for coating a lesion
US8092536B2 (en) * 2006-05-24 2012-01-10 Disc Dynamics, Inc. Retention structure for in situ formation of an intervertebral prosthesis
US20070276491A1 (en) * 2006-05-24 2007-11-29 Disc Dynamics, Inc. Mold assembly for intervertebral prosthesis
KR20070122316A (en) * 2006-06-26 2007-12-31 (주) 에스바이오메딕스 Soft tissue filler composition for injection and preparation method thereof
KR20070122315A (en) * 2006-06-26 2007-12-31 (주) 에스바이오메딕스 Soft tissue filler composition comprising autologous dermal cell and hyaluronic acid
US8399619B2 (en) 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US20080004703A1 (en) * 2006-06-30 2008-01-03 Warsaw Orthopedic, Inc. Method of treating a patient using a collagen material
US8118779B2 (en) 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
US20080004431A1 (en) * 2006-06-30 2008-01-03 Warsaw Orthopedic Inc Method of manufacturing an injectable collagen material
US20080097229A1 (en) * 2006-08-29 2008-04-24 Josee Roy Hygroscopic treatment for degenerating discs
BRPI0718615B1 (en) * 2006-11-13 2018-11-27 Elastagen Pty Ltd process for producing an elastic material from elastic material and tropoelastin
US20090036656A1 (en) * 2007-07-31 2009-02-05 Body Organ Biomedical Corp. Method for preparing a biomaterial
US20110212524A1 (en) * 2006-12-04 2011-09-01 Body Organ Biomedical Corporation Biomaterial and preparation method thereof
US20080177389A1 (en) * 2006-12-21 2008-07-24 Rob Gene Parrish Intervertebral disc spacer
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JP6157877B2 (en) * 2012-02-28 2017-07-05 三洋化成工業株式会社 The method of manufacturing the tissue regeneration gel, tissue regeneration protein solution and tissue regeneration gel
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WO1989010098A1 (en) * 1988-04-21 1989-11-02 Uab Research Foundation Stimulation of chemotaxis by chemotactic peptides
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See also references of WO9943271A1 *

Also Published As

Publication number Publication date
CA2319558A1 (en) 1999-09-02
AU2798599A (en) 1999-09-15
US6533819B1 (en) 2003-03-18
EP1056413A1 (en) 2000-12-06
US6699294B2 (en) 2004-03-02
JP2002507437A (en) 2002-03-12
US20020038150A1 (en) 2002-03-28
US20020116069A1 (en) 2002-08-22
WO1999043271A1 (en) 1999-09-02

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