EP0996742A4 - Methods for cleaving dna with nucleotide integrases - Google Patents

Methods for cleaving dna with nucleotide integrases

Info

Publication number
EP0996742A4
EP0996742A4 EP98908823A EP98908823A EP0996742A4 EP 0996742 A4 EP0996742 A4 EP 0996742A4 EP 98908823 A EP98908823 A EP 98908823A EP 98908823 A EP98908823 A EP 98908823A EP 0996742 A4 EP0996742 A4 EP 0996742A4
Authority
EP
European Patent Office
Prior art keywords
methods
cleaving dna
nucleotide integrases
integrases
nucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98908823A
Other languages
German (de)
French (fr)
Other versions
EP0996742A1 (en
Inventor
Alan M Lambowitz
Steve Zimmerly
Huatao Guo
Georg Mohr
Clifford J Beal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohio State University Research Foundation
Original Assignee
Ohio State University Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohio State University Research Foundation filed Critical Ohio State University Research Foundation
Priority claimed from PCT/US1998/003990 external-priority patent/WO1998038337A1/en
Publication of EP0996742A1 publication Critical patent/EP0996742A1/en
Publication of EP0996742A4 publication Critical patent/EP0996742A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP98908823A 1997-02-28 1998-02-27 Methods for cleaving dna with nucleotide integrases Withdrawn EP0996742A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3922097P 1997-02-28 1997-02-28
US39220P 1997-02-28
US7616198P 1998-02-26 1998-02-26
PCT/US1998/003990 WO1998038337A1 (en) 1997-02-28 1998-02-27 Methods for cleaving dna with nucleotide integrases
2001-06-11

Publications (2)

Publication Number Publication Date
EP0996742A1 EP0996742A1 (en) 2000-05-03
EP0996742A4 true EP0996742A4 (en) 2006-02-08

Family

ID=26715924

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98908823A Withdrawn EP0996742A4 (en) 1997-02-28 1998-02-27 Methods for cleaving dna with nucleotide integrases

Country Status (3)

Country Link
EP (1) EP0996742A4 (en)
AU (1) AU748237B2 (en)
CA (1) CA2282737A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001029059A1 (en) 1999-10-15 2001-04-26 The Ohio State University Research Foundation Methods for analyzing the insertion capabilities of modified group ii introns

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698421A (en) * 1995-09-12 1997-12-16 The Ohio State Research Foundation Ribonucleoprotein particles for cleaving double-stranded DNA and inserting an RNA/DNA molecule into the cleavage site

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
GUO H ET AL: "GROUP II INTRON ENDONUCLEASES USE BOTH RNA AND PROTEIN SUBUNITS FOR RECOGNITION OF SPECIFIC SEQUENCES IN DOUBLE-STRANDED DNA", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 16, no. 22, 1997, pages 6835 - 6848, XP002938492, ISSN: 0261-4189 *
MORAN J V ET AL: "Mobile Group II Introns of Yeast Mitochondrial DNA Are Novel Site-Specific Retroelements", MOLECULAR AND CELLULAR BIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, US, vol. 15, no. 5, May 1995 (1995-05-01), pages 2828 - 2838, XP002233947, ISSN: 0270-7306 *
See also references of WO9838337A1 *
YANG J ET AL: "EFFICIENT INTEGRATION OF AN INTRON RNA INTO DOUBLE-STRANDED DNA BY REVERSE SPLICING", NATURE, NATURE PUBLISHING GROUP, LONDON, GB, vol. 381, 23 May 1996 (1996-05-23), pages 332 - 335, XP002911808, ISSN: 0028-0836 *

Also Published As

Publication number Publication date
EP0996742A1 (en) 2000-05-03
CA2282737A1 (en) 1998-09-03
AU6676298A (en) 1998-09-18
AU748237B2 (en) 2002-05-30

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19990819

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB IT LI NL SE

RIN1 Information on inventor provided before grant (corrected)

Inventor name: BEAL, CLIFFORD, J.

Inventor name: MOHR, GEORG

Inventor name: GUO, HUATAO

Inventor name: ZIMMERLY, STEVE

Inventor name: LAMBOWITZ, ALAN, M.

A4 Supplementary search report drawn up and despatched

Effective date: 20051228

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION

17Q First examination report despatched

Effective date: 20080204

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080815