EP0984811A1 - Systeme d'insertion destine au placement et a l'assemblage endovasculaire d'un stent a couches multiples - Google Patents

Systeme d'insertion destine au placement et a l'assemblage endovasculaire d'un stent a couches multiples

Info

Publication number
EP0984811A1
EP0984811A1 EP99909659A EP99909659A EP0984811A1 EP 0984811 A1 EP0984811 A1 EP 0984811A1 EP 99909659 A EP99909659 A EP 99909659A EP 99909659 A EP99909659 A EP 99909659A EP 0984811 A1 EP0984811 A1 EP 0984811A1
Authority
EP
European Patent Office
Prior art keywords
stent
stent device
sheath
stage
stents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99909659A
Other languages
German (de)
English (en)
Other versions
EP0984811A4 (fr
Inventor
Howard J. Leonhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Vascular Inc
Original Assignee
World Medical Manufacturing Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by World Medical Manufacturing Corp filed Critical World Medical Manufacturing Corp
Publication of EP0984811A1 publication Critical patent/EP0984811A1/fr
Publication of EP0984811A4 publication Critical patent/EP0984811A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/9517Instruments specially adapted for placement or removal of stents or stent-grafts handle assemblies therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/89Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • A61F2002/075Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2002/825Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having longitudinal struts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2002/828Means for connecting a plurality of stents allowing flexibility of the whole structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0076Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008Fixation appliances for connecting prostheses to the body
    • A61F2220/0016Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0058Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements soldered or brazed or welded
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0066Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements stapled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028Shapes in the form of latin or greek characters
    • A61F2230/0054V-shaped

Definitions

  • the present invention generally relates to the area of blood vessel graft systems. More particularly, the present invention provides a catheter base delivery device for deployment of multi-stage stented grafts comprising multiple coaxial delivery mechanisms.
  • the coaxial delivery device enables the multiple stages of a stented graft to be assembled endovascularly.
  • aneurysms entailed removing part or all of the aneurysm and implanting a replacement prosthetic section into the lumen.
  • a synthetic or biomaterial graft is sutured end-to-end completely replacing the excised portion of the blood vessel.
  • surgical treatment or removal of the aneurysm involves significant invasive techniques, extended hospitalization and associated risk of complications. Complications include extensive blood loss, respiratory tract infections, wound infections, and renal failure. In addition, the mortality rates (8%) are significant for such surgeries.
  • a more contemporary method of treatment of aneurysms is to place a graft within the lumen of the weakened blood vessel via a catheter based device.
  • Conventional tubular aortic replacement sections are generally larger in diameter than the femoral artery and therefore can not be inserted through the lumen of the femoral artery.
  • the basic concept of a transluminal placement of an endovascular prosthesis for decreasing risk associated with the surgical repair of aortic aneurysms was proposed by Dotter (1969, Invest Radiol. 4:329-332). Since then, several investigators have studies the feasibility of different endovascular devices. For example Lazarus (U.S. Patent No.
  • 5,669,936 discloses a graft system having a capsule catheter that is deployed after femoral arteriotomy.
  • stent-grafts used clinically for treatment of abdominal and thoracic aortic aneurysms have required 18-F to 30-F delivery systems.
  • the large size of the delivery system necessitated surgical femoral arteriotomy and sometimes retroperitoneal left iliac arteriotomy or distal aorta aortotomy, general anesthesia, and high levels of multidisciplinary cooperation.
  • the system includes a single stage graft comprised of two Nitinol springs.
  • the two Nitinol springs are in physical communication with each other via a Nitinol connecting bar and are embedded in graft material at each end and covered completely by material so as to prevent direct exposure to bodily fluids or tissues.
  • the graft is deployed by using an elongated sheath introducer having an axially extending sheath passage for receiving the graft and maintaining it in a compressed condition.
  • a flexible push rod around the insertion catheter and within the sheath passage is used to push the graft out of the sheath during deployment.
  • one way to decrease the size of an endovascular device is to deploy the stented graft as separate parts.
  • none of the delivery devices available are suitable for delivery of a multi-stage stented graft by a single percutaneous insertion. There is thus, an ongoing need for graft delivery devices for treatment of aneurysms which requires minimal preparation and hospitalization.
  • the present invention provides a multi-stage stented graft that is easily introduced and implanted by percutaneous insertion for the treatment of aneurysms, and which circumvents the need for suturing or stapling to the wall of the blood vessel.
  • the various stages of the stented graft are assembled endovascularly. Accordingly, it is an object of the invention to provide a multistage stented graft for implantation into blood vessels.
  • Yet another object of the present invention is to provide a method for deployment of a multi-stage stented graft using a multiple coaxial delivery device, wherein the stented graft is assembled endovascularly from the multiple stages.
  • a still further object of the present invention is that the stented graft serves as a substrate for the growth of cells, lining the lumen of the blood vessels in the area of an aneurysm.
  • Fig. 1 is a perspective view of a two-stage stented graft 10 of the present invention.
  • Fig. 2 A is a perspective view of a first stage anchoring stent 12 of the two- stage stented graft shown in Fig. 1.
  • Fig. 2B is a perspective view of a second stage scaffolding stent 14 of the two-stage stented graft shown in Fig. 1.
  • Fig. 2C is a perspective view of the supporting frame 22 of the first stage of the stented graft shown in Fig. 1.
  • Fig. 2D is a magnified view of a portion of the supporting frame 22 shown in Fig. 1C illustrating the use of a single Nitinol wire for creating the frame.
  • Fig. 3 is a perspective view of a portion of the delivery device for the two- stage stented graft of the present invention.
  • Fig. 4 A is a perspective view of a hollow foamed tube 100.
  • Fig. 4B is a cross-sectional view along line 4B-4B of Fig. 4A.
  • endovascular stented grafts must meet certain strength and durability requirements, the goal of reducing their size profile by decreasing the size of their components is limited. By assembling the components of a stented graft endovascularly, the size of the delivery device is reduced without compromising flexibility.
  • the first embodiment of a stented graft of the present invention will be described in detail herein as a two-stage device. However, the present invention is not intended to be so limited and those skilled in the art after having read this specification will readily recognize that two or more stages are within the scope of the present invention.
  • a delivery device for the stented graft is also described. The delivery device enables the stented graft to be introduced into the vasculature through a single percutaneous insertion for subsequent endovascular assembly.
  • Fig. 1 shows a fully assembled two-stage stented graft 10 according to the present invention comprising a first stage anchoring stent 12 (Fig. 2 A) and a second stage scaffolding stent 14 (Fig. 2B).
  • the anchoring stent 12 comprises a tubular graft 16 having an annular side wall extending to opposed open ends 18 and 20 and a support frame 22 (Fig. 2C).
  • the synthetic material for the tubular graft 16 is pliable enough to substantially conform to the interior surface of a blood vessel being treated. Suitable synthetic materials include, but are not limited to, woven polyester, polytetrafluoroethylene (PTFE), microporous urethane, nylon and lycra.
  • a preferred fabric material is polyester.
  • the support frame 22 comprises a spaced apart first stent 24 and a second stent 26 connected to each other by a longitudinal bar 28. If desired, more than one connecting bar is provided.
  • the stents 24 and 26 and the connecting bar 28 can be made as separate parts that are subsequently secured to each other by bands 30 or by welding and the like.
  • the first and second stents 24, 26 and the intermediate connecting bar 28 can be made of a single wire 32 that is bent or otherwise formed to shape with its terminal ends 34 and 36 (shown in dashed lines in Fig. 2D) disposed proximate to each other and secured in place by a metal band 38. The ends of the wire 32 can also be welded together to complete the construction.
  • the size of the delivery device needed for placement of a self-expanding stented graft made of serpentine or Z-shaped undulations is determined by several factors. One is the required amount of radial force exerted by the stent. It is known that the radial force of a stent is an increased by increasing the size of the stent wire and/or the number of bends (Fallone et al, 1988, Invest. Radiol. 23:370-376). This means that a stent made of a larged diameter wire or having an increased number of bends requires a larger delivery device because the compressed diameter of the stent is also increased. Another factor influencing the required size of the delivery device is the diameter of the recipient blood vessel.
  • the double coaxial device 60 comprises two independent first and second coaxial delivery sheaths.
  • the first or proximal sheath 62 provides for the deployment of the first stage anchoring stent 12 shown in Fig. 2 A, while the distal or second sheath 64 provides for deployment of the scaffolding stent 14 within the lumen of the deployed anchoring stent. - 11 -
  • the frusto-conical member 78 is separate from stopper 70 and is preferably a tapered portion of the second sheath 64 that forms into the catheter 80.
  • the catheter 80 surrounds the pusher/holder wire 74 in a closely-spaced relationship and extends to a proximal end 82 adjacent to a proximal end 84 of the first sheath 62.
  • the proximal end 66 of the second sheath 64 is received inside the distal open end 86 of the first sheath 62 and in a movable relationship therewith.
  • the anchoring stent 12 is housed inside the first sheath 62 in a surrounding relationship with the catheter 80.
  • the anchoring stent 12 is retained in this position by the frusto-conical member 78 and a pusher tube 88 sized to movably fit inside the first sheath 62.
  • the catheter 80 is moved through the lumen of the anchoring stent 12 with the first stent 24 of the support frame 22 adjacent to the frusto-conical member 78.
  • the first sheath 62 is then moved over the anchoring stent 12.
  • the scaffolding stent 14 is positioned on the pusher/holder wire 74 intermediate the stoppers 72, - 12 -
  • the catheter 80 including the frusto-conical member 78 and the second sheath 64 are moved down the pusher/holder wire 74 until the distal open end 68 of the second sheath 64 abuts the distal stopper 72.
  • the scaffolding stent 14 and the second sheath 64 are now coaxial with the pusher /holder wire 74.
  • the first sheath 62, anchoring stent 12 and the catheter 80 are coaxial with the pusher/holder wire 74 and the distal open end 86 of the first sheath 62 surrounds the proximal end 64 of the second sheath 64.
  • the pusher tube 88 is moved over the pusher/holder wire 74 until its distal end is coaxial with and intermediate the distal open end 86 of the first sheath 62 and the proximal end 82 of the catheter 80.
  • the scaffolding stent 14 is moved in a proximal direction until it is centered between the stents 24, 26 of the anchoring stent 12.
  • the scaffolding stent 14 is now deployed by moving the catheter 80 in a proximal direction until the scaffolding stent 14 abuts the stationary stopper 70.
  • the catheter 80 is connected to the second sheath 64 by the frusto-conical member 78 and proximal movement of catheter 80 results in proximal movement of the second sheath 64 and the associated scaffolding stent 14.
  • the second sheath 64 is moved in a - 13 -
  • each of the anchoring stent 12 and the scaffolding stent 14 are deployed inside of the vasculature alone they will each exert a radial force of about 200 units of force, for example.
  • the combined radial force of the two forming the stented graft is at least about 80% of their combined radial force, or at least about 320 units of radial force. This increased radial force is provided without decreasing fatigue life.

Abstract

L'invention concerne un stent à couches multiples (10) destiné à être implanté dans un vaisseau sanguin. Chaque couche peut comporter des stents radialement compressibles (24, 26) munis ou dépourvus d'une enveloppe textile. Chaque couche peut également comporter un tube en mousse. Les couches multiples peuvent également être recouvertes d'une couche adhésive. Le stent à couches multiples (10) et les couches adhésives fournissent une surface permettant l'interposition de cellules et favorisent la cicatrisation. L'invention concerne également un système d'insertion coaxiale destiné à l'insertion et à l'assemblage endovasculaire dudit stent à couches multiples (10) au cours d'une seule intromission dans le système vasculaire.
EP99909659A 1998-02-26 1999-02-26 Systeme d'insertion destine au placement et a l'assemblage endovasculaire d'un stent a couches multiples Withdrawn EP0984811A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7638398P 1998-02-26 1998-02-26
US76383P 1998-02-26
PCT/US1999/004322 WO1999043378A1 (fr) 1998-02-26 1999-02-26 Systeme d'insertion destine au placement et a l'assemblage endovasculaire d'un stent a couches multiples

Publications (2)

Publication Number Publication Date
EP0984811A1 true EP0984811A1 (fr) 2000-03-15
EP0984811A4 EP0984811A4 (fr) 2005-03-09

Family

ID=22131662

Family Applications (2)

Application Number Title Priority Date Filing Date
EP99908586.3A Expired - Lifetime EP1061985B1 (fr) 1998-02-26 1999-02-26 Systeme permettant le deploiement et l'assemblage endovasculaire d'un stent a greffer multi-etages
EP99909659A Withdrawn EP0984811A4 (fr) 1998-02-26 1999-02-26 Systeme d'insertion destine au placement et a l'assemblage endovasculaire d'un stent a couches multiples

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP99908586.3A Expired - Lifetime EP1061985B1 (fr) 1998-02-26 1999-02-26 Systeme permettant le deploiement et l'assemblage endovasculaire d'un stent a greffer multi-etages

Country Status (5)

Country Link
US (3) US6280467B1 (fr)
EP (2) EP1061985B1 (fr)
AU (1) AU2881699A (fr)
CA (1) CA2321204C (fr)
WO (2) WO1999043378A1 (fr)

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US5609627A (en) * 1994-02-09 1997-03-11 Boston Scientific Technology, Inc. Method for delivering a bifurcated endoluminal prosthesis
US7959664B2 (en) * 1996-12-26 2011-06-14 Medinol, Ltd. Flat process of drug coating for stents
US20090239940A1 (en) * 1997-07-22 2009-09-24 Del Monte Federica Treating heart failure and ventricular arrhythmias
US6395019B2 (en) 1998-02-09 2002-05-28 Trivascular, Inc. Endovascular graft
US6280467B1 (en) * 1998-02-26 2001-08-28 World Medical Manufacturing Corporation Delivery system for deployment and endovascular assembly of a multi-stage stented graft
US6077296A (en) 1998-03-04 2000-06-20 Endologix, Inc. Endoluminal vascular prosthesis
US6176864B1 (en) * 1998-03-09 2001-01-23 Corvascular, Inc. Anastomosis device and method
JP4399585B2 (ja) * 1998-06-02 2010-01-20 クック インコーポレイティド 多辺管内医療器具
US7452371B2 (en) * 1999-06-02 2008-11-18 Cook Incorporated Implantable vascular device
WO1999065419A1 (fr) * 1998-06-19 1999-12-23 Endologix, Inc. Prothese endovasculaire bifurquee a dilatation automatique
EP1447057A1 (fr) * 1998-09-30 2004-08-18 Bard Peripheral Vascular, Inc. Mécanisme de mise en place d'extenseur implantable
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CA2321204C (fr) 2008-09-30
US6280467B1 (en) 2001-08-28
US6572645B2 (en) 2003-06-03
AU2881699A (en) 1999-09-15
WO1999043379A9 (fr) 1999-11-25
WO1999043379A1 (fr) 1999-09-02
US20020029075A1 (en) 2002-03-07
EP1061985A1 (fr) 2000-12-27
EP1061985B1 (fr) 2013-05-01
EP1061985A4 (fr) 2005-03-09
CA2321204A1 (fr) 1999-09-02
WO1999043378A1 (fr) 1999-09-02
EP0984811A4 (fr) 2005-03-09
US6123723A (en) 2000-09-26

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