EP0991411A4 - Treatment for pulmonary fibrosis - Google Patents

Treatment for pulmonary fibrosis

Info

Publication number
EP0991411A4
EP0991411A4 EP97908480A EP97908480A EP0991411A4 EP 0991411 A4 EP0991411 A4 EP 0991411A4 EP 97908480 A EP97908480 A EP 97908480A EP 97908480 A EP97908480 A EP 97908480A EP 0991411 A4 EP0991411 A4 EP 0991411A4
Authority
EP
European Patent Office
Prior art keywords
treatment
pulmonary fibrosis
fibrosis
pulmonary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP97908480A
Other languages
German (de)
French (fr)
Other versions
EP0991411A1 (en
Inventor
Mark Pines
Arnon Nagler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hadasit Medical Research Services and Development Co
Agricultural Research Organization of Israel Ministry of Agriculture
Original Assignee
Hadasit Medical Research Services and Development Co
Agricultural Research Organization of Israel Ministry of Agriculture
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadasit Medical Research Services and Development Co, Agricultural Research Organization of Israel Ministry of Agriculture filed Critical Hadasit Medical Research Services and Development Co
Publication of EP0991411A1 publication Critical patent/EP0991411A1/en
Publication of EP0991411A4 publication Critical patent/EP0991411A4/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
EP97908480A 1997-03-31 1997-03-31 Treatment for pulmonary fibrosis Ceased EP0991411A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IL1997/000115 WO1998043642A1 (en) 1997-03-31 1997-03-31 Treatment for pulmonary fibrosis

Publications (2)

Publication Number Publication Date
EP0991411A1 EP0991411A1 (en) 2000-04-12
EP0991411A4 true EP0991411A4 (en) 2000-05-31

Family

ID=11061990

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97908480A Ceased EP0991411A4 (en) 1997-03-31 1997-03-31 Treatment for pulmonary fibrosis

Country Status (5)

Country Link
EP (1) EP0991411A4 (en)
JP (1) JP2001518062A (en)
AU (1) AU737094B2 (en)
CA (1) CA2285350A1 (en)
WO (1) WO1998043642A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4808997A (en) 1996-09-30 1998-04-24 Brigham And Women's Hospital Methods and compounds for treatment of abnormal uterine bleeding
HUP0300845A2 (en) * 1999-09-09 2003-07-28 Hadasit Medical Research Services And Development Company Ltd. Composition for promotion of wound healing, process for their preparation and its use
AU2013270622B2 (en) * 2007-01-21 2016-05-19 Agricultural Research Organization Composition and method for treating or preventing skeletal muscle fibrosis
AU2008206643B2 (en) 2007-01-21 2013-09-19 Agricultural Research Organization Composition and method for treating or preventing skeletal muscle fibrosis
CA2861840C (en) 2012-01-13 2020-12-15 President And Fellows Of Harvard College Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions
WO2019237125A1 (en) 2018-06-08 2019-12-12 The General Hospital Corporation Inhibitors of prolyl-trna-synthetase

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998034613A1 (en) * 1997-02-11 1998-08-13 Agricultural Research Organization Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization and for treating malignancies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2113229C (en) * 1994-01-11 1999-04-20 Mark Pines Anti-fibrotic quinazolinone-containing compositions and methods for the use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998034613A1 (en) * 1997-02-11 1998-08-13 Agricultural Research Organization Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization and for treating malignancies

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
NAGLER A ET AL: "Reduction in pulmonary fibrosis in vivo by halofuginone.", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, (1996 OCT) 154 (4 PT 1) 1082-6., XP000901078 *
NAGLER, A. (1) ET AL: "Reduction of pulmonary fibrosis by halofuginone, a specific inhibitor of collagen type I.", BLOOD, (1996) VOL. 88, NO. 10 SUPPL. 1 PART 1-2, PP. 416A. MEETING INFO.: THIRTY-EIGHTH ANNUAL MEETING OF THE AMERICAN SOCIETY OF HEMATOLOGY ORLANDO, FLORIDA, USA DECEMBER 6-10, 1996, XP000901181 *
See also references of WO9843642A1 *

Also Published As

Publication number Publication date
AU737094B2 (en) 2001-08-09
WO1998043642A1 (en) 1998-10-08
EP0991411A1 (en) 2000-04-12
CA2285350A1 (en) 1998-10-08
JP2001518062A (en) 2001-10-09
AU2042097A (en) 1998-10-22

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Legal Events

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